Page last updated: 2024-08-17

isoflurophate and pralidoxime

isoflurophate has been researched along with pralidoxime in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's5 (20.83)18.2507
2000's4 (16.67)29.6817
2010's3 (12.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Torre, C1
Beasley, VR; Fikes, JD; Parker, AJ; Zachary, JF1
Hänninen, O; Kaliste-Korhonen, E; Ryhänen, R; Ylitalo, P1
Andre, RG; Golenda, CF; Roberts, DR; Wirtz, RA1
Doctor, BP; Rush, RS; Wolfe, AD1
Bowles, AM; Dretchen, KL; Raines, A1
Kasprzak, H; Salpeter, MM1
Green, PG; Kitchen, I1
Chowdhri, BL; Das Gupta, S; Ghosh, AK; Jaiswal, DK; Moorthy, MV; Pant, BP1
Glick, D; Liao, J; Loewenstein-Lichtenstein, Y; Norgaard-Pedersen, B; Schwarz, M; Soreq, H1
Chiou, GC; Hong, SJ; Rohde, BH1
Ghosh, AK; Jaiswal, DK; Sikder, AK1
Hänninen, O; Kaliste-Korhonen, E; Raushel, FM; Tuovinen, K1
KING, TO; POULSEN, E1
HOBBIGER, F; SADLER, PW1
EDERY, H1
Cometa, MF; Fortuna, S; Lorenzini, P; Meneguz, A; Palmery, M; Volpe, MT1
Barahona, MV; Sánchez-Fortún, S1
Hasan, MY; Kuca, K; Lorke, DE; Musilek, K; Nurulain, SM; Petroianu, GA1
Hasan, MY; Kuca, K; Lorke, DE; Nurulain, SM; Petroianu, GA; Schmitt, A1
Acharya, J; Jatav, PC; Karade, HN; Kumar, A; Kumar, P; Meena, MK; Swami, D1
Brewer, KL; Meggs, WJ; Tran, T1
Carrasco, M; Cuadrado, BL; Eterović, VA; Ferchmin, PA; Martins, AH; Pérez, D1
Clayman, CL; Ehinger, JK; Elmér, E; Hansson, MJ; Jang, DH; Janowska, JI; Jose, JS; Karlsson, M; Kilbaugh, TJ; McManus, MJ; Piel, S; Sheldon, M; Starr, J; Ward, JL1

Other Studies

24 other study(ies) available for isoflurophate and pralidoxime

ArticleYear
Biological responsiveness to cholinesterase inhibition: a test for exploring the developmental maturity of the cholinergic system.
    Journal of neuroscience research, 1976, Volume: 2, Issue:4

    Topics: Animals; Body Weight; Chick Embryo; Cholinesterase Inhibitors; Cholinesterases; Echothiophate Iodide; Isoflurophate; Lethal Dose 50; Mesylates; Parasympathetic Nervous System; Pralidoxime Compounds; Time Factors

1976
Clinical, biochemical, electrophysiologic, and histologic assessment of chlorpyrifos induced delayed neuropathy in the cat.
    Neurotoxicology, 1992,Fall, Volume: 13, Issue:3

    Topics: Animals; Antidotes; Atropine; Carboxylic Ester Hydrolases; Cats; Chlorpyrifos; Cholinesterases; Diazepam; Electromyography; Isoflurophate; Lymphocytes; Male; Motor Neurons; Nervous System Diseases; Neural Conduction; Pralidoxime Compounds; Time Factors

1992
Cold exposure decreases the effectiveness of atropine-oxime treatment in organophosphate intoxication in rats and mice.
    General pharmacology, 1989, Volume: 20, Issue:6

    Topics: Animals; Antidotes; Atropine; Carboxylic Ester Hydrolases; Cholinesterase Reactivators; Cold Temperature; Enzyme Reactivators; Isoflurophate; Lethal Dose 50; Mice; Obidoxime Chloride; Organophosphate Poisoning; Oximes; Pralidoxime Compounds; Rats; Rats, Inbred F344

1989
An insect bioassay as a primary screen for nerve agent antidotes.
    Military medicine, 1986, Volume: 151, Issue:5

    Topics: Animals; Antidotes; Atropine; Biological Assay; Cholinesterase Reactivators; Female; Houseflies; Isoflurophate; Nervous System; Physostigmine; Pralidoxime Compounds

1986
Kinetic investigations into the interactions of aprophen with cholinesterases and a carboxylesterase.
    Biochemical pharmacology, 1986, Dec-01, Volume: 35, Issue:23

    Topics: Acetylcholinesterase; Butyrylcholinesterase; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Humans; Isoflurophate; Kinetics; Phenylpropionates; Physostigmine; Pralidoxime Compounds; Serine

1986
Protection by phenytoin and calcium channel blocking agents against the toxicity of diisopropylfluorophosphate.
    Toxicology and applied pharmacology, 1986, Volume: 83, Issue:3

    Topics: Animals; Anticonvulsants; Atropine; Calcium Channel Blockers; Isoflurophate; Lethal Dose 50; Male; Mice; Phenytoin; Pralidoxime Compounds

1986
Recovery of acetylcholinesterase at intact neuromuscular junctions after in vivo inactivation with di-isopropylfluorophosphate.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:4

    Topics: Acetylcholinesterase; Animals; Autoradiography; Binding Sites; Bungarotoxins; Enzyme Activation; Enzyme Reactivators; Isoflurophate; Mice; Microscopy, Electron; Neuromuscular Junction; Pralidoxime Compounds

1985
Differential effects of di-isopropylfluorophosphate poisoning and its treatment on opioid antinociception in the mouse.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Animals; Atropine; Cholinesterase Reactivators; Isoflurophate; Male; Mice; Narcotics; Nociceptors; Pain; Pralidoxime Compounds

1983
Comparative studies of pralidoxime, trimedoxime, obidoxime and diethyxime in acute fluostigmine poisoning in rats.
    Die Pharmazie, 1982, Volume: 37, Issue:8

    Topics: Animals; Antidotes; Cholinesterases; Enzyme Activation; Enzyme Reactivators; Female; Isoflurophate; Obidoxime Chloride; Oximes; Pralidoxime Compounds; Rats; Trimedoxime

1982
Successive organophosphate inhibition and oxime reactivation reveals distinct responses of recombinant human cholinesterase variants.
    Brain research. Molecular brain research, 1995, Volume: 31, Issue:1-2

    Topics: Acetylcholinesterase; Alleles; Alternative Splicing; Animals; Butyrylcholinesterase; Catalysis; Cholinesterase Inhibitors; Cholinesterase Reactivators; Genetic Variation; Humans; Isoenzymes; Isoflurophate; Models, Molecular; Pralidoxime Compounds; Recombinant Proteins; Xenopus

1995
Use of C1300 neuroblastoma cells to evaluate the protective value of hexamethonium, trimethaphan, hemicholinium, and triethylcholine against diisopropyl phosphorofluoridate toxicity.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:1

    Topics: Animals; Cell Survival; Choline; Cholinergic Antagonists; Cholinesterase Reactivators; DNA, Neoplasm; Hemicholinium 3; Hexamethonium; Isoflurophate; Mice; Neoplasm Proteins; Neuroblastoma; Pralidoxime Compounds; RNA, Neoplasm; Trimethaphan; Tumor Cells, Cultured

1995
Quaternary salts of 3,3'-bis-pyridinium monooximes: synthesis and biological activity.
    Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:3

    Topics: Animals; Antidotes; Atropine; Cholinesterase Reactivators; Isoflurophate; Kinetics; Magnetic Resonance Spectroscopy; Mice; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Spectrophotometry, Infrared; Structure-Activity Relationship; Trimedoxime

1993
Phosphotriesterase, pralidoxime-2-chloride (2-PAM) and eptastigmine treatments and their combinations in DFP intoxication.
    Toxicology and applied pharmacology, 1996, Volume: 141, Issue:2

    Topics: Animals; Antidotes; Aryldialkylphosphatase; Brain; Cholinesterase Inhibitors; Esterases; Isoflurophate; Male; Mice; Physostigmine; Pralidoxime Compounds

1996
The action of an aldoxime (2-pyridine aldoxime methiodide) on acute alkylphosphate poisoning in mice.
    Archives internationales de pharmacodynamie et de therapie, 1958, Feb-01, Volume: 114, Issue:1

    Topics: Animals; Isoflurophate; Mice; Oximes; Parathion; Phosphates; Pralidoxime Compounds; Pyridines

1958
Protection against lethal organophosphate poisoning by quaternary pyridine aldoximes.
    British journal of pharmacology and chemotherapy, 1959, Volume: 14, Issue:2

    Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Hydroxylamines; Isoflurophate; Mice; Neostigmine; Organophosphate Poisoning; Oximes; Phosphates; Pralidoxime Compounds; Pyrans; Pyridines; Pyridinium Compounds

1959
Effects of organophosphorous compounds, oximes and atropine injected into the third ventricle of unanaesthetized dogs.
    British journal of pharmacology and chemotherapy, 1962, Volume: 18

    Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Dogs; Hydroxylamines; Insecticides; Isoflurophate; Oximes; Pralidoxime Compounds; Third Ventricle

1962
In vitro inhibitory effect of aflatoxin B1 on acetylcholinesterase activity in mouse brain.
    Toxicology, 2005, Jan-05, Volume: 206, Issue:1

    Topics: Acetylcholinesterase; Aflatoxin B1; Animals; Binding, Competitive; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Isoenzymes; Isoflurophate; Kinetics; Male; Mice; Pralidoxime Compounds; Substrate Specificity; Time Factors

2005
Toxicity and characterization of cholinesterase-inhibition induced by diisopropyl fluorophosphate in Artemia salina larvae.
    Ecotoxicology and environmental safety, 2009, Volume: 72, Issue:3

    Topics: Animals; Artemia; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Isoflurophate; Larva; Longevity; Muscarinic Antagonists; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Toxicity Tests, Acute; Water Pollutants, Chemical

2009
Eight new bispyridinium oximes in comparison with the conventional oximes pralidoxime and obidoxime: in vivo efficacy to protect from diisopropylfluorophosphate toxicity.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:7

    Topics: Animals; Antidotes; Cholinesterase Inhibitors; Drug Antagonism; Injections, Intraperitoneal; Isoflurophate; Lethal Dose 50; Longevity; Obidoxime Chloride; Pralidoxime Compounds; Rats; Rats, Wistar; Structure-Activity Relationship

2008
Efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate: comparison with pralidoxime, obidoxime, trimedoxime, methoxime, and HI-6.
    Toxicology mechanisms and methods, 2009, Volume: 19, Issue:4

    Topics: Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate; Male; Obidoxime Chloride; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime

2009
In vivo protection of diisopropylphosphorofluoridate (DFP) poisoning by three bis-quaternary 2 -(hydroxyimino) -N -(pyridin-3-yl) acetamide derivatives in Swiss mice.
    Cellular and molecular biology (Noisy-le-Grand, France), 2014, Oct-25, Volume: 60, Issue:3

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate; Male; Mice; Oximes; Poisoning; Pralidoxime Compounds

2014
Chronic Treatment with Naltrexone Prevents Memory Retention Deficits in Rats Poisoned with the Sarin Analog Diisopropylfluorophosphate (DFP) and Treated with Atropine and Pralidoxime.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2015, Volume: 11, Issue:4

    Topics: Animals; Atropine; Female; Isoflurophate; Memory Disorders; Naltrexone; Pralidoxime Compounds; Rats; Rats, Long-Evans

2015
Neuroprotection Against Diisopropylfluorophosphate in Acute Hippocampal Slices.
    Neurochemical research, 2015, Volume: 40, Issue:10

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Hippocampus; Isoflurophate; Male; Neuroprotection; Neuroprotective Agents; Pralidoxime Compounds; Rats, Sprague-Dawley; Synapses

2015
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
    Scientific reports, 2022, 11-25, Volume: 12, Issue:1

    Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphate Poisoning; Prodrugs; Rats; Rodentia; Succinates; Succinic Acid

2022