isoflurophate has been researched along with paraoxon in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (44.80) | 18.7374 |
| 1990's | 36 (28.80) | 18.2507 |
| 2000's | 21 (16.80) | 29.6817 |
| 2010's | 11 (8.80) | 24.3611 |
| 2020's | 1 (0.80) | 2.80 |
| Authors | Studies |
|---|---|
| Bleyer, H; Grisk, A; Möritz, KU | 1 |
| Kolattukudy, PE; Purdy, RE | 1 |
| Koning, LJ; van der Meer, C | 1 |
| Lang, S; Mandell, B; Rodman, JS; Schlesinger, P; Stahl, P | 1 |
| Brookes, N; Goldberg, AM | 1 |
| Heffron, PF; Hobbiger, F | 1 |
| Cisson, CM; Wilson, BW | 1 |
| Johnson, MK | 2 |
| Burgess-Miller, SK; Main, AR; McKnelly, SC | 1 |
| DeCaprio, AP; Olajos, EJ; Rosenblum, I | 1 |
| Fonnum, F; Lund-Karlsen, R | 1 |
| Bak, W; Borkowska, G; Faff, J | 1 |
| Dettbarn, WD; Hoskin, FC | 1 |
| Golovko, AI; Kliuntina, TV; Nikolaeva, TV; Sofronov, GA | 1 |
| Chemnitius, GC; Chemnitius, JM; Haselmeyer, KH; Kreuzer, H; Zech, R | 1 |
| Dacre, JC; Henderson, JD; Higgins, RJ; Wilson, BW | 1 |
| Muona, O; Nelson, SR; Pazdernik, TL; Samson, FE; Savolainen, KM | 1 |
| Banerjee, J; Bhattacharya, S; Ghosh, N; Ghosh, P; Mitra, S | 1 |
| Fonnum, F; Gaustad, R; Johnsen, H | 1 |
| Ashani, Y; Frolow, F; Harel, M; Silman, I; Su, CT; Sussman, JL | 1 |
| Banerjee, S; Finlay, TH; Katz, J; Levitz, M | 1 |
| Capodicasa, E; Lotti, M; Moretto, A; Peraica, M | 1 |
| Bisso, GM; Michalek, H; Volpe, MT | 1 |
| Forster, JS; Hammond, PS | 1 |
| Hollingsworth, PJ | 1 |
| Ishikawa, Y; McNamee, MG; Thomas, TC; Wilson, BW | 1 |
| Johnson, MK; Meredith, C | 1 |
| Barril, JB; Pellin, MC; Vilanova, E | 1 |
| Domino, EF | 1 |
| Novak, R; Padilla, S | 1 |
| Goss, LB; Moore, MT; Reveley, JW; Sabourin, TD | 1 |
| Abou-Donia, MB; Carrington, CD | 4 |
| Flynn, CJ; Wecker, L | 1 |
| Becker, CE; Lotti, M; Spear, RC; Wei, ET | 1 |
| Chu, FS; Wei, RD | 1 |
| Booth, GM; Connor, J; Larsen, JR; Metcalf, RA | 1 |
| Ecobichon, DJ | 2 |
| Zech, R; Zürcher, K | 1 |
| Comeau, AM; Ecobichon, DJ | 1 |
| Schmidt, J; Wolf, H | 1 |
| Patil, BG; Ramachandran, BV | 1 |
| Marynen-de Preter, L | 1 |
| Hipps, PP; Nelson, DR | 1 |
| Dettbarn, WD; Welsch, F | 1 |
| Kumbier, E; Liebmann, H; Matthies, H | 1 |
| Dierkes-Tizek, U; Glaser, U; Hettwer, H; Oldiges, H | 1 |
| Casida, JE; Seifert, J | 1 |
| Chow, E; Ishikawa, Y; McChesney, M; McNamee, MG; Wilson, BW | 1 |
| Cain, K; Reiner, E; Williams, DG | 1 |
| Ketterman, A; Lotti, M; Talcott, RE; Waskell, L | 1 |
| Chow, E; Cisson, CM; Ishikawa, Y; Wilson, BW | 1 |
| Chemnitius, JM; Zech, R | 1 |
| Williams, DG | 1 |
| Lüllmann, H; Schmaus, H; Staemmler, C; Ziegler, A | 1 |
| Brookes, N; Burt, DR; Goldberg, AM | 1 |
| Amorico, L; Bignami, G; de Acetis, L; Giardini, V | 1 |
| Johnson, MK; Williams, DG | 1 |
| Johnson, MK; Lotti, M | 1 |
| Main, AR; Miller, SK; Rush, RS | 1 |
| Blusztajn, JK; Davis, RO | 1 |
| Barril, J; Escudero, MA; Tormo, N; Vilanova, E | 1 |
| Andersen, ME; Clewell, HJ; Conolly, RB; Gearhart, JM; Jepson, GW | 1 |
| Aslanian, D; Gróf, P; Masson, P; Renault, F | 1 |
| Anis, NA; Dehlawi, MS; Eldefrawi, AT; Eldefrawi, ME; Valdes, JJ | 1 |
| Seifert, J; Wilson, BW | 1 |
| Reig, JA; Sogorb, MA; Vilanova, E; Viniegra, S | 1 |
| De Bleecker, J; De Reuck, J; Lison, D; Van Den Abeele, K; Willems, J | 1 |
| Russell, RJ; Walker, VK; Whyard, S | 1 |
| Costa, LG; Ehrich, M; Intropido, L | 1 |
| Funk, KA; Henderson, JD; Higgins, RJ; Liu, CH; Wilson, BW | 1 |
| Díaz-Alejo, N; Gimeno, JR; Sogorb, MA; Tormo, N; Vilanova, E | 1 |
| Funk, KA; Higgins, RJ; Liu, CH; Wilson, BW | 1 |
| Chemnitius, JM; Dewald, K; Kreuzer, H; Zech, R | 1 |
| Abou-Donia, MB; Knoth-Anderson, J | 1 |
| Barril, J; Diaz-Alejo, N; Tormo, N; Vilanova, E | 1 |
| Casida, JE; Wu, SY | 1 |
| Quintanar, JL; Sogorb, MA; Vilanova, E; Viniegra, S | 1 |
| Blain, PG; Charlton, C; de Blaquière, GE; Kelly, SS; Mutch, E; Williams, FM | 1 |
| Blain, PG; de Blaquière, GE; Kelly, SS; Williams, FM | 1 |
| Bas, S; Gutiérrez, LM; Sogorb, MA; Vilanova, E; Viniegra, S | 1 |
| Céspedes, MV; Escudero, MA; Vilanova, E | 1 |
| Mahoney, HJ; McCulloch, JK; Raushel, FM; Watkins, LM | 1 |
| Barril, J; Céspedes, MV; Escudero, MA; Sogorb, MA; Vicedo, JL; Vilanova, E | 1 |
| Dettbarn, WD; Milatovic, D; Yang, ZP | 1 |
| Makhaeva, GF; Malygin, VV | 1 |
| Nagy, A; Plonowski, A; Schally, AV | 1 |
| Ballesteros, A; Gill, I | 1 |
| Ashman, W; Gopal, S; Mulbry, W; Rastogi, V | 1 |
| Decker, S; Klabunde, KJ; Koper, O; Rajagopalan, S | 1 |
| Barhoumi, R; Burghardt, RC; Donnelly, KC; Hong, MS; Hong, SJ; Tiffany-Castiglioni, E; Venkatraj, V; Wild, JR | 1 |
| Barril, J; Estévez, J; Garcia-Pérez, AG; Vilanova, E | 1 |
| Halámek, J; Kernchen, F; Makower, A; Scheller, FW; Skládal, P | 1 |
| BETHE, K; ERDMANN, WD; LENDLE, L; SCHMIDT, G | 1 |
| ERDMANN, WD; LATKI, O | 1 |
| Carrera, V; Quesada, E; Sogorb, MA; Vilanova, E | 1 |
| Cho, T; Tiffany-Castiglioni, E | 1 |
| Chiba, T; Gomi, K; Handa, S; Hirokawa, K; Ishigami, A; Kajiyama, N; Kondo, Y; Kubo, S; Maruyama, N; Shimokado, K | 1 |
| Ehrich, M; Jortner, BS; Knight, K; Massicotte, C; Van der Schyf, CJ | 1 |
| Chang, PA; Chen, R; Wu, YJ | 1 |
| Cho, TM; Donnelly, KC; Tiffany-Castiglioni, E; Wild, JR | 1 |
| Carrera, V; García-Fernández, AJ; Quesada, E; Romero, D; Sogorb, MA; Vilanova, E | 1 |
| Froment, MT; Lockridge, O; Loiodice, M; Masson, P; Nachon, F; Poyot, T; Schopfer, LM; Wieseler, S | 1 |
| Carrera, V; Castell, JV; Quesada, E; Vilanova, E | 1 |
| Barhoumi, R; Datta, A; Pal, R; Qian, Y; Tiffany-Castiglioni, E; Venkatraj, J; Wild, JR | 1 |
| Ramanathan, M; Simonian, AL | 1 |
| Richmond, GS; Smith, TK | 1 |
| Chang, PA; Long, DX; Wu, YJ | 1 |
| Jun, D; Jung, YS; Kuca, K; Oh, KA; Park, NJ; Park, NS | 1 |
| Ehrich, M; Kepley, CL; Li, Y; Van Tassell, R; Zhou, Z | 1 |
| Estévez, J; Mangas, I; Vilanova, E | 1 |
| Arnold, ME; Buzescu, A; Fung, EN; Zeng, J; Zheng, N | 1 |
| Balint, CA; Cowan, ML; Kapur, J; Sun, C; Todorovic, MS | 1 |
| Estévez, J; Mangas, I; Sogorb, MÁ; Vilanova, E | 1 |
| Acharya, JR; Ghosh, KK; Gupta, B; Kuca, K; Sharma, R; Singh, N | 1 |
| Bal-Price, A; Collotta, A; Fabbri, M; Gribaldo, L; Harris, G; Pamies, D; Scelfo, B; Sogorb, MA; Vilanova, E | 1 |
| Estévez, J; França, TC; Komives, E; Mangas, I; Radić, Z; Taylor, P; Vilanova, E | 1 |
| Del Río, E; Estévez, J; Fuster, E; Sogorb, MA; Vilanova, E | 1 |
| Emerick, GL; Fernandes, LS; Ferreira, RS; Santos, ACD; Santos, NAGD | 1 |
| Del Río, E; Estévez, J; González-González, M; Sogorb, MA; Vilanova, E | 1 |
| Gunst, JD; Hasselstrøm, JB; Kjolby, M; Søgaard, OS; Sørensen, LK | 1 |
125 other study(ies) available for isoflurophate and paraoxon
| Article | Year |
|---|---|
[The effect of diisopropylfluorphosphate on the adenylate cyclase activity and the 3',5'-AMP content of myocardium and brain].
Topics: Adenylyl Cyclases; Animals; Atropine; Brain; Cyclic AMP; Dimethoate; Female; Heart; Isoflurophate; Male; Paraoxon; Rats | 1976 |
Hydrolysis of plant cuticle by plant pathogens. Properties of cutinase I, cutinase II, and a nonspecific esterase isolated from Fusarium solani pisi.
Topics: Binding Sites; Carboxylic Ester Hydrolases; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Fusarium; Hydrogen-Ion Concentration; Hydrolases; Hydrolysis; Hydroxy Acids; Isoenzymes; Isoflurophate; Kinetics; Lipid Metabolism; Paraoxon; Plants; Polymers; Serine; Structure-Activity Relationship; Sulfhydryl Reagents | 1975 |
The cause of death of Palaemonetes varians (Leach, 1814) treated with cholinesterase inhibitors.
Topics: Animals; Crustacea; Death; Dose-Response Relationship, Drug; Heart; Heart Arrest; Heart Rate; Isoflurophate; Organophosphorus Compounds; Paraoxon; Parathion; Soman; Time Factors | 1975 |
Different forms of rat beta-glucuronidase with rapid and slow clearance following intravenous injection: selective serum enhancement of slow clearance forms by organophosphate compounds.
Topics: Animals; Chromatography, Affinity; Digestive System Physiological Phenomena; Female; Glucuronidase; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Liver; Lysosomes; Microsomes, Liver; Paraoxon; Rats | 1975 |
Choline acetyltransferase activity of spinal cord cell cultures is increased by diisopropylphosphorofluoridate.
Topics: Animals; Cells, Cultured; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Embryo, Mammalian; Isoflurophate; Male; Mice; Paraoxon; Spinal Cord; Stimulation, Chemical | 1979 |
Relationship between inhibition of acetylcholinesterase and response of the rat phrenic nerve-diaphragm preparation to indirect stimulation at higher frequencies.
Topics: Animals; Cholinesterase Inhibitors; Diaphragm; Electric Stimulation; Isoflurophate; Male; Muscle Contraction; Neuromuscular Junction; Paraoxon; Phrenic Nerve; Rats | 1979 |
Recovery of acetylcholinesterase in cultured chick embryo muscle treated with paraoxon.
Topics: Acetylcholinesterase; Animals; Chick Embryo; Cholinesterase Inhibitors; Creatine Kinase; Culture Techniques; Isoenzymes; Isoflurophate; Muscles; Paraoxon; Time Factors | 1977 |
Improved assay of neurotoxic esterase for screening organophosphates for delayed neurotoxicity potential.
Topics: Animals; Brain; Chickens; Esterases; Isoflurophate; Methods; Organophosphorus Compounds; Paraoxon | 1977 |
A subunit-sized butyrylcholinesterase present in high concentrations in pooled rabbit serum.
Topics: Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Chromatography, Gel; Horses; Humans; Isoflurophate; Molecular Weight; Paraoxon; Rabbits; Substrate Specificity; Thiocholine | 1977 |
Central and peripheral neurotoxic esterase activity and dose-response relationship in adult hens after acute and chronic oral administration of diisopropyl fluorophosphate.
Topics: Animals; Brain; Chickens; Cholinesterases; Dose-Response Relationship, Drug; Esterases; Female; Isoflurophate; Nervous System Diseases; Paraoxon; Sciatic Nerve; Time Factors | 1978 |
The effect of locally applied cholinesterase inhibitors and oximes on the acetylcholinesterase activity in different parts of the guinea-pig eye.
Topics: Acetylcholinesterase; Animals; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Eye; Guinea Pigs; Isoflurophate; Obidoxime Chloride; Oculomotor Muscles; Oximes; Paraoxon; Sarin | 1976 |
Therapeutic effects of some cholinolytics in organophosphate intoxications.
Topics: Animals; Antidotes; Atropine; Benzilates; Dichlorvos; Echothiophate Iodide; Isoflurophate; Lethal Dose 50; Mice; Muscle, Smooth; Organophosphate Poisoning; Oxotremorine; Paraoxon; Parasympatholytics; Piperidines; Rats | 1976 |
Toxicity of DFP and related compounds to squids in relation to cholinesterase inhibition and detoxifying enzyme levels.
Topics: Animals; Behavior, Animal; Cholinesterase Inhibitors; Decapodiformes; Dimethylamines; Isoflurophate; Lethal Dose 50; Organothiophosphorus Compounds; Paraoxon; Physostigmine; Stimulation, Chemical | 1975 |
[Effects of diisopropylfluorophosphate, paraoxon and dichlophos on [3H] quinuclidinyl benzylate binding to the rat striatum synaptic membranes].
Topics: Animals; Corpus Striatum; Dichlorvos; In Vitro Techniques; Isoflurophate; Male; Paraoxon; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Seizures; Synaptosomes | 1992 |
Cholinesterases of heart muscle. Characterization of multiple enzymes using kinetics of irreversible organophosphorus inhibition.
Topics: Acetylthiocholine; Animals; Butyrylthiocholine; Cholinesterase Inhibitors; Cholinesterases; Female; Heart Ventricles; Isoflurophate; Kinetics; Male; Myocardium; Paraoxon; Swine | 1992 |
Neurotoxicity of acute and repeated treatments of tabun, paraoxon, diisopropyl fluorophosphate and isofenphos to the hen.
Topics: Acetylcholinesterase; Animals; Body Weight; Butyrylcholinesterase; Chickens; Cholinesterase Inhibitors; Cholinesterases; Creatine Kinase; Female; Injections, Intramuscular; Insecticides; Isoflurophate; Motor Activity; Organophosphates; Organothiophosphorus Compounds; Paraoxon; Spinal Cord; Tibial Nerve | 1992 |
Lithium modifies convulsions and brain phosphoinositide turnover induced by organophosphates.
Topics: Animals; Brain; Chlorides; Chromatography, Gas; Drug Synergism; Inositol Phosphates; Insecticides; Isoflurophate; Lithium; Lithium Chloride; Male; Paraoxon; Rats; Rats, Inbred Strains; Seizures; Soman | 1991 |
Inhibition of human fetal brain acetylcholinesterase: marker effect of neurotoxicity.
Topics: Acetylcholinesterase; Brain; Carbaryl; Chlorpromazine; Cholinesterase Inhibitors; Culture Techniques; Embryo, Mammalian; Humans; Isoflurophate; Kinetics; Paraoxon; Physostigmine | 1991 |
Carboxylesterases in guinea pig. A comparison of the different isoenzymes with regard to inhibition by organophosphorus compounds in vivo and in vitro.
Topics: Animals; Carboxylic Ester Hydrolases; Dose-Response Relationship, Drug; Guinea Pigs; Injections, Intraperitoneal; Injections, Subcutaneous; Isoelectric Focusing; Isoenzymes; Isoflurophate; Liver; Lung; Male; Organophosphorus Compounds; Paraoxon | 1991 |
Refined crystal structures of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin.
Topics: Alkylation; Chymotrypsin; Enzyme Activation; Hydrogen Bonding; Isoflurophate; Kinetics; Models, Molecular; Organophosphorus Compounds; Paraoxon; Solvents; X-Ray Diffraction | 1991 |
Purification and properties of an esterase from human breast cyst fluid.
Topics: Anti-Bacterial Agents; Blotting, Western; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Esters; Estradiol; Female; Fibrocystic Breast Disease; Freezing; Humans; Isoflurophate; Lactones; Paraoxon; Potassium; Sodium Fluoride | 1991 |
Age sensitivity to organophosphate-induced delayed polyneuropathy. Biochemical and toxicological studies in developing chicks.
Topics: Age Factors; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Dichlorvos; Isoflurophate; Paraoxon; Peripheral Nerves; Spinal Cord | 1991 |
In vivo and in vitro effects of diisopropyl fluorophosphate and paraoxon on individual molecular forms of rat brain acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Brain; Isoenzymes; Isoflurophate; Male; Molecular Weight; Paraoxon; Rats; Rats, Inbred Strains; Reference Values | 1990 |
A microassay-based procedure for measuring low levels of toxic organophosphorus compounds through acetylcholinesterase inhibition.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Isoflurophate; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Reference Standards; Soman; Spectrophotometry | 1989 |
Chronic treatment with cholinesterase inhibitors increases alpha 2-adrenoceptors in rat brain.
Topics: Animals; Brain; Cholinesterase Inhibitors; Clonidine; Depression; Histocytochemistry; Isoflurophate; Male; Neostigmine; Paraoxon; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tritolyl Phosphates | 1988 |
Correlation of neuropathy target esterase activity with specific tritiated di-isopropyl phosphorofluoridate-labelled proteins.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Centrifugation, Density Gradient; Chick Embryo; Isoflurophate; Membrane Proteins; Microsomes; Paraoxon | 1989 |
Species distribution of paraoxon-resistant brain polypeptides radiolabelled with diisopropyl phosphorofluoridate ([3H]DiPF): electrophoretic assay for the aged polypeptide of [3H]DiPF-labelled neuropathy target esterase.
Topics: Aging; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Female; Guinea Pigs; Isoflurophate; Paraoxon; Peptides; Rats; Sheep; Swine; Tritium | 1989 |
Sensitivity and selectivity of compounds interacting with neuropathy target esterase. Further structure-activity studies.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Isoflurophate; Paraoxon; Structure-Activity Relationship; Substrate Specificity | 1988 |
Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Female; Isoflurophate; Nerve Regeneration; Organophosphorus Compounds; Paraoxon; Sciatic Nerve; Sulfones | 1988 |
Comparative seizure inducing properties of various cholinesterase inhibitors: antagonism by diazepam and midazolam.
Topics: Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Diazepam; Isoflurophate; Male; Midazolam; Neostigmine; Paraoxon; Physostigmine; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Seizures | 1987 |
An in vitro comparison of rat and chicken brain neurotoxic esterase.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Hydrogen-Ion Concentration; In Vitro Techniques; Isoflurophate; Male; Molecular Weight; Organophosphorus Compounds; Paraoxon; Rats; Species Specificity; Tritium | 1986 |
Distribution of neurotoxic esterase activity in the brain of control and diisopropyl phosphorofluoridate-treated hens: in vivo and in vitro exposure.
Topics: Animals; Atropine; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Interactions; Female; Hydrolysis; Injections, Subcutaneous; Isoflurophate; Paraoxon; Physostigmine | 1986 |
Kinetics of substrate hydrolysis and inhibition by mipafox of paraoxon-preinhibited hen brain esterase activity.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Cell Membrane; Chickens; Female; Hydrolysis; Isoflurophate; Kinetics; Models, Chemical; Paraoxon; Phenylacetates; Valerates | 1986 |
Elevated choline levels in brain. A non-cholinergic component of organophosphate toxicity.
Topics: Acetylcholinesterase; Animals; Brain; Choline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Isoflurophate; Male; Microwaves; Paraoxon; Rats; Rats, Inbred Strains; Sarin; Soman | 1986 |
Neurotoxic esterase in rooster testis.
Topics: Animals; Ataxia; Brain; Carboxylic Ester Hydrolases; Chickens; Isoflurophate; Male; Organophosphorus Compounds; Paraoxon; Testis; Testosterone | 1985 |
Modification of in vitro metabolism of T-2 toxin by esterase inhibitors.
Topics: Animals; Chromatography, Thin Layer; Esterases; Hydroxylation; Hydroxymercuribenzoates; In Vitro Techniques; Isoflurophate; Liver; Male; Paraoxon; Phenylmethylsulfonyl Fluoride; Physostigmine; Rats; Rats, Inbred Strains; Sesquiterpenes; Sodium Fluoride; Swine; T-2 Toxin | 1985 |
Characterization of [3H]di-isopropyl phosphorofluoridate-binding proteins in hen brain. Rates of phosphorylation and sensitivity to neurotoxic and non-neurotoxic organophosphorus compounds.
Topics: Animals; Brain; Chickens; Electrophoresis, Polyacrylamide Gel; Female; Isoflurophate; Membrane Proteins; Paraoxon; Phenylmethylsulfonyl Fluoride; Phosphorylation; Proteins | 1985 |
Paraoxon reversibly inhibits neurotoxic esterase.
Topics: Animals; Binding, Competitive; Carboxylic Ester Hydrolases; Catalysis; Chickens; Female; Isoenzymes; Isoflurophate; Paraoxon | 1985 |
A comparative study of the effects of selective inhibitors on esterase isozymes from the mosquito Anopheles punctipennis.
Topics: Acetates; Aldicarb; Alleles; Animals; Anopheles; Carbamates; Carbaryl; Carbofuran; Cholinesterase Inhibitors; Dichlorvos; Electrophoresis, Polyacrylamide Gel; Esterases; Fonofos; Isoenzymes; Isoflurophate; Naphthols; Organophosphorus Compounds; Paraoxon; Physostigmine; Thiocarbamates | 1973 |
Characterization of the esterases of feline serum.
Topics: Acetylcholinesterase; Animals; Butyrates; Calcium; Cats; Cholinesterases; Chromatography, Gel; Cobalt; Dichlorvos; Edetic Acid; Electrophoresis, Starch Gel; Esterases; Female; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Isoflurophate; Kinetics; Magnesium; Male; Naphthols; Nitrophenols; Paraoxon; Physostigmine | 1974 |
[Substrate specificity and the stability of a phosphoryl phosphatase from rabbit serum].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Chromatography, Gel; Diphosphates; Drug Stability; Hydrogen-Ion Concentration; Insecticides; Isoflurophate; Kinetics; Nitrophenols; Organophosphorus Compounds; Paraoxon; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Rabbits; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1973 |
Pseudocholinesterases of mammalian plasma: physicochemical properties and organophosphate inhibition in eleven species.
Topics: Animals; Cats; Chemical Phenomena; Chemistry, Physical; Cholinesterase Inhibitors; Cholinesterases; Cricetinae; Dichlorvos; Dogs; Female; Goats; Guinea Pigs; Haplorhini; Horses; Humans; Isoflurophate; Male; Mice; Organophosphorus Compounds; Paraoxon; Protein Binding; Rabbits; Rats; Sex Factors; Species Specificity; Swine | 1973 |
[Influence of atropine and cholinesterase inhibitors on brain potentials caused by dental pulp stimulation].
Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Dental Pulp; Electric Stimulation; Evoked Potentials; Female; Galantamine; Isoflurophate; Male; Paraoxon; Physostigmine; Rabbits | 1972 |
Effect of diisopropyl phosphorofluoridate & paraoxon in vivo & in vitro on the sodium & potassium contents of mouse liver tissue.
Topics: Acetylcholine; Animals; Atropine; In Vitro Techniques; Insecticides; Isoflurophate; Liver; Mice; Ouabain; Paraoxon; Physostigmine; Potassium; Sodium; Water | 1972 |
[Ophthalmological use of organophosphates and their effects on the enzyme system].
Topics: Acetylcholinesterase; Anesthesia; Child; Cholinesterase Inhibitors; Echothiophate Iodide; Erythrocytes; Eye; Eye Diseases; Female; Humans; Insecticides; Isoflurophate; Male; Miotics; Paraoxon; Succinylcholine | 1972 |
Characterization of canine hepatic and renal esterases.
Topics: Acetates; Animals; Butyrates; Cations, Divalent; Cholinesterases; Dichlorvos; Dogs; Electrophoresis, Starch Gel; Esterases; Esters; Female; Hydrogen-Ion Concentration; Isoflurophate; Kidney; Kinetics; Liver; Male; Naphthols; Nitrophenols; Paraoxon; Propionates; Trichlorfon | 1973 |
Esterases from the midgut and gastric caecum of the American cockroach, Periplaneta americana (L.). Isolation and characterization.
Topics: Animals; Calorimetry; Chromatography, Gel; Chromatography, Ion Exchange; Cockroaches; Digestive System; Drug Stability; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Esterases; Hot Temperature; Hydrogen-Ion Concentration; Insecticides; Isoflurophate; Kinetics; Macromolecular Substances; Molecular Weight; Paraoxon; Physostigmine; Spectrophotometry; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics | 1974 |
Inhibition of cholinesterases of rat diaphragm muscle by organophosphates and spontaneous recovery of enzyme activity in vitro.
Topics: Animals; Axons; Chloramphenicol; Cholinesterase Inhibitors; Cycloheximide; Diaphragm; Echothiophate Iodide; Enzyme Activation; Female; Isoflurophate; Kinetics; Male; Muscles; Nephropidae; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Rats | 1972 |
[Effect of phenelzine on the toxicity of cholinergic drugs modified by reserpine].
Topics: Animals; Cholinesterase Inhibitors; Drug Interactions; Female; Galantamine; Isoflurophate; Lethal Dose 50; Male; Mice; Monoamine Oxidase Inhibitors; Neostigmine; Paraoxon; Parasympathomimetics; Phenelzine; Physostigmine; Reserpine; Toxicology | 1971 |
[The effect of organophosphates on heart ATPase in the rat].
Topics: Adenosine Triphosphatases; Animals; Antidotes; Atropine; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Electrophysiology; Female; Isoflurophate; Kinetics; Myocardium; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Parathion; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1984 |
Neural microtubular and lysosomal phenyl valerate esterases and proteases in relation to organophosphate-induced delayed neurotoxicity.
Topics: Acid Phosphatase; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cytoplasm; Glucuronidase; In Vitro Techniques; Isoflurophate; Lysosomes; Microtubules; Neurons; Organophosphorus Compounds; Paraoxon; Peptide Hydrolases; Rats; Spinal Cord | 1984 |
The correlation between the recovery rate of neurotoxic esterase activity and sensitivity to organophosphorus-induced delayed neurotoxicity.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Diazepam; Female; Isoflurophate; Male; Paraoxon; Phenylmethylsulfonyl Fluoride; Radial Nerve; Rats; Rats, Inbred Strains; Sciatic Nerve | 1984 |
Separation of paraoxon and mipafox sensitive esterases by sucrose density gradient sedimentation.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Centrifugation, Density Gradient; Chick Embryo; Chickens; Isoflurophate; Paraoxon; Spinal Cord | 1983 |
The identification and characterization of two separate carboxylesterases in guinea-pig serum.
Topics: Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Cholinesterases; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Isoelectric Focusing; Isoenzymes; Isoflurophate; Neostigmine; Nitrophenols; Organophosphorus Compounds; Paraoxon | 1983 |
Meperidine carboxylesterase in mouse and human livers.
Topics: Acetone; Animals; Carboxylic Ester Hydrolases; Chemical Phenomena; Chemistry; Cytosol; Humans; Isoflurophate; Liver; Mice; Microsomes, Liver; Mitochondria, Liver; Paraoxon; Species Specificity | 1983 |
Multilevel studies of organophosphate toxicity.
Topics: Acetylcholinesterase; Animals; Carboxylic Ester Hydrolases; Cells, Cultured; Coturnix; Isoflurophate; Muscles; Nervous System Diseases; Paraoxon; Tissue Distribution | 1983 |
Inhibition of brain carboxylesterases by neurotoxic and nonneurotoxic organophosphorus compounds.
Topics: Acetylcholinesterase; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Female; Insecticides; Isoflurophate; Kinetics; Mathematics; Neurotoxins; Paraoxon; Structure-Activity Relationship | 1983 |
Intramolecular group transfer is a characteristic of neurotoxic esterase and is independent of the tissue source of the enzyme. A comparison of the aging behaviour of di-isopropyl phosphorofluoridate-labelled proteins in brain, spinal cord, liver, kidney
Topics: Animals; Binding Sites; Brain; Carboxylic Ester Hydrolases; Chickens; Female; Humans; Isoflurophate; Kidney; Liver; Paraoxon; Placenta; Protein Conformation; Proteins; Spinal Cord; Spleen; Time Factors; Tissue Distribution | 1983 |
Comparison of atropine and dexetimide in treatment of intoxications by selected organophosphates.
Topics: Animals; Atropine; Dexetimide; Diet; Guinea Pigs; Insecticides; Isoflurophate; Lethal Dose 50; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Piperidines | 1982 |
The use of spinal cord cell cultures in the study of neurotoxicological agents.
Topics: Animals; Cells, Cultured; Glutamates; Isoflurophate; Kainic Acid; Mice; Organophosphorus Compounds; Paraoxon; Pyrrolidines; Sodium Glutamate; Spinal Cord | 1980 |
Test factors affecting the time course of avoidance depression after DFP and paraoxon.
Topics: Animals; Avoidance Learning; Depression, Chemical; Isoflurophate; Male; Paraoxon; Rats; Rats, Inbred Strains; Reinforcement Schedule; Time Factors | 1981 |
Gel-electrophoretic identification of hen brain neurotoxic esterase, labelled with tritiated di-isopropyl phosphorofluoridate.
Topics: Animals; Binding Sites; Brain; Carboxylic Ester Hydrolases; Chickens; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoflurophate; Organophosphorus Compounds; Paraoxon; Peptides; Phosphinic Acids; Tritium | 1981 |
Neurotoxic esterase in human nervous tissue.
Topics: Brain; Esterases; Humans; Isoflurophate; Male; Middle Aged; Neurotoxins; Organ Specificity; Paraoxon; Peripheral Nerves; Spinal Cord | 1980 |
Purification and physical properties of oligomeric and monomeric carboxylesterases from rabbit liver.
Topics: Amino Acids; Animals; Binding Sites; Carbohydrates; Carboxylic Ester Hydrolases; Isoenzymes; Isoflurophate; Kinetics; Liver; Macromolecular Substances; Molecular Weight; Paraoxon; Rabbits | 1980 |
Use of differentiated cholinergic and second messenger endpoints to evaluate cholinesterase inhibitors.
Topics: Acetylcholine; Animals; Cell Line; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Isoflurophate; Mice; Neostigmine; Neurons; Organophosphorus Compounds; Paraoxon; Second Messenger Systems; Septal Nuclei | 1995 |
Separation of two forms of neuropathy target esterase in the soluble fraction of the hen sciatic nerve.
Topics: Animals; Carboxylic Ester Hydrolases; Cell Fractionation; Chickens; Chromatography, Gel; Female; Isoflurophate; Kinetics; Molecular Weight; Paraoxon; Sciatic Nerve; Valerates | 1995 |
Physiologically based pharmacokinetic model for the inhibition of acetylcholinesterase by organophosphate esters.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Environmental Exposure; Humans; Hydrolysis; Isoflurophate; Mice; Models, Biological; Paraoxon; Rats; Reproducibility of Results; Risk Assessment | 1994 |
Raman spectroscopic study of conjugates of butyrylcholinesterase with organophosphates.
Topics: Butyrylcholinesterase; Cholinesterase Inhibitors; Isoflurophate; Organophosphorus Compounds; Paraoxon; Protein Structure, Secondary; Soman; Spectrum Analysis, Raman | 1995 |
Choline derivatives and sodium fluoride protect acetylcholinesterase against irreversible inhibition and aging by DFP and paraoxon.
Topics: Acetylcholinesterase; Choline; Enzymes, Immobilized; Isoflurophate; Paraoxon; Phosphorylation; Sodium Fluoride | 1994 |
Solubilization of neuropathy target esterase and other phenyl valerate carboxylesterases from chicken embryonic brain by phospholipase A2.
Topics: Animals; Bee Venoms; Brain; Carboxylic Ester Hydrolases; Chick Embryo; Enzyme Stability; Hot Temperature; Isoflurophate; Paraoxon; Phospholipases A; Phospholipases A2; Snake Venoms; Substrate Specificity | 1994 |
Partial characterization of neuropathy target esterase and related phenyl valerate esterases from bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Brain; Carboxylic Ester Hydrolases; Cattle; Isoflurophate; Models, Biological; Paraoxon; Subcellular Fractions | 1994 |
Acute and subacute organophosphate poisoning in the rat.
Topics: Animals; Cholinesterase Inhibitors; Fenthion; Insecticides; Isoflurophate; Muscle Fibers, Skeletal; Necrosis; Paraoxon; Rats; Rats, Wistar; Time Factors | 1994 |
Insecticide resistance and malathion carboxylesterase in the sheep blowfly, Lucilia cuprina.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carboxylic Ester Hydrolases; Cell Fractionation; Crosses, Genetic; Diptera; Female; Hydrogen-Ion Concentration; Insecticide Resistance; Isoelectric Point; Isoflurophate; Kinetics; Malathion; Male; Molecular Sequence Data; Molecular Weight; Oligopeptides; Organophosphates; Paraoxon; Physostigmine | 1994 |
Interaction of organophosphorus compounds with muscarinic receptors in SH-SY5Y human neuroblastoma cells.
Topics: Carbachol; Humans; Inositol Phosphates; Insecticides; Isoflurophate; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Receptors, Muscarinic; Second Messenger Systems; Tumor Cells, Cultured | 1994 |
Neuropathology of organophosphate-induced delayed neuropathy (OPIDN) in young chicks.
Topics: Age Factors; Animals; Central Nervous System Diseases; Chickens; Female; Isoflurophate; Microscopy, Electron; Paraoxon; Peripheral Nervous System Diseases; Time Factors | 1994 |
Soluble and particulate organophosphorus neuropathy target esterase in brain and sciatic nerve of the hen, cat, rat, and chick.
Topics: Aging; Animals; Brain; Carboxylic Ester Hydrolases; Cats; Chickens; Cytosol; Female; Isoflurophate; Kinetics; Organ Specificity; Paraoxon; Rats; Rats, Wistar; Sciatic Nerve; Species Specificity; Subcellular Fractions | 1993 |
Avian embryonic brain reaggregate culture system. II. NTE activity discriminates between effects of a single neuropathic or nonneuropathic organophosphorus compound exposure.
Topics: Acetylcholinesterase; Animals; Brain; Carboxylic Ester Hydrolases; Cell Aggregation; Cells, Cultured; Chick Embryo; Culture Techniques; Isoflurophate; NADP; Organophosphorus Compounds; Paraoxon | 1994 |
Computerized analysis of covalent inhibition kinetics for identification of heart muscle cholinesterase and brain carboxylesterase isoenzymes. Design of differential inhibition assays.
Topics: Acetylthiocholine; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Computers; Female; Humans; Hydrolysis; Isoenzymes; Isoflurophate; Kinetics; Least-Squares Analysis; Macaca mulatta; Myocardium; Paraoxon; Swine | 1993 |
Differential effects of triphenylphosphite and diisopropyl phosphorofluoridate on catecholamine secretion from bovine adrenomedullary chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcium; Carboxylic Ester Hydrolases; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Drug Interactions; Isoflurophate; Organophosphorus Compounds; Paraoxon; Phosphites; Potassium | 1993 |
Organophosphorus inhibition and heat inactivation kinetics of particulate and soluble forms of peripheral nerve neuropathy target esterase.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Female; Hot Temperature; Isoenzymes; Isoflurophate; Kinetics; Organophosphorus Compounds; Paraoxon; Sciatic Nerve | 1995 |
Subacute neurotoxicity induced in mice by potent organophosphorus neuropathy target esterase inhibitors.
Topics: Animals; Ataxia; Biomarkers; Brain; Brain Edema; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Enzyme Inhibitors; Isoflurophate; Male; Mice; Organophosphorus Compounds; Paralysis; Paraoxon; Sciatic Nerve; Spinal Cord; Stereoisomerism; Structure-Activity Relationship | 1996 |
Bovine chromaffin cells in culture show carboxylesterase activities sensitive to organophosphorus compounds.
Topics: Animals; Carboxylic Ester Hydrolases; Cattle; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Chromaffin Cells; Isoflurophate; Paraoxon; Valerates | 1996 |
The effects of multiple low doses of organophosphates on target enzymes in brain and diaphragm in the mouse.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Diaphragm; Echothiophate Iodide; Insecticides; Isoflurophate; Male; Mice; Paraoxon | 1997 |
Effects of multiple doses of organophosphates on evoked potentials in mouse diaphragm.
Topics: Action Potentials; Animals; Brain; Cholinesterase Inhibitors; Diaphragm; Echothiophate Iodide; Evoked Potentials; Insecticides; Isoflurophate; Male; Mice; Paraoxon | 1997 |
Bovine chromaffin cells as in vitro model for the study of non-cholinergic toxic effects of organophosphorus compounds.
Topics: Animals; Calcium Channels; Carboxylic Ester Hydrolases; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Dimethylphenylpiperazinium Iodide; Insecticides; Isoflurophate; Paraoxon; Patch-Clamp Techniques; Toxicity Tests | 1997 |
Chromatographic discrimination of soluble neuropathy target esterase isoenzymes and related phenyl valerate esterases from chicken brain, spinal cord, and sciatic nerve.
Topics: Animals; Biomarkers; Brain; Carboxylic Ester Hydrolases; Chickens; Chromatography, Gel; Hydrogen-Ion Concentration; Isoenzymes; Isoflurophate; Paraoxon; Sciatic Nerve; Solubility; Spinal Cord | 1997 |
Augmented hydrolysis of diisopropyl fluorophosphate in engineered mutants of phosphotriesterase.
Topics: Aryldialkylphosphatase; Binding Sites; Crystallography, X-Ray; Escherichia coli; Esterases; Genetic Engineering; Hydrolysis; Isoflurophate; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Organothiophosphorus Compounds; Paraoxon; Phosphoramides; Pseudomonas; Zinc | 1997 |
Discrimination of carboxylesterases of chicken neural tissue by inhibition with a neuropathic, non-neuropathic organophosphorus compounds and neuropathy promoter.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Central Nervous System; Chickens; Cholinesterase Inhibitors; Enzyme Inhibitors; Esterases; Insecticides; Isoflurophate; Nervous System Diseases; Paraoxon; Phenylmethylsulfonyl Fluoride; Sciatic Nerve; Spinal Cord | 1997 |
Different role of carboxylesterases in toxicity and tolerance to paraoxon and DFP.
Topics: Acetylcholinesterase; Animals; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Drug Synergism; Drug Tolerance; Enzyme Inhibitors; Isoflurophate; Kinetics; Lethal Dose 50; Male; Organophosphorus Compounds; Paraoxon; Rats; Rats, Sprague-Dawley | 1999 |
A stable preparation of hen brain neuropathy target esterase for rapid biochemical assessment of neurotoxic potential of organophosphates.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Drug Storage; Enzyme Inhibitors; Enzyme Stability; Female; Freeze Drying; Insecticides; Isoflurophate; Membranes; Organophosphates; Paraoxon | 1999 |
Stability of cytotoxic luteinizing hormone-releasing hormone conjugate (AN-152) containing doxorubicin 14-O-hemiglutarate in mouse and human serum in vitro: implications for the design of preclinical studies.
Topics: Adult; Animals; Antineoplastic Agents; Bombesin; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Drug Interactions; Drug Stability; Gonadotropin-Releasing Hormone; Half-Life; Humans; Hydrolysis; Isoflurophate; Male; Mice; Mice, Nude; Nitrophenols; Paraoxon; Pyrroles; Weight Loss | 2000 |
Degradation of organophosphorous nerve agents by enzyme-polymer nanocomposites: efficient biocatalytic materials for personal protection and large-scale detoxification.
Topics: Adsorption; Aryldialkylphosphatase; Chemical Warfare Agents; Dichlorvos; Enzymes, Immobilized; Esterases; Isoflurophate; Organophosphorus Compounds; Paraoxon; Polymers; Silicones | 2000 |
Mutagenesis of organophosphorus hydrolase to enhance hydrolysis of the nerve agent VX.
Topics: Acetylcholinesterase; Amino Acid Substitution; Aryldialkylphosphatase; Base Sequence; Biodegradation, Environmental; Chemical Warfare Agents; DNA Primers; Esterases; Hydrolysis; Insecticides; Isoflurophate; Mutagenesis, Site-Directed; Organothiophosphates; Organothiophosphorus Compounds; Paraoxon; Parathion; Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester; Recombinant Proteins; Substrate Specificity | 2000 |
Nanocrystalline metal oxides as destructive adsorbents for organophosphorus compounds at ambient temperatures.
Topics: Adsorption; Cholinesterase Inhibitors; Crystallization; Environmental Pollution; Insecticides; Isoflurophate; Magnesium Oxide; Nanotechnology; Organophosphorus Compounds; Paraoxon; Temperature | 2002 |
Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds.
Topics: Calcium; Dose-Response Relationship, Drug; Homeostasis; Humans; Isoflurophate; Neurites; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Tumor Cells, Cultured | 2003 |
Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Cholinesterase Reactivators; Inhibitory Concentration 50; Isoflurophate; Nonlinear Dynamics; Paraoxon | 2003 |
New principle of direct real-time monitoring of the interaction of cholinesterase and its inhibitors by piezolectric biosensor.
Topics: Biosensing Techniques; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrochemistry; Enzymes, Immobilized; Humans; Immunoenzyme Techniques; Insecticides; Isoflurophate; Online Systems; Paraoxon; Reproducibility of Results; Sensitivity and Specificity | 2003 |
[Specific antidote treatment in protracted poisoning with alkylphosphates (paraoxon, parathion, DFP) & eserin in guinea pigs].
Topics: Animals; Antidotes; Dental Care; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Humans; Isoflurophate; Organophosphate Poisoning; Paraoxon; Parathion; Phosphates; Physostigmine | 1957 |
[Inhibition and reactivation of cholinesterases after poisoning with paraoxon and DFP in vitro].
Topics: Cholinesterase Inhibitors; Humans; In Vitro Techniques; Isoflurophate; Paraoxon; Phosphates | 1961 |
Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity.
Topics: Adrenal Medulla; Animals; Carboxylic Ester Hydrolases; Cattle; Chromaffin Cells; Enzyme Inhibitors; Isoflurophate; Neurotoxicity Syndromes; Organophosphorus Compounds; Paraoxon; Toxicity Tests | 2004 |
Neurofilament 200 as an indicator of differences between mipafox and paraoxon sensitivity in Sy5Y neuroblastoma cells.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Insecticides; Isoflurophate; Nerve Growth Factor; Neuroblastoma; Neurofilament Proteins; Paraoxon; Structure-Activity Relationship; Toxicity Tests | 2004 |
Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver.
Topics: Aging; Amino Acid Sequence; Animals; Aryldialkylphosphatase; Calcium; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cell Death; Chlorides; Cobalt; Coumarins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Firefly Luciferin; Hepatocytes; Hydrolysis; Intracellular Signaling Peptides and Proteins; Isoflurophate; Lactones; Liver; Magnesium Chloride; Male; Manganese Compounds; Mice; Mice, Knockout; Molecular Sequence Data; Paraoxon; Protein Binding; Rats; Rats, Wistar; Sequence Homology, Amino Acid; Substrate Specificity; Sulfotransferases | 2004 |
Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Ganglia, Spinal; Humans; Isoflurophate; Microscopy, Confocal; Mitochondria; Multienzyme Complexes; Neuroblastoma; Neurons; Organophosphorus Compounds; Paraoxon; Phenylmethylsulfonyl Fluoride; Schwann Cells; Time Factors | 2005 |
Reduction of neuropathy target esterase does not affect neuronal differentiation, but moderate expression induces neuronal differentiation in human neuroblastoma (SK-N-SH) cell line.
Topics: Acetylcholinesterase; Animals; Antineoplastic Agents; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Line, Tumor; Cholinesterase Inhibitors; Gene Silencing; Humans; Isoflurophate; Neuroblastoma; Neurons; Paraoxon; RNA Interference; Tretinoin | 2005 |
Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH).
Topics: Acetylcholinesterase; Biodegradation, Environmental; Carboxylic Ester Hydrolases; Cell Line, Tumor; Humans; Insecticides; Isoflurophate; Nervous System; Neurites; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Phosphoric Monoester Hydrolases; Toxicity Tests | 2006 |
Comparison of chromaffin cells from several animal sources for their use as an in vitro model to study the mechanism of organophosphorous toxicity.
Topics: Animals; Carboxylic Ester Hydrolases; Cattle; Cells, Cultured; Chromaffin Cells; Goats; Horses; Isoflurophate; Organophosphorus Compounds; Paraoxon; Sheep; Species Specificity; Swine | 2006 |
Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters.
Topics: Acetylcholinesterase; Acetylthiocholine; Animals; Bungarus; Chlorpyrifos; Disulfoton; Echothiophate Iodide; Isoflurophate; Mutagenesis, Site-Directed; Mutation; Organophosphorus Compounds; Paraoxon | 2006 |
Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer.
Topics: Adenoviridae; Animals; Carboxylic Ester Hydrolases; Cattle; Cells, Cultured; Chromaffin Cells; Genetic Vectors; Humans; Isoflurophate; Paraoxon; Transfection; Valerates | 2007 |
Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines.
Topics: Astrocytoma; Blotting, Western; Calcium; Cell Line, Tumor; Cytosol; Endoplasmic Reticulum Chaperone BiP; Esterases; Gene Expression; Gene Expression Profiling; Heat-Shock Proteins; Humans; Isoflurophate; Mitochondria; Molecular Chaperones; Neuroblastoma; Neurotoxicity Syndromes; Oligonucleotide Array Sequence Analysis; Paraoxon | 2007 |
Array biosensor based on enzyme kinetics monitoring by fluorescence spectroscopy: application for neurotoxins detection.
Topics: Biosensing Techniques; Enzyme Stability; Enzymes, Immobilized; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Paraoxon; Parathion; Sensitivity and Specificity; Spectrometry, Fluorescence; Titanium | 2007 |
The role and characterization of phospholipase A1 in mediating lysophosphatidylcholine synthesis in Trypanosoma brucei.
Topics: Animals; Cations, Divalent; Isoflurophate; Kinetics; Lysophosphatidylcholines; Mice; Paraoxon; Phenylmethylsulfonyl Fluoride; Phospholipases A; Phospholipases A1; Spectrometry, Mass, Electrospray Ionization; Trypanosoma brucei brucei; Trypanosomiasis, African | 2007 |
Molecular cloning and expression of the C-terminal domain of mouse NTE-related esterase.
Topics: Animals; Blotting, Western; Carboxylic Ester Hydrolases; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Gene Expression Regulation, Enzymologic; Isoflurophate; Membrane Proteins; Mice; Paraoxon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Valerates | 2007 |
Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Enzyme Reactivators; Isoflurophate; Oximes; Paraoxon; Pyridinium Compounds | 2008 |
Fullerene antioxidants decrease organophosphate-induced acetylcholinesterase inhibition in vitro.
Topics: Acetylcholinesterase; Animals; Antioxidants; Brain; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chickens; Cholinesterase Inhibitors; Cholinesterase Reactivators; Embryo, Mammalian; Fullerenes; Humans; Isoflurophate; Mice; Neuroblastoma; Neurons; Organophosphates; Paraoxon; Superoxides | 2011 |
Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Interactions; Enzyme Induction; Isoflurophate; Kinetics; Neurotoxicity Syndromes; Organophosphorus Compounds; Paraoxon | 2011 |
Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry.
Topics: Alkynes; Blood Chemical Analysis; Chromatography, Liquid; Drug Stability; Enzyme Inhibitors; Esterases; Humans; Hydrolysis; Isoflurophate; Models, Chemical; Paraoxon; Phenylmethylsulfonyl Fluoride; Physostigmine; Purine Nucleosides; Tandem Mass Spectrometry; Thenoyltrifluoroacetone | 2012 |
Characterization of status epilepticus induced by two organophosphates in rats.
Topics: Animals; Anticonvulsants; Atropine; Brain; Diazepam; Electroencephalography; Isoflurophate; Male; Neurons; Paraoxon; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2012 |
Interactions of neuropathy inducers and potentiators/promoters with soluble esterases.
Topics: Animals; Brain; Catalytic Domain; Chickens; Enzyme Inhibitors; Esterases; Isoflurophate; Kinetics; Nervous System Diseases; Organophosphorus Compounds; Paraoxon; Phenylmethylsulfonyl Fluoride; Sciatic Nerve; Solubility | 2013 |
In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes.
Topics: Acetylcholinesterase; Alkenes; Animals; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Electrophorus; Isoflurophate; Kinetics; Obidoxime Chloride; Paraoxon; Pyridinium Compounds; Structure-Activity Relationship; Trimedoxime | 2014 |
Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox.
Topics: Chromatin Assembly and Disassembly; Embryonal Carcinoma Stem Cells; Genome, Human; Histones; Humans; Insecticides; Isoflurophate; Neurogenesis; Neurons; Nucleosomes; Paraoxon; Phenotype; Tretinoin | 2014 |
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches.
Topics: Acetylcholinesterase; Amino Acid Sequence; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Isoflurophate; Kinetics; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Oximes; Paraoxon; Phosphorylation; Protein Conformation; Sarin; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells.
Topics: Animals; Biomarkers; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Survival; Chlorpyrifos; Gene Expression Regulation, Developmental; Gene Silencing; Isoflurophate; Mice; Mouse Embryonic Stem Cells; Paraoxon | 2016 |
High concentration of trichlorfon (1mM) disrupts axonal cytoskeleton and decreases the expression of plasticity-related proteins in SH-SY5Y cells.
Topics: Acetylcholinesterase; Axons; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cholinesterase Inhibitors; Cytoskeleton; GAP-43 Protein; Humans; Insecticides; Isoflurophate; L-Lactate Dehydrogenase; Neuronal Plasticity; Paraoxon; Synapsins; Trichlorfon | 2017 |
Hydrolyzing activities of phenyl valerate sensitive to organophosphorus compounds paraoxon and mipafox in human neuroblastoma SH-SY5Y cells.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrolysis; Isoflurophate; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Valerates | 2018 |
Determination of camostat and its metabolites in human plasma - Preservation of samples and quantification by a validated UHPLC-MS/MS method.
Topics: Blood Specimen Collection; Chromatography, High Pressure Liquid; COVID-19; COVID-19 Drug Treatment; Enzyme Inhibitors; Esterases; Esters; Guanidines; Humans; Hydrolysis; Isoflurophate; Paraoxon; Reproducibility of Results; SARS-CoV-2; Tandem Mass Spectrometry | 2021 |