isoflurophate has been researched along with mipafox in 101 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 27 (26.73) | 18.7374 |
1990's | 39 (38.61) | 18.2507 |
2000's | 21 (20.79) | 29.6817 |
2010's | 14 (13.86) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Fang, SC; Freed, VH; Kar, PP; Matin, MA | 1 |
Carboni, D; Dyer, K; Ehrich, M; Jortner, BS | 1 |
Dyer, KR; Ehrich, M; Jortner, BS; Shell, LG | 1 |
Barril, J; Carrera, V; Mauricio, M; Pellín, M; Vilanova, E | 1 |
Chemnitius, GC; Chemnitius, JM; Haselmeyer, KH; Kreuzer, H; Zech, R | 1 |
Husain, K | 1 |
Fryer, GC | 1 |
Capodicasa, E; Lotti, M; Moretto, A; Peraica, M | 1 |
Padilla, S; Pope, CN | 1 |
Hussain, K; Matin, MA | 1 |
Ishikawa, Y; McNamee, MG; Thomas, TC; Wilson, BW | 1 |
Hernández, AF; Pla, A; Villanueva, E | 1 |
Johnson, MK | 1 |
Barril, JB; Pellin, MC; Vilanova, E | 1 |
Novak, R; Padilla, S | 1 |
Lyerly, D; Padilla, S; Veronesi, B | 1 |
Goss, LB; Moore, MT; Reveley, JW; Sabourin, TD | 1 |
Abou-Donia, MB; Carrington, CD | 3 |
Becker, CE; Lotti, M; Spear, RC; Wei, ET | 1 |
Hoskin, FC | 1 |
Padilla, S; Veronesi, B | 1 |
Dettbarn, WD; Gupta, RC; Patterson, GT | 1 |
Metcalf, RL | 1 |
Chow, E; Ishikawa, Y; McChesney, M; McNamee, MG; Wilson, BW | 1 |
Chow, E; Cisson, CM; Ishikawa, Y; Wilson, BW | 1 |
Chemnitius, JM; Zech, R | 1 |
Williams, DG | 1 |
Johnson, MK; Williams, DG | 1 |
Ahmed, NS; Curely, A; El-Sebae, AE; Soliman, SA | 1 |
Barril, J; Escudero, MA; Tormo, N; Vilanova, E | 1 |
Das Gupta, S; Husain, K; Pant, SC; Raza, SK; Singh, R | 1 |
Seifert, J; Wilson, BW | 1 |
Casida, JE; Wu, SY; Yoshida, M | 1 |
Blain, PG; Kelly, SS; Mutch, E; Williams, FM | 2 |
Reig, JA; Sogorb, MA; Vilanova, E; Viniegra, S | 1 |
De Bleecker, J; De Reuck, J; Lison, D; Van Den Abeele, K; Willems, J | 1 |
Costa, LG; Ehrich, M; Intropido, L | 1 |
Carrera, V; Díaz-Alejo, N; Sogorb, MA; Vicedo, JL; Vilanova, E | 1 |
Díaz-Alejo, N; Gimeno, JR; Sogorb, MA; Tormo, N; Vilanova, E | 1 |
Ehrich, M; Nostrandt, AC | 1 |
Chemnitius, JM; Dewald, K; Kreuzer, H; Zech, R | 1 |
Johnson, MK; Milatovic, D | 1 |
Barril, J; Diaz-Alejo, N; Tormo, N; Vilanova, E | 1 |
Casida, JE; Wu, SY | 1 |
Hammock, BD; Mackay, CE; Wilson, BW | 1 |
Quintanar, JL; Sogorb, MA; Vilanova, E; Viniegra, S | 1 |
Blain, PG; Charlton, C; de Blaquière, GE; Kelly, SS; Mutch, E; Williams, FM | 1 |
Blain, PG; de Blaquière, GE; Kelly, SS; Williams, FM | 2 |
Bas, S; Gutiérrez, LM; Sogorb, MA; Vilanova, E; Viniegra, S | 1 |
Céspedes, MV; Escudero, MA; Vilanova, E | 1 |
Chemnitius, JM; Gonska, BD; Haselmeyer, KH; Kreuzer, H; Zech, R | 1 |
Harp, P; Pope, CN; Tanaka, D | 1 |
Lotti, M; Milatovic, D; Moretto, A; Osman, KA | 1 |
Barril, J; Céspedes, MV; Escudero, MA; Sogorb, MA; Vicedo, JL; Vilanova, E | 1 |
Casida, JE; Li, W | 1 |
Chemnitius, JM; Sadowski, R; Winkel, H; Zech, R | 1 |
Makhaeva, GF; Malygin, VV | 1 |
Casida, JE; Kamijima, M | 1 |
Barhoumi, R; Burghardt, RC; Donnelly, KC; Hong, MS; Hong, SJ; Tiffany-Castiglioni, E; Venkatraj, V; Wild, JR | 1 |
Barril, J; Estévez, J; Garcia-Pérez, AG; Vilanova, E | 1 |
Kropp, TJ; Richardson, RJ | 3 |
Donnelly, KC; Mumtaz, MM; Tang, Y; Tiffany-Castiglioni, E | 1 |
BECKETT, AG; BIDSTRUP, PL; BONNELL, JA | 1 |
CUTHBERT, AW | 1 |
BROWNLEE, G; JOHNSON, ES | 1 |
KARNOVSKY, ML; MAJNO, G | 1 |
Glynn, P; Kropp, TJ; Richardson, RJ | 1 |
Casida, JE; Quistad, GB | 1 |
Carrera, V; Quesada, E; Sogorb, MA; Vilanova, E | 1 |
Barril, J; Estévez, J; García-Pérez, AG; Pellín, M; Vilanova, E | 1 |
Cho, T; Tiffany-Castiglioni, E | 1 |
Ehrich, M; Jortner, BS; Knight, K; Massicotte, C; Van der Schyf, CJ | 1 |
Chang, PA; Chen, R; Wu, YJ | 1 |
Cho, TM; Donnelly, KC; Tiffany-Castiglioni, E; Wild, JR | 1 |
Carrera, V; García-Fernández, AJ; Quesada, E; Romero, D; Sogorb, MA; Vilanova, E | 1 |
Carrera, V; Quesada, E; Sabater, E; Sogorb, MA; Vilanova, E | 1 |
Carrera, V; Castell, JV; Quesada, E; Vilanova, E | 1 |
Lotti, M; Moretto, A; Nicolli, A | 1 |
Eremenko, AV; Kurochkin, IN; Makhaeva, GF; Malygin, VV; Richardson, RJ; Sigolaeva, LV; Sokolovskaya, LG; Strakhova, NN | 1 |
Chang, PA; Long, DX; Wu, YJ | 2 |
Fink, JK; Hein, ND; Rainier, SR; Richardson, RJ; Stuckey, JA | 1 |
Estévez, J; Mangas, I; Vilanova, E | 2 |
Estévez, J; Mangas, I; Sogorb, MÁ; Vilanova, E | 1 |
Benabent, M; Estévez, J; Mangas, I; Vilanova, E | 1 |
Bal-Price, A; Collotta, A; Fabbri, M; Gribaldo, L; Harris, G; Pamies, D; Scelfo, B; Sogorb, MA; Vilanova, E | 1 |
Benabent, M; Estévez, J; Mangas, I; Sogorb, MÁ; Vilanova, E | 1 |
Estévez, J; França, TC; Komives, E; Mangas, I; Radić, Z; Taylor, P; Vilanova, E | 1 |
Candela, H; Estévez, J; Ghassemian, M; Mangas, I; Radić, Z; Taylor, P; Vilanova, E | 1 |
Del Río, E; Estévez, J; Fuster, E; Sogorb, MA; Vilanova, E | 1 |
Emerick, GL; Fernandes, LS; Ferreira, RS; Santos, ACD; Santos, NAGD | 1 |
Dos Santos, NAG; Emerick, GL; Fernandes, LS; Santos, ACD | 1 |
Dos Santos, AC; Dos Santos, NAG; Emerick, GL; Fernandes, LS | 1 |
Del Río, E; Estévez, J; González-González, M; Sogorb, MA; Vilanova, E | 1 |
101 other study(ies) available for isoflurophate and mipafox
Article | Year |
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Role of striatal dopamine in delayed neurotoxic effects of organophosphorus compounds.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Corpus Striatum; Fenitrothion; Isoflurophate; Leptophos; Male; Motor Skills; Organophosphorus Compounds; Propylamines; Rats | 1976 |
Comparative evolution of mipafox-induced delayed neuropathy in rats and hens.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Disease Models, Animal; Female; Isoflurophate; Male; Nervous System Diseases; Rats; Species Specificity | 1992 |
Comparative dose-response studies of organophosphorus ester-induced delayed neuropathy in rats and hens administered mipafox.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Isoflurophate; Male; Microscopy, Electron; Nervous System Diseases; Rats; Species Specificity | 1992 |
Local application of neuropathic organophosphorus compounds to hen sciatic nerve: inhibition of neuropathy target esterase and peripheral neurological impairments.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Female; Isoflurophate; Locomotion; Peripheral Nerves; Peroneal Nerve; Sciatic Nerve | 1992 |
Cholinesterases of heart muscle. Characterization of multiple enzymes using kinetics of irreversible organophosphorus inhibition.
Topics: Acetylthiocholine; Animals; Butyrylthiocholine; Cholinesterase Inhibitors; Cholinesterases; Female; Heart Ventricles; Isoflurophate; Kinetics; Male; Myocardium; Paraoxon; Swine | 1992 |
Peripheral biochemical marker for organophosphate-induced delayed neurotoxicity.
Topics: Animals; Blood Platelets; Brain; Carboxylic Ester Hydrolases; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoflurophate; Mice | 1991 |
Dementing disease in a married couple.
Topics: Adult; Alzheimer Disease; Female; Humans; Isoflurophate; Occupational Diseases; Poisoning | 1991 |
Age sensitivity to organophosphate-induced delayed polyneuropathy. Biochemical and toxicological studies in developing chicks.
Topics: Age Factors; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Dichlorvos; Isoflurophate; Paraoxon; Peripheral Nerves; Spinal Cord | 1991 |
Potentiation of organophosphorus-induced delayed neurotoxicity by phenylmethylsulfonyl fluoride.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Synergism; Female; Isoflurophate; Nervous System; Phenylmethylsulfonyl Fluoride; Sciatic Nerve; Spinal Cord | 1990 |
Striatal neurochemical changes and motor dysfunction in mipafox-treated animals.
Topics: Acetylcholinesterase; Animals; Carboxylic Ester Hydrolases; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Isoflurophate; Male; Movement Disorders; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1985 |
Correlation of neuropathy target esterase activity with specific tritiated di-isopropyl phosphorofluoridate-labelled proteins.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Centrifugation, Density Gradient; Chick Embryo; Isoflurophate; Membrane Proteins; Microsomes; Paraoxon | 1989 |
Lack of inhibition of glycolytic enzymes by the neurotoxic organophosphorus compounds mipafox and methamidofos.
Topics: Animals; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Hexokinase; Insecticides; Isoflurophate; L-Lactate Dehydrogenase; Organophosphorus Compounds; Organothiophosphorus Compounds; Phosphofructokinase-1 | 1988 |
Sensitivity and selectivity of compounds interacting with neuropathy target esterase. Further structure-activity studies.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Isoflurophate; Paraoxon; Structure-Activity Relationship; Substrate Specificity | 1988 |
Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Female; Isoflurophate; Nerve Regeneration; Organophosphorus Compounds; Paraoxon; Sciatic Nerve; Sulfones | 1988 |
An in vitro comparison of rat and chicken brain neurotoxic esterase.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Hydrogen-Ion Concentration; In Vitro Techniques; Isoflurophate; Male; Molecular Weight; Organophosphorus Compounds; Paraoxon; Rats; Species Specificity; Tritium | 1986 |
The correlation between neurotoxic esterase inhibition and mipafox-induced neuropathic damage in rats.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Isoflurophate; Male; Microscopy, Electron; Rats; Spinal Cord; Spinal Cord Diseases | 1986 |
Distribution of neurotoxic esterase activity in the brain of control and diisopropyl phosphorofluoridate-treated hens: in vivo and in vitro exposure.
Topics: Animals; Atropine; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Interactions; Female; Hydrolysis; Injections, Subcutaneous; Isoflurophate; Paraoxon; Physostigmine | 1986 |
Kinetics of substrate hydrolysis and inhibition by mipafox of paraoxon-preinhibited hen brain esterase activity.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Cell Membrane; Chickens; Female; Hydrolysis; Isoflurophate; Kinetics; Models, Chemical; Paraoxon; Phenylacetates; Valerates | 1986 |
Neurotoxic esterase in rooster testis.
Topics: Animals; Ataxia; Brain; Carboxylic Ester Hydrolases; Chickens; Isoflurophate; Male; Organophosphorus Compounds; Paraoxon; Testis; Testosterone | 1985 |
Inhibition of a soman- and diisopropyl phosphorofluoridate (DFP)-detoxifying enzyme by Mipafox.
Topics: Animals; Esterases; Humans; Hydrolases; Hydrolysis; Isoflurophate; Organophosphorus Compounds; Phosphoric Triester Hydrolases; Soman | 1985 |
Characterization of [3H]di-isopropyl phosphorofluoridate-binding proteins in hen brain. Rates of phosphorylation and sensitivity to neurotoxic and non-neurotoxic organophosphorus compounds.
Topics: Animals; Brain; Chickens; Electrophoresis, Polyacrylamide Gel; Female; Isoflurophate; Membrane Proteins; Paraoxon; Phenylmethylsulfonyl Fluoride; Phosphorylation; Proteins | 1985 |
Paraoxon reversibly inhibits neurotoxic esterase.
Topics: Animals; Binding, Competitive; Carboxylic Ester Hydrolases; Catalysis; Chickens; Female; Isoenzymes; Isoflurophate; Paraoxon | 1985 |
Phenylmethylsulfonyl fluoride protects rats from Mipafox-induced delayed neuropathy.
Topics: Animals; Brain; Injections, Intraperitoneal; Injections, Subcutaneous; Isoflurophate; Male; Nervous System Diseases; Phenylmethylsulfonyl Fluoride; Rats; Spinal Cord; Sulfones | 1985 |
Mechanisms involved in the development of tolerance to DFP toxicity.
Topics: Acetylcholinesterase; Animals; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Tolerance; Isoflurophate; Male; Muscles; Necrosis; Rats; Rats, Inbred Strains; Tetraisopropylpyrophosphamide | 1985 |
Historical perspective of organophosphorus ester-induced delayed neurotoxicity.
Topics: Animals; Ataxia; Carboxylic Ester Hydrolases; Chickens; Drug Contamination; Humans; Insecticides; Isoflurophate; Leptophos; Nervous System; Structure-Activity Relationship | 1982 |
Separation of paraoxon and mipafox sensitive esterases by sucrose density gradient sedimentation.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Centrifugation, Density Gradient; Chick Embryo; Chickens; Isoflurophate; Paraoxon; Spinal Cord | 1983 |
Multilevel studies of organophosphate toxicity.
Topics: Acetylcholinesterase; Animals; Carboxylic Ester Hydrolases; Cells, Cultured; Coturnix; Isoflurophate; Muscles; Nervous System Diseases; Paraoxon; Tissue Distribution | 1983 |
Inhibition of brain carboxylesterases by neurotoxic and nonneurotoxic organophosphorus compounds.
Topics: Acetylcholinesterase; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Female; Insecticides; Isoflurophate; Kinetics; Mathematics; Neurotoxins; Paraoxon; Structure-Activity Relationship | 1983 |
Intramolecular group transfer is a characteristic of neurotoxic esterase and is independent of the tissue source of the enzyme. A comparison of the aging behaviour of di-isopropyl phosphorofluoridate-labelled proteins in brain, spinal cord, liver, kidney
Topics: Animals; Binding Sites; Brain; Carboxylic Ester Hydrolases; Chickens; Female; Humans; Isoflurophate; Kidney; Liver; Paraoxon; Placenta; Protein Conformation; Proteins; Spinal Cord; Spleen; Time Factors; Tissue Distribution | 1983 |
Gel-electrophoretic identification of hen brain neurotoxic esterase, labelled with tritiated di-isopropyl phosphorofluoridate.
Topics: Animals; Binding Sites; Brain; Carboxylic Ester Hydrolases; Chickens; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isoflurophate; Organophosphorus Compounds; Paraoxon; Peptides; Phosphinic Acids; Tritium | 1981 |
Subcellular distribution of neurotoxic esterase activity in lamb and mouse brain.
Topics: Animals; Brain; Cell Fractionation; Cell Nucleus; Esterases; Isoflurophate; Mice; Microsomes; Mitochondria; Neurotoxins; Sheep; Solubility; Species Specificity | 1980 |
Separation of two forms of neuropathy target esterase in the soluble fraction of the hen sciatic nerve.
Topics: Animals; Carboxylic Ester Hydrolases; Cell Fractionation; Chickens; Chromatography, Gel; Female; Isoflurophate; Kinetics; Molecular Weight; Paraoxon; Sciatic Nerve; Valerates | 1995 |
A comparative study of delayed neurotoxicity in hens following repeated administration of organophosphorus compounds.
Topics: Animals; Ataxia; Blood Platelets; Brain; Carboxylic Ester Hydrolases; Central Nervous System; Chickens; Cholinesterase Inhibitors; Female; Isoflurophate; Parathion; Sarin; Spinal Cord; Structure-Activity Relationship | 1995 |
Solubilization of neuropathy target esterase and other phenyl valerate carboxylesterases from chicken embryonic brain by phospholipase A2.
Topics: Animals; Bee Venoms; Brain; Carboxylic Ester Hydrolases; Chick Embryo; Enzyme Stability; Hot Temperature; Isoflurophate; Paraoxon; Phospholipases A; Phospholipases A2; Snake Venoms; Substrate Specificity | 1994 |
Reactivity and stereospecificity of neuropathy target esterase and alpha-chymotrypsin with 2-substituted-4H-1,3,2-benzodioxaphosphorin 2-oxides.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Chymotrypsin; Female; Isoflurophate; Nervous System Diseases; Organophosphorus Compounds; Stereoisomerism; Time Factors; Toxicity Tests | 1994 |
Electrophysiological and biochemical effects following single doses of organophosphates in the mouse.
Topics: Acetylcholinesterase; Action Potentials; Animals; Brain; Carboxylic Ester Hydrolases; Echothiophate Iodide; Evoked Potentials; In Vitro Techniques; Isoflurophate; Male; Mice; Neuromuscular Junction | 1994 |
Partial characterization of neuropathy target esterase and related phenyl valerate esterases from bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Brain; Carboxylic Ester Hydrolases; Cattle; Isoflurophate; Models, Biological; Paraoxon; Subcellular Fractions | 1994 |
Acute and subacute organophosphate poisoning in the rat.
Topics: Animals; Cholinesterase Inhibitors; Fenthion; Insecticides; Isoflurophate; Muscle Fibers, Skeletal; Necrosis; Paraoxon; Rats; Rats, Wistar; Time Factors | 1994 |
Interaction of organophosphorus compounds with muscarinic receptors in SH-SY5Y human neuroblastoma cells.
Topics: Carbachol; Humans; Inositol Phosphates; Insecticides; Isoflurophate; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Receptors, Muscarinic; Second Messenger Systems; Tumor Cells, Cultured | 1994 |
In vivo inhibition by mipafox of soluble and particulate forms of organophosphorus neuropathy target esterase (NTE) in hen sciatic nerve.
Topics: Animals; Ataxia; Carboxylic Ester Hydrolases; Chickens; Female; Isoflurophate; Reflex; Sciatic Nerve; Solubility | 1994 |
Soluble and particulate organophosphorus neuropathy target esterase in brain and sciatic nerve of the hen, cat, rat, and chick.
Topics: Aging; Animals; Brain; Carboxylic Ester Hydrolases; Cats; Chickens; Cytosol; Female; Isoflurophate; Kinetics; Organ Specificity; Paraoxon; Rats; Rats, Wistar; Sciatic Nerve; Species Specificity; Subcellular Fractions | 1993 |
Modification of mipafox-induced inhibition of neuropathy target esterase in neuroblastoma cells of human origin.
Topics: Aldicarb; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Humans; Isoflurophate; Nerve Growth Factors; Neuroblastoma; Tumor Cells, Cultured; Verapamil | 1993 |
Computerized analysis of covalent inhibition kinetics for identification of heart muscle cholinesterase and brain carboxylesterase isoenzymes. Design of differential inhibition assays.
Topics: Acetylthiocholine; Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Computers; Female; Humans; Hydrolysis; Isoenzymes; Isoflurophate; Kinetics; Least-Squares Analysis; Macaca mulatta; Myocardium; Paraoxon; Swine | 1993 |
Reactivation of phosphorodiamidated acetylcholinesterase and neuropathy target esterase by treatment of inhibited enzyme with potassium fluoride.
Topics: Acetylcholinesterase; Animals; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Fluorides; Isoflurophate; Organophosphorus Compounds; Potassium; Potassium Compounds | 1993 |
Comparative studies of two organophosphorus compounds in the mouse.
Topics: Analysis of Variance; Animals; Biomarkers; Brain; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Diaphragm; Dose-Response Relationship, Drug; Echothiophate Iodide; In Vitro Techniques; Isoflurophate; Male; Mice; Regression Analysis | 1995 |
Organophosphorus inhibition and heat inactivation kinetics of particulate and soluble forms of peripheral nerve neuropathy target esterase.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Female; Hot Temperature; Isoenzymes; Isoflurophate; Kinetics; Organophosphorus Compounds; Paraoxon; Sciatic Nerve | 1995 |
Subacute neurotoxicity induced in mice by potent organophosphorus neuropathy target esterase inhibitors.
Topics: Animals; Ataxia; Biomarkers; Brain; Brain Edema; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Enzyme Inhibitors; Isoflurophate; Male; Mice; Organophosphorus Compounds; Paralysis; Paraoxon; Sciatic Nerve; Spinal Cord; Stereoisomerism; Structure-Activity Relationship | 1996 |
Identification and isolation of a 155-kDa protein with neuropathy target esterase activity.
Topics: Animals; Carboxylic Ester Hydrolases; Chick Embryo; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Isoflurophate; Proteins | 1996 |
Bovine chromaffin cells in culture show carboxylesterase activities sensitive to organophosphorus compounds.
Topics: Animals; Carboxylic Ester Hydrolases; Cattle; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Chromaffin Cells; Isoflurophate; Paraoxon; Valerates | 1996 |
The effects of multiple low doses of organophosphates on target enzymes in brain and diaphragm in the mouse.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Diaphragm; Echothiophate Iodide; Insecticides; Isoflurophate; Male; Mice; Paraoxon | 1997 |
Effects of multiple doses of organophosphates on evoked potentials in mouse diaphragm.
Topics: Action Potentials; Animals; Brain; Cholinesterase Inhibitors; Diaphragm; Echothiophate Iodide; Evoked Potentials; Insecticides; Isoflurophate; Male; Mice; Paraoxon | 1997 |
Bovine chromaffin cells as in vitro model for the study of non-cholinergic toxic effects of organophosphorus compounds.
Topics: Animals; Calcium Channels; Carboxylic Ester Hydrolases; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Dimethylphenylpiperazinium Iodide; Insecticides; Isoflurophate; Paraoxon; Patch-Clamp Techniques; Toxicity Tests | 1997 |
Chromatographic discrimination of soluble neuropathy target esterase isoenzymes and related phenyl valerate esterases from chicken brain, spinal cord, and sciatic nerve.
Topics: Animals; Biomarkers; Brain; Carboxylic Ester Hydrolases; Chickens; Chromatography, Gel; Hydrogen-Ion Concentration; Isoenzymes; Isoflurophate; Paraoxon; Sciatic Nerve; Solubility; Spinal Cord | 1997 |
Mipafox differential inhibition assay for heart muscle cholinesterases: substrate specificity and inhibition of three isoenzymes by physostigmine and quinidine.
Topics: Animals; Cholinesterase Inhibitors; Erythrocytes; Female; Heart; Heart Ventricles; Isoenzymes; Isoflurophate; Male; Myocardium; Physostigmine; Quinidine; Swine | 1997 |
Potentiation of organophosphorus-induced delayed neurotoxicity following phenyl saligenin phosphate exposures in 2-, 5-, and 8-week-old chickens.
Topics: Age Factors; Animals; Axons; Carboxylic Ester Hydrolases; Chickens; Drug Synergism; Enzyme Inhibitors; Female; Isoflurophate; Organophosphorus Compounds; Peripheral Nervous System Diseases; Phenylmethylsulfonyl Fluoride; Spinal Cord | 1997 |
Phenyl valerate esterases other than neuropathy target esterase and the promotion of organophosphate polyneuropathy.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Enzyme Inhibitors; Female; Isoflurophate; Kinetics; Nervous System Diseases; Organophosphorus Compounds; Phenylmethylsulfonyl Fluoride; Sciatic Nerve | 1997 |
Discrimination of carboxylesterases of chicken neural tissue by inhibition with a neuropathic, non-neuropathic organophosphorus compounds and neuropathy promoter.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Central Nervous System; Chickens; Cholinesterase Inhibitors; Enzyme Inhibitors; Esterases; Insecticides; Isoflurophate; Nervous System Diseases; Paraoxon; Phenylmethylsulfonyl Fluoride; Sciatic Nerve; Spinal Cord | 1997 |
A comparison of the electrophysiological effects of two organophosphates, mipafox and ecothiopate, on mouse limb muscles.
Topics: Acetylcholinesterase; Action Potentials; Animals; Cholinesterase Inhibitors; Echothiophate Iodide; Electric Stimulation; Hindlimb; Injections, Subcutaneous; Isoflurophate; Male; Mice; Muscle, Skeletal | 1998 |
Organophosphorus neuropathy target esterase inhibitors selectively block outgrowth of neurite-like and cell processes in cultured cells.
Topics: Acetylcholinesterase; Animals; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Survival; Chlorpyrifos; Cholinesterase Inhibitors; Enzyme Inhibitors; Isoflurophate; Neurites; Organophosphorus Compounds; Sensitivity and Specificity; Tritolyl Phosphates; Tumor Cells, Cultured | 1998 |
Organophosphate inhibition of human heart muscle cholinesterase isoenzymes.
Topics: Acetylthiocholine; Adult; Aged; Aged, 80 and over; Animals; Butyrylthiocholine; Cholinesterase Inhibitors; Cholinesterases; Female; Heart Ventricles; Humans; Isoenzymes; Isoflurophate; Male; Middle Aged; Myocardium; Organophosphates; Swine; Thiocholine | 1999 |
A stable preparation of hen brain neuropathy target esterase for rapid biochemical assessment of neurotoxic potential of organophosphates.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Drug Storage; Enzyme Inhibitors; Enzyme Stability; Female; Freeze Drying; Insecticides; Isoflurophate; Membranes; Organophosphates; Paraoxon | 1999 |
Localization of [3H]octylphosphonyl-labeled neuropathy target esterase by chicken nervous tissue autoradiography.
Topics: Animals; Autoradiography; Carboxylic Ester Hydrolases; Cerebral Cortex; Chickens; Ganglia, Spinal; Isoflurophate; Nerve Tissue; Organophosphorus Compounds; Spinal Cord; Superior Colliculi; Tissue Distribution; Tritium | 1999 |
Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds.
Topics: Calcium; Dose-Response Relationship, Drug; Homeostasis; Humans; Isoflurophate; Neurites; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Tumor Cells, Cultured | 2003 |
Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Cholinesterase Reactivators; Inhibitory Concentration 50; Isoflurophate; Nonlinear Dynamics; Paraoxon | 2003 |
Relative inhibitory potencies of chlorpyrifos oxon, chlorpyrifos methyl oxon, and mipafox for acetylcholinesterase versus neuropathy target esterase.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Cells, Cultured; Chickens; Chlorpyrifos; Cholinesterase Inhibitors; Female; Insecticides; Isoflurophate; Kinetics; Lethal Dose 50; Linear Models | 2003 |
Neurotoxicity of polycyclic aromatic hydrocarbons and simple chemical mixtures.
Topics: Amino Acids; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Glioma; Humans; Isoflurophate; Neuroblastoma; Neuroglia; Neurons; Polycyclic Aromatic Hydrocarbons; Protein Biosynthesis; Rats; Sensitivity and Specificity; Tumor Cells, Cultured | 2003 |
Paralysis following poisoning by a new organic phosphorus insecticide (mipafox); report on two cases.
Topics: Humans; Insecticides; Isoflurophate; Paralysis; Phosphorus | 1953 |
Actions of some anticholinesterases on the smooth muscle of the chick amnion.
Topics: Acetylcholine; Amnion; Animals; Chickens; Cholinesterase Inhibitors; Isoflurophate; Muscle, Smooth; Muscles; Neostigmine; Physostigmine | 1962 |
THE SITE OF THE 5-HYDROXYTRYPTAMINE RECEPTOR ON THE INTRAMURAL NERVOUS PLEXUS OF THE GUINEA-PIG ISOLATED ILEUM.
Topics: Acetylcholine; Animals; Autonomic Nervous System; Choline; Ganglia; Ganglia, Autonomic; Ganglionic Blockers; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; Isoflurophate; Lysergic Acid Diethylamide; Mecamylamine; Muscle, Smooth; Nicotine; Organophosphate Poisoning; Pempidine; Pentolinium Tartrate; Pharmacology; Phenoxybenzamine; Phosphorus; Poisons; Procaine; Receptors, Serotonin; Research; Scopolamine; Serotonin | 1963 |
A biochemical and morphologic study of myelination and demyelination. III. Effect of an organo-phosphorus compound (Mipafox) on the biosynthesis of lipid by nervous tissue of rats and hens.
Topics: Animals; Chickens; Demyelinating Diseases; Female; Isoflurophate; Lipid Metabolism; Lipids; Nerve Tissue; Nervous System; Phosphates; Rats | 1961 |
The mipafox-inhibited catalytic domain of human neuropathy target esterase ages by reversible proton loss.
Topics: Amino Acid Sequence; Carboxylic Ester Hydrolases; Catalytic Domain; Enzyme Inhibitors; Enzyme Reactivators; Humans; Isoflurophate; Kinetics; Molecular Sequence Data; Nerve Degeneration; Organophosphorus Compounds; Phosphatidylcholines; Protons; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
Lysophospholipase inhibition by organophosphorus toxicants.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Humans; Isoflurophate; Liver; Lysophospholipase; Male; Mice; Organophosphorus Compounds | 2004 |
Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity.
Topics: Adrenal Medulla; Animals; Carboxylic Ester Hydrolases; Cattle; Chromaffin Cells; Enzyme Inhibitors; Isoflurophate; Neurotoxicity Syndromes; Organophosphorus Compounds; Paraoxon; Toxicity Tests | 2004 |
The inhibition of the high sensitive peripheral nerve soluble esterases by mipafox. A new mathematical processing for the kinetics of inhibition of esterases by organophosphorus compounds.
Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Chromatography, Gel; Enzyme Inhibitors; Isoflurophate; Models, Biological; Organophosphorus Compounds; Sciatic Nerve | 2004 |
Neurofilament 200 as an indicator of differences between mipafox and paraoxon sensitivity in Sy5Y neuroblastoma cells.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Insecticides; Isoflurophate; Nerve Growth Factor; Neuroblastoma; Neurofilament Proteins; Paraoxon; Structure-Activity Relationship; Toxicity Tests | 2004 |
Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Ganglia, Spinal; Humans; Isoflurophate; Microscopy, Confocal; Mitochondria; Multienzyme Complexes; Neuroblastoma; Neurons; Organophosphorus Compounds; Paraoxon; Phenylmethylsulfonyl Fluoride; Schwann Cells; Time Factors | 2005 |
Reduction of neuropathy target esterase does not affect neuronal differentiation, but moderate expression induces neuronal differentiation in human neuroblastoma (SK-N-SH) cell line.
Topics: Acetylcholinesterase; Animals; Antineoplastic Agents; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Line, Tumor; Cholinesterase Inhibitors; Gene Silencing; Humans; Isoflurophate; Neuroblastoma; Neurons; Paraoxon; RNA Interference; Tretinoin | 2005 |
Aging of mipafox-inhibited human acetylcholinesterase proceeds by displacement of both isopropylamine groups to yield a phosphate adduct.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Humans; Isoflurophate; Kinetics; Mass Spectrometry; Phosphates; Propylamines; Sensitivity and Specificity; Time Factors | 2006 |
Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH).
Topics: Acetylcholinesterase; Biodegradation, Environmental; Carboxylic Ester Hydrolases; Cell Line, Tumor; Humans; Insecticides; Isoflurophate; Nervous System; Neurites; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Phosphoric Monoester Hydrolases; Toxicity Tests | 2006 |
Comparison of chromaffin cells from several animal sources for their use as an in vitro model to study the mechanism of organophosphorous toxicity.
Topics: Animals; Carboxylic Ester Hydrolases; Cattle; Cells, Cultured; Chromaffin Cells; Goats; Horses; Isoflurophate; Organophosphorus Compounds; Paraoxon; Sheep; Species Specificity; Swine | 2006 |
Recovery of neuropathy target esterase activity after inhibition with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures.
Topics: Animals; Carboxylic Ester Hydrolases; Cattle; Cells, Cultured; Chromaffin Cells; Enzyme Inhibitors; Isoflurophate; Neurotoxicity Syndromes; Organophosphorus Compounds; Recovery of Function; Time Factors | 2007 |
Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer.
Topics: Adenoviridae; Animals; Carboxylic Ester Hydrolases; Cattle; Cells, Cultured; Chromaffin Cells; Genetic Vectors; Humans; Isoflurophate; Paraoxon; Transfection; Valerates | 2007 |
The search of the target of promotion: Phenylbenzoate esterase activities in hen peripheral nerve.
Topics: Animals; Benzoates; Carboxylic Ester Hydrolases; Chickens; Enzyme Inhibitors; Isoflurophate; Phenylmethylsulfonyl Fluoride; Sciatic Nerve; Substrate Specificity | 2007 |
Mechanism of aging of mipafox-inhibited butyrylcholinesterase.
Topics: Aging; Animals; Binding Sites; Butyrylcholinesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Crystallography, X-Ray; Horses; Isoflurophate; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Biosensor assay of neuropathy target esterase in whole blood as a new approach to OPIDN risk assessment: review of progress.
Topics: Animals; Biomarkers; Biosensing Techniques; Carboxylic Ester Hydrolases; Chickens; Dose-Response Relationship, Drug; Electrochemistry; Enzymes, Immobilized; Female; Isoflurophate; Lymphocytes; Methylphenazonium Methosulfate; Monophenol Monooxygenase; Neurotoxicity Syndromes; Organophosphates; Risk Assessment | 2007 |
Molecular cloning and expression of the C-terminal domain of mouse NTE-related esterase.
Topics: Animals; Blotting, Western; Carboxylic Ester Hydrolases; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Gene Expression Regulation, Enzymologic; Isoflurophate; Membrane Proteins; Mice; Paraoxon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Valerates | 2007 |
Molecular cloning and expression of chicken neuropathy target esterase activity domain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Carboxylic Ester Hydrolases; Chickens; Chlorocebus aethiops; Cloning, Molecular; COS Cells; DNA, Complementary; Female; Humans; Isoflurophate; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Analysis; Sequence Homology, Amino Acid; Transfection | 2007 |
Constructs of human neuropathy target esterase catalytic domain containing mutations related to motor neuron disease have altered enzymatic properties.
Topics: Carboxylic Ester Hydrolases; Catalytic Domain; Chlorpyrifos; Enzyme Inhibitors; Humans; Hydrolysis; Isoflurophate; Kinetics; Motor Neuron Disease; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Spastic Paraplegia, Hereditary; Substrate Specificity; Valerates | 2010 |
Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Interactions; Enzyme Induction; Isoflurophate; Kinetics; Neurotoxicity Syndromes; Organophosphorus Compounds; Paraoxon | 2011 |
Interactions of neuropathy inducers and potentiators/promoters with soluble esterases.
Topics: Animals; Brain; Catalytic Domain; Chickens; Enzyme Inhibitors; Esterases; Isoflurophate; Kinetics; Nervous System Diseases; Organophosphorus Compounds; Paraoxon; Phenylmethylsulfonyl Fluoride; Sciatic Nerve; Solubility | 2013 |
Kinetic interactions of a neuropathy potentiator (phenylmethylsulfonyl fluoride) with the neuropathy target esterase and other membrane bound esterases.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Cell Membrane; Chickens; Enzyme Inhibitors; Esterases; Isoflurophate; Kinetics; Phenylmethylsulfonyl Fluoride | 2014 |
Separating esterase targets of organophosphorus compounds in the brain by preparative chromatography.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chemical Fractionation; Chickens; Cholinesterase Inhibitors; Chromatography; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Isoenzymes; Isoflurophate | 2014 |
Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox.
Topics: Chromatin Assembly and Disassembly; Embryonal Carcinoma Stem Cells; Genome, Human; Histones; Humans; Insecticides; Isoflurophate; Neurogenesis; Neurons; Nucleosomes; Paraoxon; Phenotype; Tretinoin | 2014 |
Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate- and acetylcholine-hydrolyzing activities in chicken brain.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Brain; Carboxylic Ester Hydrolases; Chickens; Hydrolysis; Isoflurophate; Organophosphorus Compounds; Phenylmethylsulfonyl Fluoride; Valerates | 2014 |
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches.
Topics: Acetylcholinesterase; Amino Acid Sequence; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Isoflurophate; Kinetics; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Oximes; Paraoxon; Phosphorylation; Protein Conformation; Sarin; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain.
Topics: Animals; Brain; Butyrylcholinesterase; Carboxylic Ester Hydrolases; Chickens; Chromatography, Liquid; Computational Biology; Dose-Response Relationship, Drug; Isoflurophate; Phenothiazines; Proteomics; Tandem Mass Spectrometry | 2017 |
Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells.
Topics: Animals; Biomarkers; Carboxylic Ester Hydrolases; Cell Differentiation; Cell Survival; Chlorpyrifos; Gene Expression Regulation, Developmental; Gene Silencing; Isoflurophate; Mice; Mouse Embryonic Stem Cells; Paraoxon | 2016 |
High concentration of trichlorfon (1mM) disrupts axonal cytoskeleton and decreases the expression of plasticity-related proteins in SH-SY5Y cells.
Topics: Acetylcholinesterase; Axons; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cholinesterase Inhibitors; Cytoskeleton; GAP-43 Protein; Humans; Insecticides; Isoflurophate; L-Lactate Dehydrogenase; Neuronal Plasticity; Paraoxon; Synapsins; Trichlorfon | 2017 |
L- and T-type calcium channel blockers protect against the inhibitory effects of mipafox on neurite outgrowth and plasticity-related proteins in SH-SY5Y cells.
Topics: Amiloride; Axons; Calcium Channel Blockers; Cell Line, Tumor; Humans; Insecticides; Isoflurophate; Neurites; Nimodipine | 2017 |
The Antidiabetic Drug Liraglutide Minimizes the Non-Cholinergic Neurotoxicity of the Pesticide Mipafox in SH-SY5Y Cells.
Topics: Cell Line, Tumor; Glucose; Humans; Hypoglycemic Agents; Interleukin-1beta; Isoflurophate; Liraglutide; Neuronal Outgrowth; Neuronal Plasticity; Neuroprotection; Neuroprotective Agents; Neurotoxicity Syndromes; Pesticides | 2019 |
Hydrolyzing activities of phenyl valerate sensitive to organophosphorus compounds paraoxon and mipafox in human neuroblastoma SH-SY5Y cells.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrolysis; Isoflurophate; Neuroblastoma; Organophosphorus Compounds; Paraoxon; Valerates | 2018 |