isoflurane and n-methylaspartate

isoflurane has been researched along with n-methylaspartate in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's13 (43.33)18.2507
2000's13 (43.33)29.6817
2010's3 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kendig, JJ; Savola, MK; Woodley, SJ1
Yang, J; Zorumski, CF1
Kendig, JJ; Maze, M; Savola, MK; Woodley, SJ1
el-Beheiry, H; Puil, E1
Baimbridge, KG; el-Beheiry, H; Puil, E1
Foster, AC; Gill, R; Woodruff, GN1
Arai, K; Fujita, T; Ishizaki, K; Yamazaki, M; Yoon, DM; Yoshida, N1
Bickler, PE; Buck, LT; Hansen, BM1
Yamazaki, M1
De Vente, J; Johns, RA; Zuo, Z1
Johns, RA; Pajewski, TN; Rengasamy, A1
Johns, RA; Tichotsky, A; Zuo, Z1
Cole, DJ; Drummond, JC; Harada, H; Kelly, PJ; Patel, PM1
Desmonts, JM; Dupont, H; Henzel-Rouellé, D; Keita, H; Mantz, J1
Baird, K; Bokesch, PM; Drummond-Webb, J; Kapural, L; Kapural, M; Mee, RB; Starr, NJ; Trapp, B1
Johns, RA; Tao, YX1
Breese, GR; Criswell, HE; Knapp, DJ; Ming, Z; Mueller, RA1
Dohi, S; Iida, H; Nagase, K; Ohata, H1
Cechova, S; Pajewski, TN1
Aono, M; Pearlstein, RD; Warner, DS; Wise-Faberowski, L1
Zheng, S; Zuo, Z1
Alkire, MT; McReynolds, JR; Nathan, SV1
Awan, S; Frässdorf, J; Preckel, B; Schlack, W; Toma, O; Weber, NC1
Dai, TJ; Hang, LH; Zeng, YM1
Pearlstein, RD; Warner, DS; Wise-Faberowski, L1
Baxter, MG; Crosby, G; Culley, DJ; Murphy, KL1
Chan, HH; Ng, YF; To, CH; Yap, MK1
Campbell, LL; Edmands, SD; Hall, AC; Hokenson, KE; Kim, SA; McKeon, JE; Sherrill, H; Stackpole, EE; Suarez, C; Tyson, JA1
Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ1
Grace, AA; Zimmerman, EC1

Trials

1 trial(s) available for isoflurane and n-methylaspartate

ArticleYear
Ketamine, not propofol, attenuates cerebrovascular response to carbon dioxide in humans with isoflurane anesthesia.
    Journal of clinical anesthesia, 2001, Volume: 13, Issue:8

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Heart Rate; Humans; Isoflurane; Ketamine; Male; Middle Cerebral Artery; N-Methylaspartate; Propofol

2001

Other Studies

29 other study(ies) available for isoflurane and n-methylaspartate

ArticleYear
Isoflurane depresses both glutamate- and peptide-mediated slow synaptic transmission in neonatal rat spinal cord.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Animals; Animals, Newborn; Glutamates; Glutamic Acid; In Vitro Techniques; Isoflurane; N-Methylaspartate; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synapses; Synaptic Transmission

1991
Effects of isoflurane on N-methyl-D-aspartate gated ion channels in cultured rat hippocampal neurons.
    Annals of the New York Academy of Sciences, 1991, Volume: 625

    Topics: Animals; Animals, Newborn; Cells, Cultured; Hippocampus; Ion Channel Gating; Ion Channels; Isoflurane; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate

1991
Isoflurane and an alpha 2-adrenoceptor agonist suppress nociceptive neurotransmission in neonatal rat spinal cord.
    Anesthesiology, 1991, Volume: 75, Issue:3

    Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, General; Animals; Animals, Newborn; Drug Interactions; Electric Stimulation; Imidazoles; In Vitro Techniques; Isoflurane; Medetomidine; N-Methylaspartate; Nociceptors; Rats; Rats, Inbred Strains; Reflex, Monosynaptic; Spinal Cord; Substance P; Synaptic Transmission

1991
Anaesthetic suppression of transmitter actions in neocortex.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Acetylcholine; Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Guinea Pigs; In Vitro Techniques; Isoflurane; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents

1990
Anesthetic effects on glutamate-stimulated increase in intraneuronal calcium.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Amino Acids; Anesthetics; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Fura-2; Glutamates; Halothane; Hippocampus; Intracellular Fluid; Isoflurane; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Spectrometry, Fluorescence; Verapamil

1990
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors

1988
Intrathecal administration of N-methyl-D-aspartate receptor antagonist reduces the minimum alveolar anaesthetic concentration of isoflurane in rats.
    British journal of anaesthesia, 1995, Volume: 75, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Inhalation; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Isoflurane; Male; N-Methylaspartate; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1995
Effects of isoflurane and hypothermia on glutamate receptor-mediated calcium influx in brain slices.
    Anesthesiology, 1994, Volume: 81, Issue:6

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Calcium; Cytosol; Excitatory Amino Acid Antagonists; Hypothermia; In Vitro Techniques; Isoflurane; L-Lactate Dehydrogenase; N-Methylaspartate; Rats; Receptors, Glutamate

1994
[The influence of intrathecal NMDA receptor antagonist on the isoflurane MAC and on the motor function].
    Masui. The Japanese journal of anesthesiology, 1996, Volume: 45, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord

1996
Halothane and isoflurane dose-dependently inhibit the cyclic GMP increase caused by N-methyl-D-aspartate in rat cerebellum: novel localization and quantitation by in vitro autoradiography.
    Neuroscience, 1996, Volume: 74, Issue:4

    Topics: Anesthetics, General; Animals; Autoradiography; Cerebellum; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Halothane; Immunohistochemistry; In Vitro Techniques; Isoflurane; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

1996
Inhalational anesthetic effects on rat cerebellar nitric oxide and cyclic guanosine monophosphate production.
    Anesthesiology, 1997, Volume: 86, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Arginine; Cerebellum; Citrulline; Cyclic GMP; Drug Interactions; Excitatory Amino Acid Agonists; Halothane; Isoflurane; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tritium

1997
Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.
    Neuroscience, 1999, Volume: 93, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Halothane; Isoflurane; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Signal Transduction

1999
Isoflurane reduces N-methyl-D-aspartate toxicity in vivo in the rat cerebral cortex.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Binding, Competitive; Cerebral Cortex; Cerebral Infarction; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoflurane; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate

1999
Halothane and isoflurane increase spontaneous but reduce the N-methyl-D-aspartate-evoked dopamine release in rat striatal slices: evidence for direct presynaptic effects.
    Anesthesiology, 1999, Volume: 91, Issue:6

    Topics: Algorithms; Anesthetics, Inhalation; Animals; Dopamine; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; Halothane; In Vitro Techniques; Isoflurane; Male; N-Methylaspartate; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Presynaptic; Synaptosomes; Tetrodotoxin

1999
Neuroprotective, anesthetic, and cardiovascular effects of the NMDA antagonist, CNS 5161A, in isoflurane-anesthetized lambs.
    Anesthesiology, 2000, Volume: 93, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Brain; Cardiopulmonary Bypass; Heart Arrest, Induced; Hemodynamics; In Situ Hybridization; Isoflurane; N-Methylaspartate; Neuroprotective Agents; Sheep

2000
Effect of the deficiency of spinal PSD-95/SAP90 on the minimum alveolar anesthetic concentration of isoflurane in rats.
    Anesthesiology, 2001, Volume: 94, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agonists; Injections, Spinal; Intracellular Signaling Peptides and Proteins; Isoflurane; Male; Membrane Proteins; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Oligoribonucleotides, Antisense; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord

2001
Differential modulation of GABA- and NMDA-gated currents by ethanol and isoflurane in cultured rat cerebral cortical neurons.
    Brain research, 2001, Nov-30, Volume: 920, Issue:1-2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Cells, Cultured; Central Nervous System Depressants; Cerebral Cortex; Dose-Response Relationship, Drug; Electrophysiology; Ethanol; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Ion Channel Gating; Isoflurane; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Reflex

2001
The soluble guanylyl cyclase inhibitor ODQ, 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one, dose-dependently reduces the threshold for isoflurane anesthesia in rats.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Isoflurane; Male; N-Methylaspartate; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Signal Transduction

2004
Apoptosis is not enhanced in primary mixed neuronal/glial cultures protected by isoflurane against N-methyl-D-aspartate excitotoxicity.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Apoptosis; Caspase 3; Caspases; Cell Nucleus; Coculture Techniques; Culture Media; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; In Situ Nick-End Labeling; Isoflurane; N-Methylaspartate; Necrosis; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

2004
Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices.
    Brain research, 2005, Aug-30, Volume: 1054, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Cell Survival; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Isoflurane; Male; N-Methylaspartate; Pertussis Toxin; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate

2005
Memory enhancing effect of low-dose sevoflurane does not occur in basolateral amygdala-lesioned rats.
    Anesthesiology, 2005, Volume: 103, Issue:6

    Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Agonists; Halothane; Hyperalgesia; Isoflurane; Male; Memory; Methyl Ethers; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sevoflurane

2005
Effects of nitrous oxide on the rat heart in vivo: another inhalational anesthetic that preconditions the heart?
    Anesthesiology, 2005, Volume: 103, Issue:6

    Topics: Amygdala; Anesthetics, Inhalation; Animals; Avoidance Learning; Desflurane; Excitatory Amino Acid Agonists; Halothane; Hyperalgesia; Isoflurane; Male; Memory; Methyl Ethers; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sevoflurane

2005
Spinal N-methyl-D-aspartate receptors may mediate the analgesic effects of emulsified halogenated anesthetics.
    Pharmacology, 2006, Volume: 76, Issue:3

    Topics: Analgesics; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane; Excitatory Amino Acid Agonists; Female; Injections, Spinal; Isoflurane; Methyl Ethers; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Pain Measurement; Pain Threshold; Receptors, N-Methyl-D-Aspartate; Sevoflurane; Spinal Cord

2006
NMDA-induced apoptosis in mixed neuronal/glial cortical cell cultures: the effects of isoflurane and dizocilpine.
    Journal of neurosurgical anesthesiology, 2006, Volume: 18, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Apoptosis; Caspase 3; Caspase 9; Caspases; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Dizocilpine Maleate; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Situ Nick-End Labeling; Isoflurane; L-Lactate Dehydrogenase; N-Methylaspartate; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley

2006
Different behavioral effects of neurotoxic dorsal hippocampal lesions placed under either isoflurane or propofol anesthesia.
    Hippocampus, 2008, Volume: 18, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Behavior, Animal; Denervation; Hippocampus; Isoflurane; Learning; Learning Disabilities; Male; Memory; Memory Disorders; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Propofol; Rats; Rats, Inbred F344

2008
The characteristics of multifocal electroretinogram in isolated perfused porcine eye: cellular contributions to the in vitro porcine mfERG.
    Documenta ophthalmologica. Advances in ophthalmology, 2008, Volume: 117, Issue:3

    Topics: Aminobutyrates; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Electroretinography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoflurane; N-Methylaspartate; Pipecolic Acids; Propofol; Retina; Sodium Channel Blockers; Swine; Tetrodotoxin

2008
Assessment of general anaesthetic cytotoxicity in murine cortical neurones in dissociated culture.
    Toxicology, 2011, Apr-28, Volume: 283, Issue:1

    Topics: Anesthetics, General; Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; gamma-Aminobutyric Acid; Isoflurane; Ketamine; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Nitrous Oxide

2011
Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke.
    Anesthesiology, 2011, Volume: 115, Issue:5

    Topics: Animals; Binding Sites; Brain; Disease Models, Animal; Isoflurane; Male; N-Methylaspartate; Neuroprotective Agents; Nitrous Oxide; Rats; Rats, Sprague-Dawley; Stroke; Thromboembolism; Tissue Plasminogen Activator; Xenon

2011
The Nucleus Reuniens of the Midline Thalamus Gates Prefrontal-Hippocampal Modulation of Ventral Tegmental Area Dopamine Neuron Activity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 08-24, Volume: 36, Issue:34

    Topics: Action Potentials; Amphetamine; Anesthetics, Inhalation; Anesthetics, Local; Animals; Central Nervous System Stimulants; Dopaminergic Neurons; Excitatory Amino Acid Agonists; Hippocampus; Hyperkinesis; Isoflurane; Male; Midline Thalamic Nuclei; N-Methylaspartate; Neural Pathways; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Ventral Tegmental Area

2016
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