isoflurane and adenosine

isoflurane has been researched along with adenosine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.13)18.7374
1990's20 (51.28)18.2507
2000's11 (28.21)29.6817
2010's5 (12.82)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sollevi, A1
Hennes, HJ; Jantzen, JP; Rochels, R; Wallenfang, T1
Baier, H; Christ, M; Conzen, PF; Habazettl, H; Peter, K; Vollmar, B1
Larach, DR; Schuler, HG1
Hartman, JC; Kampine, JP; Schmeling, WT; Warltier, DC2
Abdel-Latif, M; Crystal, GJ; Czinn, EA; Kim, SJ; Mason, WR; Salem, MR1
Anaes, FC; Hatano, Y; Mori, K; Nakamura, K; Nishiwada, M; Yakushiji, T1
Larach, DR; Peterson, CJ; Schuler, HG; Skeehan, TM1
Buffington, CW; Duttlinger, NC; Huang, AH; Levine, A; Romson, JL1
Longnecker, DE; Seyde, WC1
Ekblom, A; Sandelin, K; Segerdahl, M; Sollevi, A; Wickman, M1
Crystal, GJ; Czinn, EA; Salem, MR; Silver, JM1
Hartman, JC; Kersten, JR; Pagel, PS; Warltier, DC1
Cason, BA; Hickey, RF; Shubayev, I1
Ekblom, A; Persson, E; Segerdahl, M; Sollevi, A1
Irestedt, L; Segerdahl, M; Sollevi, A1
Campisi, P; Carmichael, FJ; Crawford, M; Khanna, JM; Orrego, H1
Corso, CO; Fujita, Y; Habazettl, H; Messmer, K; Yada, T1
Becker, GL; Howard, BJ; Landers, DF; Pohorecki, R1
Hahn, RG1
Duffy, L; Griffin, JD; Sá Rêgo, MM; Shearer, VE; White, PF; Whitten, CW; Zárate, E1
Morgan-Hughes, NJ; Sherry, KM1
Carmichael, FJ; Crawford, MW; Cray, SH; Khayyam, N1
Bosnjak, ZJ; Fujimoto, K; Kwok, WM1
Eisemann, C; Roewer, N; Tas, PW1
Albrecht, RF; Hoffman, WE; Jonjev, ZS2
Imamura, H; Nakao, S; Otani, H; Shingu, K; Uchiyama, Y; Wakeno-Takahashi, M1
Bénard, F; Bentourkia, M; Croteau, E; Lecomte, R; Paquette, M; Rousseau, J1
Fukuda, K; Fukunaga, A; Hanaoka, K; Hayashida, M; Ichinohe, T; Kaneko, Y; Mamiya, H; Sakurai, S1
Asakawa, M; Badgley, BL; Erb, HN; Gleed, RD; Ludders, JW; Posner, LP1
Akça, O; Dalton, JE; Govinda, R; Kasuya, Y; Obal, D; Rauch, S; Sessler, DI; Turan, A1
Ge, J; Wu, J; You, J; Zou, Y1
Brown, KM; D'Agati, VD; Ham, A; Kim, JY; Kim, M; Lee, HT1
Brown, KM; Ham, A; Kim, KY; Kim, M; Lee, HT1
Baer, AG; Baghdoyan, HA; Brown, JB; Cliff, AM; Garcia, BJ; Jacobson, DA; Jones, PC; Lydic, R; Mi, W; Price, JM; Romero, J; Zhang, X1

Trials

6 trial(s) available for isoflurane and adenosine

ArticleYear
Peroperative adenosine infusion reduces the requirements for isoflurane and postoperative analgesics.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:6

    Topics: Adenosine; Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia; Conscious Sedation; Double-Blind Method; Female; Flicker Fusion; Humans; Infusions, Intravenous; Intraoperative Period; Isoflurane; Mammaplasty; Mastectomy; Middle Aged; Pain Measurement; Pain, Postoperative

1995
Peroperative adenosine infusion reduces isoflurane concentrations during general anesthesia for shoulder surgery.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:7

    Topics: Adenosine; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Anesthetics, Inhalation; Double-Blind Method; Female; Humans; Isoflurane; Male; Middle Aged; Shoulder Joint

1996
Antinociceptive effect of perioperative adenosine infusion in abdominal hysterectomy.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:4

    Topics: Adenosine; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Hysterectomy; Isoflurane; Middle Aged; Pain, Postoperative

1997
Comparison of adenosine and remifentanil infusions as adjuvants to desflurane anesthesia.
    Anesthesiology, 1999, Volume: 90, Issue:4

    Topics: Adenosine; Adult; Analgesics, Opioid; Anesthetics, Inhalation; Blood Pressure; Desflurane; Female; Heart Rate; Humans; Isoflurane; Middle Aged; Piperidines; Remifentanil

1999
Effects of adenosine infusion on the minimum alveolar concentration of isoflurane in dogs.
    Veterinary anaesthesia and analgesia, 2007, Volume: 34, Issue:1

    Topics: Adenosine; Anesthetics, Inhalation; Animals; Blood Pressure; Dogs; Drug Interactions; Female; Heart Rate; Infusions, Intravenous; Isoflurane; Male; Pulmonary Alveoli

2007
The effect of aminophylline on loss of consciousness, bispectral index, propofol requirement, and minimum alveolar concentration of desflurane in volunteers.
    Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2

    Topics: Adenosine; Adolescent; Adult; Aminophylline; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Consciousness; Consciousness Monitors; Cross-Over Studies; Desflurane; Double-Blind Method; Humans; Isoflurane; Male; Propofol; Pulmonary Alveoli; Young Adult

2010

Other Studies

33 other study(ies) available for isoflurane and adenosine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Adenosine infusion during isoflurane-nitrous oxide anaesthesia: indications of perioperative analgesic effect.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:6

    Topics: Adenosine; Adult; Analgesics; Anesthesia, Inhalation; Female; Humans; Infusions, Intravenous; Isoflurane; Middle Aged; Nitrous Oxide; Pilot Projects; Surgical Procedures, Operative

1992
Deliberate arterial hypotension does not reduce intraocular pressure in pigs.
    Anesthesiology, 1992, Volume: 77, Issue:3

    Topics: Adenosine; Animals; Hemodynamics; Hypotension, Controlled; Intracranial Pressure; Intraocular Pressure; Isoflurane; Nitroprusside; Pulmonary Gas Exchange; Swine

1992
Coronary microcirculation during halothane, enflurane, isoflurane, and adenosine in dogs.
    Anesthesiology, 1992, Volume: 76, Issue:2

    Topics: Adenosine; Animals; Coronary Circulation; Dogs; Enflurane; Halothane; Hemodynamics; Hypotension; Isoflurane; Microcirculation

1992
Direct vasodilation by sevoflurane, isoflurane, and halothane alters coronary flow reserve in the isolated rat heart.
    Anesthesiology, 1991, Volume: 75, Issue:2

    Topics: Adenosine; Anesthetics; Animals; Coronary Circulation; Ethers; Halothane; Hemodynamics; Isoflurane; Male; Methyl Ethers; Rats; Rats, Inbred Strains; Sevoflurane; Vasodilation

1991
Alterations in collateral blood flow produced by isoflurane in a chronically instrumented canine model of multivessel coronary artery disease.
    Anesthesiology, 1991, Volume: 74, Issue:1

    Topics: Adenosine; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Female; Hemodynamics; Isoflurane; Male

1991
Steal-prone coronary circulation in chronically instrumented dogs: isoflurane versus adenosine.
    Anesthesiology, 1991, Volume: 74, Issue:4

    Topics: Adenosine; Animals; Coronary Circulation; Dogs; Hemodynamics; Isoflurane; Myocardial Contraction; Myocardial Reperfusion

1991
Intracoronary isoflurane causes marked vasodilation in canine hearts.
    Anesthesiology, 1991, Volume: 74, Issue:4

    Topics: Adenosine; Anesthesia, Inhalation; Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Fentanyl; Hemodynamics; Isoflurane; Male; Oxygen Consumption; Vasodilation

1991
Comparison of the direct effects of halothane and isoflurane on large and small coronary arteries isolated from dogs.
    Anesthesiology, 1990, Volume: 73, Issue:3

    Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Halothane; In Vitro Techniques; Isoflurane; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin

1990
Direct effects of myocardial depressant drugs on coronary vascular tone: anesthetic vasodilation by halothane and isoflurane.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1

    Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Coronary Vessels; Dose-Response Relationship, Drug; Halothane; Heart; Isoflurane; Male; Muscle, Smooth, Vascular; Oxygen Consumption; Rats; Tetrodotoxin; Vascular Resistance; Vasodilation

1990
Isoflurane induces coronary steal in a canine model of chronic coronary occlusion.
    Anesthesiology, 1987, Volume: 66, Issue:3

    Topics: Adenosine; Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; Female; Halothane; Isoflurane; Male; Nitrous Oxide; Perfusion; Vascular Resistance; Vasodilator Agents

1987
Cerebral oxygen tension in rats during deliberate hypotension with sodium nitroprusside, 2-chloroadenosine, or deep isoflurane anesthesia.
    Anesthesiology, 1986, Volume: 64, Issue:4

    Topics: 2-Chloroadenosine; Adenosine; Anesthesia; Animals; Blood Pressure; Brain; Cyanides; Ferricyanides; Heart Rate; Hypotension, Controlled; Isoflurane; Male; Methyl Ethers; Nitroprusside; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains

1986
Coronary vasodilation by isoflurane. Abrupt versus gradual administration.
    Anesthesiology, 1995, Volume: 82, Issue:2

    Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Drug Administration Schedule; Female; Hemodynamics; Isoflurane; Male; Myocardium; Oxygen Consumption; Vasodilation

1995
Volatile anesthetics and coronary collateral circulation.
    Advances in pharmacology (San Diego, Calif.), 1994, Volume: 31

    Topics: Adenosine; Anesthetics; Animals; Collateral Circulation; Coronary Circulation; Dogs; Ethers; Female; Isoflurane; Male; Methyl Ethers; Sevoflurane; Vasodilation

1994
Blockade of adenosine triphosphate-sensitive potassium channels eliminates isoflurane-induced coronary artery vasodilation.
    Anesthesiology, 1994, Volume: 81, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Glyburide; Heart Rate; Isoflurane; Nitroprusside; Potassium Channels; Swine; Vasodilation

1994
Role of adenosine in the ethanol-induced potentiation of the effects of general anesthetics in rats.
    European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3

    Topics: Acetic Acid; Adenosine; Anesthetics, Inhalation; Animals; Drug Synergism; Ethanol; Ethers; Isoflurane; Male; Methyl Ethers; Pulmonary Alveoli; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sevoflurane; Theophylline

1997
Comparative effects of hypotension due to isoflurane, nitroglycerin, and adenosine on subendocardial microcirculation: observation of the in situ beating swine heart under critical stenosis.
    Anesthesiology, 1997, Volume: 87, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Coronary Disease; Endocardium; Female; Hemodynamics; Hydrogen-Ion Concentration; Isoflurane; Male; Microcirculation; Nitroglycerin; Swine

1997
Energy status in anoxic rat hepatocytes: effects of isoflurane, solution composition, and hypothermia.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1995, Volume: 1, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Allopurinol; Anesthetics, Inhalation; Animals; Cell Hypoxia; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Glutathione; Hypothermia, Induced; Hypoxia; Insulin; Isoflurane; Isotonic Solutions; Liver; Male; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley

1995
Adenosine and isoflurane concentrations.
    Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:9

    Topics: Adenosine; Anesthesia, Inhalation; Anesthetics, Inhalation; Anti-Arrhythmia Agents; Area Under Curve; Humans; Isoflurane; Shoulder Joint

1997
Effect of anaesthesia on the cardiac response to intravenous adenosine.
    British journal of anaesthesia, 2000, Volume: 84, Issue:5

    Topics: Adenosine; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Arrhythmia Agents; Coronary Artery Bypass; Drug Interactions; Female; Fentanyl; Heart; Heart Rate; Humans; Injections, Intravenous; Isoflurane; Male; Time Factors

2000
Effects of hypoxia and isoflurane on liver blood flow: the role of adenosine.
    British journal of anaesthesia, 2001, Volume: 86, Issue:3

    Topics: Adenosine; Anesthetics, Inhalation; Animals; Hemodynamics; Hypoxia; Isoflurane; Liver Circulation; Male; Rats; Rats, Sprague-Dawley; Vascular Resistance

2001
Isoflurane-induced facilitation of the cardiac sarcolemmal K(ATP) channel.
    Anesthesiology, 2002, Volume: 97, Issue:1

    Topics: 2,4-Dinitrophenol; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Benzopyrans; Dihydropyridines; Guinea Pigs; Heart; Isoflurane; Potassium Channels; Protein Kinase C

2002
The volatile anesthetic isoflurane suppresses spontaneous calcium oscillations in vitro in rat hippocampal neurons by activation of adenosine A1 receptors.
    Neuroscience letters, 2003, Mar-06, Volume: 338, Issue:3

    Topics: Adenosine; Analgesics; Anesthetics, Inhalation; Animals; Calcium Signaling; Cells, Cultured; Fetus; Hippocampus; Isoflurane; Microscopy, Confocal; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1

2003
Glyburide decreases myocardial oxygen pressure in dogs.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:2

    Topics: Adenosine; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Coronary Circulation; Depression, Chemical; Desflurane; Dogs; Glyburide; Heart; Heart Rate; Hydrogen-Ion Concentration; Isoflurane; Male; Myocardium; Nitroprusside; Oxygen Consumption; Potassium Channel Blockers; Vasodilator Agents

2003
Comparison of adenosine, isoflurane, and desflurane on myocardial tissue oxygen pressure during coronary artery constriction in dogs.
    Journal of cardiothoracic and vascular anesthesia, 2003, Volume: 17, Issue:4

    Topics: Adenosine; Animals; Blood Pressure; Carbon Dioxide; Constriction, Pathologic; Coronary Circulation; Coronary Stenosis; Desflurane; Disease Models, Animal; Dogs; Heart Rate; Hypotension; Isoflurane; Male; Models, Cardiovascular; Myocardium; Oxygen; Oxygen Consumption; Prospective Studies; Random Allocation; Vasodilator Agents

2003
Adenosine and a nitric oxide donor enhances cardioprotection by preconditioning with isoflurane through mitochondrial adenosine triphosphate-sensitive K+ channel-dependent and -independent mechanisms.
    Anesthesiology, 2004, Volume: 100, Issue:3

    Topics: Adenosine; Anesthetics, Inhalation; Animals; Cardiovascular Agents; Diazoxide; Dose-Response Relationship, Drug; Flavoproteins; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Membrane Proteins; Mitochondria, Heart; Myocardial Infarction; Nitric Oxide Donors; Oxidation-Reduction; Potassium Channels; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine

2004
Quantitative myocardial perfusion and coronary reserve in rats with 13N-ammonia and small animal PET: impact of anesthesia and pharmacologic stress agents.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:11

    Topics: Adenosine; Ammonia; Anesthetics; Animals; Artifacts; Coronary Circulation; Dobutamine; Exercise Test; Feasibility Studies; Heart; Isoflurane; Male; Nitrogen Radioisotopes; Positron-Emission Tomography; Propofol; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley

2004
The characteristics of intravenous adenosine-induced antinociception in a rabbit model of acute nociceptive pain: a comparative study with remifentanil.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Heart Rate; Infusions, Intravenous; Isoflurane; Male; Nociceptors; Pain; Pain Measurement; Piperidines; Rabbits; Remifentanil; Respiration

2006
Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload.
    American journal of physiology. Heart and circulatory physiology, 2012, Nov-15, Volume: 303, Issue:10

    Topics: Adenosine; Animals; Coronary Circulation; Disease Models, Animal; Echocardiography, Doppler; Feasibility Studies; Hyperemia; Isoflurane; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Predictive Value of Tests; Reproducibility of Results; Stroke Volume; Vasodilator Agents; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure

2012
The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.
    Kidney international, 2013, Volume: 84, Issue:1

    Topics: 5'-Nucleotidase; Acute Kidney Injury; Adenosine; Anesthetics, Inhalation; Animals; Antibodies, Neutralizing; Apoptosis; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Isoflurane; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neutrophil Infiltration; Purinergic P1 Receptor Antagonists; Reperfusion Injury; RNA, Messenger; Time Factors; Transforming Growth Factor beta1; Volatilization

2013
The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Amides; Anesthetics, Inhalation; Animals; Antigens, CD; Cadherins; Cell Line, Transformed; Cell-Derived Microparticles; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoflurane; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Phosphatase; Pyridines; rho-Associated Kinases; Signal Transduction

2014
Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia.
    Journal of neurophysiology, 2020, 06-01, Volume: 123, Issue:6

    Topics: Acetylcholine; Adenosine; Anesthesia; Anesthetics, Inhalation; Animals; Isoflurane; Machine Learning; Male; Mice; Mice, Inbred C57BL; Microdialysis; Nerve Net; Norepinephrine; Prefrontal Cortex; Unconsciousness; Wakefulness

2020