isofloxythepin has been researched along with spiperone in 2 studies
| Studies (isofloxythepin) | Trials (isofloxythepin) | Recent Studies (post-2010) (isofloxythepin) | Studies (spiperone) | Trials (spiperone) | Recent Studies (post-2010) (spiperone) |
|---|---|---|---|---|---|
| 26 | 4 | 0 | 2,944 | 13 | 85 |
| Protein | Taxonomy | isofloxythepin (IC50) | spiperone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0008 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.0005 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.097 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0635 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0001 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lau, YS; Runice, C | 1 |
| Anderson, TM; Fung, YK; Lau, YS | 1 |
2 other study(ies) available for isofloxythepin and spiperone
| Article | Year |
|---|---|
Prolonged inhibition of striatal dopamine receptor sites by isofloxythepin.
Topics: Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; Dibenzothiepins; Dose-Response Relationship, Drug; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior | 1985 |
Antagonistic effects of isofloxythepin on dopamine D1 and D2 receptors and behaviors in rats.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Dibenzothiepins; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Grooming; Male; Neostriatum; Nucleus Accumbens; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Stereotyped Behavior | 1997 |