isodibut has been researched along with naphthalimides in 15 studies
| Studies (isodibut) | Trials (isodibut) | Recent Studies (post-2010) (isodibut) | Studies (naphthalimides) | Trials (naphthalimides) | Recent Studies (post-2010) (naphthalimides) |
|---|---|---|---|---|---|
| 27 | 1 | 13 | 1,045 | 48 | 738 |
| Protein | Taxonomy | isodibut (IC50) | naphthalimides (IC50) |
|---|---|---|---|
| Chain A, Cholix toxin | Vibrio cholerae | 0.411 | |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | 1.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 9 (60.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, DT; Mekalanos, JJ; Pierson, E; Shakhnovich, EA | 1 |
| Waldor, MK | 1 |
| Hung, DT; Lee, K; Mekalanos, JJ; Pierson, E; Shakhnovich, EA | 1 |
| Mekalanos, JJ; Shakhnovich, EA; Sturtevant, D | 1 |
| Hsiao, A; Kan, B; Kulkarni, RV; Xu, X; Zhu, J | 1 |
| Chakrabarti, P; Chatterjee, T; Dey, S; Hoque, KM; Mukherjee, D; Pal, A | 1 |
| Cao, X; Childers, BM; Demeler, B; Hart, PJ; Klose, KE; Weber, GG | 1 |
| Chakrabarti, P; Chatterjee, BK; Chatterjee, T; Dey, S; Pal, A | 1 |
| Alexandre, S; Dé, E; Jouenne, T; Marti, S; Mlouka, MB; Nait Chabane, Y; Nicol, M; Pestel-Caron, M; Vila, J | 1 |
| Anthouard, R; DiRita, VJ | 1 |
| Choi, CH; Oh, MH | 1 |
| Chatsudthipong, V; Muanprasat, C; Pongkorpsakol, P; Satitsri, S; Srimanote, P | 1 |
| Dé, E; Nicol, M; Reffuveille, F; Thébault, P | 1 |
| Benitez, JA; Silva, AJ; Wang, H | 1 |
| Acharya, S; Chakrabarti, P; Chatterjee, BK; Chatterjee, T; Gucchait, A; Hoque, KM; Jana, SK; Misra, AK; Paul, S; Saha, T | 1 |
1 review(s) available for isodibut and naphthalimides
| Article | Year |
|---|---|
Chemical biology applied to the study of bacterial pathogens.
Topics: Anti-Bacterial Agents; Bacterial Secretion Systems; Bacterial Toxins; Butyrates; Drug Design; Drug Evaluation, Preclinical; Fimbriae, Bacterial; Gene Expression; Gram-Negative Bacteria; Gram-Positive Bacteria; Naphthalimides; Small Molecule Libraries | 2015 |
14 other study(ies) available for isodibut and naphthalimides
| Article | Year |
|---|---|
Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Butyrates; Cell Line; Cholera; Cholera Toxin; Fimbriae, Bacterial; Gene Expression Regulation, Bacterial; Intestine, Small; Mice; Microbial Sensitivity Tests; Naphthalenes; Naphthalimides; Transcription Factors; Vibrio cholerae; Virulence; Virulence Factors | 2005 |
Disarming pathogens--a new approach for antibiotic development.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Butyrates; Cholera Toxin; Drug Design; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Intestine, Small; Mice; Naphthalenes; Naphthalimides; Transcription Factors; Vibrio cholerae; Virulence; Virulence Factors | 2006 |
Virstatin inhibits dimerization of the transcriptional activator ToxT.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Butyrates; Dimerization; Dose-Response Relationship, Drug; Naphthalenes; Naphthalimides; Promoter Regions, Genetic; Protein Binding; Trans-Activators; Transcription Factors; Vibrio cholerae | 2007 |
Molecular mechanisms of virstatin resistance by non-O1/non-O139 strains of Vibrio cholerae.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Blotting, Western; Butyrates; Drug Resistance, Bacterial; Genome, Bacterial; Intestine, Small; Mice; Molecular Sequence Data; Naphthalenes; Naphthalimides; Promoter Regions, Genetic; Sequence Homology, Amino Acid; Transcription Factors; Vibrio cholerae; Virulence | 2007 |
Direct regulation by the Vibrio cholerae regulator ToxT to modulate colonization and anticolonization pilus expression.
Topics: Animals; Bacterial Proteins; Butyrates; Culture Media; Dimerization; Fimbriae Proteins; Fimbriae, Bacterial; Gene Expression Regulation, Bacterial; Hemagglutinins; Humans; Mannose-Binding Lectin; Multigene Family; Naphthalimides; Transcription Factors; Vibrio cholerae; Virulence Factors | 2009 |
Accessory cholera enterotoxin, Ace, from Vibrio cholerae: structure, unfolding, and virstatin binding.
Topics: Algorithms; Amino Acid Sequence; Bacteria; Base Sequence; Butyrates; Cholera Toxin; Circular Dichroism; Dose-Response Relationship, Drug; Glutaral; Kinetics; Microbial Viability; Models, Molecular; Molecular Sequence Data; Naphthalimides; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Unfolding; Recombinant Proteins; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Spectrometry, Fluorescence; Vibrio cholerae | 2011 |
N-terminal residues of the Vibrio cholerae virulence regulatory protein ToxT involved in dimerization and modulation by fatty acids.
Topics: Amino Acid Substitution; Animals; Bacterial Proteins; Bile; Butyrates; Cholera; Fatty Acids, Monounsaturated; Humans; Intestinal Mucosa; Intestines; Mice; Mutation, Missense; Naphthalimides; Protein Multimerization; Protein Structure, Tertiary; Transcription Factors; Transcription, Genetic; Vibrio cholerae; Virulence | 2011 |
Interaction of virstatin with human serum albumin: spectroscopic analysis and molecular modeling.
Topics: Butyrates; Circular Dichroism; Fluorescence Resonance Energy Transfer; Humans; Models, Molecular; Molecular Structure; Naphthalimides; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2012 |
Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Biofilms; Butyrates; Fimbriae, Bacterial; Locomotion; Microscopy, Atomic Force; Naphthalimides | 2014 |
Role of LuxIR Homologue AnoIR in Acinetobacter nosocomialis and the Effect of Virstatin on the Expression of anoR Gene.
Topics: Acinetobacter; Bacterial Proteins; Biofilms; Butyrates; DNA, Bacterial; Gene Deletion; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Genome, Bacterial; Homoserine; Lactones; Locomotion; Molecular Sequence Data; Naphthalimides; Quorum Sensing; Sequence Analysis, DNA | 2015 |
Pathophysiological mechanisms of diarrhea caused by the Vibrio cholerae O1 El Tor variant: an in vivo study in mice.
Topics: Animals; Bacterial Typing Techniques; Butyrates; Chloride Channels; Cholera; Cholera Toxin; Cyclooxygenase 2; Diarrhea; Dinoprostone; Disease Models, Animal; Enteritis; Genetic Variation; Genotype; Intestines; Mice; Mice, Inbred CFTR; Mice, Inbred ICR; Naphthalimides; Nitric Oxide Synthase Type II; Vibrio cholerae O1 | 2016 |
Design of an anti-adhesive surface by a pilicide strategy.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Butyrates; Drug Design; Fimbriae, Bacterial; Hydrophobic and Hydrophilic Interactions; Locomotion; Naphthalimides; Propylamines; Silanes; Surface Properties; Virulence | 2016 |
3-Amino 1,8-naphthalimide, a structural analog of the anti-cholera drug virstatin inhibits chemically-biased swimming and swarming motility in vibrios.
Topics: 1-Naphthylamine; Animals; Bacterial Proteins; Butyrates; Cholera; Cholera Toxin; Flagella; Flagellin; Mice; Naphthalimides; Quinolones; Vibrio cholerae | 2017 |
Virstatin-Conjugated Gold Nanoparticle with Enhanced Antimicrobial Activity against the
Topics: Anti-Bacterial Agents; Biocompatible Materials; Butyrates; Gold; Kinetics; Materials Testing; Metal Nanoparticles; Microbial Sensitivity Tests; Molecular Structure; Naphthalimides; Particle Size; Vibrio cholerae O1 | 2021 |