Compounds > isodesmosine
Page last updated: 2024-08-21

isodesmosine and desmosine

isodesmosine has been researched along with desmosine in 140 studies

Research

Studies (140)

TimeframeStudies, this research(%)All Research%
pre-199052 (37.14)18.7374
1990's24 (17.14)18.2507
2000's23 (16.43)29.6817
2010's39 (27.86)24.3611
2020's2 (1.43)2.80

Authors

AuthorsStudies
Baurain, R; Lamy, F; Larochelle, JF1
Anwar, RA; Baig, KM; Gerber, GE1
Madaras, JA; Starcher, BC; Tepper, AS1
Bartos, F; Hodánová, M; Kosar, A; Ledvina, M; Wimmerová, J1
Burke, JM; Ross, R1
Bartos, F; Ledvina, M1
Goldstein, RA; Starcher, BC1
Boucek, RJ; Gunja-Smith, Z; Noble, NL; Simpson, CF1
Davis, NR1
Galione, MJ; Grodzki, WJ; Moses, RA; Starcher, BC1
Bhatnagar, RS; Urry, DW1
Starcher, BC1
Galione, MJ; Starcher, BC1
Baxter, BT; Dixit, SN; Drummond, IA; McGee, GS; Pearce, WH; Shively, VP; Yamauchi, M1
Muda, M; Mussini, E; Salomoni, M; Zuccato, E1
Bryan-Rhadfi, J; Ciccolella, DE; Crombie, G; Faris, B; Franzblau, C; Lucey, EC; Snider, GL; Stone, PJ1
Nakamura, F; Suyama, K1
Cantor, JO; Cerreta, JM; Evans, HE; Keller, S; Manahan, J; Turino, GM1
Cruickshank, FA; Lebwohl, M; Schwartz, E1
Codini, M; Fini, C; Floridi, A; Guida, E; Lucarelli, C; Palmerini, CA1
Davis, PF; Greenhill, NS; Kittelberger, R; Ryan, PA1
Ishimori, K; Kasuga, H; Matsuki, H; Verplanke, AJ; Watanabe, T1
Kuwana, T; Lunte, SM; Mohabbat, T; Wong, OS1
Anderson, MJ; Davis, PF; Osipowicz, J; Ryan, PA; Stehbens, WE; Sweeney, A1
Cantor, JO; Kaldany, RR; Mandl, I; Osman, M; Turino, GM1
Cantor, JO; Hosannah, Y; Keller, S; Mandl, I; Osman, M; Turino, GM1
Guay, M; Lagacé, G; Lamy, F1
Karatzas, CN; Khalili, AD; Nguyen, Q; Zarkadas, CG; Zarkadas, GC1
Soskel, NT1
Davril, M; Han, KK1
Benesová, J; Kosar, K; Ledvina, M; Wimmerová, J1
Bandô, Y; Haginaka, J; Kunitomo, M; Yamaguchi, Y; Yasuda, H1
Hirama, M; Kikuchi, Y; Tamiya, N; Tsuchikura, O1
Davril, M; Guay, M; Han, KK; Lamy, F1
Kato, M; Morimatsu, M; Nakamura, Y; Okamoto, K; Tanimura, A1
Cantor, JO; Keller, S; Mandl, I; Osman, M; Roffman, S; Turino, GM1
Bray, BA; Cantor, JO; Keller, S; Mandl, I; Turino, GM; Willhite, M1
Aikawa, J; Isemura, M; Munakata, H; Yosizawa, Z1
Boat, TF; Bruce, MC; Cheng, PW; Fanaroff, AA; Jentoft, N; Martin, RJ; Wedig, KE1
Gunja-Smith, Z; Woessner, JF1
Blount, JE; Harris, ED; Leach, RM1
Darnule, AT; Darnule, TV; Mandl, I; Turino, GM1
Cantor, JO; Cerreta, JM; Keller, S; Mandl, I; Osman, M; Turino, GM1
Hodánová, M; Ledvina, M; Velebný, V; Wimmerová, J1
King, GS; Starcher, BC1
Mecham, RP1
Keller, S; Mandl, I; Turino, GM1
Fujimoto, D; Yu, SY1
Hall, J; Hui, A; Muramoto, K; Ramachandran, J; Stern, R1
Kanta, J; Kasafírek, E; Velebný, V1
Davis, PF; Manning, JN; Ryan, PA; Skinner, SJ; Stehbens, WE1
Fujimoto, D1
Cerreta, J; Keller, S; Leppert, PC; Mandl, I1
Covault, HP; Dietz, AA; Lubrano, T; Rubinstein, HM1
Skinner, SJ1
Eyre, DR; Gross, J; Heathcote, JG1
Cerreta, J; Chrzanowski, P; Keller, S; Mandl, I; Osman, M; Turino, GM1
Bergeron-Lynn, G; Gochman, N; Jacobs, K; Lonky, SA; Smith, S1
Leach, RM; Rucker, RB; Van Dyke, GP1
Cerreta, J; Chrzanowski, P; Keller, S; Mandl, I; Turino, GM1
Bode, DC; Cumiskey, WR; Pagani, ED1
Berger, M; Dorkin, HL; Franzblau, C; Konstan, MW; Snider, GL; Stone, PJ1
Breuer, R; Bryan-Rhadfi, J; Ciccolella, DE; Franzblau, C; Gottlieb, DJ; O'Connor, GT; Shaw, HA; Snider, GL; Stone, PJ1
Franzblau, C; Korn, JH; Lally, EV; Miller, LC; North, H; Snider, GL; Stone, PJ; Strongwater, S; Tucker, LB1
Franzblau, C; Morris, TA; Snider, GL; Stone, PJ1
Franzblau, C; Lucey, EC; Snider, GL; Stone, PJ2
Sato, T; Tanno, T; Yoshinaga, K1
Osakabe, T; Seyama, Y; Yamashita, S1
Annoni, F; Bonavina, L; Butera, C; Colombo, L; Mussini, E; Peracchia, A; Venturi, M1
Atkinson, J; Duvivier, C; Giummelly, P; Lartaud-Idjouadiene, I; Niederhoffer, N; Peslin, R1
Nagura, H; Sawai, T; Suyama, K; Watanabe, M1
Antoniazzi, L; Bonavina, L; Bruno, A; Colombo, L; Mussini, E; Peracchia, A; Venturi, M1
Fachet, J; Fülöp, T; Jacob, MP; Katona, E; Robert, L; Wei, SM1
Beiser, A; Gottlieb, DJ; Stone, PJ1
Cetta, G; Grimm, R; Iadarola, P; Luisetti, M; Trisolini, R; Viglio, S; Zanaboni, G1
Balbi, B; Döring, G; Dowson, L; Grassi, V; Hill, SL; Iadarola, P; Luisetti, M; Lupi, A; Meloni, F; Meyer, KC; Stockley, RA; Tinelli, C; Trisolini, R; Viglio, S; Worlitzsch, D1
Bode, DC; Cumiskey, WR; Hamel, L; Pagani, ED; Silver, PJ; von Roemeling, R1
Akagawa, M; Suyama, K1
Stone, PJ1
Chillemi, C; Gigante, A; Miselli, M; Pasquali-Ronchetti, I; Quaglino, D1
Atkinson, J; Gayraud, B; Kieffer, P; Lartaud-Idjouadiene, I; Marque, V; Ramirez, F1
Gosling, M; Moss, I; Norman, P; Powell, J; Sian, M1
Baccarani Contri, M; Bacchelli, B; Biagini, G; Miselli, M; Taparelli, F1
Fujimura, T; Fukuchi, Y; Kaga, N; Murayama, K; Seyama, K; Soma, S1
Abe, M; Horiuchi, K; Nagano, A; Takahashi, M1
Lieberman, S; Lin, YY; Ma, S; Turino, GM1
Getie, M; Neubert, RH; Raith, K1
Cantor, JO; Shteyngart, B1
Cantor, JO; Cerreta, JM; Chow, T; Grunig, G; Ma, S; Ochoa, M; Turino, GM1
Cantor, JO; Cerreta, JM; Ma, S; Shteyngart, B; Turino, GM1
Allsop, T; Choudhury, SD; Norris, GE; Passman, A1
Annovazzi, L; Casado, B; Iadarola, P; Luisetti, M; Stolk, J; Viglio, S1
Atsawasuwan, P; Katafuchi, M; Matsuura, T; Sato, H; Yamauchi, M1
Lin, YY; Ma, S; Turino, GM2
Huang, J; Kang, J1
Casado, B; Iadarola, P; Lin, YY; Luisetti, M; Ma, S; Snider, GL; Stone, PJ; Turino, GM; Viglio, S1
Bateman, KP; Berthelette, C; Boutin, M; Gervais, FG; Hoidal, J; Leppert, MF; Scholand, MB; Thibault, P1
Lin, YY; Ma, S; Tartell, L; Turino, GM1
Barr, ML; Bjarnsholt, T; Döring, G; Friedel, G; Geiser, M; Gulbins, E; Iadarola, P; Meyer, KC; Pier, GB; Ratjen, F; Schuster, A; Shute, JK; Siegmann, N; Ulrich, M; Viglio, S; Worlitzsch, D1
Albarbarawi, O; Barton, A; Brady, J; Buddharaju, A; Huang, JT; Lin, Z; Miller, D; Palmer, CN; Takahashi, E1
Hashimoto, Y; Iba, K; Matsumoto, A; Matsuzaki, K; Shiraishi, K1
Cantor, JO; Cerreta, JM; Liu, M; Ma, S; Ochoa, M; Turino, GM1
He, J; Lin, YY; Ma, S; Robbins, RA; Slowik, N; Soldin, OP; Turino, GM1
Aikawa, M; Libby, P; Umeda, H1
Cantor, JO; Lin, YY; Luisetti, M; Ma, S; Turino, GM1
Ferrari, F; Fregonese, L; Fumagalli, M; Iadarola, P; Luisetti, M; Stolk, J1
Gryszczyńska, A; Jakubowski, H; Mielcarek, S; Perła-Kaján, J1
Anderson, M; de Verdier, MG; Engström, G; Forsman-Semb, K; Lindberg, CA; Nihlén, U; Svartengren, M1
Di Donato, A; Oleggini, R1
Cook, J; Creaser, CS; Devenport, NA; Parkash, V; Reynolds, JC; Weston, DJ1
Iadarola, P; Luisetti, M; Stolk, J1
Dekhuijzen, R; Janssen, R; Spanbroek, M1
Cantor, JO; He, J; Lin, YY; Ma, S; Turino, GM1
Elmlinger, M; Ernst, P; Hohlfeld, JM; Holz, O; Krug, N; Lahu, G; Lauer, G; Müller, M; Rittinghausen, S; Röpcke, S1
MacNee, W1
Bischoff, R; Bruins, AP; Hermans, J; Nieuwendijk, AM; Ongay, S; Overkleeft, H1
Cutler, P; Döbeli, H; Friedlein, A; Lamerz, J; Soder, N1
Iadarola, P; Luisetti, M1
Hayashi, T; Lin, YY; Ma, S; Turino, GM; Usuki, T; Yanuma, H1
Albarbarawi, O; Barton, A; Chaudhuri, R; Devereux, G; Huang, JT; McSharry, C; Miller, D; Palmer, CN; Thomson, NC1
Bamba, M; Hirota, T; Miyajima, A; Muto, T1
Hirota, T; Miyajima, A; Muto, T; Okamoto, M1
Bischoff, R; Hendriks, G; Hermans, J; Ongay, S; ten Hacken, NH; van de Merbel, NC; van den Berge, M1
Komatsu, A; Koseki, Y; Sugimura, T; Usuki, T1
Heinz, A; Majovsky, P; Schmelzer, CE; Schräder, CU1
Cantor, J; Liu, M; Liu, S; Liu, X; Ma, S; Turino, G1
Hill, JE; Kato, J; Sampedro, I1
Komatsu, A; Tanigawa, T; Usuki, T1
Cantor, JO; Lin, YY; Ma, S; Turino, GM2
Bolton, CE; Huang, JT; MacNee, W; Miller, BE; Palmer, CN; Rabinovich, RA; Tal-Singer, R; Thomson, NC1
Cantor, J; Liu, X; Ma, S; Turino, G1
Kim, C; Kim, SH; Kim, TH; Ko, Y; Lee, JH; Lee, JS; Lee, SD; Lim, SY; Oh, YM; Park, YB; Rhee, CK; Seo, JB; Yoo, HJ; Yoo, KH1
Janssen, R; Vermeer, C1
Cantor, J; Ma, S; Turino, G1
Turino, GM1
Avella, J; Cantor, J; Fagiola, M; Gu, G1
Chick, CN; Kawaguchi, M; Niikura, T; Sasaki, Y; Tanaka, E; Usuki, T1

Reviews

9 review(s) available for isodesmosine and desmosine

ArticleYear
Synthesis of connective tissue macromolecules by smooth muscle.
    International review of connective tissue research, 1979, Volume: 8

    Topics: Animals; Cells, Cultured; Collagen; Connective Tissue; Desmosine; Elastic Tissue; Elastin; Fibroblasts; Glycosaminoglycans; Isodesmosine; Microscopy, Electron; Muscle, Smooth; Organ Culture Techniques; Proteoglycans

1979
Potential use of collagen and elastin degradation markers for monitoring liver fibrosis in schistosomiasis.
    Acta tropica, 2000, Oct-23, Volume: 77, Issue:1

    Topics: Amino Acids; Animals; Biomarkers; Collagen; Desmosine; Elastin; Humans; Isodesmosine; Liver Cirrhosis; Schistosomiasis

2000
How a test for elastic fiber breakdown products in sputum could speed development of a treatment for pulmonary emphysema.
    Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:1

    Topics: Desmosine; Elastic Tissue; Elastin; Humans; Isodesmosine; Pulmonary Emphysema; Sputum

2004
Progress in the methodological strategies for the detection in real samples of desmosine and isodesmosine, two biological markers of elastin degradation.
    Journal of separation science, 2007, Volume: 30, Issue:2

    Topics: Amino Acids; Animals; Biomarkers; Desmosine; Elastin; Humans; Immunochemistry; Isodesmosine

2007
Matrix elastin: a promising biomarker for chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2011, Sep-15, Volume: 184, Issue:6

    Topics: Biomarkers; Desmosine; Elastin; Humans; Isodesmosine; Lung; Peptide Hydrolases; Pulmonary Disease, Chronic Obstructive; Sputum

2011
Elastin degradation: an effective biomarker in COPD.
    COPD, 2012, Volume: 9, Issue:4

    Topics: Biomarkers; Bronchodilator Agents; Chromatography, High Pressure Liquid; Desmosine; Disease Progression; Drug Monitoring; Elastin; Humans; Isodesmosine; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Tandem Mass Spectrometry

2012
Systemic inflammatory biomarkers and co-morbidities of chronic obstructive pulmonary disease.
    Annals of medicine, 2013, Volume: 45, Issue:3

    Topics: Adiponectin; Aging; Airway Remodeling; Biomarkers; C-Reactive Protein; Cachexia; Cardiovascular Diseases; CD40 Ligand; Chemokines, CC; Cytokines; Desmosine; Fibrinogen; Humans; Inflammation; Intercellular Adhesion Molecule-1; Isodesmosine; Lung Neoplasms; Matrix Metalloproteinases; Natriuretic Peptide, Brain; Osteoprotegerin; Pulmonary Disease, Chronic Obstructive; Pulmonary Surfactant-Associated Protein D; Serum Amyloid A Protein; Severity of Illness Index; Telomere; Uteroglobin

2013
The role of desmosines as biomarkers for chronic obstructive pulmonary disease.
    Expert review of respiratory medicine, 2013, Volume: 7, Issue:2

    Topics: Animals; Biomarkers; Desmosine; Elastic Tissue; Humans; Isodesmosine; Lung; Predictive Value of Tests; Prognosis; Pulmonary Disease, Chronic Obstructive

2013
Biomarkers in Alpha-1 Antitrypsin Deficiency Chronic Obstructive Pulmonary Disease.
    Annals of the American Thoracic Society, 2016, Volume: 13 Suppl 4

    Topics: alpha 1-Antitrypsin Deficiency; Biomarkers; Desmosine; Elastin; Fibrinogen; Humans; Isodesmosine; Leukocyte Elastase; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Uteroglobin

2016

Trials

2 trial(s) available for isodesmosine and desmosine

ArticleYear
Determination of free desmosine in human plasma and its application in two experimental medicine studies.
    Analytical biochemistry, 2013, May-15, Volume: 436, Issue:2

    Topics: Adult; Age Factors; Aged; Biomarkers; Body Mass Index; Body Weight; Case-Control Studies; Chemical Precipitation; Chromatography, High Pressure Liquid; Desmosine; Deuterium; Female; Humans; Isodesmosine; Male; Mass Spectrometry; Middle Aged; Pulmonary Disease, Chronic Obstructive; Reference Values; Reproducibility of Results; Russia; Smoking; United States

2013
A pilot clinical trial to determine the safety and efficacy of aerosolized hyaluronan as a treatment for COPD.
    International journal of chronic obstructive pulmonary disease, 2017, Volume: 12

    Topics: Administration, Inhalation; Adult; Aerosols; Aged; Arizona; Biomarkers; Desmosine; Double-Blind Method; Elastin; Humans; Hyaluronic Acid; Isodesmosine; Lung; Middle Aged; New York City; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Sputum; Time Factors; Treatment Outcome

2017

Other Studies

129 other study(ies) available for isodesmosine and desmosine

ArticleYear
Photolysis of desmosine and isodesmosine by ultraviolet light.
    European journal of biochemistry, 1976, Aug-01, Volume: 67, Issue:1

    Topics: Amino Acids; Animals; Cattle; Desmosine; Elastin; Hydrogen-Ion Concentration; Isodesmosine; Ligaments; Magnetic Resonance Spectroscopy; Photolysis; Spectrophotometry, Ultraviolet; Ultraviolet Rays

1976
Studies on cross-linked regions of elastin.
    Advances in experimental medicine and biology, 1977, Volume: 86B

    Topics: Amino Acids; Chemical Phenomena; Chemistry; Desmosine; Elastin; Hydrogen-Ion Concentration; Isodesmosine; Lysine; Peptide Fragments

1977
Lysyl oxidase deficiency in lung and fibroblasts from mice with hereditary emphysema.
    Biochemical and biophysical research communications, 1977, Sep-23, Volume: 78, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Desmosine; Female; Fibroblasts; Genetic Linkage; Isodesmosine; Lung; Mice; Muscles; Protein-Lysine 6-Oxidase; Pulmonary Emphysema; X Chromosome

1977
Influence of D-penicillamine on the formation of elastin and its cross-links.
    Physiologia Bohemoslovaca, 1978, Volume: 27, Issue:6

    Topics: Amino Acids; Animals; Animals, Newborn; Aorta; Chick Embryo; Desmosine; Elastin; Isodesmosine; Mice; Penicillamine

1978
Collagen, elastin and desmosines in three layers of bovine aortas of different ages.
    Experimental gerontology, 1979, Volume: 14, Issue:1

    Topics: Aging; Amino Acids; Animals; Aorta, Thoracic; Cattle; Collagen; Desmosine; Elastin; Female; Isodesmosine

1979
Studies on the absorption of desmosine and isodesmosine.
    The Journal of laboratory and clinical medicine, 1979, Volume: 94, Issue:6

    Topics: Amino Acids; Animals; Cricetinae; Desmosine; Dogs; Elastin; Extracellular Space; Injections, Intraperitoneal; Intestinal Absorption; Intubation, Gastrointestinal; Isodesmosine; Lysine; Male; Norleucine; Rabbits; Valine

1979
Considerations of aortic elastin chemistry in the genesis of the intimal plaque (broad-breasted white turkey).
    Experimental and molecular pathology, 1979, Volume: 31, Issue:3

    Topics: Aging; Amino Acids; Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Collagen; Desmosine; Elastin; Female; Isodesmosine; Male; Turkeys

1979
Dihydropyridine precursors of elastin crosslinks.
    Biochimica et biophysica acta, 1978, Jan-18, Volume: 538, Issue:2

    Topics: Amino Acids; Animals; Cattle; Desmosine; Elastin; Isodesmosine; Oxidation-Reduction; Protein Precursors; Spectrophotometry, Ultraviolet

1978
Elastin content of the scleral spur, trabecular mesh, and sclera.
    Investigative ophthalmology & visual science, 1978, Volume: 17, Issue:8

    Topics: Collagen; Desmosine; Elastin; Humans; Hydroxyproline; Isodesmosine; Sclera; Trabecular Meshwork

1978
A molecular basis for elastic tissue degeneration in pulmonary and vascular disease.
    The Alabama journal of medical sciences, 1978, Volume: 15, Issue:4

    Topics: Desmosine; Elastic Tissue; Elasticity; Elastin; Humans; Isodesmosine; Lung Diseases; Models, Biological; Models, Molecular; Proline; Vascular Diseases

1978
Determination of the elastin content of tissues by measuring desmosine and isodesmosine.
    Analytical biochemistry, 1977, May-01, Volume: 79, Issue:1-2

    Topics: Amino Acids; Animals; Cattle; Cricetinae; Desmosine; Elastin; Female; Humans; Isodesmosine; Lung; Rats; Skin; Swine; Uterus

1977
A large scale procedure for purification of desmosine and isodesmosine.
    Preparative biochemistry, 1975, Volume: 5, Issue:5-6

    Topics: Amino Acids; Animals; Cattle; Chromatography, Ion Exchange; Desmosine; Elastin; Isodesmosine; Ligaments

1975
Elastin content, cross-links, and mRNA in normal and aneurysmal human aorta.
    Journal of vascular surgery, 1992, Volume: 16, Issue:2

    Topics: Aged; Amino Acid Sequence; Aorta, Abdominal; Aortic Aneurysm; Blotting, Northern; Chromatography, High Pressure Liquid; Desmosine; Elastin; Humans; Isodesmosine; Linear Models; Molecular Sequence Data; RNA, Messenger; Thermolysin

1992
High-performance liquid chromatographic determination of desmosine and isodesmosine after phenylisothiocyanate derivatization.
    Journal of chromatography, 1991, Dec-06, Volume: 572, Issue:1-2

    Topics: Animals; Aorta; Chromatography, High Pressure Liquid; Desmosine; Humans; Isodesmosine; Isothiocyanates; Lung; Male; Rats; Spectrophotometry, Ultraviolet; Thiocyanates; Veins

1991
Measurement of urinary desmosine by isotope dilution and high performance liquid chromatography. Correlation between elastase-induced air-space enlargement in the hamster and elevation of urinary desmosine.
    The American review of respiratory disease, 1991, Volume: 144, Issue:2

    Topics: Adult; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cricetinae; Desmosine; Enzyme-Linked Immunosorbent Assay; Humans; Isodesmosine; Male; Pancreatic Elastase; Pulmonary Emphysema; Radioimmunoassay; Radioisotope Dilution Technique; Reference Values

1991
Silica gel high-performance liquid chromatography for the determination of cross-links in elastin.
    Journal of chromatographic science, 1991, Volume: 29, Issue:5

    Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cross-Linking Reagents; Desmosine; Elastin; Female; Isodesmosine; Molecular Sequence Data; Spectrophotometry, Ultraviolet

1991
The effect of 60% oxygen on air-space enlargement and cross-linked elastin synthesis in hamsters with elastase-induced emphysema.
    The American review of respiratory disease, 1990, Volume: 142, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Cross-Linking Reagents; Desmosine; Elastin; Isodesmosine; Lung; Lysine; Mesocricetus; Oxygen; Pancreatic Elastase; Pulmonary Emphysema

1990
Determination of desmosines in elastin-related skin disorders by isocratic high-performance liquid chromatography.
    Experimental and molecular pathology, 1990, Volume: 52, Issue:1

    Topics: Adult; Aged; Amino Acids; Chromatography, High Pressure Liquid; Cutis Laxa; Desmosine; Elastin; Humans; Isodesmosine; Middle Aged; Pseudoxanthoma Elasticum; Skin; Skin Diseases

1990
Development and validation of a high-performance liquid chromatographic method for the determination of desmosines in tissues.
    Journal of chromatography, 1990, May-16, Volume: 507

    Topics: Amino Acids; Animals; Aorta; Chromatography, High Pressure Liquid; Desmosine; Elastin; Isodesmosine; Liver; Lung; Rabbits; Rats

1990
The collagenous protein with elastin crosslinks from Descemet's membrane is not related to type VIII collagen.
    Biochemical and biophysical research communications, 1990, Aug-31, Volume: 171, Issue:1

    Topics: Amino Acids; Animals; Collagen; Cyanogen Bromide; Descemet Membrane; Desmosine; Elastin; Isodesmosine; Molecular Weight; Peptide Mapping; Phenol; Phenols; Sheep; Solubility

1990
An enzyme-linked immunosorbent assay (ELISA) for the quantitation of urinary desmosine.
    The Tokai journal of experimental and clinical medicine, 1989, Volume: 14, Issue:4

    Topics: Air Pollutants; Cross Reactions; Desmosine; Elastin; Enzyme-Linked Immunosorbent Assay; Humans; Hydrolysis; Isodesmosine; Lung; Lung Injury; Smoking

1989
Determination of desmosine, isodesmosine, and other amino acids by liquid chromatography with electrochemical detection following precolumn derivatization with naphthalenedialdehyde/cyanide.
    Analytical biochemistry, 1989, Volume: 178, Issue:1

    Topics: Aldehydes; Amino Acids; Chromatography, High Pressure Liquid; Desmosine; Elastin; Electrochemistry; Indoles; Isodesmosine; Naphthalenes; Nitriles; Time Factors

1989
The biochemical composition of hemodynamically stressed vascular tissue: the insoluble elastin of experimental arteriovenous fistulae.
    Experimental and molecular pathology, 1989, Volume: 51, Issue:2

    Topics: Amino Acids; Animals; Arteriovenous Fistula; Carotid Arteries; Cholesterol; Desmosine; Elastin; Isodesmosine; Jugular Veins; Lipids; Sheep

1989
Stimulation of lung lysyl oxidase activity in hamsters with elastase-induced emphysema.
    The American review of respiratory disease, 1985, Volume: 131, Issue:1

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Cricetinae; Desmosine; Emphysema; Female; Isodesmosine; Lung; Lysine; Mesocricetus; Pancreatic Elastase; Protein-Lysine 6-Oxidase

1985
Impairment of elastin resynthesis in the lungs of hamsters with experimental emphysema induced by sequential administration of elastase and trypsin.
    The Journal of laboratory and clinical medicine, 1985, Volume: 105, Issue:2

    Topics: Animals; Chymotrypsin; Cricetinae; Desmosine; Disease Models, Animal; Elastin; Female; Isodesmosine; Lung; Lysine; Mesocricetus; Pancreatic Elastase; Protein-Lysine 6-Oxidase; Pulmonary Emphysema; Trypsin

1985
Photolysis and ozonolysis of desmosine and elastolytic peptides.
    Connective tissue research, 1985, Volume: 14, Issue:2

    Topics: Amino Acids; Animals; Cattle; Chromatography, Gel; Desmosine; Elastin; In Vitro Techniques; Isodesmosine; Molecular Weight; Ozone; Peptide Fragments; Photolysis; Protein Conformation

1985
Rapid method for determining desmosine, isodesmosine, 5-hydroxylysine, tryptophan, lysinoalanine and the amino sugars in proteins and tissues.
    Journal of chromatography, 1986, May-28, Volume: 378, Issue:1

    Topics: Amino Acids; Amino Sugars; Chromatography, Ion Exchange; Desmosine; Humans; Hydroxylysine; Isodesmosine; Lysine; Lysinoalanine; Proteins; Stereoisomerism; Tryptophan

1986
High-performance liquid chromatographic quantitation of desmosine plus isodesmosine in elastin and whole tissue hydrolysates.
    Analytical biochemistry, 1987, Volume: 160, Issue:1

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Desmosine; Elastin; Hydrolysis; Isodesmosine; Lysine; Tritium

1987
Photolysis and partial ozonolysis of kappa-elastin from ligamentum nuchae.
    Connective tissue research, 1985, Volume: 13, Issue:3

    Topics: Amino Acid Sequence; Animals; Cattle; Desmosine; Elastin; Isodesmosine; Ligaments; Ozone; Peptide Fragments; Photolysis

1985
[Biosynthesis of insoluble elastin in the chicken aorta].
    Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 1988, Volume: 31, Issue:4

    Topics: Animals; Aorta; Chick Embryo; Desmosine; Elastin; Isodesmosine; Solubility

1988
High-performance liquid chromatographic determination of desmosine and isodesmosine in tissues and its application to studies of alteration of elastin induced by atherosclerosis.
    Journal of chromatography, 1987, Nov-27, Volume: 422

    Topics: Amino Acids; Animals; Arteriosclerosis; Chromatography, High Pressure Liquid; Desmosine; Diet, Atherogenic; Elastin; Hydrogen-Ion Concentration; Isodesmosine; Liver; Lung; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains

1987
Desmosine and isodesmosine as cross-links in the hinge-ligament protein of bivalves. 3,3'-Methylenebistyrosine as an artefact.
    European journal of biochemistry, 1987, Apr-15, Volume: 164, Issue:2

    Topics: Amino Acids; Animals; Bivalvia; Cross-Linking Reagents; Desmosine; Isodesmosine; Ligaments; Protein Conformation; Proteins; Tyrosine

1987
Photolysis and ozonolysis of (iso)desmosine-containing crosslinked peptides from porcine aorta elastin.
    International journal of peptide and protein research, 1987, Volume: 29, Issue:1

    Topics: Amino Acids; Animals; Aorta; Chemical Phenomena; Chemistry; Desmosine; Elastin; Isodesmosine; Ozone; Peptide Fragments; Photolysis; Swine

1987
Elastase digestion and biochemical analysis of the elastin from an elastofibroma.
    Cancer, 1986, Sep-01, Volume: 58, Issue:5

    Topics: Aged; Amino Acids; Desmosine; Dipeptides; Elastin; Female; Fibroma; Humans; Isodesmosine; Microscopy, Electron; Pancreas; Pancreatic Elastase; Shoulder; Skin Neoplasms

1986
Cigarette smoke impairs elastin resynthesis in lungs of hamsters with elastase-induced emphysema.
    The American review of respiratory disease, 1985, Volume: 132, Issue:3

    Topics: Animals; Cricetinae; Desmosine; Elastin; Female; Isodesmosine; Lung; Lysine; Mesocricetus; Nicotiana; Pancreatic Elastase; Plants, Toxic; Pulmonary Emphysema; Smoke

1985
Synthesis of crosslinked elastin by a mesothelial cell culture.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 181, Issue:3

    Topics: Autoradiography; Cells, Cultured; Desmosine; Elastin; Humans; Isodesmosine; Pleura; Serous Membrane

1986
Sulfated glycopeptides, containing desmosine and isodesmosine, isolated from porcine aorta.
    The Tohoku journal of experimental medicine, 1985, Volume: 145, Issue:2

    Topics: Amino Acids; Animals; Aorta, Thoracic; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Clusterin; Desmosine; Glycoproteins; Isodesmosine; Male; Molecular Chaperones; Swine

1985
Altered urinary excretion of elastin cross-links in premature infants who develop bronchopulmonary dysplasia.
    The American review of respiratory disease, 1985, Volume: 131, Issue:4

    Topics: Age Factors; Bronchopulmonary Dysplasia; Desmosine; Elastin; Humans; Infant, Newborn; Infant, Premature, Diseases; Isodesmosine; Male; Oxygen Inhalation Therapy

1985
Content of the collagen and elastin cross-links pyridinoline and the desmosines in the human uterus in various reproductive states.
    American journal of obstetrics and gynecology, 1985, Sep-01, Volume: 153, Issue:1

    Topics: Amino Acids; Collagen; Connective Tissue; Desmosine; Elastin; Female; Humans; In Vitro Techniques; Isodesmosine; Postpartum Period; Pregnancy; Pyridines; Reproduction; Uterus

1985
Localization of lysyl oxidase in hen oviduct: implications in egg shell membrane formation and composition.
    Science (New York, N.Y.), 1980, Apr-04, Volume: 208, Issue:4439

    Topics: Amino Acid Oxidoreductases; Animals; Chickens; Copper; Cross-Linking Reagents; Desmosine; Egg Shell; Isodesmosine; Oviducts; Protein-Lysine 6-Oxidase

1980
Antigenicity of human lung elastin peptides.
    Bulletin europeen de physiopathologie respiratoire, 1980, Volume: 16 Suppl

    Topics: Animals; Chromatography, Gel; Desmosine; Elastin; Epitopes; Guinea Pigs; Humans; Immunoelectrophoresis; Isodesmosine; Papain; Peptides; Pulmonary Emphysema; Rabbits

1980
Measurement of cross-linked elastin synthesis in bleomycin-induced pulmonary fibrosis using a highly sensitive assay for desmosine and isodesmosine.
    The Journal of laboratory and clinical medicine, 1984, Volume: 103, Issue:3

    Topics: Amino Acids; Animals; Bleomycin; Carbon Radioisotopes; Cricetinae; Desmosine; Elastin; Female; Isodesmosine; Lysine; Mesocricetus; Pulmonary Fibrosis

1984
Influence of D-penicillamine and iproniazid on the formation of cross-links in elastin.
    Physiologia Bohemoslovaca, 1980, Volume: 29, Issue:4

    Topics: Animals; Aorta; Chick Embryo; Desmosine; Elastin; Iproniazid; Isodesmosine; Penicillamine

1980
The presence of desmosine and isodesmosine in eggshell membrane protein.
    Connective tissue research, 1980, Volume: 8, Issue:1

    Topics: Amino Acids; Animals; Chickens; Desmosine; Egg Shell; Female; Isodesmosine; Membrane Proteins; Radioimmunoassay

1980
Effects of extracellular matrix upon elastogenesis.
    Connective tissue research, 1981, Volume: 8, Issue:3-4

    Topics: Animals; Cattle; Cells, Cultured; Desmosine; Elastin; Female; Fetus; Fibroblasts; Gestational Age; Isodesmosine; Ligaments; Lysine; Pregnancy

1981
Separation of elastin components by thin layer chromatography and electrophoresis.
    Connective tissue research, 1981, Volume: 8, Issue:3-4

    Topics: Amino Acids; Animals; Chromatography, Thin Layer; Desmosine; Elastin; Electrophoresis, Paper; Isodesmosine; Ligaments

1981
Elevation of histidinoalanine in calcified human aortas.
    Biochemistry international, 1984, Volume: 8, Issue:4

    Topics: Amino Acids; Aorta; Arteriosclerosis; Calcinosis; Cross-Linking Reagents; Desmosine; Dipeptides; Humans; Isodesmosine

1984
A rapid sensitive assay for the quantitation of elastin.
    Connective tissue research, 1984, Volume: 12, Issue:3-4

    Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desmosine; Dipeptides; Elastin; Electrophoresis, Paper; Hydrolysis; Isodesmosine; Microchemistry; Muscle, Smooth; Myocardium; Rats

1984
Desmosine and isodesmosine contents and elastase activity in normal and cirrhotic rat liver.
    The Biochemical journal, 1983, Sep-15, Volume: 214, Issue:3

    Topics: Amino Acids; Animals; Desmosine; Female; Isodesmosine; Liver; Liver Cirrhosis, Experimental; Pancreatic Elastase; Rats; Rats, Inbred Strains; Substrate Specificity

1983
Isolation and characterization of salt-soluble cross-linked elastin from vascular tissue.
    Angiology, 1984, Volume: 35, Issue:1

    Topics: Amino Acids; Animals; Arteriovenous Shunt, Surgical; Carotid Arteries; Chromatography; Desmosine; Elastin; Electrophoresis, Polyacrylamide Gel; Isodesmosine; Jugular Veins; Sheep; Sodium Dodecyl Sulfate

1984
Aging and cross-linking in human aorta.
    Biochemical and biophysical research communications, 1982, Dec-31, Volume: 109, Issue:4

    Topics: Aged; Aging; Amino Acids; Aorta; Chromatography, High Pressure Liquid; Desmosine; Dipeptides; Humans; Isodesmosine; Peptide Fragments; Peptide Hydrolases; Proteins

1982
Conclusive evidence for the presence of elastin in human and monkey cervix.
    American journal of obstetrics and gynecology, 1982, Jan-15, Volume: 142, Issue:2

    Topics: Adult; Animals; Cervix Uteri; Desmosine; Elastin; Female; Histocytochemistry; Humans; Isodesmosine; Macaca; Macaca mulatta; Macaca nemestrina; Microscopy, Electron; Pregnancy

1982
Liquid-chromatographic measurement of elastin.
    Clinical chemistry, 1982, Volume: 28, Issue:7

    Topics: Animals; Aorta; Chromatography, High Pressure Liquid; Desmosine; Dogs; Elastin; Female; Humans; Hydrogen-Ion Concentration; Isodesmosine; Male; Reference Values

1982
Rapid method for the purification of the elastin cross-links, desmosine and isodesmosine.
    Journal of chromatography, 1982, Apr-16, Volume: 229, Issue:1

    Topics: Amino Acids; Animals; Chromatography, Thin Layer; Desmosine; Elastin; Isodesmosine; Lung; Radioimmunoassay; Sheep

1982
Mature bovine Descemet's membrane contains desmosine and isodesmosine.
    Biochemical and biophysical research communications, 1982, Oct-29, Volume: 108, Issue:4

    Topics: Amino Acids; Animals; Basement Membrane; Cattle; Descemet Membrane; Desmosine; Isodesmosine

1982
Lung elastin content in normal and emphysematous lungs.
    Bulletin europeen de physiopathologie respiratoire, 1980, Volume: 16 Suppl

    Topics: Adult; Aged; Animals; Desmosine; Dogs; Elastin; Female; Humans; Isodesmosine; Lung; Male; Middle Aged; Papain; Pulmonary Emphysema; Rats

1980
Amino acid analysis of elastin hydrolysates using a lithium citrate gradient: quantification of elastin from whole lung.
    Clinica chimica acta; international journal of clinical chemistry, 1981, Mar-05, Volume: 110, Issue:2-3

    Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Citrates; Citric Acid; Cricetinae; Desmosine; Elastin; Humans; Isodesmosine; Lithium; Lung; Mesocricetus

1981
Egg shell membrane protein: a nonelastin desmosine/isodesmosine-containing protein.
    Archives of biochemistry and biophysics, 1981, Apr-01, Volume: 207, Issue:2

    Topics: Amino Acids; Animals; Chickens; Desmosine; Egg Proteins; Egg Shell; Elastin; Isodesmosine; Membrane Proteins

1981
Elastin content of normal and emphysematous lung parenchyma.
    The American journal of medicine, 1980, Volume: 69, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Aged; Amino Acids; Desmosine; Elastin; Female; Humans; Isodesmosine; Lung; Male; Middle Aged; Pulmonary Emphysema; Respiratory Function Tests

1980
Enrichment and analysis of desmosine and isodesmosine in biological fluids.
    Journal of chromatography. B, Biomedical applications, 1995, Jun-23, Volume: 668, Issue:2

    Topics: Animals; Body Fluids; Chromatography, High Pressure Liquid; Cricetinae; Desmosine; Humans; Isodesmosine; Lung; Reference Values; Reproducibility of Results; Spectrophotometry, Ultraviolet

1995
Elastin and collagen degradation products in urine of patients with cystic fibrosis.
    American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:1

    Topics: Adult; Amino Acids; Bronchoalveolar Lavage Fluid; Case-Control Studies; Collagen; Cystic Fibrosis; Desmosine; Elastin; Female; Humans; Isodesmosine; Leukocyte Elastase; Male; Neutrophils; Pancreatic Elastase; Receptors, Complement

1995
Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:4

    Topics: Adult; Amino Acids; Biomarkers; Collagen; Desmosine; Elastin; Female; Humans; Isodesmosine; Lung Diseases, Obstructive; Male; Middle Aged; Prospective Studies; Smoking

1995
Cross-linked elastin and collagen degradation products in the urine of patients with scleroderma.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:4

    Topics: Adult; Aged; Amino Acids; Collagen; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Middle Aged; Reference Values; Scleroderma, Systemic

1995
Preliminary evidence that augmentation therapy diminishes degradation of cross-linked elastin in alpha-1-antitrypsin-deficient humans.
    Respiration; international review of thoracic diseases, 1995, Volume: 62, Issue:2

    Topics: Adult; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Amino Acids; Bronchiectasis; Desmosine; Elastin; Emphysema; Female; Humans; Isodesmosine; Lung; Male; Middle Aged; Smoking

1995
Effect of diet on urinary excretion of desmosine and hydroxylysyl pyridinoline.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Amino Acids; Analysis of Variance; Animals; Bias; Biomarkers; Cattle; Chromatography, High Pressure Liquid; Collagen; Creatinine; Desmosine; Diet; Dietary Proteins; Elastin; Humans; Isodesmosine; Male; Meat; Reproducibility of Results

1994
Alteration of elastin in aorta from diabetics.
    Atherosclerosis, 1993, Volume: 101, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Cholesterol; Chromatography, High Pressure Liquid; Desmosine; Diabetes Mellitus; Elastin; Female; Humans; Hydroxyproline; Isodesmosine; Male; Middle Aged

1993
Comparison of ELISA and HPLC for the determination of desmosine or isodesmosine in aortic tissue elastin.
    Journal of clinical laboratory analysis, 1995, Volume: 9, Issue:5

    Topics: Animals; Aorta; Binding, Competitive; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Desmosine; Elastin; Enzyme-Linked Immunosorbent Assay; Female; Isodesmosine; Rabbits; Reproducibility of Results

1995
Biochemical assay of collagen and elastin in the normal and varicose vein wall.
    The Journal of surgical research, 1996, Volume: 60, Issue:1

    Topics: Adult; Aged; Biochemistry; Collagen; Desmosine; Elastin; Female; Humans; Hydroxyproline; Isodesmosine; Male; Middle Aged; Muscle, Smooth, Vascular; Reference Values; Ultrasonography, Doppler, Color; Varicose Veins; Veins

1996
Calcification of medial elastic fibers and aortic elasticity.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:4

    Topics: Analysis of Variance; Animals; Aorta; Blood Pressure; Calcinosis; Calcium; Desmosine; Elastic Tissue; Elasticity; Electrophoresis; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Isodesmosine; Linear Models; Male; Nicotine; Rats; Spectrophotometry, Atomic; Tunica Media; Vitamin D

1997
Age-related alteration of cross-linking amino acids of elastin in human aorta.
    The Tohoku journal of experimental medicine, 1996, Volume: 180, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Aorta, Thoracic; Autopsy; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Desmosine; Elasticity; Elastin; Humans; Infant; Infant, Newborn; Isodesmosine; Middle Aged; Muscle Development; Muscle, Smooth, Vascular; Piperidines; Pyridines

1996
Distribution of elastin in hamsters and the turnover rates of different elastin pools.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 215, Issue:1

    Topics: Aging; Animals; Aorta; Cricetinae; Desmosine; Elastin; Isodesmosine; Kinetics; Lung; Skin

1997
Biochemical markers of upper esophageal sphincter compliance in patients with Zenker's diverticulum.
    The Journal of surgical research, 1997, Volume: 70, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers; Chromatography, High Pressure Liquid; Collagen; Desmosine; Elastin; Esophagogastric Junction; Esophagus; Female; Humans; Hydroxyproline; Isodesmosine; Male; Manometry; Middle Aged; Muscles; Zenker Diverticulum

1997
Epitope specificity of monoclonal and polyclonal antibodies to human elastin.
    International archives of allergy and immunology, 1998, Volume: 115, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Desmosine; Elastin; Epitope Mapping; Epitopes; Exons; Humans; Immunohistochemistry; Isodesmosine; Isomerism; Molecular Sequence Data; Muscle, Smooth; Peptides; Tropoelastin

1998
Circadian variation of urinary excretion of elastin and collagen crosslinks.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1998, Volume: 218, Issue:3

    Topics: Adult; Amino Acids; Biomarkers; Circadian Rhythm; Collagen; Cross-Linking Reagents; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Middle Aged; Reference Values; Sex Characteristics

1998
Micellar electrokinetic chromatography for the determination of urinary desmosine and isodesmosine in patients affected by chronic obstructive pulmonary disease.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Aug-28, Volume: 714, Issue:1

    Topics: Biomarkers; Chromatography, Micellar Electrokinetic Capillary; Desmosine; Humans; Isodesmosine; Lung Diseases, Obstructive; Spectrophotometry, Ultraviolet

1998
MEKC of desmosine and isodesmosine in urine of chronic destructive lung disease patients.
    The European respiratory journal, 2000, Volume: 15, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; alpha 1-Antitrypsin Deficiency; Bronchiectasis; Cross-Linking Reagents; Cross-Sectional Studies; Cystic Fibrosis; Desmosine; Elastin; Electrophoresis, Capillary; Emphysema; Extracellular Matrix; Female; Humans; Isodesmosine; Longitudinal Studies; Lung Diseases, Obstructive; Male; Middle Aged

2000
Comparison of urinary desmosine excretion in patients with chronic obstructive pulmonary disease or cystic fibrosis.
    Pulmonary pharmacology & therapeutics, 2000, Volume: 13, Issue:4

    Topics: Biomarkers; Case-Control Studies; Child; Cystic Fibrosis; Desmosine; Female; Humans; Isodesmosine; Leukocyte Elastase; Lung Diseases, Obstructive; Male; Middle Aged

2000
Mechanism of formation of elastin crosslinks.
    Connective tissue research, 2000, Volume: 41, Issue:2

    Topics: 2-Aminoadipic Acid; Aldehydes; Amino Acids; Butylamines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cross-Linking Reagents; Desmosine; Elastin; Hydrogen-Ion Concentration; Isodesmosine; Lysine; Pyridinium Compounds

2000
DL-penicillamine induced alteration of elastic fibers of periosteum-perichondrium and associated growth inhibition: an experimental study.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2001, Volume: 19, Issue:3

    Topics: Animals; Antirheumatic Agents; Aorta, Thoracic; Chelating Agents; Chickens; Chromatography, High Pressure Liquid; Collagen; Desmosine; Diet; Elastic Tissue; Hydroxylysine; Hydroxyproline; Image Processing, Computer-Assisted; Isodesmosine; Penicillamine; Periosteum; Tibia

2001
Aortic wall mechanics and composition in a transgenic mouse model of Marfan syndrome.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:7

    Topics: Animals; Aorta; Aorta, Thoracic; Blood Pressure; Body Weight; Desmosine; Dilatation, Pathologic; Elastic Tissue; Elasticity; Female; Heart Rate; Isodesmosine; Male; Marfan Syndrome; Mice; Mice, Transgenic

2001
Maternal and postnatal vitamin D ingestion influences rat aortic structure, function and elastin content.
    Cardiovascular research, 2002, Aug-01, Volume: 55, Issue:2

    Topics: Animal Nutritional Physiological Phenomena; Animals; Aorta; Desmosine; Dose-Response Relationship, Drug; Elasticity; Female; Isodesmosine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Organ Culture Techniques; Pancreatic Elastase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Vitamin D

2002
Histomorphometric, biochemical and ultrastructural changes in the aorta of salt-loaded stroke-prone spontaneously hypertensive rats fed a Japanese-style diet.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2003, Volume: 13, Issue:1

    Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Collagen; Desmosine; Diet; Elastin; Endothelium, Vascular; Hydroxylysine; Hydroxyproline; Hypertension; Hypertrophy; Isodesmosine; Japan; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Stroke; Tunica Intima; Tunica Media

2003
Quantification of elastin cross-linking amino acids, desmosine and isodesmosine, in hydrolysates of rat lung by ion-pair liquid chromatography-mass spectrometry.
    Analytical biochemistry, 2003, Jul-01, Volume: 318, Issue:1

    Topics: Animals; Calibration; Chromatography, Liquid; Desmosine; Elastin; Isodesmosine; Lung; Mass Spectrometry; Molecular Structure; Rats

2003
The changes in crosslink contents in tissues after formalin fixation.
    Analytical biochemistry, 2003, Jul-01, Volume: 318, Issue:1

    Topics: Aged; Aged, 80 and over; Amino Acids; Arginine; Cartilage; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Desmosine; Elastin; Formaldehyde; Freezing; Hip Joint; Humans; Isodesmosine; Ligaments; Lysine; Tissue Fixation

2003
The detection and quantitation of free desmosine and isodesmosine in human urine and their peptide-bound forms in sputum.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Oct-28, Volume: 100, Issue:22

    Topics: Adult; Aged; Biomarkers; Creatinine; Desmosine; Female; Humans; Isodesmosine; Male; Mass Spectrometry; Middle Aged; Pulmonary Disease, Chronic Obstructive; Sputum

2003
LC/ESI-MS analysis of two elastin cross-links, desmosine and isodesmosine, and their radiation-induced degradation products.
    Biochimica et biophysica acta, 2003, Dec-05, Volume: 1624, Issue:1-3

    Topics: Chromatography, Liquid; Desmosine; Dose-Response Relationship, Radiation; Isodesmosine; Spectrometry, Mass, Electrospray Ionization; Ultraviolet Rays

2003
Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema.
    Experimental lung research, 2005, Volume: 31, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Inhalation; Aerosols; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Desmosine; Disease Models, Animal; Elastic Tissue; Female; Hyaluronic Acid; Isodesmosine; Lung; Macrophages, Alveolar; Mice; Mice, Inbred DBA; Pulmonary Alveoli; Pulmonary Emphysema; Smoking

2005
Synergistic effect of hydrogen peroxide and elastase on elastic fiber injury in vitro.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:1

    Topics: Animals; Cells, Cultured; Desmosine; Drug Synergism; Elastic Tissue; Extracellular Matrix; Hydrogen Peroxide; Inflammation Mediators; Isodesmosine; Isotope Labeling; Oxidants; Pancreatic Elastase; Pleural Neoplasms; Pulmonary Emphysema; Rats; Time Factors

2006
Use of a proteomics approach to identify favourable conditions for production of good quality lambskin leather.
    Analytical and bioanalytical chemistry, 2006, Volume: 384, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Desmosine; Elastin; Electrophoresis, Gel, Two-Dimensional; Hydrolysis; Isodesmosine; Proteomics; Sensitivity and Specificity; Sheep; Skin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tanning

2006
Biochemical characterization of collagen in alveolar mucosa and attached gingiva of pig.
    Connective tissue research, 2007, Volume: 48, Issue:2

    Topics: Amino Acids; Animals; Collagen Type I; Collagen Type III; Cross-Linking Reagents; Desmosine; Gene Expression Regulation; Gingiva; Isodesmosine; Jaw; Mouth Mucosa; RNA, Messenger; Swine

2007
Measurements of desmosine and isodesmosine by mass spectrometry in COPD.
    Chest, 2007, Volume: 131, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; alpha 1-Antitrypsin Deficiency; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Prognosis; Pulmonary Disease, Chronic Obstructive; Sensitivity and Specificity; Sputum

2007
Separation and measurement of desmosine and isodesmosine in vascular tissue hydrolysates by micellar electrokinetic capillary chromatography with a mixed micelle system.
    Journal of chromatography. A, 2007, Dec-21, Volume: 1175, Issue:2

    Topics: Animals; Aorta, Thoracic; Chromatography, Micellar Electrokinetic Capillary; Desmosine; Isodesmosine; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2007
Desmosine as a biomarker of elastin degradation in COPD: current status and future directions.
    The European respiratory journal, 2008, Volume: 32, Issue:5

    Topics: Adult; alpha 1-Antitrypsin Deficiency; Child; Chromatography, Liquid; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Models, Biological; Peptides; Pulmonary Disease, Chronic Obstructive; Smoking; Tandem Mass Spectrometry

2008
High-sensitivity nanoLC-MS/MS analysis of urinary desmosine and isodesmosine.
    Analytical chemistry, 2009, Mar-01, Volume: 81, Issue:5

    Topics: Chromatography, Liquid; Desmosine; Elastin; Humans; Isodesmosine; Limit of Detection; Mass Spectrometry; Tandem Mass Spectrometry

2009
The effect of tiotropium therapy on markers of elastin degradation in COPD.
    Respiratory research, 2009, Feb-25, Volume: 10

    Topics: Bronchodilator Agents; Desmosine; Elastin; Forced Expiratory Volume; Humans; Isodesmosine; Pancreatic Elastase; Pulmonary Disease, Chronic Obstructive; Scopolamine Derivatives; Smoking Cessation; Tiotropium Bromide; Vital Capacity

2009
Alveolar inflammation in cystic fibrosis.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2010, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Case-Control Studies; Ceramides; Collagen; Cystic Fibrosis; Desmosine; Elastin; Female; Humans; Inflammation; Isodesmosine; Male; Pseudomonas aeruginosa; Pulmonary Alveoli; Young Adult

2010
Measurement of urinary total desmosine and isodesmosine using isotope-dilution liquid chromatography-tandem mass spectrometry.
    Analytical chemistry, 2010, May-01, Volume: 82, Issue:9

    Topics: Chromatography, Liquid; Desmosine; Humans; Isodesmosine; Limit of Detection; Radioisotope Dilution Technique; Reproducibility of Results; Tandem Mass Spectrometry

2010
Development of a robust LC-MS/MS method for determination of desmosine and isodesmosine in human urine.
    Journal of oleo science, 2010, Volume: 59, Issue:8

    Topics: Adult; Calibration; Case-Control Studies; Chromatography, Liquid; Desmosine; Drug Stability; Efficiency; Elastin; Female; Humans; Isodesmosine; Lung Neoplasms; Lymphangioleiomyomatosis; Male; Models, Biological; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Tandem Mass Spectrometry; Urinalysis

2010
Therapeutic effects of hyaluronan on smoke-induced elastic fiber injury: does delayed treatment affect efficacy?
    Lung, 2011, Volume: 189, Issue:1

    Topics: Administration, Inhalation; Aerosols; Animals; Bronchoalveolar Lavage Fluid; Desmosine; Disease Models, Animal; Dose-Response Relationship, Drug; Elastic Tissue; Female; Hyaluronic Acid; Isodesmosine; Lung; Mice; Mice, Inbred DBA; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Smoking; Time Factors

2011
The effect of secondhand smoke exposure on markers of elastin degradation.
    Chest, 2011, Volume: 140, Issue:4

    Topics: Adult; Aged; Biomarkers; Cohort Studies; Cotinine; Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Middle Aged; Nicotine; Pulmonary Disease, Chronic Obstructive; Risk Factors; Smoking; Tobacco Smoke Pollution; Young Adult

2011
Quantitation of desmosine and isodesmosine in urine, plasma, and sputum by LC-MS/MS as biomarkers for elastin degradation.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Jul-01, Volume: 879, Issue:21

    Topics: Amino Acids; Biomarkers; Case-Control Studies; Chromatography, Liquid; Desmosine; Elastin; Humans; Hydrochloric Acid; Hydrolysis; Isodesmosine; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results; Sensitivity and Specificity; Sputum; Tandem Mass Spectrometry

2011
Liberation of desmosine and isodesmosine as amino acids from insoluble elastin by elastolytic proteases.
    Biochemical and biophysical research communications, 2011, Jul-29, Volume: 411, Issue:2

    Topics: Animals; Biomarkers; Cardiovascular Diseases; Cell Line; Desmosine; Elastin; Humans; Isodesmosine; Leukocyte Elastase; Matrix Metalloproteinase 12; Mice; Reactive Oxygen Species; Recombinant Proteins

2011
Long-term variability of desmosine/isodesmosine as biomarker in alpha-1-antritrypsin deficiency-related COPD.
    COPD, 2011, Volume: 8, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; alpha 1-Antitrypsin; Biomarkers; Desmosine; Female; Forced Expiratory Volume; Humans; Isodesmosine; Male; Middle Aged; Pulmonary Emphysema; Time Factors

2011
Cation exchange HPLC analysis of desmosines in elastin hydrolysates.
    Analytical and bioanalytical chemistry, 2011, Volume: 401, Issue:8

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Desmosine; Elastin; Hyperhomocysteinemia; Isodesmosine; Limit of Detection; Lung; Male; Mice; Mice, Inbred C57BL; Mice, SCID; Severe Combined Immunodeficiency; Swine; Time Factors

2011
Total desmosines in plasma and urine correlate with lung function.
    The European respiratory journal, 2012, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Biomarkers; Desmosine; Female; Humans; Isodesmosine; Lung; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Registries; Respiratory Function Tests; Sensitivity and Specificity; Smoking

2012
Lysyl oxidase regulates MMTV promoter: indirect evidence of histone H1 involvement.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2011, Volume: 89, Issue:6

    Topics: Aminopropionitrile; Cell Line, Tumor; Desmosine; Dexamethasone; Genetic Vectors; Histones; Humans; Immunoprecipitation; Isodesmosine; Luciferases; Mammary Tumor Virus, Mouse; Phosphorylation; Promoter Regions, Genetic; Protein-Lysine 6-Oxidase; Recombinant Proteins; Transcription Factors; Transcriptional Activation; Transfection

2011
Determination of free desmosine and isodesmosine as urinary biomarkers of lung disorder using ultra performance liquid chromatography-ion mobility-mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Dec-15, Volume: 879, Issue:32

    Topics: Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Desmosine; Female; Humans; Isodesmosine; Limit of Detection; Linear Models; Male; Mass Spectrometry; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results

2011
Desmosine, a biomarker for COPD: old and in the way.
    The European respiratory journal, 2012, Volume: 39, Issue:4

    Topics: Desmosine; Female; Humans; Isodesmosine; Lung; Male; Pulmonary Disease, Chronic Obstructive

2012
Secondhand smoke exposure effect on elastin degradation markers: which factors should be taken into account?
    Chest, 2012, Volume: 141, Issue:4

    Topics: Desmosine; Elastin; Female; Humans; Isodesmosine; Male; Tobacco Smoke Pollution

2012
Repeatability of and relationship between potential COPD biomarkers in bronchoalveolar lavage, bronchial biopsies, serum, and induced sputum.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Adult; Aged; Analysis of Variance; Biomarkers; Biopsy; Bronchoalveolar Lavage Fluid; Bronchoscopy; C-Reactive Protein; Cytokines; Desmosine; Female; Humans; Interleukin-6; Isodesmosine; Lung; Male; Middle Aged; Neutrophils; Pulmonary Disease, Chronic Obstructive; Smoking; Sputum; Time Factors; von Willebrand Factor

2012
Electron transfer and collision induced dissociation of non-derivatized and derivatized desmosine and isodesmosine.
    Journal of the American Society for Mass Spectrometry, 2013, Volume: 24, Issue:1

    Topics: Anhydrides; Chromatography, Liquid; Desmosine; Isodesmosine; Isomerism; Mass Spectrometry; Polyethylene Glycols; Propionates

2013
Stable deuterium internal standard for the isotope-dilution LC-MS/MS analysis of elastin degradation.
    Analytical biochemistry, 2013, Sep-15, Volume: 440, Issue:2

    Topics: Biomarkers; Bronchoalveolar Lavage; Chromatography, Liquid; Desmosine; Deuterium; Elastin; Humans; Isodesmosine; Proteolysis; Pulmonary Disease, Chronic Obstructive; Reference Standards; Tandem Mass Spectrometry

2013
Characterization and validation of an isotope-dilution LC-MS/MS method for quantification of total desmosine and isodesmosine in plasma and serum.
    Bioanalysis, 2013, Volume: 5, Issue:16

    Topics: Chromatography, Liquid; Desmosine; Humans; Indicator Dilution Techniques; Isodesmosine; Tandem Mass Spectrometry

2013
Disruption of elastic lamellae in the aorta by D-penicillamine and its effect on vaso-regulation in rats.
    The Journal of toxicological sciences, 2013, Volume: 38, Issue:5

    Topics: Administration, Oral; Age Factors; Amino Acids; Animals; Aorta; Arterial Pressure; Cardiovascular Diseases; Chelating Agents; Desmosine; Elastic Tissue; Elasticity; Elastin; Humans; Injections, Subcutaneous; Isodesmosine; Male; Penicillamine; Rats; Rats, Sprague-Dawley

2013
Disruption of elastic lamellae in aorta and dysfunction of vaso-regulation by rofecoxib in rats.
    The Journal of toxicological sciences, 2013, Volume: 38, Issue:5

    Topics: Administration, Oral; Age Factors; Amino Acids; Animals; Aorta; Arterial Pressure; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Desmosine; Elastic Tissue; Elasticity; Elastin; Humans; Injections, Subcutaneous; Isodesmosine; Lactones; Male; Rats; Rats, Sprague-Dawley; Sulfones

2013
Quantification of free and total desmosine and isodesmosine in human urine by liquid chromatography tandem mass spectrometry: a comparison of the surrogate-analyte and the surrogate-matrix approach for quantitation.
    Journal of chromatography. A, 2014, Jan-24, Volume: 1326

    Topics: Aged; Biomarkers; Calibration; Case-Control Studies; Chromatography, Liquid; Desmosine; Female; Humans; Isodesmosine; Male; Middle Aged; Peptides; Pulmonary Disease, Chronic Obstructive; Tandem Mass Spectrometry

2014
Biomimetic Chichibabin pyridine synthesis of the COPD biomarkers and elastin cross-linkers isodesmosine and desmosine.
    Organic letters, 2014, Mar-21, Volume: 16, Issue:6

    Topics: Biomarkers; Biomimetics; Cross-Linking Reagents; Desmosine; Elastin; Humans; Isodesmosine; Lanthanoid Series Elements; Molecular Structure; Pulmonary Disease, Chronic Obstructive; Pyridines; Pyridinium Compounds

2014
Fingerprinting desmosine-containing elastin peptides.
    Journal of the American Society for Mass Spectrometry, 2015, Volume: 26, Issue:5

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Desmosine; Elastin; Humans; Isodesmosine; Models, Molecular; Molecular Structure; Molecular Weight; Oligopeptides; Peptide Fragments; Peptide Mapping; Protein Stability; Proteolysis; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry; Tropoelastin

2015
The Ratio of Free to Bound Desmosine and Isodesmosine May Reflect Emphysematous Changes in COPD.
    Lung, 2015, Volume: 193, Issue:3

    Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Chromatography, Liquid; Desmosine; Disease Models, Animal; Female; Isodesmosine; Lung; Mesocricetus; Pancreatic Elastase; Predictive Value of Tests; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Severity of Illness Index; Tandem Mass Spectrometry

2015
Elastin degradation product isodesmosine is a chemoattractant for Pseudomonas aeruginosa.
    Microbiology (Reading, England), 2015, Volume: 161, Issue:7

    Topics: Bacterial Proteins; Chemotactic Factors; Chemotaxis; Desmosine; Elastin; Humans; Isodesmosine; Pseudomonas aeruginosa; Pseudomonas Infections

2015
[(13)C3,(15)N1]-labeled isodesmosine: A potential internal standard for LC-MS/MS analysis of desmosines in elastin degradation.
    Bioorganic & medicinal chemistry letters, 2015, Volume: 25, Issue:10

    Topics: Biomarkers; Carbon Isotopes; Chromatography, Liquid; Desmosine; Elastin; Isodesmosine; Molecular Structure; Nitrogen Isotopes; Pulmonary Disease, Chronic Obstructive; Tandem Mass Spectrometry

2015
Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease.
    The European respiratory journal, 2016, Volume: 48, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Desmosine; Elastin; Female; Forced Expiratory Volume; Humans; Isodesmosine; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Smoking; Time Factors

2016
The Pattern of Elastic Fiber Breakdown in Bleomycin-Induced Pulmonary Fibrosis May Reflect Microarchitectural Changes.
    Lung, 2017, Volume: 195, Issue:1

    Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cricetinae; Desmosine; Elastic Tissue; Emphysema; Female; Isodesmosine; Lung; Lymphocyte Count; Neutrophils; Pancreatic Elastase; Proteins; Pulmonary Fibrosis

2017
Urinary desmosine is associated with emphysema severity and frequent exacerbation in patients with COPD.
    Respirology (Carlton, Vic.), 2018, Volume: 23, Issue:2

    Topics: Aged; Biomarkers; Cohort Studies; Desmosine; Female; Humans; Isodesmosine; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Severity of Illness Index; Tomography, X-Ray Computed

2018
Vitamin K deficit and elastolysis theory in pulmonary elasto-degenerative diseases.
    Medical hypotheses, 2017, Volume: 108

    Topics: alpha 1-Antitrypsin; Biomarkers; Calcium; Calcium-Binding Proteins; Desmosine; Elasticity; Elastin; Extracellular Matrix Proteins; Humans; Isodesmosine; Lung Diseases; Matrix Gla Protein; Models, Biological; Vitamin K; Vitamin K Deficiency

2017
The Therapeutic Potential of Hyaluronan in COPD.
    Chest, 2018, Volume: 153, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Biomarkers; Clinical Trials as Topic; Desmosine; Disease Models, Animal; Elastin; Glycosaminoglycans; Humans; Hyaluronic Acid; Immunity, Cellular; Isodesmosine; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats

2018
Chronic Obstructive Pulmonary Disease. A Biomarker and a Potential Therapy.
    Annals of the American Thoracic Society, 2018, Volume: 15, Issue:Suppl 1

    Topics: alpha 1-Antitrypsin Deficiency; Animals; Biomarkers; Desmosine; Elastin; Humans; Isodesmosine; Leukocyte Elastase; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema

2018
Free lung desmosine: a potential biomarker for elastic fiber injury in pulmonary emphysema.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2022, Volume: 27, Issue:4

    Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Chromatography, Liquid; Cricetinae; Desmosine; Elastic Tissue; Formaldehyde; Humans; Isodesmosine; Lipopolysaccharides; Lung; Pulmonary Emphysema; Tandem Mass Spectrometry

2022
LC-MS/MS quantitation of elastin crosslinker desmosines and histological analysis of skin aging characteristics in mice.
    Bioorganic & medicinal chemistry, 2023, 07-15, Volume: 90

    Topics: Animals; Chromatography, Liquid; Desmosine; Elastin; Humans; Isodesmosine; Mice; Skin Aging; Tandem Mass Spectrometry

2023