Page last updated: 2024-08-24

isocytosine and cytosine

isocytosine has been researched along with cytosine in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.63)18.7374
1990's6 (13.95)18.2507
2000's12 (27.91)29.6817
2010's15 (34.88)24.3611
2020's5 (11.63)2.80

Authors

AuthorsStudies
Hobza, P; Sponer, J1
Levy, M; Miller, SL; Robertson, MP1
Demidov, VV; Frank-Kamenetskii, MD; Kuhn, H; Nielsen, PE1
Chaput, JC; Roberts, C; Switzer, C1
Leonard, P; Melenewski, A; Seela, F; Wei, C1
Ikeda, S; Saito, I; Sugiyama, H; Wang, AH; Yang, XL1
Chang, FC; Chang, ML; Cheng, AY; Chin, TM; Huang, DH; Kan, LS; Lee, SY; Lin, SB; Pasternack, L1
Chaput, JC; Switzer, C1
Chacklos, J; Clarke, MJ; Galang, RD; Gallagher, ML; Jian, W; LaChance-Galang, KJ; Maldonado, I; Prock, A1
Gunthard, HH; Ha, TK1
VAN ARMAN, CG1
DOUZOU, P; HELENE, C2
DEWAR, JH; SHAW, G1
Johnson, SC; Marshall, DJ; Moser, MJ; Prudent, JR; Sherrill, CB1
Gupta, D; Huelsekopf, M; Lippert, B; Ludwig, R; Morell Cerdà, M1
Arndt-Jovin, DJ; Geinguenaud, F; Jovin, TM; Klement, R; Liquier, J; Mondragon-Sanchez, JA; Shchyolkina, AK; Taillandier, E1
Gupta, D; Lippert, B; Roitzsch, M1
Benner, SA; Sismour, AM1
Delchev, VB; Mikosch, H1
Albert, JS; de Beer, T; Deinum, J; Edwards, PD; Folmer, RH; Geschwindner, S; Olsson, LL1
Aharony, D; Albert, JS; Andisik, D; Callaghan, O; Campbell, JB; Carr, RA; Chessari, G; Congreve, M; Edwards, PD; Folmer, RH; Frederickson, M; Geschwindner, S; Koether, G; Kolmodin, K; Krumrine, J; Mauger, RC; Murray, CW; Olsson, LL; Patel, S; Spear, N; Sylvester, M; Tian, G1
Hong, JH; Liu, LJ1
REUTER, MA; STIMSON, MM1
Barrett, S; Fisher, J; Gooch, A; Lindsay, CI; Wilson, AJ1
B-Rao, C; Bahirat, U; Brahma, MK; Deshmukh, NJ; Dixit, A; Doshi, L; Ghosh, U; Katkar, KV; Keche, A; Khanna, S; Korde, V; Kulkarni-Almeida, A; Nemmani, KV; Shah, P; Sharma, R; Sivaramakrishnan, H; Srivastava, A1
Bakalska, RI; Delchev, VB1
B-Rao, C; Bahirat, U; Bajaj, K; Brahma, MK; Burudkar, S; Damre, A; Desai, A; Deshmukh, NJ; Dixit, A; Doshi, L; Ghosh, U; Keche, A; Khanna, S; Kulkarni-Almeida, A; Nemmani, KV; Shah, P; Sharma, R; Sivaramakrishnan, H; Srivastava, A; Tannu, P1
Ahire, Y; B-Rao, C; Bajaj, K; Burudkar, S; Damre, A; Deshmukh, NJ; Dixit, A; Ghosh, U; Keche, A; Khanna, S; Kulkarni-Almeida, A; Nemmani, KV; Shah, P; Sharma, R; Sivaramakrishnan, H; Srivastava, A; Tannu, P1
Arisawa, M; Hattori, K; Hosono, M; Muto, C; Nakano, T; Sakagami, M; Shuto, S; Takemoto, H; Tanaka, Y; Togame, H; Yamakawa, H; Yamamoto, T; Yonezawa, S1
Bilbao, N; Camacho-García, J; González-Rodríguez, D; López-Pérez, AM; Montoro-García, C; Romero-Pérez, S1
Rzymowska, J; Sztanke, K; Sztanke, M1
Leszczynska, G; Nawrot, B; Sadowska, K; Sierant, M; Sobczak, M; Sochacka, E1
Abbot, V; Gupta, MK; Narang, BK; Rawal, RK; Roy, S; Singh, V1
Boguszewska, A; Polz-Dacewicz, M; Rajtar, B; Świątek, Ł; Sztanke, K; Sztanke, M1
Darinskas, A; Kazlauskas, A; Meškys, R; Tamašauskas, A; Urbonavičius, J1
Bethel, PA; Gill, DM; Ochocińska, AM; Sweeney, JB; Walsh, AEJ; Walton, SM1
Cavallo, L; Chawla, M; Minenkov, Y; Oliva, R; Vu, KB1
Dračínský, M; Štoček, JR1
Bearpark, MJ; Segarra-Martí, J2
Fordham, JM; Piacentini, P; Santagostino, M1
Ding, Z; Liu, L; Peng, Z; Qi, B; Wu, Y1

Other Studies

43 other study(ies) available for isocytosine and cytosine

ArticleYear
G.C base pair in parallel-stranded DNA--a novel type of base pairing: an ab initio quantum chemical study.
    Journal of biomolecular structure & dynamics, 1994, Volume: 12, Issue:3

    Topics: Base Composition; Computer Simulation; Cytosine; DNA; Guanosine; Hydrogen Bonding; Models, Chemical; Nucleic Acid Conformation; Quantum Theory; Thermodynamics

1994
Prebiotic synthesis of diaminopyrimidine and thiocytosine.
    Journal of molecular evolution, 1996, Volume: 43, Issue:6

    Topics: Acetaldehyde; Cytosine; Evolution, Molecular; Guanidine; Hydrogen-Ion Concentration; Hydrolysis; Pyrimidines; Seawater; Solubility; Temperature; Thiourea; Uracil

1996
Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA.
    Nucleic acids research, 1998, Jan-15, Volume: 26, Issue:2

    Topics: Animals; Base Sequence; Cations; Cytosine; DNA; DNA, Complementary; Electrochemistry; Kinetics; Male; Nucleic Acids; Osmolar Concentration; Peptides; Salmon; Sodium; Structure-Activity Relationship

1998
Beyond guanine quartets: cation-induced formation of homogenous and chimeric DNA tetraplexes incorporating iso-guanine and guanine.
    Chemistry & biology, 1997, Volume: 4, Issue:12

    Topics: Cations; Cross-Linking Reagents; Cytosine; DNA; Electrophoresis, Polyacrylamide Gel; Genome; Guanine; Mutagenesis; Oligonucleotides; Photochemistry; Spectrophotometry, Ultraviolet

1997
Parallel-stranded duplexes and quartet assemblies formed by oligonucleotides containing isoguanine.
    Nucleic acids symposium series, 1997, Issue:37

    Topics: Base Composition; Cytosine; Drug Stability; Guanine; Hydrogen Bonding; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Pyrimidines; Pyrroles

1997
Structural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopy.
    Biophysical journal, 1998, Volume: 75, Issue:3

    Topics: Base Pairing; Base Sequence; Biophysical Phenomena; Biophysics; Cytosine; DNA; Drug Stability; Guanine; Intercalating Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides

1998
"Paper-clip" type triple helix formation by 5'-d-(TC)3Ta(CT)3Cb(AG)3 (a and b = 0-4) as a function of loop size with and without the pseudoisocytosine base in the Hoogsteen strand.
    Biochemistry, 2000, Oct-10, Volume: 39, Issue:40

    Topics: Adenine; Base Composition; Base Pairing; Base Sequence; Cytidine; Cytosine; DNA; Guanine; Magnesium Chloride; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Protons; Thermodynamics; Thionucleotides; Thymine

2000
Probing structure and function with alternative nucleic acids bearing 2',5'-linked, zwitterionic, and isocytosine-isoguanine components.
    Methods (San Diego, Calif.), 2001, Volume: 23, Issue:2

    Topics: Carbohydrates; Cytosine; DNA; Escherichia coli; Genetic Techniques; Guanine; Models, Chemical; Nucleic Acids; Rec A Recombinases

2001
Terpsichorean movements of pentaammineruthenium on pyrimidine and isocytosine ligands.
    Inorganic chemistry, 2001, Jan-29, Volume: 40, Issue:3

    Topics: Catalysis; Cytosine; Electrochemistry; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Pyrimidines; Ruthenium Compounds; Thermodynamics

2001
Quantum chemistry predicted correlations between geometric isomerism (conformation) of -OH and =NH substituents and typical group frequencies of nucleic acid bases: cytosine.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2001, Volume: 57, Issue:1

    Topics: Adenine; Calorimetry; Cytosine; Guanine; Isomerism; Models, Molecular; Molecular Conformation; Quantum Theory; Uracil; Xanthine

2001
The diuretic activity of isocytosines.
    The Journal of pharmacology and experimental therapeutics, 1954, Volume: 111, Issue:3

    Topics: Cytosine; Diuresis; Diuretics; Pyrimidines

1954
[TAUTOMERIC FORMS OF ISOCYTOSINE, OF CYTOSINE AND CYTIDINE. A STUDY OF THE FUNCTION OF TEMPERATURE].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Dec-21, Volume: 259

    Topics: Chemical Phenomena; Chemistry; Cytidine; Cytosine; Kinetics; Nucleosides; Research; Spectrophotometry; Temperature

1964
[TAUTOMERIC FORMS OF ISOCYTOSINE. STUDY BY ABSORPTION SPECTROPHOTOMETRY].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Dec-09, Volume: 259

    Topics: Chemical Phenomena; Chemistry; Cytosine; Hydrogen-Ion Concentration; Nucleosides; Research; Spectrophotometry

1964
PURINES, PYRIMIDINES, AND IMIDAZOLES. XXI. SOME URACILS AND ISOCYTOSINES.
    Journal of the Chemical Society, 1965, Volume: 65

    Topics: Cytosine; Imidazoles; Purines; Pyrimidines; Research; Spectrum Analysis; Uracil

1965
A third base pair for the polymerase chain reaction: inserting isoC and isoG.
    Nucleic acids research, 2004, Volume: 32, Issue:6

    Topics: Adenosine; Base Pairing; Cytosine; DNA; DNA Primers; DNA-Directed DNA Polymerase; Guanosine; Molecular Probes; Nucleic Acid Denaturation; Polymerase Chain Reaction

2004
Complex formation of isocytosine tautomers with PdII and PtII.
    Inorganic chemistry, 2004, May-31, Volume: 43, Issue:11

    Topics: Alkadienes; Binding Sites; Crystallography, X-Ray; Cytosine; Hydrogen Bonding; Isomerism; Ketones; Ligands; Molecular Structure; Organometallic Compounds; Organoplatinum Compounds; Palladium; Platinum; Protons; Thermodynamics

2004
Parallel DNA double helices incorporating isoG or m5isoC bases studied by FTIR, CD and molecular modeling.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:4

    Topics: Base Composition; Base Pairing; Carbohydrates; Circular Dichroism; Cytosine; Deoxyribose; DNA; Guanine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Nucleic Acid Denaturation; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Thymine

2005
Isocytosine as a hydrogen-bonding partner and as a ligand in metal complexes.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2005, Nov-04, Volume: 11, Issue:22

    Topics: Crystallography, X-Ray; Cytosine; Hydrogen Bonding; Ligands; Metals, Heavy; Models, Molecular; Molecular Structure; Organometallic Compounds; Palladium; Platinum; Stereoisomerism

2005
The use of thymidine analogs to improve the replication of an extra DNA base pair: a synthetic biological system.
    Nucleic acids research, 2005, Volume: 33, Issue:17

    Topics: Base Pairing; Cytosine; DNA Polymerase I; DNA Primers; DNA Replication; Guanine; Oligonucleotides; Polymerase Chain Reaction; Thymidine; Thymine Nucleotides

2005
Theoretical study of the intermolecular H-bonding and intermolecular proton transfer between isocytosine tautomeric forms and R,S-lactic acid.
    Journal of molecular modeling, 2007, Volume: 13, Issue:1

    Topics: Carboxylic Acids; Cytosine; Hydrogen Bonding; Lactic Acid; Models, Chemical; Models, Theoretical; Molecular Conformation; Normal Distribution; Protons; Software; Stereoisomerism; Thermodynamics

2007
Discovery of a novel warhead against beta-secretase through fragment-based lead generation.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line; Crystallography, X-Ray; Cytosine; Drug Design; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Recombinant Fusion Proteins; Structure-Activity Relationship

2007
Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Amidines; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line; Crystallography, X-Ray; Cytosine; Fluorescence Resonance Energy Transfer; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Pyrimidines; Stereoisomerism; Structure-Activity Relationship

2007
Design and synthesis of novel SATE derivatives of acyclic isocytosine and 9-deazaadenine C-nucleosides.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:3

    Topics: Anti-HIV Agents; Cytosine; Drug Design; HIV-1; Microbial Sensitivity Tests; Molecular Structure; Prodrugs; Stereoisomerism; Structure-Activity Relationship; Tubercidin; Zidovudine

2010
The ultraviolet absorption spectra of cytosine and isocytosine.
    Journal of the American Chemical Society, 1945, Volume: 67

    Topics: Cytosine

1945
Ditopic triply hydrogen-bonded heterodimers.
    Organic & biomolecular chemistry, 2011, Sep-07, Volume: 9, Issue:17

    Topics: Cytosine; Dimerization; Hydrogen Bonding; Imidazoles; Magnetic Resonance Spectroscopy

2011
Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits.
    Bioorganic & medicinal chemistry, 2012, May-01, Volume: 20, Issue:9

    Topics: Animals; Computer Simulation; Cytosine; Enzyme Activation; Enzyme Inhibitors; Hyperuricemia; Male; Oxonic Acid; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthine Oxidase

2012
Comparative study of the relaxation mechanisms of the excited states of cytosine and isocytosine.
    Journal of molecular modeling, 2012, Volume: 18, Issue:12

    Topics: Cytosine; Isomerism; Kinetics; Models, Molecular; Molecular Conformation; Photochemical Processes; Quantum Theory; Spectrophotometry, Ultraviolet; Thermodynamics; Ultraviolet Rays

2012
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Administration, Oral; Animals; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Hyperuricemia; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Rats, Wistar; Structure-Activity Relationship; Time Factors; Xanthine Oxidase

2012
Lead optimization of isocytosine-derived xanthine oxidase inhibitors.
    Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3

    Topics: Administration, Oral; Animals; Catalytic Domain; Cytosine; Enzyme Activation; Enzyme Inhibitors; Inhibitory Concentration 50; Models, Animal; Models, Molecular; Molecular Structure; Rats; Xanthine Oxidase

2013
Conformational restriction approach to BACE1 inhibitors II: SAR study of the isocytosine derivatives fixed with a cis-cyclopropane ring.
    Bioorganic & medicinal chemistry letters, 2013, May-15, Volume: 23, Issue:10

    Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Crystallography, X-Ray; Cyclopropanes; Cytosine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Conformation; Structure-Activity Relationship

2013
Synthesis and complementary self-association of novel lipophilic π-conjugated nucleoside oligomers.
    Organic & biomolecular chemistry, 2015, Apr-21, Volume: 13, Issue:15

    Topics: Adenosine; Cytosine; Dimerization; Guanosine; Hydrogen Bonding; Nucleosides; Polymers; Uridine

2015
In vitro effects of a new fused azaisocytosine-like congener on relative cell proliferation, necrosis and cell cycle in cancer and normal cell cultures.
    Molecular and cellular biochemistry, 2016, Volume: 418, Issue:1-2

    Topics: Cell Division; Cytosine; G2 Phase; HeLa Cells; Humans; Multiple Myeloma

2016
Reaction of S-geranyl-2-thiouracil modified oligonucleotides with alkyl amines leads to the N2-alkyl isocytosine derivatives.
    Organic & biomolecular chemistry, 2017, Jun-27, Volume: 15, Issue:25

    Topics: Amines; Cytosine; Molecular Structure; Oligonucleotides; Terpenes; Thiouracil

2017
Molecular Docking Studies on Isocytosine Analogues as Xanthine Oxidase Inhibitors.
    Drug research, 2018, Volume: 68, Issue:7

    Topics: Catalytic Domain; Cytosine; Enzyme Inhibitors; Molecular Docking Simulation; Structure-Activity Relationship; Xanthine Oxidase

2018
The influence of some promising fused azaisocytosine-containing congeners on zebrafish (Danio rerio) embryos/larvae and their antihaemolytic, antitumour and antiviral activities.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Apr-30, Volume: 132

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Aza Compounds; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Cytosine; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Erythrocytes; Hemolysis; Herpesvirus 1, Human; Heterocyclic Compounds, Fused-Ring; Vero Cells; Virus Replication; Zebrafish

2019
Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cytosine; Cytosine Deaminase; Flucytosine; Fluorouracil; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Glioblastoma; Humans; Lentivirus; Mesenchymal Stem Cells; Mice; Nucleoside Deaminases; Prodrugs

2019
Synthesis of a Protected keto-Lysidine Analogue via Improved Preparation of Arabino-isoCytosine Nucleosides.
    Organic letters, 2019, 04-05, Volume: 21, Issue:7

    Topics: Amines; Cytosine; Lysine; Molecular Structure; Nucleosides; Pyrimidine Nucleosides; RNA, Transfer

2019
Structural and Energetic Impact of Non-natural 7-Deaza-8-azaguanine, 7-Deaza-8-azaisoguanine, and Their 7-Substituted Derivatives on Hydrogen-Bond Pairing with Cytosine and Isocytosine.
    Chembiochem : a European journal of chemical biology, 2019, 09-02, Volume: 20, Issue:17

    Topics: Azaguanine; Base Pairing; Cytosine; Hydrogen Bonding; Molecular Structure; Thermodynamics

2019
Tautomerism of Guanine Analogues.
    Biomolecules, 2020, 01-22, Volume: 10, Issue:2

    Topics: Cytosine; Dimerization; DNA; Electrons; Guanine; Hydrogen; Hydrogen Bonding; Macromolecular Substances; Magnetic Resonance Spectroscopy; Normal Distribution; Quantum Theory; Reproducibility of Results; Stereoisomerism; Thermodynamics

2020
Modelling Photoionisation in Isocytosine: Potential Formation of Longer-Lived Excited State Cations in its Keto Form.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2021, 11-04, Volume: 22, Issue:21

    Topics: Cations; Cytosine; Ketones; Models, Molecular; Molecular Structure; Photochemical Processes; Ultraviolet Rays

2021
Modelling Photoionisation in Isocytosine: Potential Formation of Longer-Lived Excited State Cations in its Keto Form.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2021, 11-04, Volume: 22, Issue:21

    Topics: Cations; Cytosine; DNA; Ketones; Models, Molecular; Molecular Structure; Photochemical Processes; Ultraviolet Rays

2021
Pd-Catalyzed Ring-Opening/Arylation/Cyclization of 2-Aminothiazole Derivatives Provides Modular Access to Isocytosine Analogues.
    The Journal of organic chemistry, 2022, 10-07, Volume: 87, Issue:19

    Topics: Cyclization; Cytosine; Kinetics; Palladium; Thiazoles

2022
Construction of Isocytosine Scaffolds via DNA-Compatible Biginelli-like Reaction.
    Organic letters, 2023, 07-28, Volume: 25, Issue:29

    Topics: Aldehydes; Cytosine; DNA; Guanidine

2023