isocryptolepine and ammonium-peroxydisulfate

isocryptolepine has been researched along with ammonium-peroxydisulfate* in 1 studies

Other Studies

1 other study(ies) available for isocryptolepine and ammonium-peroxydisulfate

Article	Year
Radical Beckmann Rearrangement and Its Application in the Formal Total Synthesis of Antimalarial Natural Product Isocryptolepine via C-H Activation. Organic letters, 2016, 07-15, Volume: 18, Issue:14 The Beckmann rearrangement of ketoximes, mediated by ammonium persulfate-dimethyl sulfoxide as a reagent, has been achieved under neutral conditions. Based on the radical trapping and (18)O-labeling experiments, the transformation follows a mechanism involving a radical pathway. The scope and generality of the developed protocol has been demonstrated by 19 examples. The developed protocol and Pd-catalyzed intramolecular double C-H activation were used as key steps in the formal total synthesis of antimalarial natural product isocryptolepine. Topics: Ammonium Sulfate; Antimalarials; Catalysis; Dimethyl Sulfoxide; Free Radical Scavengers; Free Radicals; Indole Alkaloids; Quinolines; Stereoisomerism	2016

Article

Year

Radical Beckmann Rearrangement and Its Application in the Formal Total Synthesis of Antimalarial Natural Product Isocryptolepine via C-H Activation.

Organic letters, 2016, 07-15, Volume: 18, Issue:14

The Beckmann rearrangement of ketoximes, mediated by ammonium persulfate-dimethyl sulfoxide as a reagent, has been achieved under neutral conditions. Based on the radical trapping and (18)O-labeling experiments, the transformation follows a mechanism involving a radical pathway. The scope and generality of the developed protocol has been demonstrated by 19 examples. The developed protocol and Pd-catalyzed intramolecular double C-H activation were used as key steps in the formal total synthesis of antimalarial natural product isocryptolepine.

Topics: Ammonium Sulfate; Antimalarials; Catalysis; Dimethyl Sulfoxide; Free Radical Scavengers; Free Radicals; Indole Alkaloids; Quinolines; Stereoisomerism

2016