isocoumarins has been researched along with warfarin in 177 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (9.04) | 18.7374 |
| 1990's | 91 (51.41) | 18.2507 |
| 2000's | 45 (25.42) | 29.6817 |
| 2010's | 23 (12.99) | 24.3611 |
| 2020's | 2 (1.13) | 2.80 |
| Authors | Studies |
|---|---|
| Akada, Y; Gotoh, M; Kawano, S; Tanase, Y | 1 |
| Anke, H; Zähner, H | 1 |
| Hecker, M; Kaw, S; Southan, GJ; Vane, JR; Warner, TD | 1 |
| Baumeister, W; Dahlmann, B; Grziwa, A; Kuehn, L; Zwickl, P | 1 |
| Djaballah, H; Harness, JA; Rivett, AJ; Savory, PJ | 1 |
| Hanada, K; Ito, M; Maruhashi, M; Mizoue, K; Sakai, N | 1 |
| Chatani, N; Murakami, N; Uchida, E; Yamahara, J; Yoshikawa, M | 1 |
| Cardozo, C; Hidalgo, MC; Michaud, C; Orlowski, M; Vinitsky, A | 1 |
| Glinski, J; Hernandez, MA; Meyer, EF; Oleksyszyn, J; Powers, JC; Vijayalakshmi, J | 1 |
| Margolis, JW; Nguyen, T; Pereira, ME; Wagner, BJ; Wilk, S; Yu, B | 1 |
| Djaballah, H; Rivett, AJ | 1 |
| Aebersold, R; Greenberg, AH; Kraut, RP; Shi, L | 1 |
| Hausen, BM | 1 |
| Itoh, M; Kurosaki, F; Nishi, A; Yamada, M | 1 |
| Kam, CM; Meyer, EF; Powers, JC; Vijayalakshmi, J | 1 |
| Hamada, M; Hattori, S; Ishizuka, M; Kumagai, H; Masuda, T; Naganawa, H; Ohsono, M; Sawa, T; Takeuchi, T | 1 |
| Mason, RW | 1 |
| Kam, CM; Narasimhan, SL; Oleksyszyn, J; Powers, JC | 1 |
| Kam, CM; Ku, DN; Lumsden, AB; Oweida, SW; Powers, JC | 1 |
| Beynon, RJ; Rusbridge, NM | 1 |
| Kakegawa, H; Matsumoto, H; Satoh, T | 1 |
| Michaud, C; Orlowski, M | 1 |
| Li, X; Pei, YH; Zhu, TR | 1 |
| Carrasco, L | 1 |
| Bruynzeel, DP; Hausen, BM | 1 |
| Kasuya, Y; Urushidani, T; Yano, S | 1 |
| Harper, JW; Hemmi, K; Powers, JC | 1 |
| Baba, T; Hayashi, H; Shimojima, Y; Shirai, T | 1 |
| Hagiwara, Y; Hashimoto, Y; Konishi, T; Kurokawa, N; Tachibana, Y | 1 |
| Chaudhuri, RK; Ghosal, S; Sharma, PV; Singh, AK | 1 |
| Hayashi, H; Shimojima, Y | 1 |
| Kawai, K; Nakajima, S; Nozawa, K; Tsuda, Y; Yamada, M | 1 |
| Kim, SH; Kim, SJ; Shin, JM; Shin, W | 1 |
| Enghild, JJ; Pizzo, SV; Thøgersen, IB; Valnickova, Z | 1 |
| Harada, E; Inoue, K; Matsuda, H; Murakami, N; Naitoh, Y; Shimoda, H; Yamahara, J; Yoshikawa, M | 1 |
| Clemmons, DR; Gockerman, A | 1 |
| Chow, SC; Eriksson, JE; Holmström, TH; Kass, GE; Orrenius, S; Weis, M | 1 |
| Anees, M; Steven, FS | 1 |
| Matsuda, H; Murakami, N; Shimoda, H; Wariishi, N; Yagi, N; Yamahara, J; Yoshikawa, M | 1 |
| Ishizuka, M; Kawatsu, M; Takeuchi, T; Ueno, M; Yamashita, T | 1 |
| Cardozo, C; Eleuteri, AM; Orlowski, M | 1 |
| Ishizuka, M; Kumagai, H; Masuda, T; Takeuchi, T | 1 |
| Guesdon, F; Haskill, S; Ikebe, T; Saklatvala, J; Stylianou, E; Warwick-Davies, J | 1 |
| Baumeister, W; Huber, R; Löwe, J; Lupas, A; Seemüller, E; Stock, D | 1 |
| Atkinson, EA; Bleackley, RC; Helgason, CD; Pinkoski, MJ | 1 |
| Iijima, M; Ishizuka, M; Kumagai, H; Osono, M; Sakashita, M; Takeuchi, T | 1 |
| Ishizuka, M; Kumagai, H; Masuda, T; Sakashita, M; Takeuchi, T | 1 |
| Agata, N; Hirano, S; Iguchi, H; Ishizuka, M; Mase, T; Matsufuji, M; Sakata, N; Tone, H; Wakazono, K; Yamamoto, R | 1 |
| Christensen, S; Enghild, JJ; Nielsen, HR; Pizzo, SV; Roepstorff, P; Thøgersen, IB; Valnickova, Z | 1 |
| Parent, D; Remold-O'Donnell, E | 1 |
| Dietrich, J; Kovács, T; Sonnenbichler, J; Zetl, I | 1 |
| Liu, HY; Yang, DJ; Zhong, ZC | 1 |
| Bast, RC; Becherer, JD; Boyer, CM; Champion, B; Connolly, KM; Conway, JG; Furdon, P; Karp, S; Kidao, S; McGeehan, GM | 1 |
| Bochan, MR; Brahmi, Z; Froelich, CJ; Hanna, WL; Su, B | 1 |
| Duffy, EJ; Kam, CM; Kerrigan, JE; Lollar, P; Plaskon, RR; Powers, JC; Suddath, FL | 1 |
| Chatani, N; Harada, E; Murakami, N; Nishino, Y; Yamahara, J; Yoshikawa, M | 1 |
| Amemiya, M; Ishizuka, M; Kumagai, H; Naganawa, H; Sawa, T; Takeuchi, T | 1 |
| Cutler, HG; Harwood, JS; Jacyno, JM; Lee, MK | 1 |
| Kurosaki, F; Nishi, A | 1 |
| Strobl, B; Vlasak, R | 1 |
| Cardozo, C; Michaud, C; Orlowski, M | 2 |
| Megyeri, P; Pabst, KM; Pabst, MJ | 1 |
| Busse, R; Hecker, M; Preiss, C; Schini-Kerth, VB | 1 |
| Fagan, JM; Strack, PR; Waxman, L | 1 |
| Schnellmann, RG; Yang, X | 1 |
| Kerrigan, JE; Powers, JC; VanDerveer, D | 1 |
| Ito, K; Kabashima, T; Kitano, A; Kitazono, A; Yoshimoto, T | 1 |
| Abe, C; Agata, N; Hirano, S; Iguchi, H; Ishizuka, M; Mase, T; Matsufuji, M; Sakata, N; Wakazono, K; Yamamoto, R | 1 |
| Lu, Q; Mellgren, RL | 1 |
| Colas, B; Durand, P; Roy, P | 1 |
| Matsuda, H; Murakami, N; Shimada, H; Shimoda, H; Yagi, N; Yamahara, J; Yoshikawa, M | 1 |
| Brodsky, JL; McCracken, AA; Werner, ED | 1 |
| Björk, I; Olson, ST; Patston, PA; Swanson, R | 1 |
| Bettaïeb, A; Jaffrézou, JP; Laurent, G; Levade, T; Mansat, V | 1 |
| Bisogni, R; Bonelli, P; Cerra, M; Ferrone, S; Lamberti, A; Petrella, A; Romano, MF; Sun, SC; Turco, MC; Venuta, S | 1 |
| Araújo, MC; Dias, Fde L; Gibran, SC; Raddi, MS; Takahashi, CS; Varanda, EA; Vilegas, W | 1 |
| Pommier, Y; Shimizu, T | 1 |
| Bochan, MR; Brahmi, Z; Froelich, CJ; Goebel, WS; Hommel-Berrey, GA; Montel, AH | 1 |
| Cardozo, C; Eleuteri, AM; Kam, CM; Kohanski, R; Orlowski, M; Powers, JC | 1 |
| Cao, CX; Pommier, Y; Shao, RG; Shimizu, T | 1 |
| Hintze, TH; Nasjletti, A; Xu, X; Zhang, X | 1 |
| Kawai, K; Mori, H; Okamoto, K; Rahman, KM; Sugie, S; Tanaka, T; Yamahara, J | 1 |
| Barczak, AK; Coyle, JT; Luthi-Carter, R; Speno, H | 1 |
| Elia, G; Rossi, A; Santoro, MG | 1 |
| Bryson, H; Bunning, RA; Buttle, DJ; Feltell, R; Kam, CM; Kerrigan, J; Powers, JC | 1 |
| Adler, M; Cornille, F; Hackley, BE; Nicholson, JD | 1 |
| Matsuda, H; Shimoda, H; Yamahara, J; Yoshikawa, M | 3 |
| Deeg, M; Dick, TP; Groll, M; Heinemeyer, W; Huber, R; Keilholz, W; Nussbaum, AK; Rammensee, HG; Schild, H; Schirle, M; Stevanović, S; Wolf, DH | 1 |
| Babu, YS; Jing, H; Kilpatrick, JM; Liu, XY; Moore, D; Narayana, SV; Volanakis, JE | 1 |
| Babu, YS; Chu, N; Cole, LB; Kilpatrick, JM | 1 |
| Aslam, U; Hameed, A; Ying, AJ | 1 |
| Honda, T; Mercken, M; Murayama, M; Murayama, O; Nihonmatsu, N; Omori, A; Saido, TC; Sato, K; Takahashi, H; Takashima, A; Tsubuki, S; Yasutake, K | 1 |
| Conseil, V; Dubremetz, JF; Soête, M | 1 |
| Agata, N; Hirano, S; Ishizuka, M; Isshiki, K; Kumagai, H; Maeda, K; Nakashima, T; Takeuchi, T; Yoshioka, T | 1 |
| Alexanian, AR; Bamburg, JR | 1 |
| Matsuda, H; Shimoda, H; Yoshikawa, M | 1 |
| Kageura, T; Matsuda, H; Shimoda, H; Yoshikawa, M | 1 |
| Howard, LR; Talcott, ST | 1 |
| Fujimaki, T; Fujimoto, H; Okuyama, E; Yamazaki, M | 1 |
| Deutschländer, N; Fink, E; Heitsch, H; Rudolphi, K; Wiemer, G; Wirth, KJ | 1 |
| Andrade, FD; Takahashi, CS; Tavares, DC; Varanda, EA; Vilegas, W | 1 |
| Angeletti, M; Bini, L; Eleuteri, AM; Fioretti, E; Lupidi, G; Tacconi, R | 1 |
| Addonizio, L; Gersony, WM; Hintze, TH; Loke, KE; Mital, S; Slater, JP | 1 |
| Altschuller-Felberg, C; Cardozo, C; Loukissa, A; Nelson, JE | 1 |
| Bogyo, M; Lemberg, MK; Martoglio, B; Ploegh, HL; Weihofen, A | 1 |
| Hasegawa, N; Kimura, Y; Komatsu, N; Muramatsu, T; Oda, T | 1 |
| Bruno, AP; d'Orgeix, AT; Laurent, G; Lautier, D; Quillet-Mary, A | 1 |
| Avenel-Audran, M; Hausen, BM; le Sellin, J; Ledieu, G; Verret, JL | 1 |
| Beckett, MA; Gupta, VK; Hari, DM; Hellman, S; Jaskowiak, NT; Kalluri, R; Koons, AM; Kufe, DW; Mauceri, HJ; Posner, MC; Reimer, C; Salloum, RM; Seetharam, S; Weichselbaum, RR | 1 |
| Faden, AI; Fan, L; Movsesyan, VA; Yakovlev, AG | 1 |
| Hirano, SI; Ishizuka, M; Isshiki, K; Kuboki, H; Kumagai, H; Matsumoto, N; Nakashima, T; Takeuchi, T; Yoshioka, T | 1 |
| Bischoff, A; Cappiello, J; Ghosh, AK | 1 |
| Harvala, C; Kalpoutzakis, E; Magiatis, P; Paraschos, S; Skaltsounis, AL | 1 |
| Agata, N; Bamberg, M; Dickerson, WM; Fram, R; Kalluri, R; Kamphaus, GD; Kharbanda, S; Kufe, D; Milhollen, M; Reimer, CL; Rook, SL; Tammam, JG | 1 |
| Albrecht, RF; Balyasnikova, IV; Danilov, SM; Karran, EH | 1 |
| Reboud-Ravaux, M | 1 |
| Fujimura, S; Hirai, K; Shibata, Y | 1 |
| Kagata, M; Kawamura, M; Masaki, E; Nishi, H | 1 |
| Bucheli, P; Gysler, C; Laloi, M; McCarthy, J; Morandi, O | 1 |
| Mahomed, AS; Rogers, CB; Shode, FO | 1 |
| Kharbanda, S; Kufe, D; Ohno, T; Weichselbaum, R; Yin, L | 1 |
| Wu, G | 1 |
| Eckermann, C; Eckermann, S; Schmidt, J; Schneider, B; Schröder, G; Schröder, J; Strack, D | 1 |
| Isshiki, K; Konuki, K; Kuroda, A; Nagai, H; Nakamura, H; Nakashima, T; Takeuchi, T; Tsuchida, T; Yoshida, M | 1 |
| Czepa, A; Hofmann, T | 1 |
| da Fonseca, LM; Khalil, NM; Kitagawa, RR; Raddi, MS; Vilegas, W | 1 |
| Kim, CH; Kim, JH; Ko, SH; Kwak, YS; Lim, DS; Yoon, WH | 1 |
| Bauta, WE; Burke, BD; Cantrell, WR; Lovett, DP | 1 |
| Hirasawa, A; Shiojima, S; Tsujimoto, G; Yamada, M | 1 |
| IBRAHIM, RK; TOWERS, GH | 2 |
| Kim, CH; Ko, SH; Kwak, YS; Lee, KH; Lee, WY; Lim, DS; Yoon, WH | 1 |
| Andradea, PB; Moreira, MM; Seabra, RM; Silva, AM; Valentão, P | 1 |
| Chen, GQ; Chen, JL; Shen, B; Yu, HF; Yu, XH; Zhu, JS; Zhu, ZM | 1 |
| Berchtold, S; Brand, V; Huber, SM; Lang, F; Lang, KS; Lang, PA; Myssina, S; Sandu, C; Wieder, T | 1 |
| Devienne, KF; Furuya, EM; Raddi, MS; Varanda, EA; Vilegas, W | 1 |
| Saeed, A | 1 |
| Kayaba, S; Nakazawa, T; Ohsawa, K; Takahashi, K; Yasuda, T | 1 |
| De Girolamo, A; Solfrizzo, M; Visconti, A; Vitti, C | 1 |
| Hamada, N; Itoh, A; Nagakura, N; Takenaka, Y; Tanahashi, T | 1 |
| Agata, N; Kharbanda, S; Kufe, D; Milhollen, M; Nogi, H | 1 |
| Roll, DM; Schlingmann, G | 1 |
| Agata, N; Ikeda, D; Ishizuka, M; Isshiki, K; Kumagai, H; Wakazono, K | 1 |
| Bi, XB; Bi, YM; Chen, YT; Xie, JL | 1 |
| Finke, J; Grüllich, C; McGoldrick, S; Zeiser, R | 1 |
| Kiren, S; Shangguan, N; Williams, LJ | 1 |
| Berge, KE; Kulseth, MA; Leren, TP; Ranheim, T; Tveten, K | 1 |
| Dong, ZJ; Jiang, MY; Liu, JK; Liu, R; Niu, Y; Zhang, L; Zhou, ZY; Zhu, YC | 1 |
| Ahn, JS; Bae, K; Choo, SJ; Kim, YH; Ryoo, IJ; Xu, GH; Yoo, ID | 1 |
| Bardos, J; Cano, C; Golding, BT; Griffin, RJ; Hardcastle, IR; Parveen, N; Payne, SL; Peacock, M; Rodriguez-Aristegui, S | 1 |
| Ashraf, Z; Rafique, H; Saeed, A | 1 |
| Gautam, R; Jachak, SM; Kumar, V; Mohan, CG | 1 |
| Chow, WA; Fousek, K; Guan, M; Guo, S; Jiang, C; Shih, CC; Synold, T; Xi, B | 1 |
| Chang, BI; Chen, WS; Cheng, TL; Hsu, FC; Lai, CH; Lin, HY; Liu, SK; Shi, GY; Wu, HL; Wu, YT | 1 |
| Ašler, IL; Luić, M; Pigac, J; Štefanić, Z; Vujaklija, D | 1 |
| Ha, Y; Xue, Y | 1 |
| Boivin, WA; Granville, DJ; Hackett, TL; Knight, DA; Shackleford, M; Vanden Hoek, A; Zhao, H | 1 |
| Biran, A; Krizhanovsky, V; Lowe, SW; Sagiv, A; Simon, J; Yon, M | 1 |
| Allmaier, G; Ašler, IL; Kojić-Prodić, B; Kovačić, F; Marchetti-Deschmann, M; Stefanić, Z | 1 |
| Chen, DD; Miao, F; Qin, BF; Wang, Y; Yang, R; Yang, XJ; Zhou, L | 1 |
| Fa, OY; Ji, TF; Li, J; Liu, H; Su, YL | 1 |
| Valcárcel, J; Vigevani, L | 1 |
| Almstead, NG; Babiak, J; Bhattacharyya, A; Chen, G; Chen, KS; Colacino, JM; Dakka, A; Ebeling, M; Eng, LA; Feng, Z; Fontoura, P; Furia, B; Gabbeta, V; Gerlach, I; Ghosh, A; Haehnke, D; Karp, GM; Ko, CP; Kong, R; Lee, CS; Ling, KK; Lynes, MS; Ma, J; McCarthy, KD; Metzger, F; Moon, YC; Mull, JL; Narasimhan, J; Naryshkin, NA; Paushkin, SV; Peltz, SW; Qi, H; Ratni, H; Risher, N; Rubin, LL; Santarelli, L; Schmucki, R; Sheedy, J; Sivaramakrishnan, M; Trifillis, P; Turpoff, A; Vazirani, P; Weetall, M; Welch, EM; Woll, MG; Zhang, N; Zhang, X; Zhao, X | 1 |
| Cully, M | 1 |
| Ju, Z; Kaliyaperumal, K; Lin, X; Liu, J; Liu, Y; Lu, X; Tian, Y; Tu, Z; Wang, J; Xu, S | 1 |
| Verhelst, SH; Wolf, EV; Zeissler, A | 1 |
| Dalianis, H; Kvist, M; Mowery, D; South, BR; Velupillai, S | 1 |
| Ashton, CM; Bersamin, JB; Blackshear, JE; Bui, LN; Butler, MO; Denison, KI; Graviss, EA; Hai, SA; Johnson, ML; Magtoto, AD; Ochoa, RA; Patel, JG; Pham, VP; Pomer, RM; Sanchez, LR; Shirkey, BA; Swan, JT; Tran, SK; Wray, NP | 1 |
| Fan, XH; Jiang, Z; Liang, QL; Wu, DW; Wu, QN; Yue, W; Zhang, XL | 1 |
| Huang, N; Tian, Y; Wang, J; Xiang, P; Xu, JH; Zhang, M; Zhang, Y | 1 |
| Cheng, J; Cheng, Y; Duan, J; Li, P; Li, R | 1 |
| Abdallah, HM; Almasri, DM; Bagalagel, AA; Ibrahim, SRM; Mohamed, GA; Mohamed, SGA; Noor, AO | 1 |
| Che, Q; Li, C; Li, D; Liu, X; Ma, C; Yu, J; Zhang, G; Zhang, Y; Zhu, T | 1 |
4 review(s) available for isocoumarins and warfarin
| Article | Year |
|---|---|
Allergic contact dermatitis from hydrangea--is it so rare?
Topics: Adult; Agriculture; Allergens; Benzopyrans; Chronic Disease; Coumarins; Dermatitis, Allergic Contact; Dermatitis, Irritant; Dermatitis, Occupational; Diagnosis, Differential; Eczema; Female; France; Hand Dermatoses; Humans; Isocoumarins; Male; Middle Aged; Patch Tests; Plant Leaves; Plant Stems; Rosales | 2000 |
Proteasome inhibitors.
Topics: Acetylcysteine; Animals; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Design; Humans; Hydrolysis; Inflammation; Isocoumarins; Macromolecular Substances; Molecular Weight; Multienzyme Complexes; Neoplasms; Peptides; Proteasome Endopeptidase Complex; Substrate Specificity | 2002 |
Recent Advances in Clinical Natural Language Processing in Support of Semantic Analysis.
Topics: Coumarins; Data Anonymization; Data Collection; Electronic Health Records; Isocoumarins; Natural Language Processing; Semantics | 2015 |
Naturally Occurring Isocoumarins Derivatives from Endophytic Fungi: Sources, Isolation, Structural Characterization, Biosynthesis, and Biological Activities.
Topics: Coumarins; Endophytes; Fungi; Isocoumarins; Metabolomics; Molecular Structure | 2020 |
1 trial(s) available for isocoumarins and warfarin
| Article | Year |
|---|---|
Effect of Chlorhexidine Bathing Every Other Day on Prevention of Hospital-Acquired Infections in the Surgical ICU: A Single-Center, Randomized Controlled Trial.
Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Baths; Catheter-Related Infections; Chlorhexidine; Comorbidity; Coumarins; Cross Infection; Female; Humans; Infection Control; Intensive Care Units; Isocoumarins; Male; Middle Aged; Pneumonia, Ventilator-Associated; Risk Factors; Severity of Illness Index; Surgical Wound Infection; Time Factors | 2016 |
172 other study(ies) available for isocoumarins and warfarin
| Article | Year |
|---|---|
[High-speed liquid chromatographic analysis of drugs. IV. Speration analysis of phyllodulcin and hydrangenol in sweet hydrangea (author's transl)].
Topics: Benzopyrans; Chromatography, High Pressure Liquid; Coumarins; Isocoumarins | 1979 |
Metabolic products of microorganisms. 170. On the antibiotic activity of cladosporin.
Topics: Antifungal Agents; Ascomycota; Bacteria; Chemical Phenomena; Chemistry; Coumarins; Fermentation; Fungi; Isocoumarins; Methylation; Pyrans; Species Specificity; Spores, Fungal | 1978 |
Characterization of serine protease-derived metabolites of big endothelin in the cytosolic fraction from human polymorphonuclear leukocytes.
Topics: Cathepsin G; Cathepsins; Chromatography, High Pressure Liquid; Coumarins; Cytosol; Endothelin-1; Endothelins; Glycine; Humans; Isocoumarins; Leukocyte Elastase; Mass Spectrometry; Neutrophils; Pancreatic Elastase; Protein Precursors; Serine Endopeptidases; Sulfonamides | 1992 |
Biochemical properties of the proteasome from Thermoplasma acidophilum.
Topics: Amino Acid Sequence; Cations, Divalent; Cations, Monovalent; Coumarins; Cysteine Endopeptidases; Enzyme Activation; Hydrogen-Ion Concentration; Isocoumarins; Isoelectric Point; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Peptides; Proteasome Endopeptidase Complex; Serpins; Temperature; Thermoplasma | 1992 |
Use of serine-protease inhibitors as probes for the different proteolytic activities of the rat liver multicatalytic proteinase complex.
Topics: Amino Acid Sequence; Animals; Coumarins; Cysteine Endopeptidases; Isocoumarins; Isoflurophate; Kinetics; Liver; Molecular Sequence Data; Multienzyme Complexes; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Substrate Specificity; Trypsin | 1992 |
NG-011 and NG-012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties.
Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Coumarins; Isocoumarins; Lactones; Nerve Growth Factors; Neurites; PC12 Cells; Penicillium; Phenols; Rats | 1992 |
Thunberginols A, B, and F, new antiallergic and antimicrobial principles from hydrangeae dulcis folium.
Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae; Benzofurans; Benzopyrans; Benzoquinones; Bronchoconstriction; Coumarins; Guinea Pigs; In Vitro Techniques; Isocoumarins; Microbial Sensitivity Tests; Passive Cutaneous Anaphylaxis; Plant Extracts; Plants, Medicinal | 1992 |
A 3,4-dichloroisocoumarin-resistant component of the multicatalytic proteinase complex.
Topics: Amino Acid Sequence; Animals; Cattle; Coumarins; Cysteine Endopeptidases; Drug Resistance; Isocoumarins; Kinetics; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Pituitary Gland; Protease Inhibitors; Proteasome Endopeptidase Complex; Substrate Specificity | 1992 |
Effect of the 7-amino substituent on the inhibitory potency of mechanism-based isocoumarin inhibitors for porcine pancreatic and human neutrophil elastases: a 1.85-A X-ray structure of the complex between porcine pancreatic elastase and 7-[(N-tosylphenyla
Topics: Animals; Coumarins; Crystallography; Humans; Isocoumarins; Kinetics; Leukocyte Elastase; Pancreatic Elastase; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Swine | 1992 |
3,4-dichloroisocoumarin-induced activation of the degradation of beta-casein by the bovine pituitary multicatalytic proteinase complex.
Topics: Amino Acid Sequence; Animals; Binding Sites; Caseins; Catalysis; Cattle; Chromatography, Gel; Coumarins; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrolysis; Isocoumarins; Molecular Sequence Data; Multienzyme Complexes; Phosphorylation; Pituitary Gland; Proteasome Endopeptidase Complex; Serine Proteinase Inhibitors | 1992 |
Peptidylglutamyl-peptide hydrolase activity of the multicatalytic proteinase complex: evidence for a new high-affinity site, analysis of cooperative kinetics, and the effect of manganese ions.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cations, Divalent; Coumarins; Cysteine Endopeptidases; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Isocoumarins; Liver; Metals; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Potassium Chloride; Protease Inhibitors; Proteasome Endopeptidase Complex; Rats; Rats, Inbred Strains | 1992 |
A natural killer cell granule protein that induces DNA fragmentation and apoptosis.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Death; Chromatography, Gel; Coumarins; Deoxyribonucleases; DNA Damage; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Granzymes; Isocoumarins; Killer Cells, Natural; Molecular Sequence Data; Rats; Rats, Inbred F344; Sequence Homology, Nucleic Acid; Serine Endopeptidases; Serine Proteinase Inhibitors; Tumor Cells, Cultured | 1992 |
Hydrangenol, a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae).
Topics: Animals; Benzopyrans; Chromatography, Thin Layer; Coumarins; Dermatitis, Contact; Female; Guinea Pigs; Irritants; Isocoumarins; Plants | 1991 |
6-Hydroxymellein synthetase as a multifunctional enzyme complex in elicitor-treated carrot root extract.
Topics: Acyl Carrier Protein; Acyltransferases; Chromatography, Gel; Coumarins; Cross Reactions; Escherichia coli; Fatty Acid Synthases; Immunoblotting; Isocoumarins; Ligases; Multienzyme Complexes; Oxidoreductases; Plants | 1991 |
Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex.
Topics: Amino Acid Sequence; Animals; Binding Sites; Coumarins; Isocoumarins; Kinetics; Models, Molecular; Molecular Sequence Data; Pancreas; Pancreatic Elastase; Protein Binding; Protein Conformation; Structure-Activity Relationship; Swine; X-Ray Diffraction | 1991 |
Cytogenin, a novel antitumor substance.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Cells, Cultured; Coumarins; Female; Interleukin-1; Isocoumarins; Macrophages; Mice; Mice, Inbred ICR; Streptomycetaceae; Tumor Cells, Cultured | 1990 |
Characterization of the active site of human multicatalytic proteinase.
Topics: Amino Acid Sequence; Binding Sites; Chromatography, Ion Exchange; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Isocoumarins; Isoflurophate; Kinetics; Liver; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Sulfhydryl Reagents | 1990 |
Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin.
Topics: Amino Acid Sequence; Animals; Binding Sites; Coumarins; Indicators and Reagents; Isocoumarins; Models, Molecular; Molecular Sequence Data; Molecular Structure; Pancreas; Pancreatic Elastase; Protein Binding; Protein Conformation; Structure-Activity Relationship; Swine; X-Ray Diffraction | 1990 |
In vivo determination of the anticoagulant effect of a substituted isocoumarin (ACITIC).
Topics: Animals; Anticoagulants; Coumarins; Dose-Response Relationship, Drug; Infusions, Intravenous; Isocoumarins; Partial Thromboplastin Time; Rabbits | 1990 |
3,4-Dichloroisocoumarin, a serine protease inhibitor, inactivates glycogen phosphorylase b.
Topics: Animals; Coumarins; In Vitro Techniques; Isocoumarins; Muscles; Phosphorylases; Rabbits; Serine Proteinase Inhibitors | 1990 |
Inhibitory effects of hydrangenol derivatives on the activation of hyaluronidase and their antiallergic activities.
Topics: Animals; Benzopyrans; Coumarins; Histamine Release; Hyaluronoglucosaminidase; In Vitro Techniques; Isocoumarins; Mast Cells; Passive Cutaneous Anaphylaxis; Rats; Structure-Activity Relationship | 1988 |
Pituitary multicatalytic proteinase complex. Specificity of components and aspects of proteolytic activity.
Topics: Amino Acid Sequence; Animals; Cattle; Chymotrypsin; Coumarins; Cysteine Endopeptidases; Endopeptidases; Enzyme Activation; Fatty Acids; Heparin; Immune Sera; Isocoumarins; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Phosphorylation; Pituitary Gland; Proteasome Endopeptidase Complex; Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors; Sodium Dodecyl Sulfate; Substrate Specificity; Trypsin | 1989 |
[Studies on the structure of a new isocoumarin glucoside of the root sprouts of Agrimonia pilosa Ledeb].
Topics: Chemical Phenomena; Chemistry; Coumarins; Drugs, Chinese Herbal; Glucosides; Glycosides; Isocoumarins | 1989 |
Baciphelacin: a new eukaryotic translation inhibitor.
Topics: Anti-Bacterial Agents; Cell-Free System; Coumarins; DNA; Eukaryotic Cells; HeLa Cells; Humans; Isocoumarins; Protein Biosynthesis | 1987 |
Allergic contact dermatitis to hydrangea.
Topics: Allergens; Benzopyrans; Coumarins; Dermatitis, Contact; Humans; Isocoumarins; Plants | 1987 |
Ulcerogenic and antiulcerogenic effects of a new antiinflammatory drug, the gamma-lactone-N-ethyl derivative of 6-[1S-(3S,4-dihydro-8-hydroxy-1H-2-benzo- pyran-1-one-3-yl)-3-methylbutylamino]-4S,5S-dihydroxy-6-oxo-3S- ammoniohexanoate, on gastrointestinal
Topics: Animals; Anti-Ulcer Agents; Aspirin; Coumarins; Gastrointestinal Motility; Indomethacin; Isocoumarins; Male; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer | 1986 |
Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor.
Topics: Animals; Blood Coagulation Factors; Cattle; Coumarins; Humans; Isocoumarins; Kinetics; Leukocytes; Mast Cells; Models, Chemical; Pancreatic Elastase; Protease Inhibitors; Rats; Serine Endopeptidases; Structure-Activity Relationship; Swine | 1985 |
1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Bacillus; Chromatography, High Pressure Liquid; Coumarins; Isocoumarins; Peptic Ulcer; Rats; Solubility; Structure-Activity Relationship | 1985 |
[The quantitative analysis of phyllodulcin in "Amacha" (sweet hydrangea) by means of thin-layer chromatography (author's transl)].
Topics: Chromatography, Thin Layer; Coumarins; Isocoumarins; Plants | 1974 |
Chemical constituents of gentianaceae. IX. Natural occurrence of erythrocentaurin in Enicostemma hyssopifolium and Swertia lawii.
Topics: Coumarins; Formaldehyde; Isocoumarins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1974 |
1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammon
Topics: Animals; Coumarins; Drug Evaluation, Preclinical; Indicators and Reagents; Isocoumarins; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Methods; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Stomach Ulcer; Structure-Activity Relationship | 1983 |
Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds.
Topics: Antifungal Agents; Coumarins; Isocoumarins | 1981 |
Structure-taste correlations in sweet dihydrochalcone, sweet dihydroisocoumarin, and bitter flavone compounds.
Topics: Chalcone; Chalcones; Chemical Phenomena; Chemistry, Physical; Coumarins; Crystallization; Crystallography, X-Ray; Flavones; Flavonoids; Isocoumarins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship; Sweetening Agents; Taste; Thermodynamics | 1995 |
Complexes between serpins and inactive proteinases are not thermodynamically stable but are recognized by serpin receptors.
Topics: alpha-2-Antiplasmin; Amino Acid Sequence; Animals; Chymotrypsin; Coumarins; Endopeptidases; Enzyme Stability; Humans; Isocoumarins; Leukocyte Elastase; Mice; Molecular Sequence Data; Pancreatic Elastase; Protein Conformation; Receptors, Cell Surface; Serpins; Thermodynamics | 1994 |
Development of bioactive functions in hydrangeae dulcis folium. III. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (1). Thunberginols A, B, and F.
Topics: Animals; Anti-Bacterial Agents; Benzofurans; Coumarins; Guinea Pigs; Histamine Release; In Vitro Techniques; Isocoumarins; Magnetic Resonance Spectroscopy; Male; Microbial Sensitivity Tests; Plant Extracts; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar | 1994 |
Porcine aortic smooth muscle cells secrete a serine protease for insulin-like growth factor binding protein-2.
Topics: Animals; Aorta; Aprotinin; Arteriosclerosis; Carrier Proteins; Cells, Cultured; Chromatography; Coumarins; Culture Media; Edetic Acid; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Isocoumarins; Muscle, Smooth, Vascular; Peptide Hydrolases; Serine Endopeptidases; Serine Proteinase Inhibitors; Somatomedins; Swine | 1995 |
Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes.
Topics: Antigens, Surface; Apoptosis; Caspase 1; Cell Line; Cell Nucleus; Cell-Free System; Coumarins; Cysteine Endopeptidases; Endopeptidases; fas Receptor; Humans; Isocoumarins; T-Lymphocytes; Tosylphenylalanyl Chloromethyl Ketone | 1995 |
Inhibition of a tumour protease with 3,4-dichloroisocoumarin, pentamidine-isethionate and guanidino derivatives.
Topics: Benzoates; Binding, Competitive; Carboxylic Ester Hydrolases; Carcinoma, Squamous Cell; Cell Membrane; Coumarins; Dexamethasone; Endopeptidases; Guanidines; Humans; Isocoumarins; Kinetics; Lung Neoplasms; Medroxyprogesterone; Microscopy, Fluorescence; Pentamidine; Protease Inhibitors; Sodium Dodecyl Sulfate; Sulfaguanidine | 1994 |
[Effects of thunberginol A contained in Hydrangeae dulcis forium on types I-IV allergies].
Topics: Administration, Oral; Animals; Coumarins; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immune Complex Diseases; Isocoumarins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Rabbits; Rats; Rats, Wistar | 1995 |
Low molecular weight immunomodulators produced by microorganisms.
Topics: Actinobacteria; Adjuvants, Immunologic; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Biological Factors; Cell Adhesion; Coumarins; Cytokines; Drug Screening Assays, Antitumor; Extracellular Matrix; Hematopoiesis; Immunosuppressive Agents; Indoles; Isocoumarins; Lactams; Mice; Peptides; Pyrrolidinones; Serine; T-Lymphocytes; Tetrahydronaphthalenes; Time Factors | 1995 |
Differences in catalytic activities and subunit pattern of multicatalytic proteinase complexes (proteasomes) isolated from bovine pituitary, lung, and liver. Changes in LMP7 and the component necessary for expression of the chymotrypsin-like activity.
Topics: Amino Acid Sequence; Animals; Catalysis; Cattle; Chymotrypsin; Coumarins; Cysteine Endopeptidases; Isocoumarins; Liver; Lung; Molecular Sequence Data; Multienzyme Complexes; Pituitary Gland; Proteasome Endopeptidase Complex; Proteins | 1995 |
Antitumor activity of cytogenin.
Topics: Animals; Antibiotics, Antineoplastic; Coumarins; Female; Isocoumarins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental | 1995 |
Interleukin 1-induced phosphorylation of MAD3, the major inhibitor of nuclear factor kappa B of HeLa cells. Interference in signalling by the proteinase inhibitors 3,4-dichloroisocoumarin and tosylphenylalanyl chloromethylketone.
Topics: Base Sequence; Chromatography, Ion Exchange; Coumarins; DNA-Binding Proteins; Heat-Shock Proteins; HeLa Cells; Humans; I-kappa B Proteins; Interleukin-1; Isocoumarins; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Transcription Factor RelB; Transcription Factors | 1995 |
Proteasome from Thermoplasma acidophilum: a threonine protease.
Topics: Amino Acid Sequence; Archaeal Proteins; Binding Sites; Coumarins; Endopeptidases; Hydrogen-Ion Concentration; Isocoumarins; Molecular Sequence Data; Mutagenesis; Protein Folding; Sequence Alignment; Serine Proteinase Inhibitors; Thermoplasma | 1995 |
Proteinases are involved in both DNA fragmentation and membrane damage during CTL-mediated target cell killing.
Topics: Animals; Arginine; Aurintricarboxylic Acid; Cells, Cultured; Coumarins; Cytotoxicity, Immunologic; DNA; Endopeptidases; Isocoumarins; Kinetics; Mast-Cell Sarcoma; Mice; Mice, Inbred BALB C; Protease Inhibitors; Substrate Specificity; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured; Tyrosine | 1995 |
Action of cytogenin on lymphoid cells and their cytokine production.
Topics: Animals; Anions; Cells, Cultured; Coumarins; Cytokines; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon-gamma; Interleukin-1; Isocoumarins; Macrophages; Mice; Phagocytosis; Superoxides; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1995 |
Modulation of macrophage activity in tumor bearing mice by cytogenin.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Cell Division; Concanavalin A; Coumarins; Female; Isocoumarins; Macrophages; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Neoplasms, Experimental; Nitric Oxide; Spleen | 1995 |
Effects of cytogenin, a novel anti-arthritic agent, on type II collagen-induced arthritis in DBA/1J mice and adjuvant arthritis in Lewis rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Arthritis, Experimental; Carrageenan; Collagen; Coumarins; Edema; Female; Isocoumarins; Male; Mice; Mice, Inbred DBA; Rats; Rats, Inbred Lew | 1994 |
Sodium dodecyl sulfate-stable complexes between serpins and active or inactive proteinases contain the region COOH-terminal to the reactive site loop.
Topics: Animals; Binding Sites; Coumarins; Electrophoresis, Polyacrylamide Gel; Isocoumarins; Kinetics; Protein Binding; Protein Structure, Secondary; Serine; Serine Proteinase Inhibitors; Serpins; Sodium Dodecyl Sulfate; Swine; Trypsin | 1995 |
Downregulation of neutrophil CD43 by opsonized zymosan.
Topics: Antigens, CD; Coumarins; Down-Regulation; Endopeptidases; Humans; Isocoumarins; Isoflurophate; Leukosialin; Neutrophils; Opsonin Proteins; Respiratory Burst; Sialoglycoproteins; Sulfones; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1995 |
Chemical reactivity of the toxin oosponol from Gloeophyllum abietinum with nucleophilic agents.
Topics: Anti-Bacterial Agents; Coumarins; Glutathione; Isocoumarins; Magnetic Resonance Spectroscopy; Mercaptoethanol; Models, Molecular; Oxidation-Reduction; Polyporaceae; Spectrophotometry, Ultraviolet | 1994 |
[Chemical constituents of Hydrangea macrophylla (Thunb.) Ser].
Topics: Benzopyrans; Coumarins; Galactosides; Glucosides; Isocoumarins; Molecular Structure; Plant Leaves; Plants; Sweetening Agents | 1994 |
Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor.
Topics: Animals; Cell Line; Coumarins; Female; Humans; Interleukins; Isocoumarins; Macrophages; Metalloendopeptidases; Mice; Mice, Inbred C3H; Monocytes; Phenylalanine; Protein Processing, Post-Translational; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Human granzyme B is essential for DNA fragmentation of susceptible target cells.
Topics: Animals; Aurintricarboxylic Acid; Blotting, Northern; Blotting, Western; Cell Survival; Chymases; Coumarins; Cytoplasmic Granules; Cytotoxicity, Immunologic; DNA; Egtazic Acid; Granzymes; Humans; Isocoumarins; Killer Cells, Natural; Mice; Serine Endopeptidases; Sulfones; Tumor Cells, Cultured | 1994 |
Mechanism-based isocoumarin inhibitors for blood coagulation serine proteases. Effect of the 7-substituent in 7-amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on inhibitory and anticoagulant potency.
Topics: Amino Acid Sequence; Animals; Anticoagulants; Binding Sites; Blood Coagulation; Cattle; Coumarins; Factor IXa; Factor VIIIa; Humans; Hydrolysis; Isocoumarins; Liposomes; Models, Molecular; Molecular Sequence Data; Molecular Structure; Serine Proteinase Inhibitors; Swine; Thrombin | 1994 |
[Quantitative analysis of dihydroisocoumarin constituents of Hydrangeae Dulcis Folium by means of high performance liquid chromatography. Chemical characterization of the processing, distribution in plant, and seasonal fluctuation].
Topics: Benzopyrans; Chromatography, High Pressure Liquid; Coumarins; Isocoumarins; Japan; Plant Extracts; Plants, Medicinal; Seasons | 1994 |
Biosynthesis of antitumor antibiotic, cytogenin.
Topics: Acetates; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Coumarins; Culture Media; Hydroxylation; Isocoumarins; Magnetic Resonance Spectroscopy; Methionine; Methylation; Prodrugs; Spectrophotometry, Ultraviolet; Streptomycetaceae | 1994 |
Isocladosporin, a biologically active isomer of cladosporin from Cladosporium cladosporioides.
Topics: Cladosporium; Coumarins; Isocoumarins; Mass Spectrometry; Molecular Conformation; Mycotoxins; Spectrophotometry, Ultraviolet; Stereoisomerism; Triticum | 1993 |
Stimulation of calcium influx and calcium cascade by cyclic AMP in cultured carrot cells.
Topics: Adenylyl Cyclases; Bucladesine; Calcium; Calmodulin; Cell Membrane; Cells, Cultured; Cholera Toxin; Colforsin; Coumarins; Cyclic AMP; Cytosol; Enzyme Activation; Isocoumarins; Plants; Protein Kinases | 1993 |
The receptor-destroying enzyme of influenza C virus is required for entry into target cells.
Topics: Acetylesterase; Animals; Blotting, Northern; Cell Line; Coumarins; Dogs; Gammainfluenzavirus; Hemagglutinins, Viral; Hemolysis; Humans; Influenza A virus; Isocoumarins; Isoflurophate; Kidney; Kinetics; RNA, Viral; Serine Proteinase Inhibitors; Viral Fusion Proteins; Viral Proteins | 1993 |
Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids.
Topics: Amino Acid Sequence; Animals; Calcium; Cattle; Chymotrypsin; Coumarins; Cysteine Endopeptidases; Isocoumarins; Kinetics; Lauric Acids; Magnesium; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Pituitary Gland; Protease Inhibitors; Proteasome Endopeptidase Complex; Serine Proteinase Inhibitors; Sodium Dodecyl Sulfate; Substrate Specificity; Trypsin | 1993 |
Serine protease inhibitors block priming of monocytes for enhanced release of superoxide.
Topics: Cell Culture Techniques; Coumarins; Dose-Response Relationship, Drug; Humans; Isocoumarins; Kinetics; Lipopolysaccharides; Monocytes; Serine Proteinase Inhibitors; Sulfonamides; Sulfones; Superoxides; Tumor Necrosis Factor-alpha | 1995 |
Antioxidants differentially affect nuclear factor kappa B-mediated nitric oxide synthase expression in vascular smooth muscle cells.
Topics: Animals; Antioxidants; Aorta, Thoracic; Base Sequence; Cells, Cultured; Chromonar; Coumarins; DNA; Flavonoids; Gene Expression; Isocoumarins; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide Synthase; Rats; Rats, Wistar; Serotonin | 1996 |
Activation of the multicatalytic endopeptidase by oxidants. Effects on enzyme structure.
Topics: Amino Acid Sequence; Animals; Chickens; Chloromercuribenzoates; Coumarins; Cysteine Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Hydrogen Peroxide; Hydrolysis; Iron; Isocoumarins; Male; Molecular Sequence Data; Multienzyme Complexes; Oxidants; p-Chloromercuribenzoic Acid; Peptides; Proteasome Endopeptidase Complex; Protein Conformation; Proteins; Serine Proteinase Inhibitors | 1996 |
Proteinases in renal cell death.
Topics: Animals; Anti-Bacterial Agents; Antimycin A; Antipain; Carboxypeptidases; Cathepsin A; Cathepsin B; Cell Death; Coumarins; Cysteine; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Endopeptidases; Hydrocarbons, Fluorinated; Hydroquinones; Isocoumarins; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Leucine; Leupeptins; Lysosomes; Membrane Potentials; Pepstatins; Peroxides; Rabbits; Reactive Oxygen Species; Serine Proteinase Inhibitors; tert-Butylhydroperoxide; Tosyllysine Chloromethyl Ketone | 1996 |
4-Chloro-7-(iodoacetyl)amino-3-methoxy-isocoumarin.
Topics: Coumarins; Crystallography, X-Ray; Isocoumarins; Molecular Conformation | 1996 |
Prolyl aminopeptidase is also present in Enterobacteriaceae: cloning and sequencing of the Hafnia alvei enzyme-gene and characterization of the expressed enzyme.
Topics: Aeromonas; Amino Acid Sequence; Aminopeptidases; Bacillus; Base Sequence; Chloromercuribenzoates; Cloning, Molecular; Coumarins; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Enterobacteriaceae; Gene Expression Regulation, Enzymologic; Isocoumarins; Lactobacillus; Molecular Sequence Data; Neisseria; Open Reading Frames; p-Chloromercuribenzoic Acid; Restriction Mapping; Substrate Specificity | 1996 |
Effects of cytogenin on spontaneous arthritis in MRL/1 mice and on pristane-induced arthritis (PIA) in DBA/1J mice.
Topics: Animals; Arthritis; Coumarins; Isocoumarins; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Terpenes | 1995 |
Calpain inhibitors and serine protease inhibitors can produce apoptosis in HL-60 cells.
Topics: Apoptosis; Calpain; Coumarins; Cycloheximide; Cysteine Proteinase Inhibitors; Diazomethane; HL-60 Cells; Humans; Isocoumarins; Leupeptins; Oligopeptides; Protein Synthesis Inhibitors; Serine Proteinase Inhibitors | 1996 |
Purification, kinetical and molecular characterizations of a serine collagenolytic protease from greenshore crag (Carcinus maenas) digestive gland.
Topics: alpha 1-Antitrypsin; Amino Acid Sequence; Animals; Brachyura; Coumarins; Digestive System; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isocoumarins; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Oligopeptides; Serine Proteinase Inhibitors; Tosyl Compounds; Trypsin Inhibitor, Bowman-Birk Soybean | 1996 |
Development of bioactive functions in Hydrangeae dulcis folium. VI. Syntheses of thunberginols A and F and their 3'-deoxy-derivatives using regiospecific lactonization of stilbene carboxylic acid: structures and inhibitory activity on histamine release of
Topics: Animals; Anti-Allergic Agents; Anti-Infective Agents; Benzofurans; Coumarins; Exudates and Transudates; Histamine Release; Isocoumarins; Lactones; Magnetic Resonance Spectroscopy; ortho-Aminobenzoates; Plants, Medicinal; Rats | 1996 |
Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate.
Topics: Acetylcysteine; Adenosine Triphosphate; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Endoplasmic Reticulum; Fungal Proteins; Genes, Fungal; Isocoumarins; Kinetics; Microsomes; Multienzyme Complexes; Proteasome Endopeptidase Complex; Saccharomyces cerevisiae; Substrate Specificity | 1996 |
Apparent formation of sodium dodecyl sulfate-stable complexes between serpins and 3,4-dichloroisocoumarin-inactivated proteinases is due to regeneration of active proteinase from the inactivated enzyme.
Topics: Animals; Cattle; Coumarins; Endopeptidases; Enzyme Activation; Humans; Isocoumarins; Serine Proteinase Inhibitors; Serpins; Sodium Dodecyl Sulfate | 1997 |
Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin.
Topics: Antibiotics, Antineoplastic; Antipain; Apoptosis; Ceramides; Coumarins; Daunorubicin; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; HL-60 Cells; Humans; Hydrolysis; Isocoumarins; Leupeptins; NF-kappa B; Pepstatins; Protease Inhibitors; Serine Proteinase Inhibitors; Signal Transduction; Sphingomyelin Phosphodiesterase; Sphingomyelins; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured | 1997 |
Induction of nuclear factor kappa B/Rel nuclear activity in human peripheral blood T lymphocytes by anti-HLA class I monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; COS Cells; Coumarins; Gene Expression Regulation; Histocompatibility Antigens Class I; Humans; Isocoumarins; Kinetics; NF-kappa B; NF-kappa B p50 Subunit; Nuclear Proteins; Rabbits; Serine Proteinase Inhibitors; T-Lymphocytes; Transcription Factor RelA | 1997 |
Mutagenic and cytotoxic activity of an isocoumarin (Paepalantine) isolated from Paepalanthus vellozioides.
Topics: Animals; Anti-Bacterial Agents; Cell Division; Cell Survival; CHO Cells; Chromosome Aberrations; Coumarins; Cricetinae; Dose-Response Relationship, Drug; Humans; Isocoumarins; Mutagenicity Tests; Plant Extracts; Plants; Salmonella typhimurium | 1997 |
Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Camptothecin; Caspase 3; Caspases; Cell Nucleus; Cell-Free System; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Gene Deletion; Genes, p53; HL-60 Cells; Humans; Isocoumarins; Lamin Type B; Lamins; Nuclear Proteins; Poly Adenosine Diphosphate Ribose; Prodrugs; Serine Endopeptidases; Serine Proteinase Inhibitors; Tumor Suppressor Protein p53 | 1997 |
Granzyme B independently of perforin mediates noncytolytic intracellular inactivation of vesicular stomatitis virus.
Topics: Apoptosis; Cells, Cultured; Coumarins; Cytotoxicity, Immunologic; DNA Damage; Granzymes; Humans; Isocoumarins; Killer Cells, Lymphokine-Activated; Membrane Glycoproteins; Perforin; Pore Forming Cytotoxic Proteins; RNA, Messenger; RNA, Viral; Serine Endopeptidases; Serine Proteinase Inhibitors; Vesicular stomatitis Indiana virus; Virus Cultivation | 1997 |
Reactions of [14C]-3,4-dichloroisocoumarin with subunits of pituitary and spleen multicatalytic proteinase complexes (proteasomes).
Topics: Animals; Carbon Radioisotopes; Catalysis; Cattle; Coumarins; Cysteine Endopeptidases; Isocoumarins; Multienzyme Complexes; Pituitary Gland; Proteasome Endopeptidase Complex; Proteins; Serine Proteinase Inhibitors; Spleen; Viral Matrix Proteins | 1997 |
Lamin B phosphorylation by protein kinase calpha and proteolysis during apoptosis in human leukemia HL60 cells.
Topics: Amino Acid Sequence; Apoptosis; Camptothecin; Cell Nucleus; Coumarins; Cytosol; DNA Fragmentation; HL-60 Cells; Humans; Isocoumarins; Isoenzymes; Kinetics; Lamin Type B; Lamins; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Secondary; Serine Proteinase Inhibitors; Time Factors; Topoisomerase I Inhibitors; Tumor Suppressor Protein p53 | 1998 |
Neutral endopeptidase and angiotensin-converting enzyme inhibitors increase nitric oxide production in isolated canine coronary microvessels by a kinin-dependent mechanism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Coumarins; Dogs; Drug Interactions; Glycopeptides; In Vitro Techniques; Isocoumarins; Neprilysin; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Protease Inhibitors; Ramipril; Serine Proteinase Inhibitors; Thiorphan | 1998 |
Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azo Compounds; Benzopyrans; Colonic Neoplasms; Coumarins; Diet; Intestinal Neoplasms; Isocoumarins; Male; Naphthoquinones; Rats; Rats, Inbred F344 | 1998 |
Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II.
Topics: Animals; Antigens, Surface; Binding, Competitive; Carboxypeptidases; Chelating Agents; Cloning, Molecular; Cobalt; Coumarins; Dipeptides; Edetic Acid; Folic Acid; Glutamate Carboxypeptidase II; Histamine H1 Antagonists; Humans; Hydrolysis; Isocoumarins; Kinetics; Leucine; Male; Neuropeptides; Pepstatins; Phenanthrolines; Prostatic Neoplasms; Protease Inhibitors; Rats; Serine Proteinase Inhibitors; Substrate Specificity; Synaptic Transmission; Tumor Cells, Cultured | 1998 |
Activation of the heat shock factor 1 by serine protease inhibitors. An effect associated with nuclear factor-kappaB inhibition.
Topics: Coumarins; DNA; DNA-Binding Proteins; Down-Regulation; Heat Shock Transcription Factors; Heat-Shock Proteins; Humans; Isocoumarins; Jurkat Cells; NF-kappa B; Serine Proteinase Inhibitors; Transcription Factors | 1998 |
A serine proteinase inactivator inhibits chondrocyte-mediated cartilage proteoglycan breakdown occurring in response to proinflammatory cytokines.
Topics: Animals; Cartilage; Cattle; Chondrocytes; Coumarins; Culture Media; Culture Techniques; Cytokines; Humans; Inflammation Mediators; Isocoumarins; Kinetics; Proteoglycans; Serine Endopeptidases; Serine Proteinase Inhibitors; Urokinase-Type Plasminogen Activator | 1998 |
Efficacy of a novel metalloprotease inhibitor on botulinum neurotoxin B activity.
Topics: Botulinum Toxins; Botulinum Toxins, Type A; Captopril; Coumarins; Dose-Response Relationship, Drug; Isocoumarins; Metalloendopeptidases; Protease Inhibitors; Spectrometry, Fluorescence; Zinc | 1998 |
Development of bioactive functions in Hydrangeae Dulcis Folium. VII. Immunomodulatory activities of thunberginol A and related compounds on lymphocyte proliferation.
Topics: Animals; Coumarins; Female; Immunosuppressive Agents; Isocoumarins; L-Lactate Dehydrogenase; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Plant Extracts | 1998 |
Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Coumarins; Cysteine Endopeptidases; Fluorescence; Fungal Proteins; Histocompatibility Antigens Class I; Isocoumarins; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Peptides; Proteasome Endopeptidase Complex; Saccharomyces cerevisiae; Substrate Specificity; Vertebrates | 1998 |
Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
Topics: Binding Sites; Complement Factor D; Coumarins; Crystallography, X-Ray; Enzyme Inhibitors; Histidine; Isocoumarins; Models, Molecular; Oxazines; Protein Conformation; Serine Endopeptidases; Serine Proteinase Inhibitors; Water | 1998 |
Structure of 3,4-dichloroisocoumarin-inhibited factor D.
Topics: Animals; Benzoxazines; Carbamates; Complement Factor D; Complement Pathway, Alternative; Coumarins; Crystallization; Crystallography, X-Ray; Humans; Isocoumarins; Models, Molecular; Molecular Sequence Data; Oxazines; Pancreatic Elastase; Protein Conformation; Serine Proteinase Inhibitors; Swine | 1998 |
3,4-Dichloroisocoumarin serine protease inhibitor induces DNA fragmentation and apoptosis in susceptible target cells.
Topics: 3T3 Cells; Animals; Apoptosis; Coumarins; DNA Damage; Humans; Isocoumarins; Killer Cells, Lymphokine-Activated; Mice; Microscopy, Electron; Serine Proteinase Inhibitors | 1998 |
Immunomodulatory activity of thunberginol A and related compounds isolated from Hydrangeae Dulcis Folium on splenocyte proliferation activated by mitogens.
Topics: Adjuvants, Immunologic; Animals; Anti-Allergic Agents; Cell Division; Coumarins; Female; In Vitro Techniques; Isocoumarins; Mice; Mice, Inbred C57BL; Mitogens; Plant Leaves; Plants, Medicinal; Spleen; T-Lymphocytes | 1998 |
Dual roles of proteasome in the metabolism of presenilin 1.
Topics: Acetylcysteine; Alzheimer Disease; Amino Acid Sequence; Brain Chemistry; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Glycoproteins; Humans; Isocoumarins; Kidney; Membrane Proteins; Molecular Sequence Data; Multienzyme Complexes; Mutation; Neuroblastoma; Peptide Fragments; Precipitin Tests; Presenilin-1; Proteasome Endopeptidase Complex; Serine Proteinase Inhibitors; Sulfones; Trypsin Inhibitors; Tumor Cells, Cultured | 1999 |
Serine protease inhibitors block invasion of host cells by Toxoplasma gondii.
Topics: Animals; Chlorocebus aethiops; Coumarins; Isocoumarins; Serine Endopeptidases; Serine Proteinase Inhibitors; Sulfones; Toxoplasma; Vero Cells | 1999 |
Inhibition of angiogenesis by a new isocoumarin, NM-3.
Topics: Animals; Anticoagulants; Antineoplastic Agents; Coumarins; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Female; Isocoumarins; Mice; Mice, Inbred ICR; Neovascularization, Pathologic; Sarcoma 180; Tumor Cells, Cultured | 1999 |
Components of the bovine pituitary multicatalytic proteinase complex (proteasome) cleaving bonds after hydrophobic residues.
Topics: Acetylcysteine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Cattle; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Hydrolysis; Insulin; Isocoumarins; Kinetics; Lactams; Molecular Sequence Data; Multienzyme Complexes; Pituitary Gland; Proteasome Endopeptidase Complex | 1999 |
Neuronal survival activity of s100betabeta is enhanced by calcineurin inhibitors and requires activation of NF-kappaB.
Topics: Animals; Antioxidants; Brain Chemistry; Calcineurin Inhibitors; Calcium-Binding Proteins; Cattle; Cell Nucleus; Cell Survival; Cells, Cultured; Chick Embryo; Coumarins; Cyclosporine; Dexamethasone; Dimerization; Immunophilins; Immunosuppressive Agents; Isocoumarins; Macromolecular Substances; Nerve Growth Factors; Neurons; NF-kappa B; Prosencephalon; Pyrethrins; Pyrrolidines; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Serine Proteinase Inhibitors; Sirolimus; Tacrolimus; Thiocarbamates | 1999 |
Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells.
Topics: Animals; Antigen-Antibody Reactions; Benzofurans; Benzopyrans; Bibenzyls; Calcimycin; Coumarins; Histamine Release; Immunoglobulin E; Inhibitory Concentration 50; Ionophores; Isocoumarins; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneum; Phenols; Phthalic Acids; Plant Leaves; Plants, Medicinal; Rats; Rats, Wistar; Stilbenes; Structure-Activity Relationship | 1999 |
Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats.
Topics: Animals; Benzofurans; Benzopyrans; Coumarins; Glucosides; Isocoumarins; Male; Passive Cutaneous Anaphylaxis; Plants, Medicinal; Rats; Rats, Wistar | 1999 |
The role of thunberginol A, an isocoumarin constituent of Hydrangeae Dulcis Folium, on the signal transmission pathway for rat mast cell degranulation.
Topics: Animals; Calcium; Cattle; Cell Degranulation; Cell Membrane; Coumarins; Cytoskeleton; Erythrocytes; Hemolysis; In Vitro Techniques; Isocoumarins; Magnoliopsida; Mast Cells; Phosphorylation; Plant Extracts; Rats; Signal Transduction; Tyrosine | 1999 |
Determination and distribution of 6-methoxymellein in fresh and processed carrot puree by a rapid spectrophotometric assay.
Topics: Anti-Infective Agents; Coumarins; Daucus carota; Food Handling; Hot Temperature; Isocoumarins; Spectrophotometry, Ultraviolet | 1999 |
Immunomodulatory constituents from an ascomycete, Microascus tardifaciens.
Topics: Anthracenes; Anthraquinones; Ascomycota; Coumarins; Drugs, Chinese Herbal; Emodin; Immunosuppressive Agents; Isocoumarins; Magnetic Resonance Spectroscopy; Piperazines; Plant Extracts; Tryptophan | 1999 |
Amyloid beta-(1-40) stimulates cyclic GMP production via release of kinins in primary cultured endothelial cells.
Topics: Amyloid beta-Peptides; Animals; Aorta; Bradykinin; Bradykinin Receptor Antagonists; Cattle; Cells, Cultured; Coronary Vessels; Coumarins; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Isocoumarins; Kallikreins; Kinins; Microcirculation; Microscopy, Electron; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Rats; Serine Proteinase Inhibitors | 1999 |
Evaluation of the genotoxic potential of the isocoumarin paepalantine in in vivo and in vitro mammalian systems.
Topics: Adult; Animals; Anti-Infective Agents; Bone Marrow; Cells, Cultured; Chromosome Aberrations; Coumarins; Female; Humans; Isocoumarins; Lymphocytes; Male; Mutagenicity Tests; Rats; Rats, Wistar | 1999 |
Isolation and characterization of bovine thymus multicatalytic proteinase complex.
Topics: Animals; Blotting, Western; Cattle; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Electrophoresis, Gel, Two-Dimensional; Isocoumarins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Spleen; Thymus Gland | 2000 |
Synergy of amlodipine and angiotensin-converting enzyme inhibitors in regulating myocardial oxygen consumption in normal canine and failing human hearts.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Calcium Channel Blockers; Child; Coumarins; Dogs; Drug Synergism; Drug Therapy, Combination; Female; Heart Failure; Humans; Isocoumarins; Male; Middle Aged; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen Consumption; Penicillamine; Ramipril; Serine Proteinase Inhibitors | 1999 |
Proteasome from cytokine-treated human cells shows stimulated BrAAP activity and depressed PGPH activity.
Topics: Amino Acids, Branched-Chain; Cells, Cultured; Coumarins; Cysteine Endopeptidases; Endopeptidases; Endothelium, Vascular; Humans; Interferon-gamma; Interleukin-1; Interleukin-6; Isocoumarins; Lipopolysaccharides; Multienzyme Complexes; Proteasome Endopeptidase Complex; Proteins; Serine Proteinase Inhibitors; Tumor Necrosis Factor-alpha; Umbilical Veins | 2000 |
Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Binding, Competitive; Calcium; Calmodulin; Cell Line; Coumarins; Cysteine Proteinase Inhibitors; Cytosol; Dipeptides; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Endoplasmic Reticulum; Humans; Inhibitory Concentration 50; Intracellular Membranes; Isocoumarins; Ketones; Mice; Molecular Sequence Data; Plasmids; Protein Binding; Protein Biosynthesis; Protein Sorting Signals; Protein Synthesis Inhibitors; Puromycin; Serine Proteinase Inhibitors; Substrate Specificity; Time Factors; Transcription, Genetic | 2000 |
Isolated ricin B-chain-mediated apoptosis in U937 cells.
Topics: Apoptosis; Aspartic Acid; Brefeldin A; Cell Nucleus; Coumarins; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Humans; Isocoumarins; Oligopeptides; Protein Biosynthesis; Protein Synthesis Inhibitors; Ricin; Serine Proteinase Inhibitors; U937 Cells | 2000 |
Acute myeloblastic leukemic cells acquire cellular cytotoxicity under genotoxic stress: implication of granzyme B and perforin.
Topics: Antigens, CD34; Antineoplastic Agents; Cell Survival; Coumarins; Cytarabine; Cytotoxicity Tests, Immunologic; Daunorubicin; DNA, Antisense; Edetic Acid; Etoposide; Flow Cytometry; Granzymes; HeLa Cells; Humans; Isocoumarins; Jurkat Cells; K562 Cells; Leukemia, Myeloid, Acute; Magnesium Chloride; Membrane Glycoproteins; Perforin; Pore Forming Cytotoxic Proteins; Serine Endopeptidases; Tumor Cells, Cultured; U937 Cells | 2000 |
NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity.
Topics: Adenocarcinoma; Animals; Carcinoma, Lewis Lung; Cell Movement; Cells, Cultured; Collagen; Coumarins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Combinations; Endothelium, Vascular; Esophageal Neoplasms; Female; Humans; Isocoumarins; Laminin; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms; Proteoglycans; Radiation, Ionizing; Time Factors; Tumor Cells, Cultured; Umbilical Veins | 2000 |
Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis.
Topics: Animals; Apoptosis; Behavior, Animal; Brain Injuries; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Coumarins; Culture Media, Serum-Free; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Isocoumarins; Male; Motor Activity; Neurons; Nucleic Acid Synthesis Inhibitors; Potassium; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Serine Proteinase Inhibitors; Spatial Behavior; Staurosporine; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Wounds, Nonpenetrating | 2001 |
Synthesis and biological evaluation of cytogenin derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Arthritis; Coumarins; Drug Stability; In Vitro Techniques; Isocoumarins; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2001 |
Stereoselective synthesis of pseudopeptide microbial agent AI-77-B.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Coumarins; Isocoumarins; Peptides; Stereoisomerism | 2001 |
Three new dihydroisocoumarins from the Greek endemic species Scorzonera cretica.
Topics: Asteraceae; Chromatography; Circular Dichroism; Coumarins; Glycosides; Greece; Hydrolysis; Isocoumarins; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ochratoxins; Spectrophotometry, Ultraviolet | 2001 |
Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Aorta; Breast Neoplasms; Cell Movement; Coumarins; Cyclophosphamide; Drug Synergism; Endothelium, Vascular; Female; Fluorouracil; Growth Inhibitors; Humans; Isocoumarins; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2002 |
Epitope-specific antibody-induced cleavage of angiotensin-converting enzyme from the cell surface.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cell Membrane; Cells, Cultured; CHO Cells; Coumarins; Cricetinae; Endopeptidases; Endothelium, Vascular; Epitopes; Humans; Isocoumarins; Kinetics; Peptidyl-Dipeptidase A; Recombinant Proteins; Serine Proteinase Inhibitors; Transfection; Umbilical Veins | 2002 |
Dipeptidyl peptidase with strict substrate specificity of an anaerobic periodontopathogen Porphyromonas gingivalis.
Topics: Alanine; Anaerobiosis; Bacterial Proteins; Cations, Divalent; Coumarins; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isocoumarins; Isoelectric Point; Isoflurophate; Molecular Weight; Porphyromonas gingivalis; Prevotella; Prevotella intermedia; Serine Proteinase Inhibitors; Species Specificity; Substrate Specificity | 2002 |
Phyllodulcin, a constituent of "Amacha", inhibits phosphodiesterase in bovine adrenocortical cells.
Topics: Adrenal Cortex; Animals; Cattle; Cells, Cultured; Coumarins; Hydrangea; Isocoumarins; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases | 2002 |
Molecular and biochemical characterisation of two aspartic proteinases TcAP1 and TcAP2 from Theobroma cacao seeds.
Topics: Amino Acid Sequence; Aspartic Acid Endopeptidases; Cacao; Cloning, Molecular; Coumarins; DNA, Complementary; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Hydrogen-Ion Concentration; Isocoumarins; Isoenzymes; Leucine; Molecular Sequence Data; Pepstatins; Phylogeny; Plant Proteins; RNA, Messenger; Seeds; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Yarrowia | 2002 |
Typhaphthalide and typharin, two phenolic compounds from Typha capensis.
Topics: Benzofurans; Coumarins; Isocoumarins; Magnetic Resonance Spectroscopy; Molecular Structure; Phenols; Rhizome; Typhaceae | 2002 |
The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Death; Coumarins; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Down-Regulation; Female; Humans; Immunoblotting; Isocoumarins; Necrosis; Reactive Oxygen Species; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
[A study on DPPH free-radical scavengers from Xylaria nigripes].
Topics: Ascomycota; Biphenyl Compounds; Chromatography, Gel; Chromatography, High Pressure Liquid; Coumarins; Free Radical Scavengers; Isocoumarins; Picrates | 2001 |
Stilbenecarboxylate biosynthesis: a new function in the family of chalcone synthase-related proteins.
Topics: Acyltransferases; Amino Acid Sequence; Amino Acid Substitution; Benzopyrans; Chalcone; Cloning, Molecular; Coenzyme A; Coumarins; Decarboxylation; Electrophoresis, Polyacrylamide Gel; Hydrangea; Isocoumarins; Molecular Sequence Data; Recombinant Proteins; Salicylates; Sequence Homology, Amino Acid; Stilbenes; Substrate Specificity | 2003 |
Convenient total synthesis of NM-3, an antiangiogenesis agent, and its optical resolution.
Topics: Angiogenesis Inhibitors; Coumarins; Isocoumarins; Molecular Conformation | 2003 |
Structural and sensory characterization of compounds contributing to the bitter off-taste of carrots (Daucus carota L.) and carrot puree.
Topics: Alkynes; Chromatography, Gel; Chromatography, High Pressure Liquid; Cold Temperature; Coumarins; Daucus carota; Diynes; Fatty Alcohols; Food Preservation; Gallic Acid; Glucosides; Humans; Isocoumarins; Plant Extracts; Solvents; Taste | 2003 |
Effect of the isocoumarin paepalantine on the luminol and lucigenin amplified chemiluminescence of rat neutrophils.
Topics: Acridines; Animals; Antioxidants; Cell Survival; Coumarins; Hypochlorous Acid; In Vitro Techniques; Isocoumarins; Luminescent Measurements; Luminol; Male; Neutrophils; Peroxidase; Rats | 2003 |
Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Infusions, Parenteral; Injections, Intravenous; Isocoumarins; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Necrosis; Neoplasms, Experimental | 2003 |
Formal synthesis of angiogenesis inhibitor NM-3.
Topics: Angiogenesis Inhibitors; Coumarins; Indicators and Reagents; Isocoumarins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation | 2003 |
Granzyme A mediates glucocorticoid-induced apoptosis in leukemia cells.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; Coumarins; Dexamethasone; Gene Expression Profiling; Genes, bcl-2; Glucocorticoids; Granzymes; Humans; Isocoumarins; Leukemia, B-Cell; Models, Biological; RNA, Messenger; Serine Endopeptidases; Serine Proteinase Inhibitors; Transfection; Tumor Cells, Cultured | 2003 |
Studies of hydrangenol in hydrangea macrophylla Ser. I. Isolation, identification, and biosynthesis from C 14-labelled compounds.
Topics: Chemistry, Pharmaceutical; Coumarins; Germ-Free Life; Glycosides; Hydrangea; Isocoumarins; Plants; Plants, Medicinal | 1960 |
Studies of hydrangenol in Hydrangea macrophylla Ser. II. Biosynthesis of hydrangenol from C14-labelled compounds.
Topics: Coumarins; Hydrangea; Isocoumarins; Plants | 1962 |
Topoisomerase I inactivation by reticulol and its in vivo cytotoxicity against B16F10 melanoma.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Coumarins; DNA Topoisomerases, Type I; Doxorubicin; Drug Therapy, Combination; Female; Injections, Intravenous; Isocoumarins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Phosphodiesterase Inhibitors; Skin Neoplasms; Topoisomerase I Inhibitors | 2003 |
Isolation and structural elucidation of 5-formyl-2,3-dihydroisocoumarin from Centaurium erythraea aerial parts.
Topics: Centaurium; Coumarins; Isocoumarins; Plant Leaves | 2003 |
Molecule action mechanisms of NM-3 on human gastric cancer SGC-7901 cells in vivo or in vitro.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carboplatin; Cell Line, Tumor; Coumarins; Drug Synergism; Female; Humans; In Vitro Techniques; Isocoumarins; Mice; Mice, Inbred BALB C; Mice, Nude; Microcirculation; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2003 |
Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes.
Topics: Animals; Annexins; Calcium; Caspases; Cell Death; Cell Size; Ceramides; Coumarins; Erythrocytes; Fumonisins; Humans; Ionomycin; Isocoumarins; Mice; Mice, Knockout; Osmotic Pressure; Protein Binding; Sphingomyelin Phosphodiesterase; Sphingomyelins | 2004 |
Mutagenicity of paepalantine dimer and glycoside derivatives from Paepalanthus bromelioides.
Topics: Animals; Coumarins; Cricetinae; Dimerization; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eriocaulaceae; Glycosides; Isocoumarins; Methylene Chloride; Mutagenicity Tests; Mutagens; Plant Extracts; Plants, Medicinal; Salmonella typhimurium; Species Specificity; Spindle Apparatus; Structure-Activity Relationship | 2004 |
Synthesis of 6,8-dihydroxy-3-(2'-acetyl-3',5'-dihydroxyphenyl)methylisocoumarin related to feralolide.
Topics: Aloe; Coumarins; Humans; Isocoumarins; Phytotherapy; Plant Extracts; Resorcinols | 2004 |
Metabolic fate of orally administered phyllodulcin in rats.
Topics: Administration, Oral; Animals; Bacitracin; Benzopyrans; Coumarins; Feces; Hydrangea; Isocoumarins; Kanamycin; Liver; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Sulfathiazoles; Tetracycline; Urine | 2004 |
Occurrence of 6-methoxymellein in fresh and processed carrots and relevant effect of storage and processing.
Topics: Alternaria; Beverages; Coumarins; Daucus carota; Food Contamination; Food Handling; Isocoumarins | 2004 |
Three isocoumarins and a benzofuran from the cultured lichen mycobionts of Pyrenula sp.
Topics: Benzofurans; Coumarins; Isocoumarins; Lichens; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure | 2004 |
2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid, a small molecule isocoumarin, potentiates dexamethasone-induced apoptosis of human multiple myeloma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Coumarins; Cytochromes c; Dexamethasone; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Isocoumarins; Mitochondria; Mitochondrial Proteins; Multiple Myeloma; Reactive Oxygen Species | 2004 |
Absolute stereochemistry of unusual biopolymers from Ascomycete culture LL-W1278: examples that derivatives of (S)-6-hydroxymellein are also natural fungal metabolites.
Topics: Ascomycota; Biopolymers; Circular Dichroism; Coumarins; Hydrolysis; Isocoumarins; Magnetic Resonance Spectroscopy; Molecular Structure; Stereoisomerism | 2005 |
Effect of cytogenin, a novel immunomodulator, on streptozotocin-induced diabetes in mice.
Topics: Animals; Blood Glucose; Body Weight; Coumarins; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Immunologic Factors; In Vitro Techniques; Interleukin-6; Islets of Langerhans; Isocoumarins; Macrophages; Mice; Nitric Oxide | 2005 |
Two new dihydroisocoumarins from the fungus Cephalosporium sp. AL031.
Topics: Acremonium; Coumarins; Isocoumarins; Molecular Structure | 2005 |
The death receptor pathway is not involved in alloreactive T-cell induced mitochondrial membrane permeability.
Topics: Apoptosis; Caspase Inhibitors; Cell Line, Transformed; Coumarins; Cysteine Proteinase Inhibitors; Cytotoxicity Tests, Immunologic; fas Receptor; Humans; Intracellular Membranes; Isocoumarins; Macrolides; Mitochondria; Oligopeptides; Permeability; Receptors, Tumor Necrosis Factor; Signal Transduction; T-Lymphocytes, Cytotoxic | 2005 |
A formal synthesis of psymberin.
Topics: Aldehydes; Alkadienes; Catalysis; Coumarins; Epoxy Compounds; Isocoumarins; Molecular Structure; Oxidation-Reduction; Pyrans; Pyrones; Stereoisomerism | 2007 |
The effect of bafilomycin A1 and protease inhibitors on the degradation and recycling of a Class 5-mutant LDLR.
Topics: Animals; Biotinylation; CHO Cells; Coumarins; Cricetinae; Cricetulus; Enzyme Inhibitors; Humans; Immunohistochemistry; Isocoumarins; Macrolides; Mutation; Plasmids; Protease Inhibitors; Receptors, LDL; Sulfones; Transfection | 2009 |
Two new cleistanthane diterpenes and a new isocoumarine from cultures of the basidiomycete Albatrellus confluens.
Topics: Basidiomycota; Coumarins; Diterpenes; Isocoumarins; Magnetic Resonance Spectroscopy | 2009 |
Reticulone, a novel free radical scavenger produced by Aspergillus sp.
Topics: Aspergillus; Benzaldehydes; Benzothiazoles; Biphenyl Compounds; Butylated Hydroxyanisole; Caffeic Acids; Coumarins; Free Radical Scavengers; Industrial Microbiology; Isocoumarins; Magnetic Resonance Spectroscopy; Oxidative Stress; Picrates; Sulfonic Acids | 2009 |
Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; Chromones; Coumarins; DNA-Activated Protein Kinase; Humans; Inhibitory Concentration 50; Isocoumarins; Structure-Activity Relationship | 2010 |
Total synthesis and cytotoxic activity of stellatin.
Topics: Aspergillus; Coumarins; Cytotoxins; Dose-Response Relationship, Drug; Emericella; Humans; Isocoumarins; Keratinocytes; Molecular Structure | 2011 |
Synthesis, biological evaluation and molecular docking studies of stellatin derivatives as cyclooxygenase (COX-1, COX-2) inhibitors and anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Catalytic Domain; Coumarins; Cyclooxygenase Inhibitors; Isocoumarins; Mice; Models, Molecular | 2011 |
Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6.
Topics: Activating Transcription Factor 6; Animals; Antineoplastic Agents; Apoptosis; Caspase 6; Caspase 9; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Coumarins; Endoplasmic Reticulum; Enzyme Activation; Fatty Acid Synthase, Type I; Female; Humans; Isocoumarins; Liposarcoma; Metalloendopeptidases; Mice; Mice, SCID; Nelfinavir; Neoplasm Transplantation; Phenanthrolines; Proprotein Convertases; Protease Inhibitors; Protein Transport; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Serine Endopeptidases; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Transplantation, Heterologous; Tumor Burden | 2011 |
Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing.
Topics: Animals; Antibodies, Blocking; Cell Line; Coumarins; Culture Media, Conditioned; Endopeptidases; Humans; Isocoumarins; Keratinocytes; Mice; Mice, Inbred C57BL; Recombinant Proteins; RNA, Small Interfering; Serine Endopeptidases; Serine Proteases; Serine Proteinase Inhibitors; Skin; Thrombomodulin; Wound Healing | 2011 |
Crystallization and preliminary X-ray diffraction studies of a complex of extracellular lipase from Streptomyces rimosus with the inhibitor 3,4-dichloroisocoumarin.
Topics: Coumarins; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Extracellular Space; Isocoumarins; Lipase; Streptomyces | 2011 |
Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate.
Topics: Bacterial Proteins; Coumarins; Crystallography, X-Ray; Isocoumarins; Isoflurophate; Models, Molecular; Peptide Hydrolases; Protease Inhibitors; Protein Structure, Secondary; Protein Structure, Tertiary; Providencia | 2012 |
Granzyme B cleaves decorin, biglycan and soluble betaglycan, releasing active transforming growth factor-β1.
Topics: Biglycan; Biocatalysis; Blotting, Western; Cells, Cultured; Coumarins; Decorin; Extracellular Matrix; Extracellular Space; Granzymes; Humans; Isocoumarins; Kinetics; Muscle, Smooth, Vascular; Phosphorylation; Proteoglycans; Receptors, Transforming Growth Factor beta; Serine Proteinase Inhibitors; Smad3 Protein; Solubility; Substrate Specificity; Transforming Growth Factor beta1 | 2012 |
Granule exocytosis mediates immune surveillance of senescent cells.
Topics: Animals; Apoptosis; beta-Galactosidase; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; Cellular Senescence; Coumarins; Cytoplasmic Granules; Enzyme Inhibitors; Exocytosis; Extracellular Matrix Proteins; Hepatic Stellate Cells; Humans; Immunologic Surveillance; Isocoumarins; Killer Cells, Natural; Liver; Liver Cirrhosis; Macrolides; Mice; Mice, Inbred C57BL; Mice, Knockout; Perforin; RNA Interference; RNA, Small Interfering; Serine Proteinase Inhibitors; Tumor Necrosis Factor Decoy Receptors | 2013 |
Inhibition of extracellular lipase from Streptomyces rimosus with 3,4-dichloroisocoumarin.
Topics: Coumarins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Isocoumarins; Lipase; Molecular Structure; Streptomyces; Structure-Activity Relationship | 2013 |
Isolation, identification and antimicrobial activities of two secondary metabolites of Talaromyces verruculosus.
Topics: Acrylates; Anti-Infective Agents; Bacteria; Coumarins; Fungi; Isocoumarins; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Pyrrolidines; Talaromyces | 2012 |
[Chemical constituents of the fruits of Lycium ruthenicum].
Topics: Anthocyanins; Chromatography, High Pressure Liquid; Coumaric Acids; Coumarins; Dextrans; Drugs, Chinese Herbal; Fruit; Isocoumarins; Lycium; Quercetin | 2012 |
Malingering and factitious disorders and illnesses, active component, U.S. Armed Forces, 1998-2012.
Topics: Adult; Afghan Campaign 2001-; Coumarins; Factitious Disorders; Female; Humans; Iraq War, 2003-2011; Isocoumarins; Male; Malingering; Military Personnel; Population Surveillance; Young Adult | 2013 |
Molecular biology. A splicing magic bullet.
Topics: Alternative Splicing; Animals; Coumarins; Humans; Isocoumarins; Longevity; Muscular Atrophy, Spinal; Pyrimidinones; Small Molecule Libraries; Survival of Motor Neuron 2 Protein | 2014 |
Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.
Topics: Administration, Oral; Alternative Splicing; Animals; Cells, Cultured; Coumarins; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Isocoumarins; Longevity; Mice; Muscular Atrophy, Spinal; Pyrimidinones; RNA, Messenger; Sequence Deletion; Small Molecule Libraries; Survival of Motor Neuron 2 Protein | 2014 |
Neuromuscular disorders: Beefing up the right splice variant to treat spinal muscular atrophy.
Topics: Alternative Splicing; Animals; Coumarins; Humans; Isocoumarins; Longevity; Muscular Atrophy, Spinal; Pyrimidinones; Small Molecule Libraries; Survival of Motor Neuron 2 Protein | 2014 |
Botryoisocoumarin A, a new COX-2 inhibitor from the mangrove Kandelia candel endophytic fungus Botryosphaeria sp. KcF6.
Topics: Antibiotics, Antineoplastic; Ascomycota; Cell Line, Tumor; Coumarins; Cyclooxygenase 2 Inhibitors; Fermentation; Fruit; Humans; Isocoumarins; Magnetic Resonance Spectroscopy; Rhizophoraceae; X-Ray Diffraction | 2015 |
Inhibitor Fingerprinting of Rhomboid Proteases by Activity-Based Protein Profiling Reveals Inhibitor Selectivity and Rhomboid Autoprocessing.
Topics: Bacterial Proteins; Coumarins; Escherichia coli Proteins; Inhibitory Concentration 50; Isocoumarins; Models, Biological; Models, Molecular; Protease Inhibitors; Protein Array Analysis; Small Molecule Libraries; Substrate Specificity | 2015 |
New isocoumarin and stilbenoid derivatives from the tubers of Sparganium stoloniferum (Buch.-Ham.).
Topics: Benzofurans; Coumarins; Drugs, Chinese Herbal; Isocoumarins; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Plant Tubers; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stilbenes; Typhaceae | 2017 |
A metal-free one-pot synthesis of benzo[c]chromen-6-ones from 3,4-dichlorocoumarins and butadienes using tandem photo-thermal-photo reactions.
Topics: Benzopyrans; Butadienes; Chemistry Techniques, Synthetic; Coumarins; Isocoumarins; Photochemical Processes; Temperature | 2016 |
Organocatalytic Asymmetric Benzylation and Aldol-Hemiacetalization of α,β-Unsaturated Trifluoromethyl Ketones: Efficient Enantioselective Construction of 3,4-Dihydroisocoumarins.
Topics: Aldehydes; Amines; Carbon; Catalysis; Coumarins; Crystallography, X-Ray; Isocoumarins; Ketones; Molecular Conformation; Stereoisomerism; Thiourea; Toluene | 2017 |
Activation of a Silent Polyketide Synthase SlPKS4 Encoding the C
Topics: Coumarins; Hypocreales; Isocoumarins; Polyketide Synthases | 2023 |