isocoumarins has been researched along with galloflavin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (88.24) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Buonfiglio, R; Di Stefano, G; Fiume, L; Giacomini, E; Manerba, M; Recanatini, M; Roberti, M; Sartini, A; Vettraino, M | 1 |
| Di Stefano, G; Farabegoli, F; Fiume, L; Manerba, M; Roberti, M; Vettraino, M | 1 |
| Arfilli, V; Brigotti, M; Carnicelli, D; Di Stefano, G; Fiume, L; Vettraino, M | 1 |
| Di Stefano, G; Govoni, M; Manerba, M; Vettraino, M | 1 |
| Bae-Jump, VL; Han, X; Jackson, AL; Jones, HM; Kilgore, J; Schointuch, MN; Sheng, X; Stine, JE; Zhou, C | 1 |
| An, YJ; Kang, KW; Park, S; Wen, H; Xu, WJ | 1 |
| Di Ianni, L; Di Stefano, G; Fiume, L; Manerba, M; Recanatini, M; Roberti, M | 1 |
| Jin, H; Lian, N; Lu, Y; Shao, J; Wu, L; Zhang, F; Zheng, S | 1 |
| Di Ianni, L; Di Stefano, G; Govoni, M; Manerba, M; Recanatini, M; Roberti, M | 2 |
| Di Ianni, L; Di Stefano, G; Falchi, F; Giacomini, E; Guidotti, L; Manerba, M; Recanatini, M; Roberti, M; Rupiani, S | 1 |
| Barreca, D; Bellocco, E; Calderaro, A; Laganá, G | 1 |
| Abdel-Gawad, SA; Alafeefy, AM; Alasmary, FAS; Altamimi, AS; Balode, A; El Shikh, ME; Pustenko, A; Vozny, I; Žalubovskis, R | 1 |
| Brunetti-Pierri, N; Carissimo, A; De Cegli, R; Ferriero, R; Manco, G; Nusco, E | 1 |
| Gandrillon, O; Gonin-Giraud, S; Richard, A; Romestaing, C; Roussel, D; Vallin, E | 1 |
| Schoenrogge, M; Vollmar, B; Wendt, EHU; Zechner, D | 1 |
| Huovinen, M; Ihantola, EL; Järvenpää, J; Khadeer, M; Küblbeck, J; Lahtela-Kakkonen, M; Moaddel, R; Rahnasto-Rilla, M; Schroderus, AM | 1 |
1 review(s) available for isocoumarins and galloflavin
| Article | Year |
|---|---|
Lactate Dehydrogenase Inhibition: Biochemical Relevance and Therapeutical Potential.
Topics: Animals; Antimalarials; Azoles; Drug Discovery; Enzyme Inhibitors; Gossypol; Humans; Indoles; Isocoumarins; L-Lactate Dehydrogenase; Organic Chemicals; Plasmodium falciparum; Quinolines | 2019 |
16 other study(ies) available for isocoumarins and galloflavin
| Article | Year |
|---|---|
Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.
Topics: Apoptosis; Binding Sites; Cell Line; Computer Simulation; Enzyme Activation; Enzyme Inhibitors; Glycolysis; Humans; Hydrogen Bonding; Isocoumarins; Kinetics; L-Lactate Dehydrogenase; Protein Isoforms; Protein Structure, Tertiary | 2012 |
Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways.
Topics: Apoptosis; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Energy Metabolism; Female; Glucose; Glycolysis; Humans; Isocoumarins; L-Lactate Dehydrogenase; Lymphocytes; MCF-7 Cells; Oxidative Stress; Oxygen Consumption; Signal Transduction | 2012 |
Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells.
Topics: Cell Line, Tumor; DNA, Single-Stranded; Humans; Isocoumarins; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Protein Binding; RNA | 2013 |
Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.
Topics: Adenosine Triphosphate; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Inhibitory Concentration 50; Isocoumarins; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; NAD; Proto-Oncogene Proteins c-myc; Signal Transduction; Sirtuin 1; Time Factors | 2013 |
Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Enzyme Inhibitors; Female; Glycolysis; Humans; Isocoumarins; L-Lactate Dehydrogenase | 2015 |
Real-time monitoring of cancer cell metabolism and effects of an anticancer agent using 2D in-cell NMR spectroscopy.
Topics: Acetates; Alanine; Antineoplastic Agents; Hep G2 Cells; Hepatocytes; Humans; Isocoumarins; L-Lactate Dehydrogenase; Metabolome; Nuclear Magnetic Resonance, Biomolecular; Pyruvic Acid | 2015 |
Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes.
Topics: Antineoplastic Agents; Burkitt Lymphoma; Cell Line, Transformed; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glycolysis; Humans; Isocoumarins; L-Lactate Dehydrogenase; Lymphocytes; Neoplasm Proteins; Organic Chemicals; Osmolar Concentration; Reactive Oxygen Species | 2015 |
Curcumin inhibits aerobic glycolysis in hepatic stellate cells associated with activation of adenosine monophosphate-activated protein kinase.
Topics: Actins; AMP-Activated Protein Kinases; Animals; Collagen Type I; Collagen Type I, alpha 1 Chain; Curcumin; Deoxyglucose; Extracellular Matrix; Gene Expression Regulation; Glucose Transporter Type 4; Glycolysis; Hepatic Stellate Cells; Hexokinase; Humans; Isocoumarins; Liver; Liver Cirrhosis; Phosphofructokinase-2; Rats; Rats, Sprague-Dawley | 2016 |
Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells.
Topics: Caco-2 Cells; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Humans; Inflammation; Interleukin-17; Isocoumarins; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Oxamic Acid; RNA, Messenger; Tumor Necrosis Factor-alpha | 2017 |
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A.
Topics: Cell Line; Cell Proliferation; Chemistry Techniques, Synthetic; Enzyme Inhibitors; Humans; Isocoumarins; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid | 2016 |
LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells.
Topics: Adenosine Triphosphatases; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cellular Senescence; Heat-Shock Proteins; Heat-Shock Response; Humans; Isocoumarins; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Liver Neoplasms; Organic Chemicals; Thiobarbituric Acid Reactive Substances | 2017 |
Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isocoumarins; L-Lactate Dehydrogenase; Molecular Structure; Structure-Activity Relationship; Triazoles | 2018 |
Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure.
Topics: Animals; Cell Line; Cell Survival; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Profiling; Isocoumarins; L-Lactate Dehydrogenase; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Pyruvate Dehydrogenase Complex | 2018 |
Erythroid differentiation displays a peak of energy consumption concomitant with glycolytic metabolism rearrangements.
Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cell Line; Chickens; Energy Metabolism; Erythroid Cells; Glycolysis; Isocoumarins; Lactate Dehydrogenase 5; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Phosphorylation | 2019 |
Galloflavin Plus Metformin Treatment Impairs Pancreatic Cancer Cells.
Topics: Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Hypoglycemic Agents; Isocoumarins; Lactic Acid; Metformin; Pancreatic Neoplasms | 2020 |
Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activities.
Topics: Acetylation; Antineoplastic Agents; Caco-2 Cells; Ellagic Acid; Glucose; Glucose Transporter Type 1; Humans; Isocoumarins; Molecular Docking Simulation; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Sirtuins | 2020 |