Page last updated: 2024-08-24

isocoumarins and cladosporin

isocoumarins has been researched along with cladosporin in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's2 (8.33)18.2507
2000's0 (0.00)29.6817
2010's17 (70.83)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Anke, H; Zähner, H1
Cutler, HG; Harwood, JS; Jacyno, JM; Lee, MK1
Fujimaki, T; Fujimoto, H; Okuyama, E; Yamazaki, M1
Gilyan, A; Miller, JD; Rand, TG; Roy, J; Sun, M1
Dipenta, J; Miller, JD; Rand, TG; Robbins, C1
Fang, B; Jing, P; She, X; Xie, X; Yang, J; Zhao, C; Zheng, H1
Aust, T; Bodenreider, C; Cotesta, S; Diagana, TT; Fishman, MC; Glynne, RJ; Hartmann, N; Hoepfner, D; Lim, CS; McCormack, SL; McNamara, CW; Meister, S; Movva, NR; Petersen, F; Plikat, U; Plouffe, DM; Porter, JA; Riedl, R; Schmitt, EK; Schuierer, S; Staedtler, F; Studer, C; Supek, F; Tallarico, JA; Winzeler, EA1
Cutler, HG; Cutler, SJ; Gao, J; Radwan, MM; Rosa, LH; Taráwneh, AH; Wang, X; Wedge, DE1
Belrhali, H; Khan, S; Sharma, A; Yogavel, M1
Deng, X; Guo, K; Kong, XJ; Li, XY; Tang, Q; Xu, QY; Zheng, XY; Zheng, ZH1
Chen, J; Ding, L; Dong, J; Gu, B; He, S; Wu, B; Yan, X; Zhang, J; Zhang, Y; Zhu, P1
Chen, K; Chen, X; Fang, P; Guo, M; Han, H; Wang, J1
Cochrane, RV; Lambkin, GR; Reiz, B; Sanichar, R; Tang, Y; Vederas, JC; Xu, W1
Aldemir, H; Gulder, TAM; Imhoff, JF; Schmaljohann, R; Wiese, J1
Babbar, P; Das, P; Gonnade, RG; Harlos, K; Jachak, GR; Malhotra, N; Reddy, DS; Shanmugam, D; Sharma, A; Sharma, M; Yogavel, M1
Fredenhagen, A; Freund, E; Hoepfner, D; Ligibel, M; Meishammer, A; Porchet Zemp, L; Radoch, C; Schröder, H; Schroer, K1
Aust, T; Bouchez, LC; Gademann, K; Hoepfner, D; Livendahl, M; Patoor, M; Ranieri, B; Rollin, P; Rusch, M; Schmitt, E; Spanka, C; Studer, C; Thevenon, A1
Cutler, SJ; Wang, X; Wedge, DE1
Chhibber-Goel, J; Sharma, A1
Chhibber-Goel, J; Joshi, S; Sharma, A1
Fang, P; Hei, Z; Li, W; Wang, J; Yu, B; Zheng, L; Zhou, J1
Das, P; Deshpande, MV; Mankad, Y; Pathan, E; Reddy, DS1
Babbar, P; Das, P; Manickam, Y; Mankad, Y; Parvez, S; Reddy, DS; Sharma, A; Yadav, S1
Deng, Z; Dickschat, JS; Hou, A; Li, B; Xu, M1

Reviews

2 review(s) available for isocoumarins and cladosporin

ArticleYear
Chemical and Biological Study of Cladosporin, an Antimicrobial Inhibitor: A Review.
    Natural product communications, 2016, Volume: 11, Issue:10

    Topics: Animals; Antifungal Agents; Cladosporium; Herbicides; Humans; Isocoumarins

2016
Cladosporin, A Highly Potent Antimalaria Drug?
    Chembiochem : a European journal of chemical biology, 2023, 06-15, Volume: 24, Issue:12

    Topics: Antimalarials; Humans; Isocoumarins; Lysine-tRNA Ligase; Malaria; Malaria, Falciparum; Plasmodium falciparum

2023

Other Studies

22 other study(ies) available for isocoumarins and cladosporin

ArticleYear
Metabolic products of microorganisms. 170. On the antibiotic activity of cladosporin.
    Archives of microbiology, 1978, Volume: 116, Issue:3

    Topics: Antifungal Agents; Ascomycota; Bacteria; Chemical Phenomena; Chemistry; Coumarins; Fermentation; Fungi; Isocoumarins; Methylation; Pyrans; Species Specificity; Spores, Fungal

1978
Isocladosporin, a biologically active isomer of cladosporin from Cladosporium cladosporioides.
    Journal of natural products, 1993, Volume: 56, Issue:8

    Topics: Cladosporium; Coumarins; Isocoumarins; Mass Spectrometry; Molecular Conformation; Mycotoxins; Spectrophotometry, Ultraviolet; Stereoisomerism; Triticum

1993
Immunomodulatory constituents from an ascomycete, Microascus tardifaciens.
    Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:10

    Topics: Anthracenes; Anthraquinones; Ascomycota; Coumarins; Drugs, Chinese Herbal; Emodin; Immunosuppressive Agents; Isocoumarins; Magnetic Resonance Spectroscopy; Piperazines; Plant Extracts; Tryptophan

1999
Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment.
    Chemico-biological interactions, 2010, Jan-05, Volume: 183, Issue:1

    Topics: Air Pollution, Indoor; Alkaloids; Animals; Benzofurans; Chemokine CXCL2; Cluster Analysis; Fungi; Gene Expression Profiling; Inflammation Mediators; Isocoumarins; Isoquinolines; Lung; Macrophages, Alveolar; Male; Mice; Mycophenolic Acid; Mycotoxins; Piperazines; Sterigmatocystin; Transcription, Genetic; Tumor Necrosis Factor-alpha

2010
Effects of low molecular weight fungal compounds on inflammatory gene transcription and expression in mouse alveolar macrophages.
    Chemico-biological interactions, 2011, Apr-25, Volume: 190, Issue:2-3

    Topics: Alkaloids; Animals; Benzofurans; beta-Glucans; Cells, Cultured; Cluster Analysis; Cytokines; Fungi; Gene Expression Regulation; Indole Alkaloids; Inflammation Mediators; Isocoumarins; Isoquinolines; Lipopolysaccharides; Macrophages, Alveolar; Male; Mice; Molecular Weight; Piperazines; Spiro Compounds; Sterigmatocystin; Transcription, Genetic

2011
Asymmetric total synthesis of cladosporin and isocladosporin.
    The Journal of organic chemistry, 2012, Jul-06, Volume: 77, Issue:13

    Topics: Isocoumarins; Molecular Structure; Stereoisomerism

2012
Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
    Cell host & microbe, 2012, Jun-14, Volume: 11, Issue:6

    Topics: Antimalarials; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fungi; Humans; Inhibitory Concentration 50; Isocoumarins; Lysine-tRNA Ligase; Parasitic Sensitivity Tests; Plasmodium falciparum; Protein Biosynthesis; Protozoan Proteins

2012
Antifungal activity against plant pathogens of metabolites from the endophytic fungus Cladosporium cladosporioides.
    Journal of agricultural and food chemistry, 2013, May-15, Volume: 61, Issue:19

    Topics: Ascomycota; Cladosporium; Colletotrichum; Fungicides, Industrial; Isocoumarins; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Plant Diseases

2013
Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin.
    Journal of structural and functional genomics, 2014, Volume: 15, Issue:2

    Topics: Animals; Antimalarials; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Isocoumarins; Lysine-tRNA Ligase; Plasmodium falciparum; Protein Conformation

2014
Three new asperentin derivatives from the algicolous fungus Aspergillus sp. F00785.
    Marine drugs, 2014, Dec-15, Volume: 12, Issue:12

    Topics: Anti-Bacterial Agents; Aspergillus; Colletotrichum; Crystallography, X-Ray; Fungi; Isocoumarins; Magnetic Resonance Spectroscopy; Marine Biology; Stramenopiles

2014
Preparative separation of sulfur-containing diketopiperazines from marine fungus Cladosporium sp. using high-speed counter-current chromatography in stepwise elution mode.
    Marine drugs, 2015, Jan-09, Volume: 13, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cladosporium; Countercurrent Distribution; Diketopiperazines; Indoles; Isocoumarins; Molecular Structure; Piperazines

2015
Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor.
    Chemistry & biology, 2015, Jun-18, Volume: 22, Issue:6

    Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Binding Sites; Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; Humans; Isocoumarins; Molecular Dynamics Simulation; Plasmodium falciparum; Protozoan Proteins; Recombinant Proteins

2015
Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent.
    Angewandte Chemie (International ed. in English), 2016, Jan-11, Volume: 55, Issue:2

    Topics: Antimalarials; Isocoumarins; Polyketide Synthases

2016
Asperentin B, a New Inhibitor of the Protein Tyrosine Phosphatase 1B.
    Marine drugs, 2017, Jun-21, Volume: 15, Issue:6

    Topics: Aspergillus; Cell Line, Tumor; Diabetes Mellitus, Type 2; Enzyme Inhibitors; HT29 Cells; Humans; Insulin; Isocoumarins; Mediterranean Sea; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Signal Transduction

2017
Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite.
    Journal of medicinal chemistry, 2018, 07-12, Volume: 61, Issue:13

    Topics: Antimalarials; Drug Evaluation, Preclinical; Isocoumarins; Lysine-tRNA Ligase; Models, Molecular; Plasmodium falciparum; Protein Conformation; Stereoisomerism

2018
Cladosporin Derivatives Obtained by Biotransformation Provide Guidance for the Focused Derivatization of this Antimalarial Lead Compound.
    Chembiochem : a European journal of chemical biology, 2019, 03-01, Volume: 20, Issue:5

    Topics: Antimalarials; Bacteria; Biotransformation; Drug Discovery; Enzyme Inhibitors; Fungi; Isocoumarins; Lysine-tRNA Ligase; Malaria, Falciparum; Plasmodium falciparum; Structure-Activity Relationship

2019
Design and Synthesis of Metabolically Stable tRNA Synthetase Inhibitors Derived from Cladosporin.
    Chembiochem : a European journal of chemical biology, 2019, 03-01, Volume: 20, Issue:5

    Topics: Antimalarials; Drug Discovery; Enzyme Inhibitors; Humans; Isocoumarins; Lysine-tRNA Ligase; Malaria, Falciparum; Plasmodium falciparum; Structure-Activity Relationship

2019
Side chain rotameric changes and backbone dynamics enable specific cladosporin binding in Plasmodium falciparum lysyl-tRNA synthetase.
    Proteins, 2019, Volume: 87, Issue:9

    Topics: Cryptosporidium parvum; Isocoumarins; Lysine-tRNA Ligase; Mycobacterium ulcerans; Plasmodium falciparum; Protein Binding

2019
Aminoacyl tRNA synthetases as potential drug targets of the Panthera pathogen Babesia.
    Parasites & vectors, 2019, Oct-14, Volume: 12, Issue:1

    Topics: Amino Acyl-tRNA Synthetases; Animals; Babesia; Babesiosis; Catalytic Domain; Computational Biology; Drug Delivery Systems; Endangered Species; Enzyme Inhibitors; Genome, Protozoan; Isocoumarins; Markov Chains; Molecular Sequence Annotation; Open Reading Frames; Panthera; Sequence Alignment

2019
Atomic Resolution Analyses of Isocoumarin Derivatives for Inhibition of Lysyl-tRNA Synthetase.
    ACS chemical biology, 2020, 04-17, Volume: 15, Issue:4

    Topics: Antimalarials; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Isocoumarins; Lysine-tRNA Ligase; Plasmodium falciparum; Protein Binding

2020
Herbicidal bio-assay of isocladosporin enantiomers and determination of its plausible absolute configuration.
    The Journal of antibiotics, 2021, Volume: 74, Issue:4

    Topics: Animals; Cladosporium; Coleoptera; Herbicides; Isocoumarins; Stereoisomerism; Structure-Activity Relationship; Triticum

2021
Design, Synthesis, and Structural Analysis of Cladosporin-Based Inhibitors of Malaria Parasites.
    ACS infectious diseases, 2021, 06-11, Volume: 7, Issue:6

    Topics: Animals; Isocoumarins; Malaria; Parasites; Plasmodium falciparum

2021