isocoumarin-nm-3 and cytogenin

isocoumarin-nm-3 has been researched along with cytogenin* in 3 studies

Other Studies

3 other study(ies) available for isocoumarin-nm-3 and cytogenin

ArticleYear
Convenient total synthesis of NM-3, an antiangiogenesis agent, and its optical resolution.
    The Journal of antibiotics, 2003, Volume: 56, Issue:1

    Topics: Angiogenesis Inhibitors; Coumarins; Isocoumarins; Molecular Conformation

2003
Synthesis and biological evaluation of cytogenin derivatives.
    The Journal of antibiotics, 2001, Volume: 54, Issue:3

    To enhance the stability in vivo, new derivatives of cytogenin were synthesized, and their biological activity and stability in mice were estimated. 2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid (NM-3) was found to be the most stable among them. It modified collagen-induced arthritis in mice. It also showed potent anti-angiogenic activity in a mouse dorsal air sac assay.

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Arthritis; Coumarins; Drug Stability; In Vitro Techniques; Isocoumarins; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared

2001
Inhibition of angiogenesis by a new isocoumarin, NM-3.
    The Journal of antibiotics, 1999, Volume: 52, Issue:4

    Topics: Animals; Anticoagulants; Antineoplastic Agents; Coumarins; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Female; Isocoumarins; Mice; Mice, Inbred ICR; Neovascularization, Pathologic; Sarcoma 180; Tumor Cells, Cultured

1999