isocoumarin-nm-3 has been researched along with cytogenin* in 3 studies
3 other study(ies) available for isocoumarin-nm-3 and cytogenin
Article | Year |
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Convenient total synthesis of NM-3, an antiangiogenesis agent, and its optical resolution.
Topics: Angiogenesis Inhibitors; Coumarins; Isocoumarins; Molecular Conformation | 2003 |
Synthesis and biological evaluation of cytogenin derivatives.
To enhance the stability in vivo, new derivatives of cytogenin were synthesized, and their biological activity and stability in mice were estimated. 2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid (NM-3) was found to be the most stable among them. It modified collagen-induced arthritis in mice. It also showed potent anti-angiogenic activity in a mouse dorsal air sac assay. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Arthritis; Coumarins; Drug Stability; In Vitro Techniques; Isocoumarins; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2001 |
Inhibition of angiogenesis by a new isocoumarin, NM-3.
Topics: Animals; Anticoagulants; Antineoplastic Agents; Coumarins; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Female; Isocoumarins; Mice; Mice, Inbred ICR; Neovascularization, Pathologic; Sarcoma 180; Tumor Cells, Cultured | 1999 |