isocitric acid and nadp

isocitric acid has been researched along with nadp in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (25.00)	18.7374
1990's	15 (28.85)	18.2507
2000's	10 (19.23)	29.6817
2010's	8 (15.38)	24.3611
2020's	6 (11.54)	2.80

Authors

Authors	Studies
Jefcoate, CR; McNamara, BC	2
Jennings, GT; Sadleir, JW; Stevenson, PM	1
Hollis, BW	1
Eguchi, H; Oshima, T; Wakagi, T	1
Colman, RF; Saha, A	1
Colman, RF; Ehrlich, RS	1
Kurkijärvi, K; Lövgren, TN; Raunio, RP	1
Jackim, E; Lindblad, WJ	1
Gabriel, JL; Plaut, GW	1
Hirschberg, JG; Kohen, C; Kohen, E; Thorell, B; Wouters, AW	1
Arisue, K; Fujita, T; Kawakami, Y; Kohda, S; Sunahara, Y; Takata, S	1
Jefcoate, CR; Kowluru, R; McNamara, BC; Yamazaki, T	1
Bolduc, JM; Dyer, DH; Koshland, DE; Scott, WG; Singer, P; Stoddard, BL; Sweet, RM	1
Colman, RF; Haselbeck, RJ; Huang, YC; McAlister-Henn, L	1
Fitton, V; Guérin, B; Ouhabi, R; Rigoulet, M	1
Kavanagh, JP	1
Farrell, HM; Kumosinski, TF; Seery, VL; Wickham, ED	1
Jefcoate, CR; McNamara, BC; Yamazaki, T	1
Dean, A; Koshland, DE; Stoddard, BL	1
Dean, AM; Koshland, DE; Shiau, AK	1
Pinheiro de Carvalho, MA; Popova, TN	1
Packard, TT; Roy, SO	1
Colman, RF; Huang, YC	2
Alvarado, A; Flores, ME	1
HAWTREY, AO; SILK, MH	1
VIGNAIS, PM; VIGNAIS, PV	1
BAKER, WW; NEWBURGH, RW	1
COSTELLO, LC; DARAGO, LL	1
HENLEY, KS; LAUGHREY, EG	1
Arnold, E; Ding, J; Huang, Q; Peng, B; Xu, X; Xu, Z; Zhao, J	1
Murakami, K; Yoshino, M	1
Contreras-Shannon, V; Lin, AP; McAlister-Henn, L; McCammon, MT	1
Garnsworthy, PC; Lock, AL; Masson, LL; Mottram, TT	1
Ishii, N; Mori, H; Murakami, K; Ogawa, T; Tomita, M; Yoshin, M	1
Ding, J; Huang, W; Peng, Y; Zhong, C	1
Berson, EL; Colman, RF; Dange, M; Dryja, TP; Hartong, DT; McGee, TL	1
Cao, Z; Song, P; Wang, P; Wei, H; Zhu, G	1
Cao, ZY; Song, P; Tang, WG; Wang, P; Zhu, GP	1
Brosnan, MJ; Colmers, WF; Dai, X; Ferdaoussi, M; Gloyn, AL; Hajmrle, C; Huang, C; Ilkayeva, O; Jensen, MV; Kibbey, RG; MacDonald, PE; Mackay, JP; Manning Fox, JE; Miller, N; Neufer, PD; Newgard, CB; Norquay, LD; Peterson, BS; Plummer, G; Rolph, TP; Ryan, TE; Shirihai, OS; Smith, N; Spigelman, AF; Suzuki, K; Trimmer, JK; van de Bunt, M; Wang, R; Wright, RC; Yeh, ET	1
Adams, ND; DeBerardinis, RJ; Dranka, BP; Jiang, L; McCabe, MT; Metallo, CM; Parker, SJ; Pietrak, B; Schmidt, S; Schwartz, B; Shestov, AA; Swain, P; Terada, LS; Wang, QA; Yang, C	1
Hendriks, WJ; Leenders, WP; Lenting, K; Molenaar, RJ; Navis, AC; Pusch, S; Schepens, JT; Schubert, NA; Tops, B; van Lith, SA; van Noorden, CJ; van Rooij, A; Venselaar, H; Verrijp, K; Wesseling, P; Wevers, RA	1
Allmann, S; Balogun, EO; Boshart, M; Harada, S; Inaoka, DK; Kita, K; Shiba, T; Wang, X; Watanabe, YI	1
Chung, J; Kang, KS; Kim, EY; Kim, H; Kim, MJ; Koh, H; Lee, Y; Min, B; Park, HT; Son, JH; Yang, J; Yoon, W	1
Ekelöf, M; Elsen, NL; Khodjaniyazova, S; Muddiman, DC; Nazari, M; Williams, JD	1
Anderson, SE; Fahey, NS; Mirkin, CA; Mrksich, M; O'Kane, PT; Park, J	1
Dvořák, A; Gotvaldová, K; Holendová, B; Hubálek, M; Ježek, P; Křenková, A; Smolková, K; Špačková, J; Vítek, L	1
Cardinali, V; Cerchione, C; Falini, B; Martelli, MP; Martinelli, G; Martino, G	1
MacLean, IA; Storey, KB; Varma, A	1
Albekioni, E; Avellaneda Matteo, D; Caliger, D; Coleman, NJ; Komives, EA; Sabo, KA; Silletti, S; Sohl, CD; Thornberg, E	1
Mattice, AMS; Storey, KB; Varma, A	1

Reviews

2 review(s) available for isocitric acid and nadp

Article	Year
Citrate and isocitrate in plant metabolism. Biochimica et biophysica acta, 1998, May-27, Volume: 1364, Issue:3 Topics: Citric Acid; Electron Transport; Isocitrates; NADP; Plants	1998
Enasidenib and ivosidenib in AML. Minerva medica, 2020, Volume: 111, Issue:5 Topics: Aminopyridines; Antineoplastic Agents; Cell Differentiation; Clinical Trials as Topic; Glutarates; Glycine; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Mutation, Missense; NADP; Pyridines; Syndrome; Triazines	2020

Other Studies

50 other study(ies) available for isocitric acid and nadp

Article	Year
Heterogeneous pools of cholesterol side-chain cleavage activity in adrenal mitochondria from ACTH-treated rats: differential responses to different reducing precursors. Molecular and cellular endocrinology, 1990, Oct-22, Volume: 73, Issue:2-3 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calcium; Caprylates; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Edetic Acid; Guanosine Triphosphate; Hydroxycholesterols; Isocitrates; Kinetics; Mitochondria; NADP; Pregnenolone; Rats; Serum Albumin, Bovine; Succinates; Succinic Acid	1990
Purification and properties of NADP(+)-dependent isocitrate dehydrogenase from the corpus luteum. Biochimica et biophysica acta, 1990, May-16, Volume: 1034, Issue:2 Topics: Animals; Blotting, Western; Cations, Divalent; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Chromatography, High Pressure Liquid; Corpus Luteum; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Female; Glycerol; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Magnesium Chloride; Molecular Weight; NADP; Protein Denaturation; Swine	1990
25-Hydroxyvitamin D3-1 alpha-hydroxylase in porcine hepatic tissue: subcellular localization to both mitochondria and microsomes. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:16 Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Cell Fractionation; Isocitrates; Ketoconazole; Kinetics; Male; Microsomes, Liver; Mitochondria, Liver; NADP; Oxidation-Reduction; Steroid Hydroxylases; Swine; Ultracentrifugation	1990
Synergistic stimulation of pregnenolone synthesis in rat adrenal mitochondria by n-hexane and cardiolipin. Archives of biochemistry and biophysics, 1988, Feb-01, Volume: 260, Issue:2 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Cardiolipins; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Drug Synergism; Female; Hexanes; Isocitrates; Kinetics; Mitochondria; NADP; Pregnenolone; Rats	1988
A highly stable NADP-dependent isocitrate dehydrogenase from Thermus thermophilus HB8: purification and general properties. Biochimica et biophysica acta, 1989, Feb-24, Volume: 990, Issue:2 Topics: Amino Acids; Electrophoresis, Polyacrylamide Gel; Isocitrate Dehydrogenase; Isocitrates; Isoelectric Point; Kinetics; Magnesium; Manganese; Molecular Weight; NADP; Thermus	1989
Modification of NAD-dependent isocitrate dehydrogenase by the 2',3'-dialdehyde derivatives of NAD, NADH, NADP, and NADPH. Archives of biochemistry and biophysics, 1988, Aug-01, Volume: 264, Issue:2 Topics: Adenosine Diphosphate; Affinity Labels; Allosteric Regulation; Animals; Enzyme Reactivators; Isocitrate Dehydrogenase; Isocitrates; Isoelectric Focusing; Kinetics; Myocardium; NAD; NADP; Swine	1988
Characterization of an active site peptide modified by the substrate analogue 3-bromo-2-ketoglutarate on a single chain of dimeric NADP+-dependent isocitrate dehydrogenase. The Journal of biological chemistry, 1987, Sep-15, Volume: 262, Issue:26 Topics: Amino Acid Sequence; Animals; Binding Sites; Enzyme Activation; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Manganese; Manganese Compounds; NADP; Peptide Fragments; Sulfates; Swine	1987
Bioluminescent assay of NADPH-dependent isocitrate dehydrogenase and its substrates and cofactors. Analytical biochemistry, 1985, Nov-01, Volume: 150, Issue:2 Topics: Coenzymes; Enzyme Activation; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Luminescent Measurements; Magnesium; Manganese; NADP; Spectrophotometry, Ultraviolet	1985
Mechanism for the differential induction of mutation by S9 activated benzo[a]pyrene employing either a glucose-6-phosphate-dependent NADPH-regenerating system or an isocitrate-dependent system. Mutation research, 1982, Volume: 96, Issue:1 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cell Line; Cricetinae; Cricetulus; Female; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glucosephosphates; Isocitrate Dehydrogenase; Isocitrates; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; NADP; Ovary; Oxidation-Reduction; Rats	1982
Inhibition of bovine heart NAD-specific isocitrate dehydrogenase by reduced pyridine nucleotides: modulation of inhibition by ADP, NAD+, Ca2+, citrate, and isocitrate. Biochemistry, 1984, Jun-05, Volume: 23, Issue:12 Topics: Adenosine Diphosphate; Animals; Calcium; Cattle; Citrates; Citric Acid; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Magnesium; Myocardium; NAD; NADP; Oxidation-Reduction	1984
The differential effects of the carcinogen dimethylnitrosamine on isocitrate and 6-phosphogluconate metabolism in single intact cells. Biochimica et biophysica acta, 1982, Jul-22, Volume: 720, Issue:4 Topics: Animals; Dimethylnitrosamine; Gluconates; Isocitrates; L Cells; Mice; Microscopy, Fluorescence; NADP; Oxidation-Reduction; Spectrometry, Fluorescence	1982
Assay of magnesium in serum and urine with use of only one enzyme, isocitrate dehydrogenase (NADP+). Clinical chemistry, 1995, Volume: 41, Issue:9 Topics: Autoanalysis; Azo Compounds; Calcium Chloride; Edetic Acid; Egtazic Acid; Humans; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Magnesium; NADP; Oxidation-Reduction; Quality Control; Sensitivity and Specificity	1995
P450scc-dependent cholesterol metabolism in rat adrenal mitochondria is inhibited by low concentrations of matrix Ca2+. Archives of biochemistry and biophysics, 1995, Apr-01, Volume: 318, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenal Glands; Animals; Calcium; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cyclosporine; Desoxycorticosterone; Energy Metabolism; Female; In Vitro Techniques; Isocitrates; Mitochondria; NADP; Palmitic Acid; Palmitic Acids; Rats; Rats, Sprague-Dawley; Succinates; Succinic Acid	1995
Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. Science (New York, N.Y.), 1995, Jun-02, Volume: 268, Issue:5215 Topics: Binding Sites; Catalysis; Computer Graphics; Crystallography, X-Ray; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Mutagenesis, Site-Directed; NADP; Protein Conformation	1995
N-ethylmaleimide profiling of yeast NADP-dependent isocitrate dehydrogenase. Archives of biochemistry and biophysics, 1995, Jan-10, Volume: 316, Issue:1 Topics: Amino Acid Sequence; Binding Sites; Ethylmaleimide; Isocitrate Dehydrogenase; Isocitrates; Manganese; Molecular Sequence Data; NADP; Peptide Fragments; Sequence Homology, Amino Acid; Species Specificity; Yeasts	1995
Mechanistic stoichiometry of yeast mitochondrial oxidative phosphorylation. Biochemistry, 1994, Aug-16, Volume: 33, Issue:32 Topics: Adenosine Triphosphate; Ethanol; Isocitrates; Ketoglutaric Acids; Malates; Mitochondria; Models, Chemical; NADP; Oxidative Phosphorylation; Oxygen Consumption; Phosphorylation; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Succinates; Succinic Acid; Uncoupling Agents	1994
Isocitric and citric acid in human prostatic and seminal fluid: implications for prostatic metabolism and secretion. The Prostate, 1994, Volume: 24, Issue:3 Topics: Citrates; Citric Acid; Humans; Isocitrate Dehydrogenase; Isocitrates; Male; NADP; Oxidation-Reduction; Prostate; Semen; Trichloroacetic Acid	1994
Regulation of the soluble form of nicotinamide adenine dinucleotide phosphate-specific isocitrate dehydrogenase from lactating bovine mammary gland: effects of metabolites on activity and structure. Journal of dairy science, 1993, Volume: 76, Issue:12 Topics: Animals; Cattle; Circular Dichroism; Citrates; Citric Acid; Fatty Acids; Female; Homeostasis; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Lactation; Lipid Metabolism; Lipids; Magnesium; Mammary Glands, Animal; Manganese; Milk Proteins; NADP; Protein Conformation	1993
Competition for electron transfer between cytochromes P450scc and P45011 beta in rat adrenal mitochondria. Molecular and cellular endocrinology, 1993, Volume: 95, Issue:1-2 Topics: Adrenal Cortex; Adrenodoxin; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cosyntropin; Desoxycorticosterone; Electron Transport; Female; Ferredoxin-NADP Reductase; Isocitrates; Isoenzymes; Metyrapone; Mitochondria; NADP; Oxidation-Reduction; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Succinates; Succinic Acid	1993
Structure of isocitrate dehydrogenase with isocitrate, nicotinamide adenine dinucleotide phosphate, and calcium at 2.5-A resolution: a pseudo-Michaelis ternary complex. Biochemistry, 1993, Sep-14, Volume: 32, Issue:36 Topics: Binding Sites; Calcium; Isocitrate Dehydrogenase; Isocitrates; Macromolecular Substances; NADP; X-Ray Diffraction	1993
Determinants of performance in the isocitrate dehydrogenase of Escherichia coli. Protein science : a publication of the Protein Society, 1996, Volume: 5, Issue:2 Topics: Bacterial Proteins; Escherichia coli; Hydrogen Bonding; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Malates; Models, Molecular; Mutagenesis, Site-Directed; NADP; Substrate Specificity; Tartrates	1996
NADP-Isocitrate dehydrogenase from Pseudomonas nautica: kinetic constant determination and carbon limitation effects on the pool of intracellular substrates. Applied and environmental microbiology, 1998, Volume: 64, Issue:12 Topics: Isocitrate Dehydrogenase; Isocitrates; Kinetics; NADP; Pseudomonas; Pyruvates; Seawater; Species Specificity	1998
Evaluation by mutagenesis of the roles of His309, His315, and His319 in the coenzyme site of pig heart NADP-dependent isocitrate dehydrogenase. Biochemistry, 2002, Apr-30, Volume: 41, Issue:17 Topics: Amino Acid Sequence; Animals; Binding Sites; Circular Dichroism; Escherichia coli; Ferrous Compounds; Glutamine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; NADP; Phenylalanine; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Swine	2002
Characterization and regulation of NADP+-isocitrate dehydrogenase from Saccharopolyspora erythraea. Biotechnology letters, 2003, Volume: 25, Issue:14 Topics: Culture Media; Dimerization; Electrophoresis, Polyacrylamide Gel; Erythromycin; Fermentation; Fructose; Glucose; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Mycelium; NADP; Oxaloacetic Acid; Pyruvic Acid; Saccharopolyspora; Temperature	2003
Mitochondria of the Ehrlich ascites-tumour cell. 2. Diphosphopyridine nucleotide- and triphosphopyridine nucleotide-dependent oxidation of isocitrate. The Biochemical journal, 1961, Volume: 79 Topics: Ascites; Citrates; Coenzymes; Isocitrates; Mitochondria; NAD; NADP; Neoplasms; Oxidation-Reduction	1961
[Role of di- and triphosphopyridine nucleotides in the mitochondrial oxidation of isocitrate]. Biochimica et biophysica acta, 1961, Mar-04, Volume: 47 Topics: Citrates; Coenzymes; Isocitrates; Mitochondria; NADP; Oxidation-Reduction	1961
INTRACELLULAR DISTRIBUTION OF ISOCITRATE-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE-OXIDOREDUCTASE ACTIVITY DURING DEVELOPMENT OF THE CHICK EMBRYO. The Biochemical journal, 1963, Volume: 89 Topics: Animals; Brain; Chick Embryo; Citrates; Cytoplasm; DNA; Growth; Isocitrates; Liver; Myocardium; NADH, NADPH Oxidoreductases; NADP; Nitrogen; Oxidoreductases; Research; RNA	1963
PARATHYROID EXTRACT INHIBITION OF ISOCITRATE OXIDATION BY KIDNEY MITOCHONDRIA. Archives of biochemistry and biophysics, 1964, Volume: 108 Topics: Citrates; Injections, Intraperitoneal; Isocitrate Dehydrogenase; Isocitrates; Kidney; Metabolism; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxidative Phosphorylation; Parathyroid Hormone; Pharmacology; Research	1964
MITOCHONDRIAL PYRIDINE NUCLEOTIDES IN THE OXIDATION OF ISOCITRATE AND MALATE. Nature, 1965, Feb-13, Volume: 205 Topics: Citrates; Isocitrates; Liver; Malates; Metabolism; Mitochondria; NAD; NADP; Nucleotides; Oxidation-Reduction; Pyridines; Rats; Research	1965
Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity. The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32 Topics: Amino Acid Sequence; Binding Sites; Calcium; Crystallization; Cytosol; Escherichia coli; Gene Expression; Homeostasis; Humans; Isocitrate Dehydrogenase; Isocitrates; Magnesium; Models, Molecular; Molecular Sequence Data; Molecular Structure; NADP; Oxidation-Reduction; Phosphorylation; Protein Conformation; Protein Structure, Secondary; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Synchrotrons	2004
Aluminum decreases the glutathione regeneration by the inhibition of NADP-isocitrate dehydrogenase in mitochondria. Journal of cellular biochemistry, 2004, Dec-15, Volume: 93, Issue:6 Topics: Aluminum; Animals; Chickens; Cytosol; Glutathione; Glutathione Peroxidase; Isocitrate Dehydrogenase; Isocitrates; Liver; Malate Dehydrogenase; Mitochondria, Heart; NADP; Oxidation-Reduction	2004
Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases. The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6 Topics: Carbon; Carboxylic Acids; Catalysis; Cytosol; Electrophoresis; Genetic Complementation Test; Glucose; Glutamic Acid; Glycerol; Histidine; Hydrogen-Ion Concentration; Immunoblotting; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Lactates; NAD; NADP; Phenotype; Plasmids; Protein Isoforms; Saccharomyces cerevisiae; Time Factors	2005
Location of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase. The Journal of biological chemistry, 2005, Aug-26, Volume: 280, Issue:34 Topics: Adenine; Amino Acid Sequence; Animals; Arginine; Asparagine; Binding Sites; Circular Dichroism; Codon; Crystallography, X-Ray; Cytosol; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Magnesium; Mitochondria; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADP; Niacinamide; Oligonucleotides; Protein Binding; Swine; Threonine	2005
Variation of milk citrate with stage of lactation and de novo fatty acid synthesis in dairy cows. Journal of dairy science, 2006, Volume: 89, Issue:5 Topics: Acetates; Animals; Cattle; Chromatography, High Pressure Liquid; Citric Acid; Diet; Fats; Fatty Acid Synthases; Fatty Acids; Female; Isocitrates; Ketoglutaric Acids; Lactation; Lactose; Milk; Milk Proteins; NADP; Time Factors	2006
Role of phosphoenolpyruvate in the NADP-isocitrate dehydrogenase and isocitrate lyase reaction in Escherichia coli. Journal of bacteriology, 2007, Volume: 189, Issue:3 Topics: Escherichia coli; Isocitrate Dehydrogenase; Isocitrate Lyase; Isocitrates; Kinetics; NADP; Phosphoenolpyruvate	2007
Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction. Protein science : a publication of the Protein Society, 2008, Volume: 17, Issue:9 Topics: Amino Acid Sequence; Binding Sites; Calcium; Catalysis; Conserved Sequence; Decarboxylation; Dimerization; Hydrogen Bonding; Isocitrate Dehydrogenase; Isocitrates; Isoenzymes; Ketoglutaric Acids; Mitochondria; Models, Molecular; Molecular Sequence Data; NADP; Oxidation-Reduction; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Structure-Activity Relationship	2008
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. Nature genetics, 2008, Volume: 40, Issue:10 Topics: Case-Control Studies; Citric Acid Cycle; Female; Genes, Recessive; Humans; Isocitrate Dehydrogenase; Isocitrates; Lymphocytes; Male; NAD; NADP; Retinitis Pigmentosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2008
Single arginine mutation in two yeast isocitrate dehydrogenases: biochemical characterization and functional implication. PloS one, 2014, Volume: 9, Issue:12 Topics: Arginine; Catalysis; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Mutation; NADP; Saccharomyces cerevisiae; Structure-Activity Relationship; Yarrowia	2014
A unique homodimeric NAD⁺-linked isocitrate dehydrogenase from the smallest autotrophic eukaryote Ostreococcus tauri. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:6 Topics: Algal Proteins; Amino Acid Sequence; Base Sequence; Binding Sites; Blotting, Western; Chlorophyta; Circular Dichroism; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Magnesium; Manganese; Models, Molecular; Molecular Sequence Data; Molecular Structure; Molecular Weight; Mutation; NAD; NADP; Phylogeny; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity	2015
Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells. The Journal of clinical investigation, 2015, Oct-01, Volume: 125, Issue:10 Topics: Animals; Catalytic Domain; Cell Membrane; Cysteine Endopeptidases; Diabetes Mellitus, Type 2; Endopeptidases; Exocytosis; Gene Knockout Techniques; Glucose; Glutathione; HEK293 Cells; Homeostasis; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Isocitrate Dehydrogenase; Isocitrates; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; NADP; Organ Specificity; Recombinant Fusion Proteins; RNA Interference; Secretory Vesicles; Signal Transduction; Sumoylation	2015
Reductive carboxylation supports redox homeostasis during anchorage-independent growth. Nature, 2016, Apr-14, Volume: 532, Issue:7598 Topics: Cell Adhesion; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Citric Acid; Contact Inhibition; Cytosol; Extracellular Matrix; Glucose; Glutamic Acid; Glutamine; Homeostasis; Humans; Isocitrate Dehydrogenase; Isocitrates; Mitochondria; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spheroids, Cellular	2016
Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma. Scientific reports, 2016, 07-27, Volume: 6 Topics: Animals; Astrocytoma; Base Sequence; Binding Sites; Brain Neoplasms; Cell Line, Tumor; Glutarates; HEK293 Cells; Heterozygote; Humans; Isocitrate Dehydrogenase; Isocitrates; Mice; Mutation; NADP; Neoplasm Grading; Protein Multimerization	2016
Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei. Protein expression and purification, 2017, Volume: 138 Topics: Amino Acid Sequence; Cloning, Molecular; Crystallization; Escherichia coli; Gene Expression; Genetic Vectors; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Molecular Weight; NAD; NADP; Protozoan Proteins; Recombinant Fusion Proteins; Trypanosoma brucei brucei	2017
Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH). PLoS genetics, 2017, Volume: 13, Issue:8 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Humans; Isocitrate Dehydrogenase; Isocitrates; Mitochondria; NADP; Nerve Degeneration; Nerve Tissue Proteins; NF-E2 Transcription Factor; Oxidative Stress; Parkinson Disease	2017
Direct screening of enzyme activity using infrared matrix-assisted laser desorption electrospray ionization. Rapid communications in mass spectrometry : RCM, 2017, Nov-30, Volume: 31, Issue:22 Topics: Drug Discovery; Enzyme Assays; High-Throughput Screening Assays; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Models, Chemical; NADP; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2017
A high-throughput SAMDI-mass spectrometry assay for isocitrate dehydrogenase 1. The Analyst, 2020, Jun-07, Volume: 145, Issue:11 Topics: Cell Line, Tumor; Enzyme Assays; High-Throughput Screening Assays; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; NADP; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2020
SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2. Scientific reports, 2020, 05-26, Volume: 10, Issue:1 Topics: Acetylation; Cell Line, Tumor; Gene Silencing; Glutarates; Humans; Isocitrate Dehydrogenase; Isocitrates; Mitochondria; NADP; Nerve Tissue Proteins; Oxidation-Reduction; Sirtuin 3	2020
Purification and characterization of NADP-isocitrate dehydrogenase from skeletal muscle of Urocitellus richardsonii. Molecular and cellular biochemistry, 2023, Volume: 478, Issue:2 Topics: Animals; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Muscle, Skeletal; NADP; Sciuridae	2023
Capturing the Dynamic Conformational Changes of Human Isocitrate Dehydrogenase 1 (IDH1) upon Ligand and Metal Binding Using Hydrogen-Deuterium Exchange Mass Spectrometry. Biochemistry, 2023, 03-21, Volume: 62, Issue:6 Topics: Deuterium; Deuterium Exchange Measurement; Humans; Hydrogen Deuterium Exchange-Mass Spectrometry; Isocitrate Dehydrogenase; Isocitrates; Ligands; NADP	2023
Role of NADP Biochimie, 2023, Volume: 210 Topics: Animals; Freezing; Hypoxia; Isocitrate Dehydrogenase; Isocitrates; Muscle, Skeletal; NADP; Ranidae; Reactive Oxygen Species	2023