isobavachalcone has been researched along with dihydroguaiaretic-acid* in 1 studies
1 other study(ies) available for isobavachalcone and dihydroguaiaretic-acid
| Article | Year |
|---|---|
Compounds with DNA cleaving activity from Kadsura ananosma.
Two DNA cleavage agents, meso-dihydroguaiaretic acid (1) and isobavachalcone (2) together with the known alpha-ylangene, beta-sitosterol, daucosterol, pentacosane, hexacosanic acid and cerotic acid 1-monoglyceride were isolated from the stem barks of Kadsura ananosma Kerr for the first time. Compounds 1 and 2 showed relaxation of supercoiled DNA to nicked DNA. 1 represented a new structural type of DNA cleavage agent, while 2 was reported to show DNA strand-scission activity for the first time. 1 also showed significant cytotoxic effect on Hela and Leukemia cells in vitro. Topics: Cell Line, Tumor; Chalcones; DNA; DNA, Superhelical; Guaiacol; HeLa Cells; Humans; Kadsura; Leukemia; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nucleic Acid Conformation; Plant Bark; Plant Stems | 2006 |