isoarecolone methiodide has been researched along with arecoline in 4 studies
| Studies (isoarecolone methiodide) | Trials (isoarecolone methiodide) | Recent Studies (post-2010) (isoarecolone methiodide) | Studies (arecoline) | Trials (arecoline) | Recent Studies (post-2010) (arecoline) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 1,110 | 20 | 271 |
| Protein | Taxonomy | isoarecolone methiodide (IC50) | arecoline (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.6 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 1.011 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.9163 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.115 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garcha, HS; Reavill, C; Stolerman, IP; Waters, JA | 1 |
| Aronstam, RS; Spivak, CE; Waters, JA | 1 |
| Gund, TM; Hermsmeier, M; Liang, RF; Spivak, CE; Waters, JA; Yadav, JS | 1 |
| Reavill, C; Spivak, CE; Stolerman, IP; Waters, JA | 1 |
4 other study(ies) available for isoarecolone methiodide and arecoline
| Article | Year |
|---|---|
Behavioural effects of the nicotinic agonists N-(3-pyridylmethyl)pyrrolidine and isoarecolone in rats.
Topics: Animals; Arecoline; Behavior, Animal; Dose-Response Relationship, Drug; Male; Motor Activity; Nicotine; Pyridines; Pyrrolidines; Rats; Receptors, Nicotinic | 1990 |
Binding of semirigid nicotinic agonists to nicotinic and muscarinic receptors.
Topics: Animals; Arecoline; In Vitro Techniques; Male; Molecular Conformation; Neuromuscular Junction; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic; Structure-Activity Relationship; Torpedo | 1989 |
Synthesis, pharmacology, and molecular modeling studies of semirigid, nicotinic agonists.
Topics: Animals; Arecoline; Computer Simulation; Ganglionic Stimulants; In Vitro Techniques; Models, Molecular; Muscle Contraction; Rana pipiens; Software | 1988 |
Isoarecolone can inhibit nicotine binding and produce nicotine-like discriminative stimulus effects in rats.
Topics: Animals; Anura; Arecoline; Brain; Carbachol; Discrimination, Psychological; Male; Muscle Contraction; Nicotine; Rats; Rats, Inbred Strains | 1987 |