isoarecolone has been researched along with arecoline in 7 studies
| Studies (isoarecolone) | Trials (isoarecolone) | Recent Studies (post-2010) (isoarecolone) | Studies (arecoline) | Trials (arecoline) | Recent Studies (post-2010) (arecoline) |
|---|---|---|---|---|---|
| 7 | 0 | 1 | 1,110 | 20 | 271 |
| Protein | Taxonomy | isoarecolone (IC50) | arecoline (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.6 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 1.011 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.963 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.9163 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.115 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buccafusco, JJ; Gattu, M; Jackson, WJ; Terry, AV | 1 |
| Garcha, HS; Stolerman, IP; Whiteaker, P; Wonnacott, S | 1 |
| Mirza, NR; Pei, Q; Stolerman, IP; Zetterström, TS | 1 |
| Allen, DD; Beach, JW; Burgio, DE; McCurdy, CR; Metting, TL; Terry, AV | 1 |
| Hahn, B; Sharples, CG; Shoaib, M; Stolerman, IP; Wonnacott, S | 1 |
| Shoaib, M | 1 |
| Horenstein, NA; Papke, RL; Quadri, M; Shoaib, M; Stokes, C | 1 |
7 other study(ies) available for isoarecolone and arecoline
| Article | Year |
|---|---|
Isoarecolone-induced enhancement of delayed matching to sample performance in monkeys: role of nicotinic receptors.
Topics: Age Factors; Alkaloids; Animals; Arecoline; Azocines; Binding, Competitive; Dose-Response Relationship, Drug; Macaca fascicularis; Macaca nemestrina; Memory; Nicotinic Agonists; Quinolizines; Receptors, Nicotinic; Task Performance and Analysis | 1995 |
Locomotor activation and dopamine release produced by nicotine and isoarecolone in rats.
Topics: Amphetamine; Animals; Arecoline; Corpus Striatum; Dopamine; Dopamine Agents; Drug Interactions; Frontal Lobe; Locomotion; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
The nicotinic receptor agonists (-)-nicotine and isoarecolone differ in their effects on dopamine release in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arecoline; Dopamine; Male; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Inhibition of brain choline uptake by isoarecolone and lobeline derivatives: implications for potential vector-mediated brain drug delivery.
Topics: Animals; Arecoline; Biological Transport; Blood-Brain Barrier; Brain; Choline; Drug Delivery Systems; In Vitro Techniques; Lobeline; Male; Nicotinic Agonists; Perfusion; Rats; Rats, Inbred F344 | 1998 |
Attentional effects of nicotinic agonists in rats.
Topics: Animals; Arecoline; Attention; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cell Line; In Vitro Techniques; Isoxazoles; Male; Nicotinic Agonists; Photic Stimulation; Pyridines; Pyrrolidines; Radioligand Assay; Rats; Spiro Compounds | 2003 |
Effects of isoarecolone, a nicotinic receptor agonist in rodent models of nicotine dependence.
Topics: Animals; Arecoline; Behavior, Animal; Disease Models, Animal; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Self Administration; Tobacco Use Disorder | 2006 |
Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds.
Topics: Alkaloids; Animals; Areca; Arecoline; Behavior, Addictive; Cells, Cultured; Cholinergic Agents; Humans; Nicotinic Acids; Oocytes; Receptors, Muscarinic; Receptors, Nicotinic; Tobacco Use Disorder; Xenopus laevis | 2019 |