isoalantolactone has been researched along with alantolactone in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 12 (70.59) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Hadfield, JA; Lawrence, NJ; McGown, AT; Nduka, J; Pritchard, RG | 1 |
| Chen, W; Duan, JA; Guo, J; Liu, L; Lu, Y; Ma, H; Tang, Y | 1 |
| Gao, K; Ma, YY; Zhao, DG | 1 |
| Da Costa, FB; Klempnauer, KH; Schmidt, TJ; Schomburg, C; Schuehly, W | 1 |
| Bi, Z; Gao, S; Huang, K; Huang, M; Li, X; Liu, N; Liu, S; Liu, T; Liu, X; Lu, C; Mao, J; Miao, S; Ning, W; Qi, M; Qin, S; Sheng, P; Su, C; Sun, T; Wei, L; Wei, Y; Xiao, T; Yang, C; Yang, G; Zhao, L; Zhou, H | 1 |
| Alonso Blasi, N; Benezra, C; Fraginals, R; Lepoittevin, JP | 1 |
| Benezra, C; Geleick, H; Hausen, B; Klecak, G; Schulz, KH; Stampf, JL | 1 |
| Benezra, C; Gabriel-Robez, O; Grosshans, E; Schlewer, G; Stampf, JL | 1 |
| Huo, Y; Li, W; Li, X; Shi, H; Wang, M | 1 |
| Becnel, JJ; Cantrell, CL; Fronczek, FR; Pridgeon, JW | 1 |
| Ali, M; Khan, M; Li, J; Li, X; Rasul, A | 1 |
| Guo, C; Niu, K; Teng, S; Zhang, S | 1 |
| Li, X; Peng, Y; Wang, M; Xu, R; Zhou, G | 1 |
| Kim, J; Kim, JS; Lee, KW; Lim, SS; Seo, JY | 1 |
| Chen, L; Ge, G; Lan, G; Liu, Q; Mao, L; Ning, J; Shen, Y; Wang, S; Yang, L; Yang, N; Ye, J; Zhang, W; Zhou, B; Zhuo, Z | 1 |
| Li, X; Peng, Y; Wang, M; Xu, R | 1 |
| Lattoo, SK; Mudassir Jeelani, S; Prakash Gupta, A; Shahnawaz, M | 1 |
1 review(s) available for isoalantolactone and alantolactone
| Article | Year |
|---|---|
Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Humans; Lactones; Neoplasm Proteins; Neoplasms; Sesquiterpenes; Sesquiterpenes, Eudesmane | 2013 |
16 other study(ies) available for isoalantolactone and alantolactone
| Article | Year |
|---|---|
Cytotoxic Michael-type amine adducts of alpha-methylene lactones alantolactone and isoalantolactone.
Topics: Amines; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Combinatorial Chemistry Techniques; Humans; Inhibitory Concentration 50; K562 Cells; Lactones; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |
Discovery of estrogen receptor α modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells.
Topics: Animals; Cell Line, Tumor; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Drugs, Chinese Herbal; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Flavones; Humans; Mice; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Transfection | 2012 |
Structural investigation and biological activity of sesquiterpene lactones from the traditional Chinese herb Inula racemosa.
Topics: Antineoplastic Agents, Phytogenic; Crystallography, X-Ray; Drugs, Chinese Herbal; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Inula; Lactones; Molecular Structure; Plant Roots; Sesquiterpenes | 2013 |
Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships.
Topics: Acetyltransferases; Animals; Cell Line; Cell Survival; Chickens; Computer Simulation; Dose-Response Relationship, Drug; Gene Expression; Green Fluorescent Proteins; Inhibitory Concentration 50; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myb; Sesquiterpenes; Structure-Activity Relationship | 2013 |
Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.
Topics: Animals; Bleomycin; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Fibroblasts; High-Throughput Screening Assays; Idiopathic Pulmonary Fibrosis; Lactones; Mice; Molecular Structure; NIH 3T3 Cells; Sesquiterpenes; Sesquiterpenes, Eudesmane; Structure-Activity Relationship; Transforming Growth Factor beta1 | 2018 |
A murine in vitro model of allergic contact dermatitis to sesquiterpene alpha-methylene-gamma-butyrolactones.
Topics: Animals; Cross Reactions; Dermatitis, Allergic Contact; Disease Models, Animal; In Vitro Techniques; Lactones; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Sesquiterpenes; Sesquiterpenes, Eudesmane; Species Specificity | 1992 |
The sensitizing capacity of helenin and of two of its main constituents, the sesquiterpene lactones alantolactone and isoalantolactone: a comparison of epicutaneous and intradermal sensitizing methods in different strains of guinea pig.
Topics: Administration, Topical; Animals; Dermatitis, Contact; Female; Guinea Pigs; Injections, Intradermal; Lactones; Sesquiterpenes; Sesquiterpenes, Eudesmane | 1982 |
Allergic contact dermatitis to methylenelactones. Use of lymphocyte transformation test.
Topics: Allergens; Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Dermatitis, Atopic; Dermatitis, Contact; Guinea Pigs; Lactones; Lymphocyte Activation; Methods; Sesquiterpenes; Sesquiterpenes, Eudesmane | 1982 |
HPLC determination and NMR structural elucidation of sesquiterpene lactones in Inula helenium.
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Inula; Isomerism; Lactones; Magnetic Resonance Spectroscopy; Molecular Structure; Reproducibility of Results; Sesquiterpenes; Sesquiterpenes, Eudesmane | 2010 |
Structure-activity relationship studies on derivatives of eudesmanolides from Inula helenium as toxicants against Aedes aegypti larvae and adults.
Topics: Aedes; Animals; Crystallography, X-Ray; Insecticides; Inula; Lactones; Larva; Models, Molecular; Sesquiterpenes; Sesquiterpenes, Eudesmane; Structure-Activity Relationship | 2010 |
Simultaneous determination of sesquiterpene lactones isoalantolactone and alantolactone isomers in rat plasma by liquid chromatography with tandem mass spectrometry: application to a pharmacokinetic study.
Topics: Animals; Chromatography, Liquid; Lactones; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Sesquiterpenes, Eudesmane; Stereoisomerism; Tandem Mass Spectrometry | 2014 |
Pharmacokinetics, tissue distribution and excretion of isoalantolactone and alantolactone in rats after oral administration of Radix Inulae extract.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Gastropoda; Lactones; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Sesquiterpenes, Eudesmane; Tandem Mass Spectrometry; Tissue Extracts | 2015 |
Alantolactone and Isoalantolactone Prevent Amyloid β
Topics: Amyloid beta-Peptides; Animals; Avoidance Learning; Cognition Disorders; Cognitive Dysfunction; Lactones; Male; Maze Learning; Memory Disorders; Mice; Neurons; Neuroprotective Agents; Peptide Fragments; Scopolamine; Sesquiterpenes; Sesquiterpenes, Eudesmane | 2017 |
Metabolism and pharmacokinetics of alantolactone and isoalantolactone in rats: Thiol conjugation as a potential metabolic pathway.
Topics: Animals; Chromatography, Liquid; Cysteine; Glutathione; Humans; Lactones; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Sesquiterpenes, Eudesmane; Sulfhydryl Compounds; Tandem Mass Spectrometry | 2018 |
Intestinal Absorption of Isoalantolactone and Alantolactone, Two Sesquiterpene Lactones from Radix Inulae, Using Caco-2 Cells.
Topics: Administration, Oral; Biological Availability; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Intestinal Absorption; Inula; Lactones; Permeability; Plant Roots; Sesquiterpenes; Sesquiterpenes, Eudesmane | 2019 |
Phytochemical Diversity in Relation to Cytogenetic Variability in Inula racemosa Hook.f., an Endangered Medicinal Plant of Himalayas.
Topics: Chromatography, Liquid; Cytogenetic Analysis; Humans; Inula; Phytochemicals; Plants, Medicinal; Sesquiterpenes; Tandem Mass Spectrometry; Tetraploidy | 2022 |