isatin has been researched along with triazoles in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 20 (60.61) | 24.3611 |
| 2020's | 10 (30.30) | 2.80 |
| Authors | Studies |
|---|---|
| de Clercq, E; Nath, G; Pandeya, SN; Sriram, D | 1 |
| Kahveci, B | 1 |
| Bekircan, O; Bektas, H | 1 |
| Chibale, K; Gut, J; Hans, RH; Rosenthal, PJ | 1 |
| Hansen, TV; Jiang, Y | 1 |
| Chu, W; Mach, RH; Rothfuss, J; Zhou, D | 1 |
| Anand, A; Bedi, PM; Kaur, T; Kumar, V; Saxena, AK; Sharma, P; Singh, P | 1 |
| Esau, L; Kaur, M; Kumar, K; Kumar, V; Sagar, S | 1 |
| Faucher, RM; Haberkern, NT; Kumar, V; Land, KM; Patel, N; Raj, R; Singh, P | 1 |
| Gut, J; Kumar, V; Raj, R; Rosenthal, PJ | 1 |
| Amalvict, R; Benoit, N; Kumar, K; Kumar, V; Madamet, M; Pradines, B | 1 |
| Li, T; Que, Y; Wang, XS; Yao, C; Yu, C | 1 |
| Bedi, PM; Gupta, MK; Saxena, AK; Sharma, S | 1 |
| Balwani, S; Ghosh, B; Len, C; Malhotra, S; Mathur, D; Parmar, VS; Prasad, AK; Richards, NG; Sharma, PK; Singh, BK; Van der Eycken, EV | 1 |
| Liu, HM; Qi, PP; Tang, K; Wang, SQ; Yang, DX; Yu, B | 1 |
| Bathini, NB; Gannoju, S; Guggilapu, SD; Guntuku, L; K, DB; Nagarsenkar, A; Naidu, VGM | 1 |
| Bedi, PMS; Gupta, MK; Nepali, K; Saxena, AK; Sharma, S; Singh, H; Singh, JV | 1 |
| Chen, X; Feng, L; Guan, J; Jin, X; Wu, M; Xu, Y; Yang, X | 1 |
| Bains, T; Cheng, LW; Debnath, A; Kim, J; Kumar, S; Kumar, V; Land, KM; Tam, C; Won Kim, AS | 1 |
| Abid, M; Alajmi, MF; Ali, S; Aneja, B; El-Seedi, HR; Hassan, MI; Hussain, A; Khan, NS; Khan, P; Queen, A; Rehman, MT | 1 |
| Chen, L; Chen, Z; Fan, Y; Gao, F; Lu, G; Ma, L | 1 |
| Gao, F; Huang, G; Kong, F; Xiao, J; Ye, L | 1 |
| Aboagye, EO; Årstad, E; Carroll, L; Diocou, S; Gendron, T; Glaser, M; Pedley, RB; Rajkumar, V; Sander, K; Sin, PKB; Witney, TH; Yan, R | 1 |
| Liu, H; Wang, X; Xu, Z; Yang, M; Zhang, Y | 1 |
| Alcaro, S; Bagetta, D; Bartolini, M; Bolognesi, ML; Burke, AJ; Carreiro, EP; Decker, M; Fernández-Bolaños, JG; Hoffmann, M; López, Ó; Marques, CS; Monti, B; Petralla, S | 1 |
| Ahmed, HEA; Almehmadi, MA; Aouad, MR; Ihmaid, S; Omar, AM; Rezki, N; Shehata, AM | 1 |
| Awolade, P; Cele, N; Ebenezer, O; Gu, L; Gummidi, L; Kaur, M; Kerru, N; Palma, G; Singh, P | 1 |
| Ghosh, S; Jha, A; Ramarao, TA; Samanta, PK; Satpati, P; Sen, A | 1 |
| Chen, R; Guo, D; Liu, Y; Ma, T; Shi, X; Xu, Y; Xue, H; Zhang, J | 1 |
| Bedi, PMS; Bhagat, K; Chadha, R; Gulati, HK; Heer, S; Kaur, G; Kaur, K; Kumar, N; Sharma, A; Singh, A; Singh, H; Singh, JV | 1 |
| Chhabhaiya, H; Dadlani, VG; Somani, RR; Tripathi, PK | 1 |
| Kumar, A; Kumar, V; Lal, K; Rohila, Y | 1 |
| Jaglan, S; Kumar, A; Kumar, V; Kumari, K; Lal, K; Murtaza, M; Paul, AK; Yadav, S | 1 |
1 review(s) available for isatin and triazoles
| Article | Year |
|---|---|
A Mini Review on Pharmacological Significance of Isatin-1,2,3-Triazole Hybrids.
Topics: Anti-Bacterial Agents; Antioxidants; Antiviral Agents; Isatin; Structure-Activity Relationship; Triazoles | 2023 |
32 other study(ies) available for isatin and triazoles
| Article | Year |
|---|---|
Synthesis, antibacterial, antifungal and anti-HIV evaluation of Schiff and Mannich bases of isatin and its derivatives with triazole.
Topics: Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Cell Line; Fungi; Isatin; Magnetic Resonance Spectroscopy; Mannich Bases; Microbial Sensitivity Tests; Schiff Bases; Spectrophotometry, Infrared; Triazoles | 2000 |
Synthesis of 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their isatin-3-imine derivatives.
Topics: Imines; Isatin; Models, Biological; Triazoles | 2005 |
Synthesis of Schiff and Mannich bases of isatin derivatives with 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones.
Topics: Isatin; Magnetic Resonance Spectroscopy; Mannich Bases; Molecular Structure; Schiff Bases; Spectrophotometry, Infrared; Triazoles | 2008 |
Comparison of the antiplasmodial and falcipain-2 inhibitory activity of beta-amino alcohol thiolactone-chalcone and isatin-chalcone hybrids.
Topics: Antimalarials; Chalcone; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Isatin; Lactones; Malaria, Falciparum; Plasmodium falciparum; Triazoles | 2010 |
Isatin 1,2,3-triazoles as potent inhibitors against caspase-3.
Topics: Caspase Inhibitors; Enzyme Inhibitors; Isatin; Triazoles | 2011 |
Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: introduction of a hydrophilic group increases potency in a whole cell assay.
Topics: Caspase 3; Caspase Inhibitors; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Isatin; Protease Inhibitors; Recombinant Proteins; Structure-Activity Relationship; Triazoles | 2011 |
Azide-alkyne cycloaddition en route to novel 1H-1,2,3-triazole tethered isatin conjugates with in vitro cytotoxic evaluation.
Topics: Alkynes; Antineoplastic Agents; Azides; Cell Line, Tumor; Cycloaddition Reaction; Humans; Isatin; Triazoles | 2012 |
Synthesis of novel 1H-1,2,3-triazole tethered C-5 substituted uracil-isatin conjugates and their cytotoxic evaluation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isatin; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Triazoles; Uracil | 2012 |
Synthesis of 1H-1,2,3-triazole linked β-lactam-isatin bi-functional hybrids and preliminary analysis of in vitro activity against the protozoal parasite Trichomonas vaginalis.
Topics: Animals; Antiprotozoal Agents; beta-Lactams; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Isatin; Models, Chemical; Molecular Structure; Structure-Activity Relationship; Triazoles; Trichomonas vaginalis | 2013 |
1H-1,2,3-Triazole-tethered isatin-7-chloroquinoline and 3-hydroxy-indole-7-chloroquinoline conjugates: synthesis and antimalarial evaluation.
Topics: Antimalarials; Chloroquine; Drug Resistance; Hydrazines; Indoles; Inhibitory Concentration 50; Isatin; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Triazoles | 2014 |
1H-1,2,3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation.
Topics: Antimalarials; Ferrous Compounds; Isatin; Metallocenes; Structure-Activity Relationship; Triazoles | 2014 |
Enantioselective assembly of spirocyclic oxindole-dihydropyranones through NHC-catalyzed cascade reaction of isatins with N-hydroxybenzotriazole esters of α,β-unsaturated carboxylic acid.
Topics: Carboxylic Acids; Catalysis; Esters; Heterocyclic Compounds; Indoles; Isatin; Methane; Molecular Structure; Pyrones; Spiro Compounds; Stereoisomerism; Triazoles | 2015 |
Triazole linked mono carbonyl curcumin-isatin bifunctional hybrids as novel anti tubulin agents: Design, synthesis, biological evaluation and molecular modeling studies.
Topics: Binding Sites; Cell Line, Tumor; Cell Survival; Curcumin; Drug Design; Drug Screening Assays, Antitumor; Humans; Isatin; Microscopy, Fluorescence; Models, Molecular; Molecular Docking Simulation; Protein Structure, Tertiary; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators | 2015 |
Synthesis and anti-inflammatory activity evaluation of novel triazolyl-isatin hybrids.
Topics: Anti-Inflammatory Agents; Carbon-13 Magnetic Resonance Spectroscopy; Cells, Cultured; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Isatin; Proton Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared; Structure-Activity Relationship; Triazoles | 2016 |
Design and synthesis of isatin/triazole conjugates that induce apoptosis and inhibit migration of MGC-803 cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Isatin; Structure-Activity Relationship; Triazoles | 2016 |
Synthesis and apoptosis inducing studies of triazole linked 3-benzylidene isatin derivatives.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Design; Drug Screening Assays, Antitumor; Humans; Isatin; Mitochondrial Membranes; Reactive Oxygen Species; Triazoles | 2016 |
Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles | 2017 |
Design, Synthesis and In Vitro Anti-microbial Evaluation of Ethylene/ Propylene-1H-1,2,3-Triazole-4-Methylene-tethered Isatin-coumarin Hybrids.
Topics: Animals; Anti-Bacterial Agents; Cell Survival; Chlorocebus aethiops; Coumarins; Drug Design; Ethylenes; Gram-Negative Bacteria; Gram-Positive Bacteria; Isatin; Microbial Sensitivity Tests; Triazoles; Vero Cells | 2017 |
Highly Potent 1
Topics: Anaerobiosis; Antiprotozoal Agents; Entamoeba histolytica; Foodborne Diseases; Giardia lamblia; Humans; Inhibitory Concentration 50; Isatin; Metronidazole; Parasitic Diseases; Parasitic Sensitivity Tests; Sexually Transmitted Diseases; Triazoles; Trichomonas vaginalis; Tritrichomonas foetus | 2018 |
Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Hep G2 Cells; Humans; Hydrazones; Isatin; MCF-7 Cells; Neoplasm Metastasis; Oxidative Stress; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Triazoles | 2019 |
Synthesis and biological evaluation of moxifloxacin-acetyl-1,2,3-1H-triazole-methylene-isatin hybrids as potential anti-tubercular agents against both drug-susceptible and drug-resistant Mycobacterium tuberculosis strains.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Female; Isatin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Vero Cells | 2019 |
Design, synthesis and antibacterial activity evaluation of moxifloxacin-amide-1,2,3-triazole-isatin hybrids.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Design; Humans; Isatin; Molecular Docking Simulation; Molecular Structure; Moxifloxacin; Structure-Activity Relationship; Triazoles | 2019 |
One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[
Topics: Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Copper; Fluorine Radioisotopes; Heterografts; Humans; Iodine Radioisotopes; Isatin; Mice; Neoplasms; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Triazoles | 2019 |
Moxifloxacin-isatin Hybrids Tethered by 1,2,3-triazole and their Anticancer Activities.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Moxifloxacin; Polymerization; Structure-Activity Relationship; Triazoles; Tubulin | 2020 |
N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Hep G2 Cells; Horses; Humans; Isatin; Molecular Structure; Protein Aggregates; Structure-Activity Relationship; Triazoles | 2020 |
Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1,2,3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors: Synthesis, antitumor and mechanistic analyses.
Topics: Antineoplastic Agents; Apoptosis; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Isatin; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Quinazolines; Structure-Activity Relationship; Triazoles | 2020 |
Synthesis of 1H-1,2,3-Triazole-Linked Quinoline-Isatin Molecular Hybrids as Anti-Breast Cancer and Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) Agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Isatin; MCF-7 Cells; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Quinolines; Structure-Activity Relationship; Triazoles | 2021 |
Triazole based isatin derivatives as potential inhibitor of key cancer promoting kinases- insight from electronic structure, docking and molecular dynamics simulations.
Topics: Electronics; Humans; Isatin; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Protein Binding; Protein Kinase Inhibitors; Triazoles | 2021 |
Moxifloxacin Derivatives with Potential Antibacterial Activity against Methicillin- Resistant Staphylococcus Aureus (MRSA).
Topics: Anti-Bacterial Agents; DNA Topoisomerase IV; Fluoroquinolones; Isatin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Moxifloxacin; Triazoles | 2021 |
Design, synthesis, and biological evaluation of isatin-indole-3-carboxaldehyde hybrids as a new class of xanthine oxidase inhibitors.
Topics: Enzyme Inhibitors; Indoles; Isatin; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Triazoles; Xanthine Oxidase | 2022 |
Synthesis, molecular docking, and biological evaluation of novel 1,2,4-triazole-isatin derivatives as potential Mycobacterium tuberculosis shikimate kinase inhibitors.
Topics: Antitubercular Agents; HEK293 Cells; Humans; Isatin; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Shikimic Acid; Structure-Activity Relationship; Triazoles; Tuberculosis | 2022 |
Synthesis, antimicrobial, antibiofilm and computational studies of isatin-semicarbazone tethered 1,2,3-triazoles.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Escherichia coli; Isatin; Microbial Sensitivity Tests; Molecular Structure; Semicarbazones; Structure-Activity Relationship; Triazoles | 2023 |