isatin has been researched along with selegiline in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 18 (72.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toprakçí, M; Yelekçi, K | 1 |
| Bizzarri, B; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Granese, A; Orallo, F; Secci, D; Yáñez, M | 1 |
| Alcaro, S; Bolasco, A; Cardia, MC; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Distinto, S; Ferretti, R; Granese, A; Kirchmair, J; Langer, T; Maccioni, E; Orallo, F; Ortuso, F; Secci, D; Yáñez, M | 1 |
| Alcaro, S; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Granese, A; Orallo, F; Ortuso, F; Secci, D; Yáñez, M | 1 |
| Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Gallinella, B; Granese, A; Orallo, F; Sanna, ML; Secci, D; Yáñez, M | 1 |
| Alcaro, S; Bolasco, A; Fioravanti, R; Manna, F; Orallo, F; Ortuso, F; Rossi, F; Vitali, A; Yáñez, M | 1 |
| Alcaro, S; Borges, F; Gaspar, A; Orallo, F; Ortuso, F; Silva, T; Uriarte, E; Vina, D; Yáñez, M | 1 |
| Alcaro, S; Bolasco, A; Carradori, S; Chimenti, P; Ortuso, F; Secci, D; Yáñez, M | 1 |
| Bolasco, A; Carradori, S; D'Ascenzio, M; Nescatelli, R; Secci, D; Yáñez, M | 1 |
| Alcaro, S; Biava, M; Desideri, N; Fioravanti, R; Ortuso, F; Proietti Monaco, L; Yáñez, M | 2 |
| Agostinelli, E; Bonaiuto, E; Cozza, G; Di Paolo, ML; Fimognari, C; Hrelia, P; Marchetti, C; Milelli, A; Minarini, A; Tumiatti, V | 1 |
| Alcaro, S; Carradori, S; Cirilli, R; D'Ascenzio, M; De Monte, C; Mannina, L; Ortuso, F; Secci, D; Sobolev, AP; Yáñez, M | 1 |
| Estrada, M; Hripcsak, G; Matos, MJ; Rodríguez-Enríquez, F; Rodríguez-Franco, MI; Santana, L; Uriarte, E; Vilar, S; Viña, D | 1 |
| Besada, P; Borges, F; Costas-Lago, MC; Rodríguez-Enríquez, F; Terán, C; Uriarte, E; Vilar, S; Viña, D | 1 |
| Borges, F; Delogu, GL; Fontenla, JA; Hripcsak, G; Matos, MJ; Mayán, L; Munín, J; Pintus, F; Vilar, S; Viña, D | 1 |
| Cheng, K; Duan, Y; Han, J; Huang, X; Kong, H; Li, S; Liao, C; Lv, X; Tian, Y; Xie, Z | 1 |
| Clow, A; Dexter, D; Glover, V; Hussain, T; Sandler, M; Walker, M | 1 |
| Richardson, JS | 1 |
| Clow, A; Glover, V; Sandler, M | 1 |
| Endo, T; Hamaue, N; Hirafuji, M; Hiroshige, T; Machida, M; Minami, M; Ogata, A; Parvez, SH; Saito, H; Tashiro, K; Terado, M | 1 |
| Buneeva, O; Fedchenko, V; Glover, V; Gnedenko, O; Ivanov, Y; Medvedev, A; Medvedeva, M; Sandler, M | 1 |
| Buneeva, O; Fedchenko, V; Globa, A; Glover, V; Kaloshin, A; Kapitsa, I; Medvedev, A; Nerobkova, L; Val'dman, E | 1 |
| Buneeva, OA; Kopylov, AT; Medvedev, AE; Zgoda, VG | 1 |
| Buneeva, OA; Ivanova, EA; Kapitsa, IG; Kopylov, AT; Medvedev, AE; Zgoda, VG | 1 |
2 review(s) available for isatin and selegiline
| Article | Year |
|---|---|
On the functions of monoamine oxidase, the emotions, and adaptation to stress.
Topics: Adaptation, Psychological; Depressive Disorder; Emotions; Humans; Hypothalamus; Isatin; Limbic System; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Selegiline; Stress Disorders, Post-Traumatic; Stress, Psychological | 1993 |
Effects of dopaminergic drugs on superoxide dismutase: implications for senescence.
Topics: Aging; Animals; Corpus Striatum; Enzyme Induction; Free Radicals; Humans; Isatin; Life Expectancy; Nerve Degeneration; Parkinson Disease; Pergolide; Rats; Selegiline; Substantia Nigra; Superoxide Dismutase | 1993 |
23 other study(ies) available for isatin and selegiline
| Article | Year |
|---|---|
Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds.
Topics: Crystallography, X-Ray; Kinetics; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors | 2005 |
Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.
Topics: Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles | 2010 |
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrazones; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship; Thiazoles | 2010 |
Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.
Topics: Humans; Hydrazines; Hydrogen Peroxide; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2010 |
Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines.
Topics: Chromatography, High Pressure Liquid; Cyclohexanes; Humans; Hydrazines; Isoenzymes; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2010 |
Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors.
Topics: Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Prenylation; Pyrazoles; Structure-Activity Relationship | 2010 |
Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.
Topics: Amides; Chromones; Humans; Isoenzymes; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship; Water | 2011 |
Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives.
Topics: Coumarins; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2011 |
Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.
Topics: Dose-Response Relationship, Drug; Humans; Hydrazines; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2012 |
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors.
Topics: Cells, Cultured; Curcumin; Enzyme Activation; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase Inhibitors; Quantum Theory; Structure-Activity Relationship | 2013 |
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases.
Topics: Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Polyamines; Structure-Activity Relationship; Substrate Specificity | 2013 |
Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors.
Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Design; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Thiazoles | 2014 |
Potent and selective MAO-B inhibitory activity: amino- versus nitro-3-arylcoumarin derivatives.
Topics: Binding Sites; Coumarins; Humans; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Selegiline; Structure-Activity Relationship | 2015 |
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors.
Topics: Chromans; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Sensitivity and Specificity; Solvents; Structure-Activity Relationship | 2016 |
Synthesis and structure-activity relationship study of novel 3-heteroarylcoumarins based on pyridazine scaffold as selective MAO-B inhibitors.
Topics: Coumarins; Dose-Response Relationship, Drug; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyridazines; Structure-Activity Relationship | 2017 |
MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis,
Topics: | 2017 |
Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure.
Topics: Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Design; Humans; Isatin; Molecular Dynamics Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Isoforms; Structure-Activity Relationship | 2019 |
Pergolide can induce soluble superoxide dismutase in rat striata.
Topics: Animals; Brain Chemistry; Corpus Striatum; Cytosol; Dopamine; Enzyme Induction; Isatin; Levodopa; Male; Mitochondria; Pergolide; Rats; Rats, Wistar; Selegiline; Subcellular Fractions; Superoxide Dismutase | 1992 |
Comparative study of the effects of isatin, an endogenous MAO-inhibitor, and selegiline on bradykinesia and dopamine levels in a rat model of Parkinson's disease induced by the Japanese encephalitis virus.
Topics: Animals; Disease Models, Animal; Dopamine; Encephalitis Virus, Japanese; Hypokinesia; Isatin; Mice; Monoamine Oxidase Inhibitors; Parkinson Disease; Rats; Selegiline | 2004 |
Isatin interaction with glyceraldehyde-3-phosphate dehydrogenase, a putative target of neuroprotective drugs: partial agonism with deprenyl.
Topics: Animals; Biosensing Techniques; Dose-Response Relationship, Drug; Drug Interactions; Glyceraldehyde-3-Phosphate Dehydrogenases; Isatin; Monoamine Oxidase Inhibitors; Muscles; NAD; Protein Array Analysis; Protein Binding; Rabbits; Selegiline; Time Factors; Tritium | 2006 |
The effect of short-term administration of (-)-deprenyl and isatin on the expressions of some genes in the mouse brain cortex.
Topics: Animals; Cerebral Cortex; Gene Expression Regulation; Glyceraldehyde-3-Phosphate Dehydrogenases; Isatin; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Polymerase Chain Reaction; Selegiline; Superoxide Dismutase | 2008 |
[The effect of deprenyl and isatin administration to mice on the proteomic profile of liver isatin-binding proteins].
Topics: Animals; Binding, Competitive; Isatin; Ligands; Liver; Male; Metabolome; Mice, Inbred C57BL; Neuroprotective Agents; Protein Binding; Proteomics; Selegiline | 2018 |
[The effect of a neuroprotective dose of isatin or deprenyl to mice on the profile of brain isatin-binding proteins].
Topics: Animals; Brain; Carrier Proteins; Isatin; Mice; Neuroprotective Agents; Proteomics; Selegiline | 2019 |