isatin has been researched along with nutlin-3a in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barlev, NA; Daks, A; Davidovich, P; Demidov, O; Fedorova, O; Kartsev, V; Kriger, D; Lezina, L; Lomert, E; Melino, G; Petrova, V; Petukhov, A; Shuvalov, O; Tentler, D; Tribulovich, V; Uyanik, B | 1 |
| Grigoreva, T; Novikova, D; Romanova, A; Sagaidak, A; Tribulovich, V; Vorona, S | 1 |
2 other study(ies) available for isatin and nutlin-3a
| Article | Year |
|---|---|
Novel isatin-derived molecules activate p53 via interference with Mdm2 to promote apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Histones; Humans; Imidazoles; Isatin; Mice; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53 | 2018 |
Mdm2 inhibitors as a platform for the design of P-glycoprotein inhibitors.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Computer Simulation; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Isatin; Models, Molecular; Piperazines; Protein Binding; Proto-Oncogene Proteins c-mdm2; Quinolines; Structure-Activity Relationship | 2020 |