Compounds > isatin
Page last updated: 2024-08-17

isatin and clorgyline

isatin has been researched along with clorgyline in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's13 (86.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Bizzarri, B; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Granese, A; Orallo, F; Secci, D; Yáñez, M1
Alcaro, S; Bolasco, A; Cardia, MC; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Distinto, S; Ferretti, R; Granese, A; Kirchmair, J; Langer, T; Maccioni, E; Orallo, F; Ortuso, F; Secci, D; Yáñez, M1
Alcaro, S; Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Granese, A; Orallo, F; Ortuso, F; Secci, D; Yáñez, M1
Bolasco, A; Carradori, S; Chimenti, F; Chimenti, P; Cirilli, R; Gallinella, B; Granese, A; Orallo, F; Sanna, ML; Secci, D; Yáñez, M1
Alcaro, S; Bolasco, A; Fioravanti, R; Manna, F; Orallo, F; Ortuso, F; Rossi, F; Vitali, A; Yáñez, M1
Alcaro, S; Bolasco, A; Carradori, S; Chimenti, P; Ortuso, F; Secci, D; Yáñez, M1
Bolasco, A; Carradori, S; D'Ascenzio, M; Nescatelli, R; Secci, D; Yáñez, M1
Alcaro, S; Biava, M; Desideri, N; Fioravanti, R; Ortuso, F; Proietti Monaco, L; Yáñez, M2
Agostinelli, E; Bonaiuto, E; Cozza, G; Di Paolo, ML; Fimognari, C; Hrelia, P; Marchetti, C; Milelli, A; Minarini, A; Tumiatti, V1
Alcaro, S; Carradori, S; Cirilli, R; D'Ascenzio, M; De Monte, C; Mannina, L; Ortuso, F; Secci, D; Sobolev, AP; Yáñez, M1
Borges, F; Delogu, GL; Fontenla, JA; Hripcsak, G; Matos, MJ; Mayán, L; Munín, J; Pintus, F; Vilar, S; Viña, D1
Cheng, K; Duan, Y; Han, J; Huang, X; Kong, H; Li, S; Liao, C; Lv, X; Tian, Y; Xie, Z1
Abarbri, M; El Qami, A; Frlan, R; Gobec, S; Jismy, B; Knez, D; Kos, J; Pišlar, A1
Oxenkrug, GF; Requintina, PJ1

Other Studies

15 other study(ies) available for isatin and clorgyline

ArticleYear
Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:2

    Topics: Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles

2010
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.
    Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14

    Topics: Chromatography, High Pressure Liquid; Humans; Hydrazones; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship; Thiazoles

2010
Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.
    Bioorganic & medicinal chemistry, 2010, Aug-01, Volume: 18, Issue:15

    Topics: Humans; Hydrazines; Hydrogen Peroxide; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship

2010
Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines.
    Journal of medicinal chemistry, 2010, Sep-09, Volume: 53, Issue:17

    Topics: Chromatography, High Pressure Liquid; Cyclohexanes; Humans; Hydrazines; Isoenzymes; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Triazoles

2010
Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, Nov-15, Volume: 20, Issue:22

    Topics: Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Prenylation; Pyrazoles; Structure-Activity Relationship

2010
Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Coumarins; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship

2011
Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.
    European journal of medicinal chemistry, 2012, Volume: 58

    Topics: Dose-Response Relationship, Drug; Humans; Hydrazines; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship

2012
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors.
    European journal of medicinal chemistry, 2013, Volume: 59

    Topics: Cells, Cultured; Curcumin; Enzyme Activation; Humans; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase Inhibitors; Quantum Theory; Structure-Activity Relationship

2013
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases.
    European journal of medicinal chemistry, 2013, Volume: 70

    Topics: Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Polyamines; Structure-Activity Relationship; Substrate Specificity

2013
Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors.
    Bioorganic & medicinal chemistry, 2014, May-15, Volume: 22, Issue:10

    Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Design; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Thiazoles

2014
(E)-3-Heteroarylidenechroman-4-ones as potent and selective monoamine oxidase-B inhibitors.
    European journal of medicinal chemistry, 2016, Jul-19, Volume: 117

    Topics: Chromans; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Sensitivity and Specificity; Solvents; Structure-Activity Relationship

2016
MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis,
    MedChemComm, 2017, Sep-01, Volume: 8, Issue:9

    Topics:

2017
Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure.
    Bioorganic & medicinal chemistry letters, 2019, 04-15, Volume: 29, Issue:8

    Topics: Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Design; Humans; Isatin; Molecular Dynamics Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Isoforms; Structure-Activity Relationship

2019
Pyrimido[1,2-b]indazole derivatives: Selective inhibitors of human monoamine oxidase B with neuroprotective activity.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Antiparkinson Agents; Bromides; Coordination Complexes; Humans; Indazoles; Metals; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Neuroprotective Agents; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship; Tyramine

2021
The effect of MAO-A inhibition and cold-immobilization stress on N-acetylserotonin and melatonin in SHR and WKY rats.
    Journal of neural transmission. Supplementum, 1998, Volume: 52

    Topics: Animals; Clorgyline; Cold Temperature; Hydroxyindoleacetic Acid; Isatin; Isoenzymes; Male; Melatonin; Monoamine Oxidase Inhibitors; Pineal Gland; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Restraint, Physical; Serotonin; Species Specificity

1998