Compounds > irsogladine

irsogladine and interleukin-8

irsogladine has been researched along with interleukin-8 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashikaga, A; Fujita, T; Hirono, C; Kawaguchi, H; Komatsuzawa, H; Kurihara, H; Shiba, H; Shiba, Y; Sugai, M; Uchida, Y1
Ashikaga, A; Fujita, T; Hirata, R; Hirono, C; Iwata, T; Kawaguchi, H; Kishimoto, A; Kurihara, H; Shiba, H; Shiba, Y; Takeda, K; Uchida, Y1
Fujita, T; Hayashida, K; Kajiya, M; Kawaguchi, H; Kishimoto, A; Komatsuzawa, H; Kurihara, H; Shiba, H; Takeda, K1
Kageyama, K; Kyoi, T; Tajima, K; Zhang, X1
Abiko, Y; Fujita, T; Hayashida, K; Kajiya, M; Kawaguchi, H; Kishimoto, A; Kurihara, H; Matsuda, S; Ouhara, K; Shiba, H; Takeda, K; Uchida, Y1
Fujita, T; Kajiya, M; Kittaka, M; Kurihara, H; Miyagawa, T; Ouhara, K; Savitri, IJ; Shiba, H; Yamakawa, M1
Himi, T; Kakuki, T; Kohno, T; Kojima, T; Konno, T; Miyata, R; Nomura, K; Sawada, N; Takano, K1

Other Studies

7 other study(ies) available for irsogladine and interleukin-8

ArticleYear
Irsogladine maleate influences the response of gap junctional intercellular communication and IL-8 of human gingival epithelial cells following periodontopathogenic bacterial challenge.
    Biochemical and biophysical research communications, 2005, Jul-29, Volume: 333, Issue:2

    Topics: Aggregatibacter actinomycetemcomitans; Bacterial Outer Membrane Proteins; Cell Communication; Cells, Cultured; Dose-Response Relationship, Drug; Gap Junctions; Gingiva; Humans; Interleukin-8; Triazines

2005
Regulation of IL-8 by Irsogladine maleate is involved in abolishment of Actinobacillus actinomycetemcomitans-induced reduction of gap-junctional intercellular communication.
    Cytokine, 2006, Volume: 34, Issue:5-6

    Topics: Aggregatibacter actinomycetemcomitans; Cell Communication; Cells, Cultured; Connexin 43; Epithelial Cells; Gap Junctions; Humans; Interleukin-8; Triazines

2006
Irsogladine maleate abolishes the increase in interleukin-8 levels caused by outer membrane protein 29 from Aggregatibacter (Actinobacillus) actinomycetemcomitans through the ERK pathway in human gingival epithelial cells.
    Journal of periodontal research, 2008, Volume: 43, Issue:5

    Topics: Aggregatibacter actinomycetemcomitans; Bacterial Outer Membrane Proteins; Cells, Cultured; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gingiva; Humans; Interleukin-8; MAP Kinase Signaling System; Phosphorylation; Protein Kinase Inhibitors; Triazines

2008
Irsogladine maleate suppresses indomethacin-induced elevation of proinflammatory cytokines and gastric injury in rats.
    World journal of gastroenterology, 2008, Aug-14, Volume: 14, Issue:30

    Topics: Animals; Anti-Ulcer Agents; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Indomethacin; Interleukin-1beta; Interleukin-8; Male; Peroxidase; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Rats; Stomach Ulcer; Time Factors; Triazines; Tumor Necrosis Factor-alpha

2008
Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by Aggregatibacter actinomycetemcomitans.
    Biochemical pharmacology, 2010, May-15, Volume: 79, Issue:10

    Topics: Actins; Aggregatibacter actinomycetemcomitans; Animals; Cadherins; Chemokine CXCL1; Enzyme-Linked Immunosorbent Assay; Epithelium; Gingiva; Humans; Immunoblotting; Interleukin-8; Male; Neutrophil Infiltration; Neutrophils; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Inbred F344; Triazines

2010
Irsogladine maleate inhibits Porphyromonas gingivalis-mediated expression of toll-like receptor 2 and interleukin-8 in human gingival epithelial cells.
    Journal of periodontal research, 2015, Volume: 50, Issue:4

    Topics: Cell Line; Cells, Cultured; Epithelial Cells; Gene Knockdown Techniques; Gingiva; Humans; Immunity, Innate; Immunosuppressive Agents; Interleukin-8; Lipopolysaccharides; Porphyromonas gingivalis; RNA, Small Interfering; Toll-Like Receptor 2; Triazines

2015
Irsogladine maleate regulates gap junctional intercellular communication-dependent epithelial barrier in human nasal epithelial cells.
    The Journal of membrane biology, 2015, Volume: 248, Issue:2

    Topics: Antineoplastic Agents; Cell Communication; Epithelial Cells; Gap Junctions; Gene Expression; Glycyrrhetinic Acid; Humans; Interleukin-8; Nasal Mucosa; Oleic Acids; Tight Junction Proteins; Triazines; Tumor Necrosis Factor-alpha

2015