irinotecan has been researched along with warfarin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Doi, S; Ikegami, Y; Kitazaki, T; Kohno, S; Mizuta, Y; Murase, K; Nakamura, Y; Nakatomi, K; Oka, M; Ross, DD; Shiozawa, K; Soda, H; Tsurutani, J; Yoshida, H; Yoshikawa, M | 1 |
| Hanioka, N; Jinno, H; Koeda, A; Nagaoka, K; Naito, S; Narimatsu, S; Tanabe, N; Tanaka-Kagawa, T | 1 |
| Kotsuji, F; Kurokawa, T; Masada, M; Matsunaga, A; Nakamura, T; Sawamura, Y; Shinagawa, A; Tsuyoshi, H; Yano, R; Yoneda, M; Yoshida, Y | 1 |
| Bito, T; Fabian, G; Farago, N; Feher, LZ; Katona, RL; Kitajka, K; Kulin, S; Nagy, LI; Puskas, LG; Tiszlavicz, L; Tubak, V | 1 |
| Begg, EJ; Helsby, NA; Jensen, BP | 1 |
| Guo, M; Hou, J; Lu, Y; Rong, WT; Wang, DF; Wang, Y; Xu, Q; Yu, SQ | 1 |
| Pang, LQ; Qin, ZS; Wu, K; Xia, TF; Zhang, XS; Zhao, ZQ | 1 |
| Jaggi, M; Joshi, V; Negi, LM; Ronodip, K; Talegaonkar, S | 1 |
| Guo, D; Han, X; Ling, Y; Luo, J; Shi, C; Wang, L; Xu, G | 1 |
| Finel, M; Ge, GB; Järvinen, E; Troberg, J; Yang, L | 1 |
2 review(s) available for irinotecan and warfarin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacogenetics of drug-metabolizing enzymes: the prodrug hypothesis.
Topics: Aryl Hydrocarbon Hydroxylases; Azathioprine; Camptothecin; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Enzymes; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Irinotecan; Methyltransferases; Mixed Function Oxygenases; Prodrugs; Tamoxifen; Ticlopidine; Vitamin K Epoxide Reductases; Warfarin | 2012 |
16 other study(ies) available for irinotecan and warfarin
| Article | Year |
|---|---|
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic.
Topics: Aminocoumarins; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Coumarins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Irinotecan; Lung Neoplasms; Mitoxantrone; Neoplasm Proteins; Novobiocin; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured | 2004 |
Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.
Topics: Amino Acid Sequence; Animals; Camptothecin; Coumarins; Estradiol; Gene Expression; Glucuronosyltransferase; Humans; Irinotecan; Macaca fascicularis; Molecular Sequence Data; Recombinant Proteins; Sequence Alignment | 2010 |
Transient elevation of international normalized ratio during cisplatin-based chemotherapy in patients who are taking warfarin.
Topics: Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Interactions; Drug Monitoring; Female; Genital Neoplasms, Female; Humans; International Normalized Ratio; Irinotecan; Middle Aged; Thromboembolism; Treatment Outcome; Venous Thrombosis; Warfarin | 2011 |
High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Brain; Camptothecin; Coumarins; Doxorubicin; Female; Heart; Irinotecan; Kidney; Mice, Inbred BALB C; Myocardium; Phenylenediamines; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Rotenone; Sulfasalazine; Toxicogenetics; Transcriptome; Xenobiotics | 2011 |
Mechanisms of chitosan-coated poly(lactic-co-glycolic acid) nanoparticles for improving oral absorption of 7-ethyl-10-hydroxycamptothecin.
Topics: Absorption; Animals; Caco-2 Cells; Calorimetry, Differential Scanning; Camptothecin; Cell Death; Chitosan; Coated Materials, Biocompatible; Coumarins; Enterocytes; HT29 Cells; Humans; Intestines; Irinotecan; Kinetics; Lactic Acid; Male; Nanoparticles; Particle Size; Perfusion; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Rhodamine 123; Spectroscopy, Fourier Transform Infrared; Static Electricity; X-Ray Diffraction | 2013 |
Herb-drug interaction between irinotecan and psoralidin-containing herbs.
Topics: Animals; Benzofurans; Camptothecin; Colon; Coumarins; Dose-Response Relationship, Drug; Herb-Drug Interactions; Humans; Irinotecan; Male; Mice; Mice, 129 Strain | 2015 |
Hyaluronic acid decorated lipid nanocarrier for MDR modulation and CD-44 targeting in colon adenocarcinoma.
Topics: Adenocarcinoma; Camptothecin; Colonic Neoplasms; Coumarins; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Irinotecan; Lipids; Nanoparticles; Thiazoles | 2015 |
Functional-segregated coumarin-containing telodendrimer nanocarriers for efficient delivery of SN-38 for colon cancer treatment.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Coumarins; Dendrimers; Drug Carriers; Humans; Irinotecan; Molecular Dynamics Simulation; Nanostructures | 2015 |
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
Topics: Animals; Blotting, Western; Camptothecin; Chromatography, High Pressure Liquid; Coumarins; Diclofenac; Estradiol; Estrone; Flavonoids; Glucuronosyltransferase; Humans; Hymecromone; Intestinal Mucosa; Irinotecan; Kinetics; Microsomes, Liver | 2017 |