Page last updated: 2024-08-24

irinotecan and thiazoles

irinotecan has been researched along with thiazoles in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Bai, F; Hara, N; Kawasaki, M; Mizuno, K; Nakanishi, Y; Pei, XH; Takayama, K; Tsuruta, N1
Hotta, T; Ishimoto, K; Iwahashi, M; Matsuda, K; Tanaka, H; Tani, M; Tanimura, H; Tsunoda, T; Yamaue, H1
Fukumoto, H; Kanzawa, F; Koh, Y; Koizumi, F; Nakamura, T; Nishio, K; Saijo, N; Tatsumi, Y; Yoshioka, T1
Akeshima, R; Iba, T; Itamochi, H; Kamazawa, S; Kanamori, Y; Kigawa, J; Sultana, H; Terakawa, N1
Deguchi, N; Murai, M; Nonaka, S; Ueno, M; Yamazaki, R1
André, A; Braekman, JC; Bruyneel, F; Darro, F; Decaestecker, C; Dewelle, J; El Yazidi, M; Guissou, P; Kiss, R; Nacoulma, O; Simon, G; Tuti, J; Van Quaquebeke, E1
Cusano, G; D'Incalci, M; Di Francesco, AM; Forestieri, D; Meco, D; Patriarca, V; Pisano, C; Riccardi, R; Servidei, T; Zucchetti, M1
Allen, JE; Brown, JM; Daniel, CJ; Dicker, DT; Dolloff, NG; Dorsey, JF; El-Deiry, WS; Furth, EE; Hart, LS; Jee, DI; Klein, PS; Kuribayashi, K; Liu, JJ; Liu, YY; Mayes, PA; Sears, RC1
Huang, J; Mao, W; Shen, Y; Sui, M; Wang, J; Wu, X; Zhang, H1
Jaggi, M; Joshi, V; Negi, LM; Ronodip, K; Talegaonkar, S1
Adachi, T; Azuma, T; Eguchi, S; Enjoji, A; Enjoji, T; Fujioka, H; Fukui, S; Haraguchi, M; Hashimoto, T; Hayashida, N; Hidaka, M; Ikebe, A; Inoue, Y; Ito, S; Kamohara, Y; Kanetaka, K; Kawakami, S; Kitajima, T; Kobayashi, K; Kosaka, T; Kuba, S; Kuroki, T; Matsuo, M; Mine, Y; Morita, M; Moriuchi, H; Natsuda, K; Okada, K; Okada, S; Ono, S; Sakimura, C; Soyama, A; Suto, R; Takatsuki, M; Taniguchi, K; Tetsuo, H; Torashima, Y; Yamaguchi, I; Yamaguchi, S; Yamanouchi, K1
Ardakani, YH; Dinarvand, R; Rezaei, M; Shirazi, AS; Varshochian, R1

Trials

1 trial(s) available for irinotecan and thiazoles

ArticleYear
S-1 and CPT-11 Plus Ramucirumab (IRIS+Rmab) as Second-Line Chemotherapy for Patients with Oxaliplatin-Refractory Metastatic Colorectal Cancer (mCRC): A Multicenter Phase II Study in Japan (N-DOCC-F-C-1701).
    The Kurume medical journal, 2020, Jul-01, Volume: 66, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Colorectal Neoplasms; Drug Resistance, Neoplasm; Humans; Irinotecan; Oxaliplatin; Quality of Life; Ramucirumab; Thiazoles

2020

Other Studies

11 other study(ies) available for irinotecan and thiazoles

ArticleYear
Effect of CPT-11 in combination with other anticancer agents in lung cancer cells.
    Anti-cancer drugs, 1997, Volume: 8, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Survival; Drug Interactions; Drug Screening Assays, Antitumor; Humans; Irinotecan; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1997
In vitro augmentation of antitumor effect in combination with CPT-11 and CDDP for human colorectal cancer.
    Journal of surgical oncology, 2000, Volume: 73, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Coloring Agents; Drug Synergism; Female; Humans; Irinotecan; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2000
In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; DNA Topoisomerases, Type I; Drug Synergism; Enzyme Inhibitors; Humans; Irinotecan; Lung Neoplasms; Organoplatinum Compounds; Thiazoles; Thiazolidinediones; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2001
Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:6

    Topics: Adenocarcinoma, Clear Cell; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cisplatin; Coloring Agents; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Female; Glutathione; Humans; Inhibitory Concentration 50; Irinotecan; Mitochondrial Proteins; Mitomycin; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
SN-38 induces cell cycle arrest and apoptosis in human testicular cancer.
    European urology, 2002, Volume: 42, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle; Cell Line; Cisplatin; DNA; Etoposide; G1 Phase; Humans; In Situ Nick-End Labeling; Irinotecan; Male; Testicular Neoplasms; Tetrazolium Salts; Thiazoles

2002
Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses.
    Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

    Topics: Animals; Antineoplastic Agents; Calotropis; Camptothecin; Cardenolides; Cell Line, Tumor; Cell Proliferation; Cerebral Cortex; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Humans; Irinotecan; Magnetic Resonance Spectroscopy; Maximum Tolerated Dose; Mice; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Swine; Thiazoles

2005
Antitumor activity and pharmacokinetics of oral gimatecan on pediatric cancer xenografts.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Cell Line, Tumor; Cell Proliferation; Child; Chromatography, High Pressure Liquid; Half-Life; Humans; Irinotecan; Male; Mice; Mice, Nude; Neuroblastoma; Rhabdomyosarcoma; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays

2010
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
    Cancer research, 2011, Aug-01, Volume: 71, Issue:15

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; CDC2 Protein Kinase; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitor of Apoptosis Proteins; Irinotecan; Mice; Mice, Nude; Neoplasm Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-myb; Pyrimidines; Recombinant Proteins; RNA, Small Interfering; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2011
Novel SN38 conjugate-forming nanoparticles as anticancer prodrug: in vitro and in vivo studies.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Mar-10, Volume: 166, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles; Nanoparticles; Prodrugs; Solubility; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays

2013
Hyaluronic acid decorated lipid nanocarrier for MDR modulation and CD-44 targeting in colon adenocarcinoma.
    International journal of biological macromolecules, 2015, Volume: 72

    Topics: Adenocarcinoma; Camptothecin; Colonic Neoplasms; Coumarins; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Irinotecan; Lipids; Nanoparticles; Thiazoles

2015
SN38 loaded nanostructured lipid carriers (NLCs); preparation and in vitro evaluations against glioblastoma.
    Journal of materials science. Materials in medicine, 2021, Jun-30, Volume: 32, Issue:7

    Topics: Calorimetry, Differential Scanning; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Excipients; Glioblastoma; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Irinotecan; Lipids; Microscopy, Confocal; Nanoparticles; Nanostructures; Particle Size; Solubility; Solvents; Tetrazolium Salts; Thiazoles

2021