Page last updated: 2024-08-24

irinotecan and selenomethionine

irinotecan has been researched along with selenomethionine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, S; Durrani, FA; Rustum, YM1
Altundag, K; Altundag, O; Gundeslioglu, O; Gunduz, M; Silay, YS; Yigitbasi, OG1
Cao, S; Durrani, FA; Fakih, M; Rustum, YM1
Azrak, RG; Badmaev, V; Creaven, PJ; Fakih, MG; Lawrence, D; Pendyala, L; Prey, JD; Reid, ME; Rustum, YM; Smith, PF1
Badmaev, V; Brady, W; Creaven, PJ; Fakih, MG; Pendyala, L; Prey, JD; Ross, ME; Rustum, YM; Smith, PF1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1

Reviews

1 review(s) available for irinotecan and selenomethionine

ArticleYear
Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cysteine; Drug Synergism; Humans; Irinotecan; Mice; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Selenomethionine

2005

Trials

2 trial(s) available for irinotecan and selenomethionine

ArticleYear
A phase I and pharmacokinetic study of fixed-dose selenomethionine and irinotecan in solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Feb-15, Volume: 12, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Camptothecin; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Irinotecan; Male; Middle Aged; Nausea; Neoplasms; Selenomethionine; Treatment Outcome

2006
A Phase I and pharmacokinetic study of selenomethionine in combination with a fixed dose of irinotecan in solid tumors.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Irinotecan; Male; Middle Aged; Neoplasms; Selenomethionine; Treatment Outcome

2008

Other Studies

3 other study(ies) available for irinotecan and selenomethionine

ArticleYear
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoselenium Compounds; Radiation-Sensitizing Agents; Selenium; Selenocysteine; Selenomethionine; Time Factors

2004
Selenium supplementation may increase the efficacy of cetuximab in metastatic colorectal cancer patients.
    Medical hypotheses, 2005, Volume: 64, Issue:6

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Depression, Chemical; Dietary Supplements; Dinoprostone; Drug Synergism; ErbB Receptors; Humans; Irinotecan; Membrane Proteins; Models, Biological; Neoplasm Proteins; Organoplatinum Compounds; Oxaliplatin; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Processing, Post-Translational; Selenium; Selenomethionine; Signal Transduction

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010