irinotecan has been researched along with quercetin in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ikegami, Y; Ishikawa, T; Mitomo, H; Sano, K; Sawada, S; Yoshida, H; Yoshikawa, M | 1 |
| Cao, J; Chan, E; Chen, X; Duan, W; Hu, ZP; Huang, M; Wen, JY; Yang, XX; Yu, XQ; Zhou, SF | 1 |
| Basic, I; Benkovic, V; Bevanda, M; Brozovic, G; Dikic, D; Horvat Knezevic, A; Knezevic, F; Orsolic, N | 1 |
| Awasthi, A; Bansal, T; Jaggi, M; Khar, RK; Talegaonkar, S | 1 |
| Benković, V; Dikić, D; Karabeg, S; Knežević, AH; Kopjar, N; Lisičić, D; Oršolić, N | 1 |
| Ding, LL; Dou, W; Zhang, JJ | 1 |
| Hou, YC; Lei, CS; Lin, MT; Pai, MH; Yeh, SL | 1 |
| Cui, H; Liu, Y; Meng, Q; Zhang, F; Zhang, H; Zhao, L | 1 |
| Marsh, DT; Smid, SD | 1 |
12 other study(ies) available for irinotecan and quercetin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Transport of SN-38 by the wild type of human ABC transporter ABCG2 and its inhibition by quercetin, a natural flavonoid.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Camptothecin; Cell Membrane; Cells, Cultured; Drug Resistance; Glucuronides; Humans; Irinotecan; Mutation; Neoplasm Proteins; Quercetin | 2004 |
A mechanistic study on altered pharmacokinetics of irinotecan by St. John's wort.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Bridged Bicyclo Compounds; Camptothecin; Cell Line, Tumor; Cell Proliferation; Glucuronides; Hypericum; Irinotecan; Male; Microsomes, Liver; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Rats; Rats, Sprague-Dawley; Terpenes | 2007 |
Enhanced antitumor activity of irinotecan combined with propolis and its polyphenolic compounds on Ehrlich ascites tumor in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Ehrlich Tumor; Drug Synergism; Drug Therapy, Combination; Flavanones; Flavonoids; Irinotecan; Male; Mice; Phenols; Polyphenols; Propolis; Quercetin | 2007 |
Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: possible contribution of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Availability; Biological Transport; Caco-2 Cells; Camptothecin; Drug Screening Assays, Antitumor; Female; Humans; Intestinal Absorption; Irinotecan; Quercetin; Rats; Rats, Wistar | 2008 |
Synergistic effects of irinotecan and flavonoids on Ehrlich ascites tumour-bearing mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Ehrlich Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Flavanones; Hepatocytes; Injections, Intraperitoneal; Irinotecan; Kidney; Male; Mice; Peritoneal Cavity; Quercetin | 2011 |
[Effects of isorhamnetin on CYP3A4 and herb-drug interaction].
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Hep G2 Cells; Herb-Drug Interactions; Humans; Irinotecan; Pregnane X Receptor; Quercetin; Receptors, Steroid; RNA, Messenger; Transcriptional Activation; Up-Regulation | 2012 |
Effects of quercetin combined with anticancer drugs on metastasis-associated factors of gastric cancer cells: in vitro and in vivo studies.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Survival; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Injections, Intraperitoneal; Irinotecan; Mice, Nude; Neoplasm Proteins; Quercetin; Random Allocation; Specific Pathogen-Free Organisms; Stomach Neoplasms; Topoisomerase I Inhibitors; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Combined and targeted drugs delivery system for colorectal cancer treatment: Conatumumab decorated, reactive oxygen species sensitive irinotecan prodrug and quercetin co-loaded nanostructured lipid carriers.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Survival; Chemistry, Pharmaceutical; Drug Carriers; Drug Combinations; Drug Liberation; Drug Stability; Drug Synergism; HT29 Cells; Humans; Irinotecan; Lipids; Mice; Nanoparticle Drug Delivery System; Nanostructures; Particle Size; Prodrugs; Quercetin; Reactive Oxygen Species; Surface Properties; Xenograft Model Antitumor Assays | 2022 |
The semi-synthetic flavonoid 2',3',4'-trihydroxyflavone (2-D08) inhibits both SN-38- and cytokine-evoked increases in epithelial barrier permeability in an
Topics: Antioxidants; Caco-2 Cells; Cytokines; Flavonoids; Humans; Inflammation; Intestinal Mucosa; Irinotecan; Mucositis; Permeability; Quercetin | 2022 |