Page last updated: 2024-08-24

irinotecan and organophosphonates

irinotecan has been researched along with organophosphonates in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's5 (55.56)29.6817
2010's0 (0.00)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Diasio, RB; Stagg, MP1
Burris, HA; Eckardt, JR; Fields, S; O'Rourke, T; Rodriguez, GI; Rothenberg, ML; Weiss, GR1
Innocenti, F; Iyer, L; Ratain, MJ2
Bian, JS; Boelsterli, UA; Chan, E; Chan, SY; Duan, W; Ho, PC; Huang, M; Li, X; Tan, TM; Tian, Q; Xiong, W; Yang, H; Zhang, J; Zhou, S; Zhu, YZ1
Darro, F; Dewelle, J; Dumont, P; El Yazidi, M; Gaussin, JF; Kiss, R; Lefranc, F; Mahieu, T; Mijatovic, T; Ribaucour, F; Sauvage, S; Simon, G; Tuti, J; Van Quaquebeke, E; Van Vynckt, F1
Corona, G; Innocenti, F; Sandron, S; Sartor, I; Tirelli, U; Toffoli, G; Vaccher, E1
Huang, R; Huang, X; Kong, J; Wang, H; Wang, M; Wang, Y; You, Q; Yu, C; Zhang, H1
Davies, DW; Diao, Y; Kafle, P; Khasbaatar, A; Punjani, S; Sanghavi, R1

Reviews

3 review(s) available for irinotecan and organophosphonates

ArticleYear
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990
New anticancer agents.
    Cancer chemotherapy and biological response modifiers, 1994, Volume: 15

    Topics: Adenine; Animals; Antineoplastic Agents; Camptothecin; Deoxycytidine; Gemcitabine; Humans; Imides; Indoles; Irinotecan; Isoquinolines; Naphthalimides; Organophosphonates; Pyridines; Topotecan; Vinblastine; Vinorelbine

1994
Pharmacogenetics: a tool for individualizing antineoplastic therapy.
    Clinical pharmacokinetics, 2000, Volume: 39, Issue:5

    Topics: Adenine; Antineoplastic Agents; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Imides; Irinotecan; Isoquinolines; Mercaptopurine; Methyltransferases; Naphthalimides; Organophosphonates; Oxidoreductases; Pharmacogenetics; Phenotype

2000

Trials

1 trial(s) available for irinotecan and organophosphonates

ArticleYear
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990

Other Studies

6 other study(ies) available for irinotecan and organophosphonates

ArticleYear
Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:4 Pt 2

    Topics: Adenine; Antineoplastic Agents; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Organophosphonates; Pharmacogenetics; Polymorphism, Genetic

2001
Human multidrug resistance associated protein 4 confers resistance to camptothecins.
    Pharmaceutical research, 2005, Volume: 22, Issue:11

    Topics: Adenine; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line; Drug Resistance, Neoplasm; Glutathione; Humans; Irinotecan; Methotrexate; Multidrug Resistance-Associated Proteins; Organophosphonates; Paclitaxel

2005
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.
    Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17

    Topics: Acetamides; Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Camptothecin; Cell Line, Tumor; Cellular Senescence; Deoxycytidine; Drug Screening Assays, Antitumor; Erythrocyte Count; Female; Gemcitabine; Humans; Imides; Irinotecan; Isoquinolines; Leukocyte Count; Maximum Tolerated Dose; Mice; Naphthalimides; Neoplasm Transplantation; Organophosphonates; Platelet Count; Structure-Activity Relationship; Topoisomerase I Inhibitors; Urea

2007
Lopinavir-ritonavir dramatically affects the pharmacokinetics of irinotecan in HIV patients with Kaposi's sarcoma.
    Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:4

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Antiretroviral Therapy, Highly Active; Area Under Curve; Camptothecin; Drug Therapy, Combination; HIV Infections; Humans; Irinotecan; Lamivudine; Lopinavir; Male; Middle Aged; Organophosphonates; Pyrimidinones; Ritonavir; Sarcoma, Kaposi; Tenofovir; White People

2008
Synthesis, mechanisms of action, and toxicity of novel aminophosphonates derivatives conjugated irinotecan in vitro and in vivo as potent antitumor agents.
    European journal of medicinal chemistry, 2020, Mar-01, Volume: 189

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Female; Humans; In Vitro Techniques; Irinotecan; Mice; Mice, Inbred BALB C; Mice, Nude; Organophosphonates; Ovarian Neoplasms; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
Drastic Modulation of Molecular Packing and Intrinsic Dissolution Rates by Meniscus-Guided Coating of Extremely Confined Pharmaceutical Thin Films.
    ACS applied materials & interfaces, 2021, Dec-01, Volume: 13, Issue:47

    Topics: Adenine; Coated Materials, Biocompatible; Humans; Irinotecan; Microscopy, Atomic Force; Molecular Structure; Nanoparticles; Organophosphonates; Particle Size; Surface Properties; X-Ray Diffraction

2021