irinotecan has been researched along with mercaptopurine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Innocenti, F; Iyer, L; Ratain, MJ | 1 |
| McLeod, HL; Watters, JW | 1 |
| Maitland, ML; Ratain, MJ; Vasisht, K | 1 |
| Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kobayashi, H; Mano, H; Tsunoda, S | 1 |
| Burke, W; Haga, SB; Thummel, KE | 1 |
| Saito, Y; Sawada, J | 1 |
| Arndt, GM; Cheung, L; Failes, TW; Fletcher, JI; Neiron, Z; Yu, DM | 1 |
| Ise, Y; Kitagawa, C; Saka, H | 1 |
6 review(s) available for irinotecan and mercaptopurine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacogenetics: a tool for individualizing antineoplastic therapy.
Topics: Adenine; Antineoplastic Agents; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Imides; Irinotecan; Isoquinolines; Mercaptopurine; Methyltransferases; Naphthalimides; Organophosphonates; Oxidoreductases; Pharmacogenetics; Phenotype | 2000 |
Cancer pharmacogenomics: current and future applications.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Disease Models, Animal; DNA Adducts; DNA Repair; Fluorouracil; Glucuronosyltransferase; Glutathione Transferase; Humans; Irinotecan; Mercaptopurine; Methyltransferases; Neoplasms; Organoplatinum Compounds; Oxidoreductases; Pharmacogenetics; Polymorphism, Genetic; Thymidylate Synthase | 2003 |
TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy?
Topics: Camptothecin; Dihydrouracil Dehydrogenase (NADP); Genotype; Glucuronosyltransferase; Humans; Irinotecan; Mercaptopurine; Methyltransferases; Neoplasms; Pharmacogenetics; Treatment Outcome | 2006 |
Adding pharmacogenetics information to drug labels: lessons learned.
Topics: Antineoplastic Agents; Camptothecin; Drug Labeling; Genetic Variation; Glucuronosyltransferase; Humans; Irinotecan; Mercaptopurine; Methyltransferases; Pharmacogenetics; United States; United States Food and Drug Administration | 2006 |
[Prediction of adverse drug reactions based on genomic information].
Topics: Anti-Infective Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Arylamine N-Acetyltransferase; Asian People; Azathioprine; Camptothecin; Cytidine Deaminase; Deoxycytidine; Forecasting; Gemcitabine; Glucuronosyltransferase; Humans; Irinotecan; Mercaptopurine; Methyltransferases; Polymorphism, Genetic; Prodrugs; Sulfamethoxazole | 2007 |
8 other study(ies) available for irinotecan and mercaptopurine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Cytarabine; Depsipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Imatinib Mesylate; Irinotecan; K562 Cells; Leukemia; Lymphoma; Mercaptopurine; Piperazines; Pyrimidines; Time Factors | 2007 |
Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen.
Topics: Camptothecin; Dose-Response Relationship, Drug; Drug Approval; HEK293 Cells; High-Throughput Screening Assays; Humans; Irinotecan; Luciferases; Luminescent Measurements; Mercaptopurine; Multidrug Resistance-Associated Proteins; Small Molecule Libraries; United States | 2015 |
[Biomarkers for the prediction of adverse events].
Topics: Antineoplastic Agents; Biomarkers; Camptothecin; Fluorouracil; Humans; Irinotecan; Mercaptopurine; Tamoxifen | 2015 |