Page last updated: 2024-08-24

irinotecan and lomeguatrib

irinotecan has been researched along with lomeguatrib in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Middleton, MR; Sabharwal, A1
Brady, J; Corrie, PG; Margison, GP; Middleton, MR; Midgley, RS; Mortimer, P; Palmer, C; Sabharwal, A; Watson, AJ1

Reviews

1 review(s) available for irinotecan and lomeguatrib

ArticleYear
Exploiting the role of O6-methylguanine-DNA-methyltransferase (MGMT) in cancer therapy.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Dacarbazine; DNA Adducts; DNA Methylation; DNA Topoisomerases, Type I; Drug Administration Schedule; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Guanine; Humans; Irinotecan; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Organoplatinum Compounds; Prognosis; Promoter Regions, Genetic; Temozolomide; Topoisomerase I Inhibitors

2006

Trials

1 trial(s) available for irinotecan and lomeguatrib

ArticleYear
A phase I trial of lomeguatrib and irinotecan in metastatic colorectal cancer.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; O(6)-Methylguanine-DNA Methyltransferase; Purines; Treatment Outcome

2010