irinotecan has been researched along with folic acid in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 12 (50.00) | 24.3611 |
| 2020's | 6 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Adler, G; Lutz, MP | 1 |
| Höffken, K; Kliche, KO; Kubsch, K; Masri-Zada, R; Raida, M | 1 |
| Curley, SA; Ellis, LM; Gentner, B; Parikh, AA; Vauthey, JN; Wu, TT | 1 |
| Baba, E; Fujishima, H; Harada, M; Kikuchi, I; Mitsugi, K; Miyanaga, O; Nakano, S; Ueda, A | 1 |
| Assenat, E; Duffour, J; Ychou, M | 1 |
| Caca, K; Feisthammel, J; Mössner, J; Schoppmeyer, K; Schulze, M; Wiedmann, M | 1 |
| Atyabi, F; Azizi, E; Dinarvand, R; Ebrahimnejad, P; Jaafari, MR; Nomani, AR; Rad-Malekshahi, M; Sajadi, A | 1 |
| Atyabi, F; Dinarvand, R; Ebrahimnejad, P; Jafari, MR; Tabasi, SA | 1 |
| Yao, J; Zhang, Z | 1 |
| Besznyák, I; Bursics, A; Dede, K; Fekete, A; Kőszegi, G; Láng, I; Mersich, T; Mester, G; Pörneczi, B | 1 |
| Bloomfield, A; Dorton, R; Guan, J; Leamon, CP; Nelson, M; Reddy, JA; Vetzel, M | 1 |
| Choi, HG; Choi, Y; Jeong, JH; Kim, JO; Thapa, RK; Yong, CS; Youn, YS | 1 |
| Abdulla, A; Bagust, A; Beale, S; Boland, A; Fleeman, N; Kotas, E; McEntee, J; Palmer, D; Richardson, M; Stainthorpe, A | 1 |
| Decker, T; Denzlinger, C; Fischer von Weikersthal, L; Freiberg-Richter, J; Giessen-Jung, C; Graeven, U; Heinemann, V; Held, S; Jung, A; Kirchner, T; Modest, DP; Peuser, B; Peveling Genannt Reddemann, C; Schenk, M; Schuch, G; Schwaner, I; Stahler, A; Stintzing, S; Uhlig, J; Vehling-Kaiser, U | 1 |
| Christy-Bittel, J; Ciardiello, F; Cuyle, PJ; Desai, J; Elez, E; Fakih, M; Gollerkeri, A; Grothey, A; Huijberts, S; Kopetz, S; Maharry, K; Montagut, C; Peeters, M; Sandor, V; Schellens, JHM; Tabernero, J; Van Cutsem, E; Wasan, H; Yaeger, R; Yoshino, T | 1 |
| Jain, SK; Rajpoot, K | 1 |
| Cong, Z; Lam, KS; Liao, YH; Ma, SQ; Yang, FF; Zhang, L | 1 |
| Chakravarti, S; Das, RP; Gota, V; Gurjar, M; Kunwar, A; Lakhamje, P; Patel, SS; Singh, BG | 1 |
| de Gramont, A; Glimelius, B; Marshall, J; Stintzing, S; Yoshino, T | 1 |
| Branco de Barros, AL; Cassali, GD; de Aguiar Ferreira, C; de Alcântara Lemos, J; de Oliveira Silva, J; Fernandes, RS; Miranda, SEM; Nunes, SS; Oliveira, MC; Townsend, DM | 1 |
| Hu, Z; Huang, H; Huang, X; Wang, W; Wei, Z; Yan, R; Yang, D; Zhang, X; Zhang, Y | 1 |
| Berger, D; Brezoiu, AM; Matei, C; Miclea, LC; Mihailescu, M; Mitran, RA; Moisescu, MG; Sandu, AM; Savopol, T; Tarba, N | 1 |
5 review(s) available for irinotecan and folic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Chemotherapy of colorectal carcinoma].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Folic Acid; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Survival Analysis; Treatment Outcome | 2001 |
[Irinotecan for the treatment of metastatic colorectal cancer].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Humans; Irinotecan; Maximum Tolerated Dose; Multicenter Studies as Topic; Pharmacogenetics | 2006 |
Pegylated Liposomal Irinotecan Hydrochloride Trihydrate for Treating Pancreatic Cancer After Gemcitabine: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cost-Benefit Analysis; Fluorouracil; Folic Acid; Humans; Irinotecan; Leucovorin; Pancreatic Neoplasms; Technology Assessment, Biomedical; Topoisomerase I Inhibitors | 2018 |
Metastatic colorectal cancer: Advances in the folate-fluoropyrimidine chemotherapy backbone.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Fluorouracil; Folic Acid; Humans; Irinotecan; Leucovorin; Oxaliplatin; Prognosis | 2021 |
5 trial(s) available for irinotecan and folic acid
| Article | Year |
|---|---|
Chronomodulated chemotherapy in metastatic gastrointestinal cancer combining 5-FU and sodium folinate with oxaliplatin, irinotecan or gemcitabine: the Jena experience in 79 patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Stomach Neoplasms | 2002 |
Phase I study of CPT-11 and bolus 5-FU/ l-leucovorin in patients with metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Treatment Outcome | 2004 |
Irinotecan with 5-FU/FA in advanced biliary tract adenocarcinomas: a multicenter phase II trial.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Biliary Tract Neoplasms; Camptothecin; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Male; Middle Aged; Survival Analysis; Vitamin B Complex | 2007 |
Sequential Versus Combination Therapy of Metastatic Colorectal Cancer Using Fluoropyrimidines, Irinotecan, and Bevacizumab: A Randomized, Controlled Study-XELAVIRI (AIO KRK0110).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Leucovorin; Male | 2019 |
Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carbamates; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Male; Middle Aged; Mutation; Progression-Free Survival; Proto-Oncogene Proteins B-raf; Sulfonamides; Survival Rate | 2019 |
14 other study(ies) available for irinotecan and folic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Colonic Neoplasms; Female; Fluorouracil; Folic Acid; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Postoperative Complications; Retrospective Studies | 2003 |
Preparation and in vitro evaluation of actively targetable nanoparticles for SN-38 delivery against HT-29 cell lines.
Topics: Buffers; Camptothecin; Cell Death; Drug Delivery Systems; Folic Acid; HT29 Cells; Humans; Irinotecan; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Characterization, blood profile and biodistribution properties of surface modified PLGA nanoparticles of SN-38.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Drug Carriers; Folic Acid; Injections, Intravenous; Irinotecan; Lactic Acid; Molecular Structure; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Surface Properties; Tissue Distribution | 2011 |
Preparation of irinotecan-loaded folate-targeted liposome for tumor targeting delivery and its antitumor activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Delivery Systems; Folic Acid; Irinotecan; Liposomes; Mice; Mice, Inbred ICR; Random Allocation; Rats; Xenograft Model Antitumor Assays | 2012 |
[Preoperative chemotherapy in the surgical treatment of colorectal liver metastases].
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Hepatectomy; Hospitals, General; Humans; Irinotecan; Kaplan-Meier Estimate; Length of Stay; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Operative Time; Organoplatinum Compounds; Oxaliplatin; Surgery Department, Hospital; Treatment Outcome | 2013 |
Rational combination therapy of vintafolide (EC145) with commonly used chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Folic Acid; HeLa Cells; Humans; Irinotecan; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasms; Neoplasms, Experimental; Paclitaxel; Taxoids; Topotecan; Treatment Outcome; Vinca Alkaloids; Xenograft Model Antitumor Assays | 2014 |
Folate-Mediated Targeted Delivery of Combination Chemotherapeutics Loaded Reduced Graphene Oxide for Synergistic Chemo-Photothermal Therapy of Cancers.
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Drug Synergism; Female; Folic Acid; Graphite; Hep G2 Cells; Humans; Irinotecan; MCF-7 Cells; Nanoparticles; Particle Size; Phototherapy; Surface Properties; Taxoids | 2016 |
Irinotecan hydrochloride trihydrate loaded folic acid-tailored solid lipid nanoparticles for targeting colorectal cancer: development, characterization, and
Topics: Cell Survival; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Folic Acid; HT29 Cells; Humans; Irinotecan; Nanoparticles; Topoisomerase I Inhibitors | 2019 |
Size-Transformable Hyaluronan Stacked Self-Assembling Peptide Nanoparticles for Improved Transcellular Tumor Penetration and Photo-Chemo Combination Therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Disease Models, Animal; Dopamine; Female; Folic Acid; Hyaluronic Acid; Indocyanine Green; Injections, Intravenous; Irinotecan; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nanoparticles; Optical Imaging; Particle Size; Peptides; Rats; Rats, Wistar; Surface Properties | 2020 |
Tuning the pharmacokinetics and efficacy of irinotecan (IRI) loaded gelatin nanoparticles through folate conjugation.
Topics: A549 Cells; Animals; Drug Carriers; Female; Fibrosarcoma; Folate Receptors, GPI-Anchored; Folic Acid; Gelatin; Half-Life; HeLa Cells; Humans; Hydrogen-Ion Concentration; Irinotecan; Mice; Nanoparticles; Particle Size; Polysorbates; Topoisomerase I Inhibitors | 2020 |
pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment.
Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Folic Acid; Hydrogen-Ion Concentration; Irinotecan; Lipids; Liposomes; Mice, Inbred BALB C; Necrosis; Time Factors; Topoisomerase I Inhibitors; Tumor Burden | 2021 |
Folate Decorated Multifunctional Biodegradable Nanoparticles for Gastric Carcinoma Active Targeting Theranostics.
Topics: Carcinoma; Cell Line, Tumor; Drug Carriers; Folate Receptor 1; Folic Acid; Humans; Irinotecan; Nanoparticles; Particle Size; Polyethylene Glycols; Precision Medicine; Stomach Neoplasms; Tissue Distribution | 2022 |
Evaluation of intracellular distribution of folate functionalized silica nanoparticles using fluorescence and hyperspectral enhanced dark field microscopy.
Topics: Antineoplastic Agents; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Irinotecan; Microscopy; Nanoparticles; Porosity; Silicon Dioxide | 2022 |