Compounds > irinotecan
Page last updated: 2024-08-24

irinotecan and estrone

irinotecan has been researched along with estrone in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Imai, Y; Ishikawa, E; Sugimoto, Y; Tsukahara, S; Tsuruo, T1
Asada, S; Imai, Y; Ishikawa, E; Sugimoto, Y; Tsukahara, S; Yanase, K1
Minami, H; Nozawa, T; Sugiura, S; Tamai, I; Tsuji, A1
Iwamoto, T; Matsuda, H; Mizutani, H; Okuda, M; Ueno, Y1
Burckhardt, G; Flörl, S; Hagos, Y; Kühne, A; Marada, VV; Müller, J1
Finel, M; Ge, GB; Järvinen, E; Troberg, J; Yang, L1

Reviews

2 review(s) available for irinotecan and estrone

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for irinotecan and estrone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Estrone and 17beta-estradiol reverse breast cancer resistance protein-mediated multidrug resistance.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:3

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Estradiol; Estrone; Female; Flow Cytometry; Humans; Irinotecan; K562 Cells; Mitoxantrone; Neoplasm Proteins; Topoisomerase I Inhibitors; Topotecan; Transfection

2002
Gefitinib reverses breast cancer resistance protein-mediated drug resistance.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:9

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Camptothecin; Cell Line, Tumor; Drug Resistance, Neoplasm; Estrone; Gefitinib; Humans; Irinotecan; Neoplasm Proteins; Quinazolines; Topotecan

2004
Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line; Cells, Cultured; Estrone; Female; Glucuronides; Humans; Irinotecan; Liver; Liver-Specific Organic Anion Transporter 1; Oocytes; Polymorphism, Single Nucleotide; Topoisomerase I Inhibitors; Xenopus

2005
Involvement of specific transport system on uptake of lactone form of SN-38 in human intestinal epithelial cell line Caco-2.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:1

    Topics: Biological Transport; Caco-2 Cells; Camptotheca; Camptothecin; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Epithelial Cells; Estrone; Flavonoids; Humans; Intestinal Absorption; Intestinal Mucosa; Irinotecan; Lactones; Sulfobromophthalein; Taurocholic Acid

2012
Interaction of human organic anion transporter 2 (OAT2) and sodium taurocholate cotransporting polypeptide (NTCP) with antineoplastic drugs.
    Pharmacological research, 2015, Volume: 91

    Topics: Antineoplastic Agents; Apoptosis; Bendamustine Hydrochloride; Biological Transport; Camptothecin; Cyclic GMP; Estrone; HEK293 Cells; Humans; Irinotecan; Nitrogen Mustard Compounds; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Paclitaxel; Symporters

2015
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
    Molecular pharmaceutics, 2017, 09-05, Volume: 14, Issue:9

    Topics: Animals; Blotting, Western; Camptothecin; Chromatography, High Pressure Liquid; Coumarins; Diclofenac; Estradiol; Estrone; Flavonoids; Glucuronosyltransferase; Humans; Hymecromone; Intestinal Mucosa; Irinotecan; Kinetics; Microsomes, Liver

2017