Page last updated: 2024-08-24

irinotecan and d-alpha tocopherol

irinotecan has been researched along with d-alpha tocopherol in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	8 (88.89)	24.3611
2020's	1 (11.11)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Drozda, R; Grzegorczyk, K; Kontek, R; Sliwiński, M	1
Anderson, K; Burris, HA; Jones, S; Marier, JF; Pheng, L; Porubek, D; Trinh, MM; Warner, S	1
Ding, LY; Guo, M; Liu, YQ; Lu, Y; Ron, WT; Song, FF; Wang, Y; Yu, SQ	1
Jakubczak, M; Kontek, R; Matlawska-Wasowska, K	1
Hou, J; Lu, Y; Qi, SS; Rong, WT; Wang, DF; Xiao, Q; Xu, Q; You, J; Yu, SQ; Zhang, J	1
Adamo, RF; Alferiev, IS; Brodeur, GM; Chorny, M; Croucher, JL; Fishbein, I; Iyer, R; Kolla, V; Levy, RJ; Mangino, JL; Zhang, K	1
Hu, Y; Ismail, M; Li, B; Ling, L; Shang, Z	1

Reviews

1 review(s) available for irinotecan and d-alpha tocopherol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for irinotecan and d-alpha tocopherol

Article	Year
Pharmacokinetics of SN2310, an injectable emulsion that incorporates a new derivative of SN-38 in patients with advanced solid tumors. Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:10 Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Chemistry, Pharmaceutical; Emulsions; Female; Half-Life; Humans; Infusions, Intravenous; Irinotecan; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Middle Aged; Neoplasms; Neutropenia; Succinates; Technology, Pharmaceutical; Vitamin E	2011

Article

Year

Pharmacokinetics of SN2310, an injectable emulsion that incorporates a new derivative of SN-38 in patients with advanced solid tumors.

Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:10

Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Chemistry, Pharmaceutical; Emulsions; Female; Half-Life; Humans; Infusions, Intravenous; Irinotecan; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Middle Aged; Neoplasms; Neutropenia; Succinates; Technology, Pharmaceutical; Vitamin E

2011

Other Studies

7 other study(ies) available for irinotecan and d-alpha tocopherol

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Genotoxicity of irinotecan and its modulation by vitamins A, C and E in human lymphocytes from healthy individuals and cancer patients. Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:2 Topics: Adult; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camptothecin; Comet Assay; DNA Damage; DNA Repair; Female; Humans; Irinotecan; Lymphocytes; Male; Middle Aged; Mutagens; Vitamin A; Vitamin E	2010
Alpha-tocopheryl polyethylene glycol succinate-emulsified poly(lactic-co-glycolic acid) nanoparticles for reversal of multidrug resistance in vitro. Nanotechnology, 2012, Dec-14, Volume: 23, Issue:49 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Emulsions; Humans; Irinotecan; Lactic Acid; Materials Testing; Nanocapsules; Nanoparticles; Neoplasms, Experimental; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E	2012
The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro. Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Camptothecin; Cell Line, Tumor; Coloring Agents; Flow Cytometry; HT29 Cells; Humans; In Situ Nick-End Labeling; Irinotecan; Melatonin; Necrosis; Vitamin A; Vitamin E	2014
TPGS2k/PLGA nanoparticles for overcoming multidrug resistance by interfering mitochondria of human alveolar adenocarcinoma cells. ACS applied materials & interfaces, 2015, Feb-25, Volume: 7, Issue:7 Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Irinotecan; Lactic Acid; Mitochondria; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E	2015
Nanoparticle-mediated delivery of a rapidly activatable prodrug of SN-38 for neuroblastoma therapy. Biomaterials, 2015, Volume: 51 Topics: alpha-Tocopherol; Animals; Camptothecin; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Humans; Irinotecan; Mice, Nude; Nanoparticles; Neuroblastoma; Particle Size; Prodrugs; Treatment Outcome	2015
Vitamin E-based prodrug self-delivery for nanoformulated irinotecan with synergistic antitumor therapeutics. International journal of pharmaceutics, 2020, Mar-15, Volume: 577 Topics: A549 Cells; alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Drug Delivery Systems; Drug Liberation; Drug Stability; Drug Synergism; Female; Humans; Inhibitory Concentration 50; Irinotecan; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Prodrugs; Xenograft Model Antitumor Assays	2020