irinotecan has been researched along with curcumin in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (57.14) | 24.3611 |
| 2020's | 9 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, S; Li, K; Li, Z; Liang, W; Qiao, X; Song, W; Tang, S; Wang, Q; Wang, Y; Ye, M; Yu, S; Zhou, D | 1 |
| Cui, Z; Ji, S; Kuang, Y; Li, K; Lin, Y; Qiao, X; Song, W; Tang, S; Ye, M; Yu, S | 1 |
| Chen, XW; Ju, YL; Ou Yang, MZ; Wang, JZ; Zhang, WJ; Zhu, DJ | 1 |
| Uwagawa, T; Yanaga, K | 1 |
| Chen, QK; Chen, XW; Huang, YF; Liao, NZ; Liu, CC; Luo, ZT; Wang, GX; Zhang, WJ; Zhu, DJ | 1 |
| Chen, D; Jin, R; Kang, Y; Li, W; Liang, G; Qiu, P; Wang, J; Wu, J; Xu, Q; Zhang, S; Zhou, P; Zhou, Y; Zhu, M | 1 |
| Ambudkar, SV; Chufan, EE; Fukuda, M; Ishida, M; Iwabuchi, Y; Kanehara, K; Kudoh, K; Murakami, M; Naitoh, T; Ohnuma, S; Shibata, H; Sugisawa, N; Unno, M | 1 |
| Fei, Z; Li, G; Li, W; Wang, H; Xu, Y; Yan, H; Zhang, C | 1 |
| Ciftci, O; Taslıdere, A; Turkmen, NB | 1 |
| Chen, X; Ju, Y; Su, P; Wang, G; Yang, Y | 1 |
| Lu, Y; Luo, Z; Ouyang, M; Wu, J; Yao, X; Zhang, W; Zhu, D | 1 |
| Chen, X; Han, W; Li, Y; Shi, L; Wan, J; Wang, H; Xie, B | 1 |
| Sedlařík, V; Xiao, H | 1 |
| Guo, L; Guo, Y; Liu, F; Liu, H; Liu, Y; Xiao, H; Yuan, M | 1 |
| Chen, CC; Chen, CY; Cheng, SF; Chern, CY; Chi, YC; Chiu, YC; Kuo, YT; Lee, WC; Li, YC; Lin, PY; Liou, SJ; Tseng, ST; Tseng, WC; Wang, CA | 1 |
| Abugomaa, A; Ayame, H; Elbadawy, M; Hayashi, K; Hayashi, SM; Hazama, S; Ishihara, Y; Kaneda, M; Nagano, H; Nakajima, M; Sasaki, K; Shibutani, M; Shinohara, Y; Suzuki, N; Takenouchi, H; Tsunedomi, R; Usui, T; Yamawaki, H | 1 |
| Aydın, M; Başak, N; Çetin, A; Çiftci, O; Gökhan Turtay, M; Gürbüz, Ş; Oğuztürk, H; Uyanık, Ö; Yücel, N | 1 |
| Asher, GN; Dumond, J; Fallon, JK; Gbolahan, OB; Ivanova, A; McRee, AJ; Moore, DT; O'Neil, BH; Sanoff, HK; Smith, PC | 1 |
| Bhatti, G; Moffitt, MG; Silverman, L; Wulff, JE | 1 |
| Fang, Z; Gao, F; Peng, L; Peng, W; Song, F; Zhu, C | 1 |
| Brockmueller, A; Büsselberg, D; Kubatka, P; Mazurakova, A; Samuel, SM; Shakibaei, M | 1 |
2 review(s) available for irinotecan and curcumin
| Article | Year |
|---|---|
Effect of NF-κB inhibition on chemoresistance in biliary-pancreatic cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Biliary Tract Neoplasms; Bortezomib; Camptothecin; Curcumin; Deoxycytidine; Ditiocarb; Drug Resistance, Neoplasm; Gemcitabine; Guanidines; Humans; Irinotecan; Molecular Targeted Therapy; NF-kappa B; Paclitaxel; Pancreatic Neoplasms; Pregnenediones; Treatment Outcome | 2015 |
Curcumin, calebin A and chemosensitization: How are they linked to colorectal cancer?
Topics: Cell Line, Tumor; Cisplatin; Colorectal Neoplasms; Curcumin; Cytostatic Agents; Drug Resistance, Neoplasm; Fluorouracil; Humans; Irinotecan; Oxaliplatin | 2023 |
1 trial(s) available for irinotecan and curcumin
| Article | Year |
|---|---|
A phase I evaluation of the effect of curcumin on dose-limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumors.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Curcumin; Humans; Irinotecan; Maximum Tolerated Dose; Neoplasms | 2022 |
18 other study(ies) available for irinotecan and curcumin
| Article | Year |
|---|---|
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.
Topics: Acetylcholinesterase; Animals; Carbon Tetrachloride; Drugs, Chinese Herbal; Glycyrrhiza; Glycyrrhiza uralensis; GPI-Linked Proteins; Hep G2 Cells; Humans; Influenza A Virus, H1N1 Subtype; Lipopolysaccharides; Liver; Macrophages; MCF-7 Cells; Medicine, Traditional; Mice; Molecular Structure; Monophenol Monooxygenase; NF-kappa B; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Pyrrolizidine Alkaloids; Rhizome; Structure-Activity Relationship | 2016 |
Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
Topics: Animals; Antioxidants; Drug Screening Assays, Antitumor; Glycyrrhiza; Hep G2 Cells; Humans; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Monophenol Monooxygenase; NF-kappa B; Nitric Oxide; Phenols; Plant Roots; Plants, Medicinal; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rhizome | 2017 |
Proteomic analysis identifies proteins associated with curcumin-enhancing efficacy of irinotecan-induced apoptosis of colorectal cancer LOVO cell.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Curcumin; Humans; Irinotecan; Proteomics; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Curcumin; Drug Synergism; Drug Therapy, Combination; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Irinotecan; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Transcription Factor CHOP | 2017 |
Synthesis and evaluation of asymmetric curcuminoid analogs as potential anticancer agents that downregulate NF-κB activation and enhance the sensitivity of gastric cancer cell lines to irinotecan chemotherapy.
Topics: Antineoplastic Agents; Camptothecin; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; Humans; Irinotecan; Molecular Structure; NF-kappa B; Stomach Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured | 2017 |
Synthetic Analogs of Curcumin Modulate the Function of Multidrug Resistance-Linked ATP-Binding Cassette Transporter ABCG2.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Azides; Benzene Derivatives; Biological Availability; Biological Transport; Camptothecin; Cell Line, Tumor; Curcumin; Drug Resistance, Neoplasm; Drug Synergism; Flow Cytometry; Humans; Irinotecan; Ketones; Mitoxantrone; Neoplasm Proteins; Prazosin | 2017 |
Curcumin reverses irinotecan resistance in colon cancer cell by regulation of epithelial-mesenchymal transition.
Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Curcumin; Drug Interactions; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Humans; Irinotecan; Vimentin | 2018 |
Curcumin protects heart tissue against irinotecan-induced damage in terms of cytokine level alterations, oxidative stress, and histological damage in rats.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Camptothecin; Cardiotonic Agents; Cardiotoxicity; Curcumin; Cytokines; Irinotecan; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2018 |
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Curcumin; Drug Resistance, Neoplasm; Humans; Irinotecan; Neoplastic Stem Cells; Spheroids, Cellular | 2018 |
Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Cell Line; Colorectal Neoplasms; Curcumin; Diarrhea; Disease Models, Animal; Drug Evaluation, Preclinical; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Epithelial Cells; Humans; Injections, Intraperitoneal; Intestinal Mucosa; Irinotecan; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Oxidative Stress; Rats; Signal Transduction; Topoisomerase I Inhibitors; Treatment Outcome | 2019 |
Orally Deliverable Nanotherapeutics for the Synergistic Treatment of Colitis-Associated Colorectal Cancer.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colitis; Colorectal Neoplasms; Curcumin; Cytokines; Dextran Sulfate; Disease Models, Animal; Disease Progression; Drug Synergism; Female; Inflammation; Inflammation Mediators; Intestines; Irinotecan; Macrophages; Mice; Mice, Inbred C57BL; Nanoparticles; RAW 264.7 Cells | 2019 |
A Rapid and Sensitive HPLC Method for Simultaneous Determination of Irinotecan Hydrochloride and Curcumin in Co-delivered Polymeric Nanoparticles.
Topics: Chromatography, High Pressure Liquid; Curcumin; Drug Delivery Systems; Irinotecan; Limit of Detection; Linear Models; Nanoparticles; Polyesters; Polyethylene Glycols; Reproducibility of Results | 2020 |
Self-Monitoring and Self-Delivery of Self-Assembled Fluorescent Nanoparticles in Cancer Therapy.
Topics: Animals; Apoptosis; Cell Cycle; Cell Death; Cell Line, Tumor; Curcumin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Endocytosis; Fluorescence; Humans; Imaging, Three-Dimensional; Irinotecan; Nanoparticles; Neoplasms; Particle Size; Zebrafish | 2021 |
Targeting HR Repair as a Synthetic Lethal Approach to Increase DNA Damage Sensitivity by a RAD52 Inhibitor in BRCA2-Deficient Cancer Cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; BRCA2 Protein; Breast Neoplasms; Cell Proliferation; Curcumin; DNA Damage; DNA Repair; Female; Gene Expression Regulation, Neoplastic; Homologous Recombination; Humans; Irinotecan; Mice; Mice, Nude; Mutation; Rad52 DNA Repair and Recombination Protein; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Cycle; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Curcumin; Drug Synergism; Fluorouracil; Humans; Irinotecan; Male; Mice, SCID; Neoplastic Stem Cells; Organoids; Oxaliplatin | 2021 |
Curcumin protects against testis-specific side effects of irinotecan.
Topics: Animals; Curcumin; Irinotecan; Male; Protective Agents; Rats; Rats, Sprague-Dawley; Testis; Thiobarbituric Acid Reactive Substances; Topoisomerase I Inhibitors | 2021 |
Improvements in Drug-Delivery Properties by Co-Encapsulating Curcumin in SN-38-Loaded Anticancer Polymeric Nanoparticles.
Topics: Curcumin; Drug Carriers; Drug Delivery Systems; Irinotecan; Micelles; Nanoparticles; Particle Size; Polyethylene Glycols; Polymers | 2022 |
Curcumin Suppresses the Progression of Colorectal Cancer by Improving Immunogenic Cell Death Caused by Irinotecan.
Topics: Animals; Colonic Neoplasms; Curcumin; HMGB1 Protein; Immunogenic Cell Death; Irinotecan; Mice | 2022 |