Page last updated: 2024-08-24

irinotecan and baicalin

irinotecan has been researched along with baicalin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Hagiwara, T; Hirohashi, M; Kakihata, K; Kasai, Y; Kitano, Y; Kobayashi, R; Mori, K; Nagai, E; Nomura, M; Takasuna, K1
Hirano, T; Iseki, K; Itagaki, S; Itoh, T; Sumi, Y; Takemoto, I1
Hagiwara, T; Kamataki, T; Kumazawa, E; Nagai, E; Onose, S; Takasuna, K; Watanabe, K; Yoshida, S1
Itoh, T1
Iwamoto, T; Matsuda, H; Mizutani, H; Okuda, M; Ueno, Y1
Fujita, D; Nakanishi, T; Saito, Y; Tamai, I1

Reviews

1 review(s) available for irinotecan and baicalin

ArticleYear
[Pharmacokinetic study of cancer chemotherapy].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2006, Volume: 126, Issue:9

    Topics: Animals; Antineoplastic Agents; Biological Transport; Caco-2 Cells; Camptothecin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Flavonoids; Glucuronides; Humans; Ileum; Irinotecan; Male; Rats; Rats, Wistar; Sulfobromophthalein

2006

Other Studies

7 other study(ies) available for irinotecan and baicalin

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Protective effects of kampo medicines and baicalin against intestinal toxicity of a new anticancer camptothecin derivative, irinotecan hydrochloride (CPT-11), in rats.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Atropine; Camptothecin; Cecum; Diarrhea; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; Glucuronidase; Intestines; Irinotecan; Male; Rats; Rats, Wistar

1995
Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Caco-2 Cells; Camptothecin; Coloring Agents; Enzyme Inhibitors; Flavonoids; Humans; Intestinal Mucosa; Intestines; Irinotecan; Sulfobromophthalein; Tumor Cells, Cultured

2005
Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:4

    Topics: Animals; Antidiarrheals; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Enzyme Inhibitors; Flavonoids; Glucuronidase; Intestines; Irinotecan; Male; Medicine, Kampo; Penicillins; Rats; Rats, Wistar; Streptomycin

2006
Involvement of specific transport system on uptake of lactone form of SN-38 in human intestinal epithelial cell line Caco-2.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:1

    Topics: Biological Transport; Caco-2 Cells; Camptotheca; Camptothecin; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Epithelial Cells; Estrone; Flavonoids; Humans; Intestinal Absorption; Intestinal Mucosa; Irinotecan; Lactones; Sulfobromophthalein; Taurocholic Acid

2012
Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Bacteria; Bacterial Proteins; Camptothecin; Cefixime; Diarrhea; Enzyme Inhibitors; Female; Flavonoids; Food-Drug Interactions; Fruit and Vegetable Juices; Gastrointestinal Microbiome; Gene Transfer Techniques; Glucuronidase; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestines; Irinotecan; Kinetics; Malus; Mice, Inbred C57BL; Oocytes; Organic Anion Transporters; Xenopus laevis

2016