irinotecan has been researched along with asoxime chloride in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A | 1 |
| Berend, S; Fuchs, N; Kopjar, N; Radić, B; Vrdoljak, AL; Zeljezić, D | 1 |
| Berend, S; Kopjar, N; Kuca, K; Mladinić, M; Piljac-Zegarac, J; Plestina, S; Radić, B; Vrdoljak, AL; Zeljezić, D | 1 |
3 other study(ies) available for irinotecan and asoxime chloride
| Article | Year |
|---|---|
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine | 2008 |
Evaluation of HI-6 oxime: potential use in protection of human acetylcholinesterase inhibited by antineoplastic drug irinotecan and its cyto/genotoxicity in vitro.
Topics: Acetylcholinesterase; Adult; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cells, Cultured; Cholinesterase Inhibitors; Chromosome Aberrations; Female; Humans; Irinotecan; Lymphocytes; Molecular Structure; Oximes; Pyridinium Compounds | 2007 |
Irinotecan side effects relieved by the use of HI-6 oxime: in vivo experimental approach.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Brain; Camptothecin; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; DNA Damage; Drug Interactions; Erythrocytes; Free Radical Scavengers; Irinotecan; Leukocytes; Lipid Peroxidation; Liver; Male; Mutagenicity Tests; Oximes; Pyridinium Compounds; Random Allocation; Rats; Rats, Wistar; Time Factors | 2009 |