Compounds > irinotecan
Page last updated: 2024-08-24

irinotecan and ascorbic acid

irinotecan has been researched along with ascorbic acid in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (88.89)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Drozda, R; Grzegorczyk, K; Kontek, R; Sliwiński, M1
Aigner, A; Czubayko, F; Frömberg, A; Gutsch, D; Schulze, D; Vollbracht, C; Weiss, G1
Jakubczak, M; Kontek, R; Matlawska-Wasowska, K1
Chen, DL; Chen, LZ; Chen, Y; Ju, HQ; Li, YH; Lu, JH; Lu, YX; Mo, HY; Ren, C; Sheng, H; Wang, DS; Wang, F; Wang, FH; Wang, Y; Wang, YN; Wang, ZX; Wu, QN; Xu, RH; Zeng, ZL1
Karamysheva, АF; Moiseeva, NI; Saakyan, SV; Tadevosyan, SS; Tsygankov, АY; Zhil'tsova, MG1
Goto, K; Hiramoto, K; Kondo, K; Ooi, K; Sano, R1
Buettner, GR; Carroll, RS; Cullen, JJ; Du, J; O'Leary, BR; Ruppenkamp, EK; Steers, GJ; Wagner, BA1

Reviews

1 review(s) available for irinotecan and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for irinotecan and ascorbic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Genotoxicity of irinotecan and its modulation by vitamins A, C and E in human lymphocytes from healthy individuals and cancer patients.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:2

    Topics: Adult; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camptothecin; Comet Assay; DNA Damage; DNA Repair; Female; Humans; Irinotecan; Lymphocytes; Male; Middle Aged; Mutagens; Vitamin A; Vitamin E

2010
Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Ascorbic Acid; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dehydroascorbic Acid; Docetaxel; Drug Synergism; Epirubicin; Humans; Irinotecan; Male; Organoplatinum Compounds; Oxaliplatin; Prostatic Neoplasms; Taxoids; Vinblastine; Vinorelbine

2011
The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Camptothecin; Cell Line, Tumor; Coloring Agents; Flow Cytometry; HT29 Cells; Humans; In Situ Nick-End Labeling; Irinotecan; Melatonin; Necrosis; Vitamin A; Vitamin E

2014
Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation.
    Theranostics, 2018, Volume: 8, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Glucose Transporter Type 1; Glutathione; Humans; Irinotecan; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Models, Biological; Oxaliplatin; Oxidation-Reduction; Oxidative Stress; Prognosis; Reactive Oxygen Species; Stomach Neoplasms; Treatment Outcome; Xenograft Model Antitumor Assays

2018
Retinoblastoma Cell Culturing and Evaluation of Their Drug Resistance.
    Bulletin of experimental biology and medicine, 2018, Volume: 165, Issue:1

    Topics: Antineoplastic Agents; Ascorbic Acid; Camptothecin; Cell Survival; Child; Child, Preschool; Drug Resistance, Neoplasm; Female; Humans; Ifosfamide; Infant; Irinotecan; Male; Organoplatinum Compounds; Oxaliplatin; Retinoblastoma; Tumor Cells, Cultured

2018
Administration of High-Dose Vitamin C and Irinotecan Ameliorates Colorectal Cancer Induced by Azoxymethane and Dextran Sodium Sulfate in Mice.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Azoxymethane; Colorectal Neoplasms; Dextran Sulfate; Dose-Response Relationship, Drug; Drug Synergism; Interleukin-6; Irinotecan; Male; Mice, Hairless; Reactive Oxygen Species

2018
Pharmacological Ascorbate Enhances Chemotherapies in Pancreatic Ductal Adenocarcinoma.
    Pancreas, 2022, 07-01, Volume: 51, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Carcinoma, Pancreatic Ductal; Fluorouracil; Humans; Irinotecan; Leucovorin; Mice; Oxaliplatin; Paclitaxel; Pancreatic Neoplasms

2022