irinotecan has been researched along with acetylcysteine in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bae, SY; Hong, JY; Jung, C; Kang, SS; Lee, SK; Park, HJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gleyzer, N; Scarpulla, RC | 1 |
| Ding, C; Gu, Y; Li, Z; Liu, B; Tang, W; Wang, Z; Yu, T; Zhang, C | 1 |
1 review(s) available for irinotecan and acetylcysteine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
6 other study(ies) available for irinotecan and acetylcysteine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; Checkpoint Kinase 1; Checkpoint Kinase 2; Colonic Neoplasms; Dioxins; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Mice; Mice, Nude; Molecular Structure; Phytolacca americana; Protein Kinases; Seeds; Signal Transduction; Tumor Suppressor Protein p53 | 2015 |
Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Camptothecin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cornified Envelope Proline-Rich Proteins; Gene Expression; Gene Knockdown Techniques; Histamine H1 Antagonists; Humans; Inflammation; Irinotecan; Kinetics; Meclizine; Oxidants; Oxidative Stress; Proto-Oncogene Proteins c-myc; Proton Ionophores; RNA, Small Interfering; Topoisomerase I Inhibitors; Transcription Factors; Transcriptional Activation; Vitamin K 3 | 2013 |
Hepatic ROS Mediated Macrophage Activation Is Responsible for Irinotecan Induced Liver Injury.
Topics: Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury, Chronic; Fatty Liver; Hepatocytes; Irinotecan; Macrophage Activation; Mice | 2022 |