irinotecan has been researched along with 4-nitrophenylphosphate in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atsumi, R; Hakusui, H; Hosokawa, M; Nagai, E; Satoh, T; Suzuki, W | 1 |
| Gao, J; Liu, D; Liu, Y; Ren, X; Xu, Y; Zhang, C | 1 |
2 other study(ies) available for irinotecan and 4-nitrophenylphosphate
| Article | Year |
|---|---|
Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1- piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Camptothecin; Carboxylic Ester Hydrolases; Cattle; Cricetinae; Dogs; Guinea Pigs; Haplorhini; Humans; Hydrolysis; Irinotecan; Isoenzymes; Kinetics; Mice; Microsomes, Liver; Nitrophenols; Organophosphorus Compounds; Rabbits; Rats; Species Specificity | 1994 |
Identification of carboxylesterases expressed in rat intestine and effects of their hydrolyzing activity in predicting first-pass metabolism of ester prodrugs.
Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Biotransformation; Blotting, Western; Camptothecin; Carboxylic Ester Hydrolases; Constitutive Androstane Receptor; Esters; Hydrolysis; Imidazolidines; Intestines; Irinotecan; Male; Nitrophenols; Organophosphorus Compounds; Parasympathomimetics; Pregnane X Receptor; Prodrugs; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger | 2011 |