irinotecan has been researched along with 4-nitrophenyl acetate in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mazzolari, A; Pedretti, A; Testa, B; Vistoli, G | 1 |
| Bugat, R; Canal, P; Chatelut, E; Guichard, S; Hennebelle, I; Terret, C | 1 |
| Band, R; Bowen, D; Cottrell, J; Grem, JL; Guemei, AA; Hehman, H; Ismail, AS; Pavlov, MV; Prudhomme, M; Takimoto, CH; Taylor, RE | 1 |
| Kim, SR; Kubo, T; Matsumoto, K; Minami, H; Nakajima, T; Ohno, Y; Ohtsu, A; Ozawa, S; Sai, K; Saijo, N; Saito, H; Saito, Y; Sawada, J; Shirao, K; Yamamoto, N; Yoshida, T | 1 |
| Furukubo, T; Hojo, A; Izumi, S; Katsube, Y; Koide, H; Minegaki, T; Nishiguchi, K; Ochiai, M; Shima, D; Tsujimoto, M; Yamakawa, T | 1 |
1 trial(s) available for irinotecan and 4-nitrophenyl acetate
| Article | Year |
|---|---|
Human plasma carboxylesterase and butyrylcholinesterase enzyme activity: correlations with SN-38 pharmacokinetics during a prolonged infusion of irinotecan.
Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Butyrylcholinesterase; Butyrylthiocholine; Camptothecin; Carboxylic Ester Hydrolases; Humans; Hydrolysis; Irinotecan; Nitrophenols; Predictive Value of Tests | 2001 |
4 other study(ies) available for irinotecan and 4-nitrophenyl acetate
| Article | Year |
|---|---|
In silico prediction of human carboxylesterase-1 (hCES1) metabolism combining docking analyses and MD simulations.
Topics: Carboxylic Ester Hydrolases; Catalytic Domain; Computer Simulation; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Substrate Specificity | 2010 |
Characterization of CPT-11 converting carboxylesterase activity in colon tumor and normal tissues: comparison with p-nitro-phenylacetate converting carboxylesterase activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylic Ester Hydrolases; Colon; Colonic Neoplasms; DNA Topoisomerases, Type I; Enzyme Activation; Enzyme Inhibitors; Humans; Irinotecan; Kinetics; Liver; Nitrophenols; Rats; Substrate Specificity; Topoisomerase I Inhibitors | 2000 |
Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2).
Topics: Animals; Asian People; Camptothecin; Carboxylesterase; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Humans; Irinotecan; Nitrophenols; Polymorphism, Single Nucleotide; RNA Splicing; Umbelliferones | 2005 |
Acceleration of carboxylesterase-mediated activation of irinotecan to SN-38 by serum from patients with end-stage kidney disease.
Topics: Carboxylesterase; Case-Control Studies; Fatty Acids; Humans; Irinotecan; Kidney Failure, Chronic; Microsomes, Liver; Nitrophenols; Topoisomerase I Inhibitors; Uremia | 2018 |