irinotecan has been researched along with 10,11-methylenedioxy-20-camptothecin in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, X; Jiang, T; Li, J; Qi, X; Wu, G; Yin, R; Yu, R; Zhang, G | 1 |
| Mangold, G; Manikumar, G; Marty, J; Potter, PM; Vladu, B; Von Hoff, DD; Wadkins, RM; Wall, ME; Wani, MC; Weitman, S | 1 |
| Collins, JR; Jerina, DM; Kroth, H; Laco, GS; Luke, BT; Pommier, Y; Sayer, JM | 1 |
3 other study(ies) available for irinotecan and 10,11-methylenedioxy-20-camptothecin
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of novel 7-substituted 10,11-methylenedioxy-camptothecin derivatives against drug-resistant small-cell lung cancer in vitro and in vivo.
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Humans; Irinotecan; Lung Neoplasms; Small Cell Lung Carcinoma | 2022 |
Water soluble 20(S)-glycinate esters of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cholinesterase Inhibitors; Drug Screening Assays, Antitumor; Esters; Female; Glycine; Humans; Infant, Newborn; Irinotecan; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Human topoisomerase I inhibition: docking camptothecin and derivatives into a structure-based active site model.
Topics: Binding Sites; Binding, Competitive; Camptothecin; DNA; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Hydrogen Bonding; Irinotecan; Models, Molecular; Molecular Conformation; Nucleic Acid Heteroduplexes; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Topoisomerase I Inhibitors | 2002 |