iridoids and succinic-anhydride

iridoids has been researched along with succinic-anhydride* in 1 studies

Other Studies

1 other study(ies) available for iridoids and succinic-anhydride

Article	Year
Analysis of gelatin plasma substitutes in blood based on detection of hydroxyproline derivatives. Artificial cells, blood substitutes, and immobilization biotechnology, 2011, Volume: 39, Issue:1 The gelatin plasma substitute is often polydisperse and heterogenous, making it difficult to determine the elimination rate and half-life in the body. In this study, one method was developed based on quantitative determination of hydroxyproline derivatives. Two plasma substitutes were prepared by succinylation and genipin-crosslinking, respectively. After transfusion, the blood samples were hydrolyzed and derivatized, and then analyzed by HPLC. A two-phase exponential association equation was used for fitting the time-concentration curves. The results indicated that this method could be used for quantitative determination of gelatin in blood, and the pharmacokinetic parameters such as elimination rate and half-life. Topics: Animals; Blood Vessels; Blood Volume; Cattle; Cross-Linking Reagents; Dinitrofluorobenzene; Gelatin; Half-Life; Hemorrhage; Hydrolysis; Hydroxyproline; Iridoid Glycosides; Iridoids; Male; Plasma Substitutes; Rabbits; Succinic Anhydrides	2011

Article

Year

Analysis of gelatin plasma substitutes in blood based on detection of hydroxyproline derivatives.

Artificial cells, blood substitutes, and immobilization biotechnology, 2011, Volume: 39, Issue:1

The gelatin plasma substitute is often polydisperse and heterogenous, making it difficult to determine the elimination rate and half-life in the body. In this study, one method was developed based on quantitative determination of hydroxyproline derivatives. Two plasma substitutes were prepared by succinylation and genipin-crosslinking, respectively. After transfusion, the blood samples were hydrolyzed and derivatized, and then analyzed by HPLC. A two-phase exponential association equation was used for fitting the time-concentration curves. The results indicated that this method could be used for quantitative determination of gelatin in blood, and the pharmacokinetic parameters such as elimination rate and half-life.

Topics: Animals; Blood Vessels; Blood Volume; Cattle; Cross-Linking Reagents; Dinitrofluorobenzene; Gelatin; Half-Life; Hemorrhage; Hydrolysis; Hydroxyproline; Iridoid Glycosides; Iridoids; Male; Plasma Substitutes; Rabbits; Succinic Anhydrides

2011