iridoids has been researched along with pristane* in 2 studies
2 other study(ies) available for iridoids and pristane
| Article | Year |
|---|---|
Dietary oleuropein and its acyl derivative ameliorate inflammatory response in peritoneal macrophages from pristane-induced SLE mice via canonical and noncanonical NLRP3 inflammasomes pathway.
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease without an effective and safe treatment. Besides, macrophages are the major components of the innate immune system and play a critical role in the inflammation process in SLE. Secoiridoids from olive tree are phenolic compounds which have shown important pharmacological effects. Particularly, oleuropein (OL) has shown antioxidant, anti-inflammatory and immunomodulatory properties suggesting a potential application in a large number of inflammatory and reactive oxygen species (ROS)-mediated diseases. In addition, different studies have shown the importance of acyl derivatives of natural phenols due to their better hydrophilic/lipophilic balance. Topics: Animals; Anti-Inflammatory Agents; Cytokines; Inflammasomes; Iridoid Glucosides; Iridoids; Lupus Erythematosus, Systemic; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein; Olea; Phenols; Terpenes | 2020 |
Dietary oleuropein and its new acyl-derivate attenuate murine lupus nephritis through HO-1/Nrf2 activation and suppressing JAK/STAT, NF-κB, MAPK and NLRP3 inflammasome signaling pathways.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Heme Oxygenase-1; Inflammasomes; Iridoid Glucosides; Iridoids; Janus Kinases; Kidney; Lupus Nephritis; MAP Kinase Signaling System; Matrix Metalloproteinase 3; Membrane Proteins; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; NLR Family, Pyrin Domain-Containing 3 Protein; STAT Transcription Factors; Terpenes | 2019 |