iridoids and benzaldehyde

iridoids has been researched along with benzaldehyde* in 1 studies

Other Studies

1 other study(ies) available for iridoids and benzaldehyde

ArticleYear
Multicomponent Domino Reaction in the Asymmetric Synthesis of Cyclopentan[c]pyran Core of Iridoid Natural Products.
    Molecules (Basel, Switzerland), 2020, Mar-13, Volume: 25, Issue:6

    The asymmetric synthesis of a compound with the cyclopentan[c]pyran core of iridoid natural products in four steps and 40% overall yield is reported. Our methodology includes a one-pot tandem domino reaction which provides a trisubstituted cyclopentane with five new completely determined stereocenters, which were determined through 2D homo and heteronuclear NMR and n.O.e. experiments on different compounds specially designed for this purpose, such as a dioxane obtained from a diol. Due to their pharmaceutical properties, including sedative, analgesic, anti-inflammatory, CNS depressor or anti-conceptive effects, this methodology to produce the abovementioned iridoid derivatives, is an interesting strategy in terms of new drug discovery as well as pharmaceutical development.

    Topics: Benzaldehydes; Biological Products; Carbon-13 Magnetic Resonance Spectroscopy; Cyclopentanes; Iridoids; Oxidation-Reduction; Proton Magnetic Resonance Spectroscopy; Pyrans; Stereoisomerism

2020