ipsapirone has been researched along with clonidine in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coke, JA; McMillen, BA; Sanghera, MK; Williams, HL | 1 |
| Bianchi, G; Caccia, S; Della Vedova, F; Garattini, S | 1 |
| Fozard, JR; Ramage, AG | 1 |
| Geiger, G; Grimes, D; Heaslip, RJ; Henry, DE; Lee, DK; Rimele, TJ | 1 |
| Berlin, I; Cesselin, F; Chalon, S; Payan, C; Puech, AJ; Schöllnhammer, G; Varoquaux, O | 1 |
| Goodman, M; Grossman, R; Mitropoulou, V; New, A; Reynolds, D; Schmeidler, J; Siever, LJ; Silverman, J | 1 |
2 trial(s) available for ipsapirone and clonidine
| Article | Year |
|---|---|
Evaluation of the alpha 2-adrenoceptor blocking properties of buspirone and ipsapirone in healthy subjects. Relationship with the plasma concentration of the common metabolite 1-(2-pyrimidinyl)-piperazine.
Topics: Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Anti-Anxiety Agents; Blood Pressure; Body Temperature; Buspirone; C-Peptide; Clonidine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Growth Hormone; Heart Rate; Humans; Insulin; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pyrimidines; Serotonin Antagonists | 1995 |
Efficacy of open-label venlafaxine in subjects with major depressive disorder: associations with neuroendocrine response to serotonergic and noradrenergic probes.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antidepressive Agents, Second-Generation; Clonidine; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Norepinephrine; Personality Inventory; Pyrimidines; Serotonin; Serotonin Receptor Agonists; Treatment Outcome; Venlafaxine Hydrochloride | 2004 |
4 other study(ies) available for ipsapirone and clonidine
| Article | Year |
|---|---|
Ipsapirone and 1-(2-pyrimidinyl)-piperazine increase rat locus coeruleus noradrenergic activity.
Topics: Action Potentials; Animals; Brain; Buspirone; Clonidine; Dose-Response Relationship, Drug; Locus Coeruleus; Male; Norepinephrine; Pyrimidines; Rats; Rats, Inbred Strains | 1990 |
The alpha 2-adrenoceptor antagonist activity of ipsapirone and gepirone is mediated by their common metabolite 1-(2-pyrimidinyl)-piperazine (PmP).
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Buspirone; Chromatography, High Pressure Liquid; Clonidine; Drug Interactions; Gastrointestinal Transit; Injections, Intravenous; Male; Pyrimidines; Rats | 1988 |
Evidence that the putative 5-HT1A receptor agonists, 8-OH-DPAT and ipsapirone, have a central hypotensive action that differs from that of clonidine in anaesthetised cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Cats; Clonidine; Dioxanes; Heart Rate; Idazoxan; Male; Naphthalenes; Neurons; Pyrimidines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes; Trimethaphan; Vagotomy | 1987 |
Tissue-dependent alpha adrenoceptor activity of buspirone and related compounds.
Topics: Animals; Buspirone; Cerebral Cortex; Clonidine; Guinea Pigs; Male; Norepinephrine; Phenylephrine; Prazosin; Pyrimidines; Rabbits; Rats; Receptors, Adrenergic, alpha; Vas Deferens | 1987 |