iodotamoxifen and iodoantipyrine

iodotamoxifen has been researched along with iodoantipyrine* in 1 studies

Other Studies

1 other study(ies) available for iodotamoxifen and iodoantipyrine

Article	Year
Estrogen receptor-mediated cytotoxicity using iodine-125. Journal of cellular biochemistry, 1983, Volume: 21, Issue:1 Auger effects from 125I decay are singularly damaging if localized in DNA as the thymidine analogue 125I-iododeoxyuridine (125IUdR). Recent experience with steroid sex hormones extends these observations by demonstrating cytotoxicity in sites other than the DNA backbone. We have compared the cytotoxicity in human MCF-7 breast cancer cells of 125IUdR, 125I-iodotamoxifen, a nonsteroidal antiestrogen that is translocated from the cytoplasm to the nucleus of receptor containing cells, and 125I-iodoantipyrine, a biological indicator of the body water space. Cytotoxicity is critically dependent upon subcellular localization. Topics: Antipyrine; Breast Neoplasms; Cell Line; Cell Survival; Humans; Idoxuridine; Iodine Radioisotopes; Receptors, Estrogen; Tamoxifen	1983

Article

Year

Estrogen receptor-mediated cytotoxicity using iodine-125.

Journal of cellular biochemistry, 1983, Volume: 21, Issue:1

Auger effects from 125I decay are singularly damaging if localized in DNA as the thymidine analogue 125I-iododeoxyuridine (125IUdR). Recent experience with steroid sex hormones extends these observations by demonstrating cytotoxicity in sites other than the DNA backbone. We have compared the cytotoxicity in human MCF-7 breast cancer cells of 125IUdR, 125I-iodotamoxifen, a nonsteroidal antiestrogen that is translocated from the cytoplasm to the nucleus of receptor containing cells, and 125I-iodoantipyrine, a biological indicator of the body water space. Cytotoxicity is critically dependent upon subcellular localization.

Topics: Antipyrine; Breast Neoplasms; Cell Line; Cell Survival; Humans; Idoxuridine; Iodine Radioisotopes; Receptors, Estrogen; Tamoxifen

1983