iodoproxyfan has been researched along with thioperamide in 9 studies
| Studies (iodoproxyfan) | Trials (iodoproxyfan) | Recent Studies (post-2010) (iodoproxyfan) | Studies (thioperamide) | Trials (thioperamide) | Recent Studies (post-2010) (thioperamide) |
|---|---|---|---|---|---|
| 25 | 0 | 2 | 483 | 1 | 73 |
| Protein | Taxonomy | iodoproxyfan (IC50) | thioperamide (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 6.0954 | |
| Histamine H4 receptor | Homo sapiens (human) | 0.5666 | |
| Histamine H3 receptor | Homo sapiens (human) | 0.3072 | |
| Cholesterol 24-hydroxylase | Homo sapiens (human) | 0.43 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garbarg, M; Hüls, A; Ligneau, X; Purand, K; Schunack, W; Schwartz, JC; Stark, H | 1 |
| Arrang, JM; Ganellin, CR; Ligneau, X; Schunack, W; Schwartz, JC; Sippl, W; Stark, H | 1 |
| De Esch, IJ; Dean, PM; Hoffmann, M; Leurs, R; Menge, WM; Mills, JE; Nederkoorn, PH; Perkins, TD; Romeo, G; Timmerman, H; Wieland, K | 1 |
| Hastrup, S; Rimvall, K; Wulff, BS | 1 |
| Arrang, JM; Fkyerat, A; Ganellin, CR; Garbarg, M; Ligneau, X; Pelloux-Léon, N; Piripitsi, A; Schunack, W; Schwartz, JC; Stark, H; Tertiuk, W | 1 |
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Bitschnau, H; Kathmann, M; Marr, I; Reidemeister, S; Schlicker, E; Schunack, W; Stark, H | 1 |
| Arrang, JM; Ganellin, CR; Gbahou, F; Ligneau, X; Morisset, S; Schunack, W; Schwartz, JC; Stark, H; Tardivel-Lacombe, J | 1 |
| Arrang, JM; Cochois, V; Héron, A; Pillot, C; Rouleau, A; Schwartz, JC | 1 |
9 other study(ies) available for iodoproxyfan and thioperamide
| Article | Year |
|---|---|
[125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor.
Topics: Animals; Cerebral Cortex; Guinea Pigs; Histamine Antagonists; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Methylhistamines; Radioligand Assay; Rats; Structure-Activity Relationship | 1996 |
Different antagonist binding properties of human and rat histamine H3 receptors.
Topics: Animals; CHO Cells; Cricetinae; Female; Histamine Antagonists; Humans; Imidazoles; Models, Molecular; Protein Binding; Rats; Receptors, Histamine H3; Rhodopsin; Species Specificity | 2001 |
Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.
Topics: Animals; Benzyl Compounds; Cerebral Cortex; Guinea Pigs; Histamine Antagonists; Histamine Release; Imidazoles; In Vitro Techniques; Intestines; Ligands; Models, Molecular; Muscle Contraction; Muscle, Smooth; Piperidines; Quantitative Structure-Activity Relationship; Radioligand Assay; Rats; Receptors, Histamine H3; Software | 2001 |
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic | 2002 |
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.
Topics: Animals; Brain; Ethers; Histamine Agonists; Histamine Antagonists; Histamine Release; Imidazoles; Male; Methylhistamines; Mice; Rats; Receptors, Histamine H3; Structure-Activity Relationship; Sulfides; Synaptosomes | 2004 |
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Potencies of antagonists chemically related to iodoproxyfan at histamine H3 receptors in mouse brain cortex and guinea-pig ileum: evidence for H3 receptor heterogeneity?
Topics: Animals; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine Antagonists; Histamine H2 Antagonists; Imidazoles; In Vitro Techniques; Intestine, Small; Iodine Radioisotopes; Male; Methylhistamines; Mice; Piperidines; Rats; Rats, Wistar; Structure-Activity Relationship | 1996 |
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Binding, Competitive; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Histamine Antagonists; Humans; Imidazoles; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Histamine H3; Sequence Alignment; Sequence Homology, Amino Acid; Tritium | 2000 |
Cloning and expression of the mouse histamine H3 receptor: evidence for multiple isoforms.
Topics: Animals; Blotting, Northern; Brain; Chlorocebus aethiops; Cloning, Molecular; Competitive Bidding; COS Cells; Gene Expression; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; In Situ Hybridization; Iodine Radioisotopes; Isoenzymes; Mice; Piperidines; Radioligand Assay; Rats; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiourea; Transfection | 2004 |