Compounds > iodoproxyfan
Page last updated: 2024-09-04

iodoproxyfan and ciproxifan

iodoproxyfan has been researched along with ciproxifan in 6 studies

Compound Research Comparison

Studies
(iodoproxyfan)		Trials
(iodoproxyfan)		Recent Studies (post-2010)
(iodoproxyfan)		Studies
(ciproxifan)		Trials
(ciproxifan)		Recent Studies (post-2010) (ciproxifan)
2502106046

Protein Interaction Comparison

ProteinTaxonomyiodoproxyfan (IC50)ciproxifan (IC50)
Amine oxidase [flavin-containing] BHomo sapiens (human)2.0333

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arrang, JM; Ganellin, CR; Ligneau, X; Schunack, W; Schwartz, JC; Sippl, W; Stark, H1
Hastrup, S; Rimvall, K; Wulff, BS1
Elz, S; Ganellin, CR; Jouvet, M; Ligneau, X; Lin, J; Muir, JL; Schunack, W; Schwartz, J; Stark, H; Vanni-Mercier, G1
Kathmann, M; Marr, I; Schlicker, E; Schunack, W; Stark, H; Werthwein, S1
Arrang, JM; Morisset, S; Schwartz, JC; Traiffort, E1
Arrang, JM; Ganellin, CR; Gbahou, F; Ligneau, X; Morisset, S; Schunack, W; Schwartz, JC; Stark, H; Tardivel-Lacombe, J1

Other Studies

6 other study(ies) available for iodoproxyfan and ciproxifan

ArticleYear
Different antagonist binding properties of human and rat histamine H3 receptors.
    Bioorganic & medicinal chemistry letters, 2001, Apr-09, Volume: 11, Issue:7

    Topics: Animals; CHO Cells; Cricetinae; Female; Histamine Antagonists; Humans; Imidazoles; Models, Molecular; Protein Binding; Rats; Receptors, Histamine H3; Rhodopsin; Species Specificity

2001
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
    European journal of pharmacology, 2002, Oct-18, Volume: 453, Issue:1

    Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic

2002
Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Behavior, Animal; Cats; Electroencephalography; Female; Guinea Pigs; Histamine Antagonists; Imidazoles; Iodine Radioisotopes; Male; Methylhistamines; Mice; Neocortex; Radioligand Assay; Rats; Rats, Wistar; Receptors, Histamine H3

1998
Ciproxifan and chemically related compounds are highly potent and selective histamine H3-receptor antagonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:6

    Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Heart Atria; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Ileum; Imidazoles; In Vitro Techniques; Male; Mice; Models, Biological; Molecular Structure; Norepinephrine; Rats; Receptors, Histamine H3; Tritium

1998
Changes in histamine H3 receptor responsiveness in mouse brain.
    Journal of neurochemistry, 2000, Volume: 74, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Histamine Antagonists; Hypothalamus; Imidazoles; Male; Methylhistamines; Mice; Radioligand Assay; Receptors, Histamine H3

2000
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Binding, Competitive; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Histamine Antagonists; Humans; Imidazoles; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Histamine H3; Sequence Alignment; Sequence Homology, Amino Acid; Tritium

2000