interleukin-8 and cyanidin

interleukin-8 has been researched along with cyanidin* in 2 studies

Other Studies

2 other study(ies) available for interleukin-8 and cyanidin

Article	Year
Cyanidin chloride modestly protects Caco-2 cells from ZnO nanoparticle exposure probably through the induction of autophagy. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 127 Recent studies suggest that phytochemicals, as part of the food matrix, might alter the toxicity of nanoparticles (NPs); however, relatively few studies have investigated the impact of anthocyanidins on the toxicity of NPs to cells lining the gastrointestinal tract. Therefore, this study used cyanidin chloride (CC) as the model for anthocyanidins and investigated the effects of CC on the toxicity of ZnO or Ag NPs to Caco-2 cells. Exposure to ZnO but not Ag NPs significantly induced cytotoxicity. The presence of CC, but not its analog quercetin (Qu), modestly protected Caco-2 cells from ZnO NP exposure. However, the intracellular superoxide, Zn ions, or release of interleukin-8 after ZnO NP exposure were not significantly affected by the presence of CC. Rather, CC promoted the expression of autophagic genes ATG5, ATG7, and BECN1 as well as the ratio of LC3-II/I after exposure to ZnO NPs. Meanwhile, the presence of autophagic inhibitors (chloroquine, NH Topics: Anthocyanins; Autophagy; Biomarkers; Caco-2 Cells; Colloids; Cryoprotective Agents; Humans; Interleukin-8; Metal Nanoparticles; Microscopy, Electron, Transmission; Superoxides; Zinc; Zinc Oxide	2019
Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora). Journal of natural products, 2006, Volume: 69, Issue:8 A new depside, jaboticabin (1), together with 17 known compounds were isolated from the fruit of jaboticaba (Myrciaria cauliflora). The structure of 1 was elucidated by spectroscopic data interpretation. Known compounds were identified by comparison of their spectroscopic data with literature values or by comparison to authentic standards. Compound 1 and the related depside 2-O-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxyphenylacetic acid (2) significantly inhibited chemokine interleukin (IL)-8 production before and after cigarette smoke treatment of cells. Compound 1 was cytotoxic in the HT29 colon cancer cell line (IC50 = 65 microM), and 2 was active against HCT116 colon cancer cells (IC50 = 30 microM). Compounds 1 and 2 also exhibited antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (IC50 = 51.4 and 61.8 microM, respectively). Two anthocyanins, cyanidin 3-glucoside (3) and delphinidin 3-glucoside (4), also showed good activity in these assays. Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Depsides; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Hydroxybenzoates; Inhibitory Concentration 50; Interleukin-8; Molecular Structure; Myrtaceae; Nicotiana; Picrates; Smoke	2006

Article

Year

Cyanidin chloride modestly protects Caco-2 cells from ZnO nanoparticle exposure probably through the induction of autophagy.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 127

Recent studies suggest that phytochemicals, as part of the food matrix, might alter the toxicity of nanoparticles (NPs); however, relatively few studies have investigated the impact of anthocyanidins on the toxicity of NPs to cells lining the gastrointestinal tract. Therefore, this study used cyanidin chloride (CC) as the model for anthocyanidins and investigated the effects of CC on the toxicity of ZnO or Ag NPs to Caco-2 cells. Exposure to ZnO but not Ag NPs significantly induced cytotoxicity. The presence of CC, but not its analog quercetin (Qu), modestly protected Caco-2 cells from ZnO NP exposure. However, the intracellular superoxide, Zn ions, or release of interleukin-8 after ZnO NP exposure were not significantly affected by the presence of CC. Rather, CC promoted the expression of autophagic genes ATG5, ATG7, and BECN1 as well as the ratio of LC3-II/I after exposure to ZnO NPs. Meanwhile, the presence of autophagic inhibitors (chloroquine, NH

Topics: Anthocyanins; Autophagy; Biomarkers; Caco-2 Cells; Colloids; Cryoprotective Agents; Humans; Interleukin-8; Metal Nanoparticles; Microscopy, Electron, Transmission; Superoxides; Zinc; Zinc Oxide

2019

Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora).

Journal of natural products, 2006, Volume: 69, Issue:8

A new depside, jaboticabin (1), together with 17 known compounds were isolated from the fruit of jaboticaba (Myrciaria cauliflora). The structure of 1 was elucidated by spectroscopic data interpretation. Known compounds were identified by comparison of their spectroscopic data with literature values or by comparison to authentic standards. Compound 1 and the related depside 2-O-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxyphenylacetic acid (2) significantly inhibited chemokine interleukin (IL)-8 production before and after cigarette smoke treatment of cells. Compound 1 was cytotoxic in the HT29 colon cancer cell line (IC50 = 65 microM), and 2 was active against HCT116 colon cancer cells (IC50 = 30 microM). Compounds 1 and 2 also exhibited antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (IC50 = 51.4 and 61.8 microM, respectively). Two anthocyanins, cyanidin 3-glucoside (3) and delphinidin 3-glucoside (4), also showed good activity in these assays.

Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Depsides; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Hydroxybenzoates; Inhibitory Concentration 50; Interleukin-8; Molecular Structure; Myrtaceae; Nicotiana; Picrates; Smoke

2006